{"id":"https://openalex.org/W4250095149","doi":"https://doi.org/10.1017/s0021900200011359","title":"A Crump-Mode-Jagers Branching Process Model of Prion Loss in Yeast","display_name":"A Crump-Mode-Jagers Branching Process Model of Prion Loss in Yeast","publication_year":2014,"publication_date":"2014-06-01","ids":{"openalex":"https://openalex.org/W4250095149","doi":"https://doi.org/10.1017/s0021900200011359"},"language":"en","primary_location":{"id":"doi:10.1017/s0021900200011359","is_oa":true,"landing_page_url":"https://doi.org/10.1017/s0021900200011359","pdf_url":"https://www.cambridge.org/core/services/aop-cambridge-core/content/view/34DC5453D763117D168F51F8DB1DAA23/S0021900200011359a.pdf/div-class-title-a-crump-mode-jagers-branching-process-model-of-prion-loss-in-yeast-div.pdf","source":{"id":"https://openalex.org/S160779208","display_name":"Journal of Applied Probability","issn_l":"0021-9002","issn":["0021-9002","1475-6072"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310311721","host_organization_name":"Cambridge University Press","host_organization_lineage":["https://openalex.org/P4310311721","https://openalex.org/P4310311702"],"host_organization_lineage_names":["Cambridge University Press","University of Cambridge"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Applied Probability","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.cambridge.org/core/services/aop-cambridge-core/content/view/34DC5453D763117D168F51F8DB1DAA23/S0021900200011359a.pdf/div-class-title-a-crump-mode-jagers-branching-process-model-of-prion-loss-in-yeast-div.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5081146964","display_name":"Peter Olofsson","orcid":"https://orcid.org/0000-0002-4528-5658"},"institutions":[{"id":"https://openalex.org/I60060512","display_name":"Trinity University","ror":"https://ror.org/00t8gz605","country_code":"US","type":"education","lineage":["https://openalex.org/I60060512"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Peter Olofsson","raw_affiliation_strings":["Trinity University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Trinity University","institution_ids":["https://openalex.org/I60060512"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027970835","display_name":"Suzanne Sindi","orcid":"https://orcid.org/0000-0003-2742-4332"},"institutions":[{"id":"https://openalex.org/I156087764","display_name":"University of California, Merced","ror":"https://ror.org/00d9ah105","country_code":"US","type":"education","lineage":["https://openalex.org/I156087764"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Suzanne S. Sindi","raw_affiliation_strings":["University of California, Merced"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California, Merced","institution_ids":["https://openalex.org/I156087764"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5027970835","https://openalex.org/A5081146964"],"corresponding_institution_ids":["https://openalex.org/I156087764","https://openalex.org/I60060512"],"apc_list":null,"apc_paid":null,"fwci":0.2845,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.62033944,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"51","issue":"02","first_page":"453","last_page":"465"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11335","display_name":"Prion Diseases and Protein Misfolding","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11335","display_name":"Prion Diseases and Protein Misfolding","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10855","display_name":"Amyotrophic Lateral Sclerosis Research","score":0.9185000061988831,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/yeast","display_name":"Yeast","score":0.8442425727844238},{"id":"https://openalex.org/keywords/branching-process","display_name":"Branching process","score":0.6656285524368286},{"id":"https://openalex.org/keywords/saccharomyces-cerevisiae","display_name":"Saccharomyces cerevisiae","score":0.6597693562507629},{"id":"https://openalex.org/keywords/branching","display_name":"Branching (polymer chemistry)","score":0.5773520469665527},{"id":"https://openalex.org/keywords/exponential-growth","display_name":"Exponential growth","score":0.5756033658981323},{"id":"https://openalex.org/keywords/prion-proteins","display_name":"Prion Proteins","score":0.5032443404197693},{"id":"https://openalex.org/keywords/cell-division","display_name":"Cell division","score":0.4579010307788849},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.4535279870033264},{"id":"https://openalex.org/keywords/prion-protein","display_name":"Prion protein","score":0.40718284249305725},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.364444375038147},{"id":"https://openalex.org/keywords/cell","display_name":"Cell","score":0.29357752203941345},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.2230353057384491},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.19144561886787415},{"id":"https://openalex.org/keywords/combinatorics","display_name":"Combinatorics","score":0.14235281944274902},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.0809478759765625},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.07960587739944458},{"id":"https://openalex.org/keywords/mathematical-analysis","display_name":"Mathematical analysis","score":0.07028737664222717}],"concepts":[{"id":"https://openalex.org/C2779222958","wikidata":"https://www.wikidata.org/wiki/Q45422","display_name":"Yeast","level":2,"score":0.8442425727844238},{"id":"https://openalex.org/C177255742","wikidata":"https://www.wikidata.org/wiki/Q4109953","display_name":"Branching process","level":2,"score":0.6656285524368286},{"id":"https://openalex.org/C2777576037","wikidata":"https://www.wikidata.org/wiki/Q719725","display_name":"Saccharomyces cerevisiae","level":3,"score":0.6597693562507629},{"id":"https://openalex.org/C206175624","wikidata":"https://www.wikidata.org/wiki/Q595731","display_name":"Branching (polymer chemistry)","level":2,"score":0.5773520469665527},{"id":"https://openalex.org/C75235859","wikidata":"https://www.wikidata.org/wiki/Q582659","display_name":"Exponential growth","level":2,"score":0.5756033658981323},{"id":"https://openalex.org/C2909371084","wikidata":"https://www.wikidata.org/wiki/Q14881255","display_name":"Prion Proteins","level":4,"score":0.5032443404197693},{"id":"https://openalex.org/C85813293","wikidata":"https://www.wikidata.org/wiki/Q188909","display_name":"Cell division","level":3,"score":0.4579010307788849},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.4535279870033264},{"id":"https://openalex.org/C3019804061","wikidata":"https://www.wikidata.org/wiki/Q14881255","display_name":"Prion protein","level":3,"score":0.40718284249305725},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.364444375038147},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.29357752203941345},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2230353057384491},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.19144561886787415},{"id":"https://openalex.org/C114614502","wikidata":"https://www.wikidata.org/wiki/Q76592","display_name":"Combinatorics","level":1,"score":0.14235281944274902},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0809478759765625},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.07960587739944458},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.07028737664222717},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1017/s0021900200011359","is_oa":true,"landing_page_url":"https://doi.org/10.1017/s0021900200011359","pdf_url":"https://www.cambridge.org/core/services/aop-cambridge-core/content/view/34DC5453D763117D168F51F8DB1DAA23/S0021900200011359a.pdf/div-class-title-a-crump-mode-jagers-branching-process-model-of-prion-loss-in-yeast-div.pdf","source":{"id":"https://openalex.org/S160779208","display_name":"Journal of Applied Probability","issn_l":"0021-9002","issn":["0021-9002","1475-6072"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310311721","host_organization_name":"Cambridge University Press","host_organization_lineage":["https://openalex.org/P4310311721","https://openalex.org/P4310311702"],"host_organization_lineage_names":["Cambridge University Press","University of Cambridge"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Applied Probability","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1017/s0021900200011359","is_oa":true,"landing_page_url":"https://doi.org/10.1017/s0021900200011359","pdf_url":"https://www.cambridge.org/core/services/aop-cambridge-core/content/view/34DC5453D763117D168F51F8DB1DAA23/S0021900200011359a.pdf/div-class-title-a-crump-mode-jagers-branching-process-model-of-prion-loss-in-yeast-div.pdf","source":{"id":"https://openalex.org/S160779208","display_name":"Journal of Applied Probability","issn_l":"0021-9002","issn":["0021-9002","1475-6072"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310311721","host_organization_name":"Cambridge University Press","host_organization_lineage":["https://openalex.org/P4310311721","https://openalex.org/P4310311702"],"host_organization_lineage_names":["Cambridge University Press","University of Cambridge"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Applied Probability","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1983959847","display_name":null,"funder_award_id":"1R15GM093957-01","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4250095149.pdf","grobid_xml":"https://content.openalex.org/works/W4250095149.grobid-xml"},"referenced_works_count":21,"referenced_works":["https://openalex.org/W1978959047","https://openalex.org/W1978984155","https://openalex.org/W1994561364","https://openalex.org/W1998024248","https://openalex.org/W2010745676","https://openalex.org/W2013679718","https://openalex.org/W2014540834","https://openalex.org/W2036404841","https://openalex.org/W2062076246","https://openalex.org/W2070743881","https://openalex.org/W2084910695","https://openalex.org/W2085991232","https://openalex.org/W2098159151","https://openalex.org/W2125019567","https://openalex.org/W2130088593","https://openalex.org/W2130896726","https://openalex.org/W2141389019","https://openalex.org/W2160594729","https://openalex.org/W2316151760","https://openalex.org/W2316183460","https://openalex.org/W4302769472"],"related_works":["https://openalex.org/W2030362416","https://openalex.org/W3182923139","https://openalex.org/W1992659255","https://openalex.org/W2495881002","https://openalex.org/W4319915613","https://openalex.org/W2798655486","https://openalex.org/W2085783822","https://openalex.org/W3160503995","https://openalex.org/W2148761945","https://openalex.org/W2587631411"],"abstract_inverted_index":{"The":[0],"yeast":[1,56,77],"Saccharomyces":[2],"cerevisiae":[3],"has":[4],"emerged":[5],"as":[6,96],"an":[7,31,90],"ideal":[8],"model":[9,74],"system":[10],"to":[11],"study":[12],"the":[13],"dynamics":[14],"of":[15,24,75,81],"prion":[16,34,82,94],"proteins":[17,35],"which":[18,39],"are":[19,48,65],"responsible":[20],"for":[21],"a":[22,62,70,76],"number":[23],"fatal":[25],"neurodegenerative":[26],"diseases":[27],"in":[28,37,42,55],"humans.":[29],"Within":[30],"infected":[32],"cell,":[33],"aggregate":[36,100],"complexes":[38],"may":[40],"increase":[41],"size":[43,64],"or":[44],"be":[45],"fragmented":[46],"and":[47,102],"transmitted":[49,66],"upon":[50],"cell":[51],"division.":[52],"Recent":[53],"work":[54],"suggests":[57],"that":[58],"only":[59],"aggregates":[60],"below":[61],"critical":[63],"efficiently.":[67],"We":[68,84],"formulate":[69],"continuous-time":[71],"branching":[72],"process":[73],"colony":[78],"under":[79],"conditions":[80],"curing.":[83],"generalize":[85],"previous":[86],"approaches":[87],"by":[88,98],"providing":[89],"explicit":[91],"formula":[92],"approximating":[93],"loss":[95],"influenced":[97],"both":[99],"growth":[101],"size-dependent":[103],"transmission.":[104]},"counts_by_year":[{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2026-05-21T06:26:12.895304","created_date":"2025-10-10T00:00:00"}