{"id":"https://openalex.org/W4310965535","doi":"https://doi.org/10.1021/acs.jcim.2c01316","title":"Prediction of Water Diffusion in Wide Varieties of Polymers with All-Atom Molecular Dynamics Simulations and Deep Generative Models","display_name":"Prediction of Water Diffusion in Wide Varieties of Polymers with All-Atom Molecular Dynamics Simulations and Deep Generative Models","publication_year":2022,"publication_date":"2022-12-07","ids":{"openalex":"https://openalex.org/W4310965535","doi":"https://doi.org/10.1021/acs.jcim.2c01316","pmid":"https://pubmed.ncbi.nlm.nih.gov/36475723"},"language":"en","primary_location":{"id":"doi:10.1021/acs.jcim.2c01316","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acs.jcim.2c01316","pdf_url":null,"source":{"id":"https://openalex.org/S167262187","display_name":"Journal of Chemical Information and Modeling","issn_l":"1549-9596","issn":["1549-9596","1549-960X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Chemical Information and Modeling","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060737891","display_name":"Ryo Kawada","orcid":"https://orcid.org/0000-0003-3498-707X"},"institutions":[{"id":"https://openalex.org/I203951103","display_name":"Keio University","ror":"https://ror.org/02kn6nx58","country_code":"JP","type":"education","lineage":["https://openalex.org/I203951103"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ryo Kawada","raw_affiliation_strings":["Department of Mechanical Engineering, Keio University, 3-14-1 Hiyoshi,\rKohoku-ku, Yokohama223-8522, Japan","Department of Mechanical Engineering, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama223-8522, Japan"],"affiliations":[{"raw_affiliation_string":"Department of Mechanical Engineering, Keio University, 3-14-1 Hiyoshi,\rKohoku-ku, Yokohama223-8522, Japan","institution_ids":["https://openalex.org/I203951103"]},{"raw_affiliation_string":"Department of Mechanical Engineering, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama223-8522, Japan","institution_ids":["https://openalex.org/I203951103"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054794415","display_name":"Katsuhiro Endo","orcid":"https://orcid.org/0000-0003-0689-9697"},"institutions":[{"id":"https://openalex.org/I203951103","display_name":"Keio University","ror":"https://ror.org/02kn6nx58","country_code":"JP","type":"education","lineage":["https://openalex.org/I203951103"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Katsuhiro Endo","raw_affiliation_strings":["Department of Mechanical Engineering, Keio University, 3-14-1 Hiyoshi,\rKohoku-ku, Yokohama223-8522, Japan","Department of Mechanical Engineering, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama223-8522, Japan"],"affiliations":[{"raw_affiliation_string":"Department of Mechanical Engineering, Keio University, 3-14-1 Hiyoshi,\rKohoku-ku, Yokohama223-8522, Japan","institution_ids":["https://openalex.org/I203951103"]},{"raw_affiliation_string":"Department of Mechanical Engineering, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama223-8522, Japan","institution_ids":["https://openalex.org/I203951103"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004379494","display_name":"Kenji Yasuoka","orcid":"https://orcid.org/0000-0002-4579-0195"},"institutions":[{"id":"https://openalex.org/I203951103","display_name":"Keio University","ror":"https://ror.org/02kn6nx58","country_code":"JP","type":"education","lineage":["https://openalex.org/I203951103"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Kenji Yasuoka","raw_affiliation_strings":["Department of Mechanical Engineering, Keio University, 3-14-1 Hiyoshi,\rKohoku-ku, Yokohama223-8522, Japan","Department of Mechanical Engineering, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama223-8522, Japan"],"affiliations":[{"raw_affiliation_string":"Department of Mechanical Engineering, Keio University, 3-14-1 Hiyoshi,\rKohoku-ku, Yokohama223-8522, Japan","institution_ids":["https://openalex.org/I203951103"]},{"raw_affiliation_string":"Department of Mechanical Engineering, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama223-8522, Japan","institution_ids":["https://openalex.org/I203951103"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110355055","display_name":"Hidekazu Kojima","orcid":null},"institutions":[{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hidekazu Kojima","raw_affiliation_strings":["Graduate School of Engineering Science, Osaka University, 1-3 Machikaneyama, Toyonaka, Osaka560-8531, Japan"],"affiliations":[{"raw_affiliation_string":"Graduate School of Engineering Science, Osaka University, 1-3 Machikaneyama, Toyonaka, Osaka560-8531, Japan","institution_ids":["https://openalex.org/I98285908"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026054733","display_name":"Nobuyuki Matubayasi","orcid":"https://orcid.org/0000-0001-7176-441X"},"institutions":[{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Nobuyuki Matubayasi","raw_affiliation_strings":["Graduate School of Engineering Science, Osaka University, 1-3 Machikaneyama, Toyonaka, Osaka560-8531, Japan"],"affiliations":[{"raw_affiliation_string":"Graduate School of Engineering Science, Osaka University, 1-3 Machikaneyama, Toyonaka, Osaka560-8531, Japan","institution_ids":["https://openalex.org/I98285908"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5004379494","https://openalex.org/A5026054733"],"corresponding_institution_ids":["https://openalex.org/I203951103","https://openalex.org/I98285908"],"apc_list":null,"apc_paid":null,"fwci":0.9001,"has_fulltext":false,"cited_by_count":14,"citation_normalized_percentile":{"value":0.70166631,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"63","issue":"1","first_page":"76","last_page":"86"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11948","display_name":"Machine Learning in Materials Science","score":0.9973000288009644,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11948","display_name":"Machine Learning in Materials Science","score":0.9973000288009644,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10409","display_name":"Fuel Cells and Related Materials","score":0.9958000183105469,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10389","display_name":"Polymer crystallization and properties","score":0.965499997138977,"subfield":{"id":"https://openalex.org/subfields/2507","display_name":"Polymers and Plastics"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mean-squared-displacement","display_name":"Mean squared displacement","score":0.7644122838973999},{"id":"https://openalex.org/keywords/molecular-dynamics","display_name":"Molecular dynamics","score":0.7340900897979736},{"id":"https://openalex.org/keywords/polymer","display_name":"Polymer","score":0.6026091575622559},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.5914955735206604},{"id":"https://openalex.org/keywords/diffusion","display_name":"Diffusion","score":0.5626714825630188},{"id":"https://openalex.org/keywords/atom","display_name":"Atom (system on chip)","score":0.5069625377655029},{"id":"https://openalex.org/keywords/permeation","display_name":"Permeation","score":0.4592539966106415},{"id":"https://openalex.org/keywords/correlation-coefficient","display_name":"Correlation coefficient","score":0.4528074264526367},{"id":"https://openalex.org/keywords/intermolecular-force","display_name":"Intermolecular force","score":0.44326502084732056},{"id":"https://openalex.org/keywords/chemical-physics","display_name":"Chemical physics","score":0.42688894271850586},{"id":"https://openalex.org/keywords/membrane","display_name":"Membrane","score":0.39140892028808594},{"id":"https://openalex.org/keywords/statistical-physics","display_name":"Statistical physics","score":0.34670180082321167},{"id":"https://openalex.org/keywords/molecule","display_name":"Molecule","score":0.33369171619415283},{"id":"https://openalex.org/keywords/thermodynamics","display_name":"Thermodynamics","score":0.32471179962158203},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3098400831222534},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.25498098134994507},{"id":"https://openalex.org/keywords/computational-chemistry","display_name":"Computational chemistry","score":0.21430239081382751},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.16022202372550964},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.13220888376235962},{"id":"https://openalex.org/keywords/organic-chemistry","display_name":"Organic chemistry","score":0.08847874402999878},{"id":"https://openalex.org/keywords/composite-material","display_name":"Composite material","score":0.08160525560379028}],"concepts":[{"id":"https://openalex.org/C187128312","wikidata":"https://www.wikidata.org/wiki/Q1565055","display_name":"Mean squared displacement","level":3,"score":0.7644122838973999},{"id":"https://openalex.org/C59593255","wikidata":"https://www.wikidata.org/wiki/Q901663","display_name":"Molecular dynamics","level":2,"score":0.7340900897979736},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.6026091575622559},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5914955735206604},{"id":"https://openalex.org/C69357855","wikidata":"https://www.wikidata.org/wiki/Q163214","display_name":"Diffusion","level":2,"score":0.5626714825630188},{"id":"https://openalex.org/C58312451","wikidata":"https://www.wikidata.org/wiki/Q4817200","display_name":"Atom (system on chip)","level":2,"score":0.5069625377655029},{"id":"https://openalex.org/C50670333","wikidata":"https://www.wikidata.org/wiki/Q907651","display_name":"Permeation","level":3,"score":0.4592539966106415},{"id":"https://openalex.org/C2780092901","wikidata":"https://www.wikidata.org/wiki/Q3433612","display_name":"Correlation coefficient","level":2,"score":0.4528074264526367},{"id":"https://openalex.org/C166950319","wikidata":"https://www.wikidata.org/wiki/Q245031","display_name":"Intermolecular force","level":3,"score":0.44326502084732056},{"id":"https://openalex.org/C159467904","wikidata":"https://www.wikidata.org/wiki/Q2001702","display_name":"Chemical physics","level":1,"score":0.42688894271850586},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.39140892028808594},{"id":"https://openalex.org/C121864883","wikidata":"https://www.wikidata.org/wiki/Q677916","display_name":"Statistical physics","level":1,"score":0.34670180082321167},{"id":"https://openalex.org/C32909587","wikidata":"https://www.wikidata.org/wiki/Q11369","display_name":"Molecule","level":2,"score":0.33369171619415283},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.32471179962158203},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3098400831222534},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.25498098134994507},{"id":"https://openalex.org/C147597530","wikidata":"https://www.wikidata.org/wiki/Q369472","display_name":"Computational chemistry","level":1,"score":0.21430239081382751},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.16022202372550964},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.13220888376235962},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.08847874402999878},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.08160525560379028},{"id":"https://openalex.org/C149635348","wikidata":"https://www.wikidata.org/wiki/Q193040","display_name":"Embedded system","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D004058","descriptor_name":"Diffusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004058","descriptor_name":"Diffusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004058","descriptor_name":"Diffusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011108","descriptor_name":"Polymers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011108","descriptor_name":"Polymers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011108","descriptor_name":"Polymers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D014867","descriptor_name":"Water","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D014867","descriptor_name":"Water","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D014867","descriptor_name":"Water","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D020959","descriptor_name":"Polyethylene","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020959","descriptor_name":"Polyethylene","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020959","descriptor_name":"Polyethylene","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056004","descriptor_name":"Molecular Dynamics Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D056004","descriptor_name":"Molecular Dynamics Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D056004","descriptor_name":"Molecular Dynamics Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1021/acs.jcim.2c01316","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acs.jcim.2c01316","pdf_url":null,"source":{"id":"https://openalex.org/S167262187","display_name":"Journal of Chemical Information and Modeling","issn_l":"1549-9596","issn":["1549-9596","1549-960X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Chemical Information and Modeling","raw_type":"journal-article"},{"id":"pmid:36475723","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36475723","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of chemical information and modeling","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1417125401","display_name":null,"funder_award_id":"JPMXP1020200308","funder_id":"https://openalex.org/F4320320912","funder_display_name":"Ministry of Education, Culture, Sports, Science and Technology"}],"funders":[{"id":"https://openalex.org/F4320320912","display_name":"Ministry of Education, Culture, Sports, Science and Technology","ror":"https://ror.org/048rj2z13"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":43,"referenced_works":["https://openalex.org/W622323056","https://openalex.org/W1489582602","https://openalex.org/W1965438743","https://openalex.org/W1972103123","https://openalex.org/W1973517344","https://openalex.org/W1976161355","https://openalex.org/W1976499671","https://openalex.org/W1981276685","https://openalex.org/W1993728228","https://openalex.org/W2012260221","https://openalex.org/W2025444507","https://openalex.org/W2035687084","https://openalex.org/W2047414254","https://openalex.org/W2052234083","https://openalex.org/W2057858097","https://openalex.org/W2063666345","https://openalex.org/W2080131977","https://openalex.org/W2083415705","https://openalex.org/W2092487929","https://openalex.org/W2103945336","https://openalex.org/W2128572087","https://openalex.org/W2134849720","https://openalex.org/W2147993766","https://openalex.org/W2165916500","https://openalex.org/W2515801595","https://openalex.org/W2547447472","https://openalex.org/W2585152223","https://openalex.org/W2728789193","https://openalex.org/W2788664391","https://openalex.org/W2884898669","https://openalex.org/W2913159621","https://openalex.org/W2948777210","https://openalex.org/W2957144537","https://openalex.org/W2963383782","https://openalex.org/W2969072345","https://openalex.org/W2973119841","https://openalex.org/W2988055229","https://openalex.org/W3082902407","https://openalex.org/W3101568640","https://openalex.org/W3192351850","https://openalex.org/W4205511145","https://openalex.org/W4244370844","https://openalex.org/W4307776419"],"related_works":["https://openalex.org/W2087572532","https://openalex.org/W1999630798","https://openalex.org/W2052761397","https://openalex.org/W3016508525","https://openalex.org/W2910661820","https://openalex.org/W2351859943","https://openalex.org/W2085342871","https://openalex.org/W1984299911","https://openalex.org/W3041285763","https://openalex.org/W2135418584"],"abstract_inverted_index":{"Permeation":[0],"through":[1],"polymer":[2],"membranes":[3],"is":[4,19,43,70],"an":[5,40],"important":[6],"technology":[7],"in":[8,13,63,72,90,109],"the":[9,16,22,29,57,116,123,141,151,161,180],"chemical":[10],"industry,":[11],"and":[12,35,51,75,104,120],"its":[14],"design,":[15],"self-diffusion":[17,30,118],"coefficient":[18,31,114,119],"one":[20],"of":[21,59,122,153,183],"physical":[23],"quantities":[24],"that":[25,121,131,173],"determine":[26],"permeability.":[27],"Since":[28],"sensitively":[32],"reflects":[33],"intra-":[34],"intermolecular":[36],"interactions,":[37],"analysis":[38],"using":[39],"all-atom":[41,46],"model":[42,162],"required.":[44],"However,":[45],"simulations":[47,74],"are":[48],"computationally":[49],"expensive":[50],"require":[52],"long":[53],"simulation":[54,125],"times":[55],"for":[56,82,179],"diffusion":[58,108],"small":[60],"molecules":[61],"dissolved":[62],"polymers.":[64,111],"MD-GAN,":[65],"a":[66],"machine":[67],"learning":[68],"model,":[69],"effective":[71],"accelerating":[73],"reducing":[76,140],"computational":[77],"costs.":[78],"The":[79,112],"target":[80],"systems":[81,99],"MD-GAN":[83,97,137],"prediction":[84,144],"were":[85],"limited":[86],"to":[87,98,148,165,169],"polyethylene":[88],"melts":[89],"previous":[91],"studies;":[92],"therefore,":[93],"this":[94],"study":[95],"extended":[96],"containing":[100],"copolymers":[101],"with":[102,156],"branches":[103],"successfully":[105],"predicted":[106,117],"water":[107],"various":[110],"correlation":[113],"between":[115],"long-time":[124],"was":[126,163],"1.00.":[127],"Additionally,":[128],"we":[129],"found":[130,164],"incorporating":[132],"statistical":[133],"domain":[134],"knowledge":[135],"into":[136],"improved":[138],"accuracy,":[139],"mean-square":[142],"displacement":[143],"outliers":[145],"from":[146],"14.6%":[147],"5.3%.":[149],"Lastly,":[150],"distribution":[152],"latent":[154],"variables":[155],"embedded":[157],"dynamics":[158],"information":[159],"within":[160],"be":[166,177],"strongly":[167],"related":[168],"accuracy.":[170],"We":[171],"believe":[172],"these":[174],"findings":[175],"can":[176],"useful":[178],"practical":[181],"applications":[182],"MD-GAN.":[184]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":1}],"updated_date":"2026-03-27T05:58:40.876381","created_date":"2025-10-10T00:00:00"}