{"id":"https://openalex.org/W4309913728","doi":"https://doi.org/10.1016/j.neuroimage.2022.119763","title":"An optimized reference tissue method for quantification of tau protein depositions in diverse neurodegenerative disorders by PET with 18F-PM-PBB3 (18F-APN-1607)","display_name":"An optimized reference tissue method for quantification of tau protein depositions in diverse neurodegenerative disorders by PET with 18F-PM-PBB3 (18F-APN-1607)","publication_year":2022,"publication_date":"2022-11-24","ids":{"openalex":"https://openalex.org/W4309913728","doi":"https://doi.org/10.1016/j.neuroimage.2022.119763","pmid":"https://pubmed.ncbi.nlm.nih.gov/36427751"},"language":"en","primary_location":{"id":"doi:10.1016/j.neuroimage.2022.119763","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.neuroimage.2022.119763","pdf_url":null,"source":{"id":"https://openalex.org/S103225281","display_name":"NeuroImage","issn_l":"1053-8119","issn":["1053-8119","1095-9572"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroImage","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1016/j.neuroimage.2022.119763","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079225739","display_name":"Kenji Tagai","orcid":"https://orcid.org/0000-0002-4551-1491"},"institutions":[{"id":"https://openalex.org/I115498069","display_name":"Jikei University School of Medicine","ror":"https://ror.org/039ygjf22","country_code":"JP","type":"education","lineage":["https://openalex.org/I115498069"]},{"id":"https://openalex.org/I4210114217","display_name":"National Institutes for Quantum Science and Technology","ror":"https://ror.org/020rbyg91","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210114217"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Kenji Tagai","raw_affiliation_strings":["Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan; Department of Psychiatry, The Jikei University of Medicine, Tokyo 105-8461, Japan. Electronic address: tagai.kenji@qst.go.jp","Department of Psychiatry, The Jikei University of Medicine, Tokyo 105-8461, Japan","Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan"],"affiliations":[{"raw_affiliation_string":"Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan; Department of Psychiatry, The Jikei University of Medicine, Tokyo 105-8461, Japan. Electronic address: tagai.kenji@qst.go.jp","institution_ids":["https://openalex.org/I4210114217"]},{"raw_affiliation_string":"Department of Psychiatry, The Jikei University of Medicine, Tokyo 105-8461, Japan","institution_ids":["https://openalex.org/I115498069"]},{"raw_affiliation_string":"Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan","institution_ids":["https://openalex.org/I4210114217"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100989798","display_name":"Yoko Ikoma","orcid":null},"institutions":[{"id":"https://openalex.org/I4210114217","display_name":"National Institutes for Quantum Science and Technology","ror":"https://ror.org/020rbyg91","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210114217"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoko Ikoma","raw_affiliation_strings":["Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan"],"affiliations":[{"raw_affiliation_string":"Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan","institution_ids":["https://openalex.org/I4210114217"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035701410","display_name":"Hironobu Endo","orcid":"https://orcid.org/0000-0003-3398-597X"},"institutions":[{"id":"https://openalex.org/I4210114217","display_name":"National Institutes for Quantum Science and Technology","ror":"https://ror.org/020rbyg91","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210114217"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hironobu Endo","raw_affiliation_strings":["Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan"],"affiliations":[{"raw_affiliation_string":"Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan","institution_ids":["https://openalex.org/I4210114217"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047822872","display_name":"Oiendrila Bhowmik Debnath","orcid":"https://orcid.org/0000-0003-3307-8042"},"institutions":[{"id":"https://openalex.org/I4210114217","display_name":"National Institutes for Quantum Science and Technology","ror":"https://ror.org/020rbyg91","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210114217"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Oiendrila Bhowmik Debnath","raw_affiliation_strings":["Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan"],"affiliations":[{"raw_affiliation_string":"Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan","institution_ids":["https://openalex.org/I4210114217"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060847562","display_name":"Chie Seki","orcid":"https://orcid.org/0000-0002-3222-7125"},"institutions":[{"id":"https://openalex.org/I4210114217","display_name":"National Institutes for Quantum Science and Technology","ror":"https://ror.org/020rbyg91","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210114217"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Chie Seki","raw_affiliation_strings":["Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan"],"affiliations":[{"raw_affiliation_string":"Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan","institution_ids":["https://openalex.org/I4210114217"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048387675","display_name":"Kiwamu Matsuoka","orcid":"https://orcid.org/0000-0003-3263-0958"},"institutions":[{"id":"https://openalex.org/I4210114217","display_name":"National Institutes for Quantum Science and Technology","ror":"https://ror.org/020rbyg91","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210114217"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kiwamu Matsuoka","raw_affiliation_strings":["Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan"],"affiliations":[{"raw_affiliation_string":"Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan","institution_ids":["https://openalex.org/I4210114217"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090325884","display_name":"Hideki Matsumoto","orcid":"https://orcid.org/0000-0002-8057-9598"},"institutions":[{"id":"https://openalex.org/I4210114217","display_name":"National Institutes for Quantum Science and Technology","ror":"https://ror.org/020rbyg91","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210114217"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hideki Matsumoto","raw_affiliation_strings":["Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan"],"affiliations":[{"raw_affiliation_string":"Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan","institution_ids":["https://openalex.org/I4210114217"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015359046","display_name":"Masaki Oya","orcid":null},"institutions":[{"id":"https://openalex.org/I4210114217","display_name":"National Institutes for Quantum Science and Technology","ror":"https://ror.org/020rbyg91","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210114217"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masaki Oya","raw_affiliation_strings":["Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan"],"affiliations":[{"raw_affiliation_string":"Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan","institution_ids":["https://openalex.org/I4210114217"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068994256","display_name":"Kosei Hirata","orcid":"https://orcid.org/0009-0007-9027-9277"},"institutions":[{"id":"https://openalex.org/I4210114217","display_name":"National Institutes for Quantum Science and Technology","ror":"https://ror.org/020rbyg91","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210114217"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kosei Hirata","raw_affiliation_strings":["Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan"],"affiliations":[{"raw_affiliation_string":"Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan","institution_ids":["https://openalex.org/I4210114217"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089307173","display_name":"Hitoshi Shinotoh","orcid":"https://orcid.org/0000-0003-1726-8268"},"institutions":[{"id":"https://openalex.org/I4210114217","display_name":"National Institutes for Quantum Science and Technology","ror":"https://ror.org/020rbyg91","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210114217"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hitoshi Shinotoh","raw_affiliation_strings":["Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan"],"affiliations":[{"raw_affiliation_string":"Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan","institution_ids":["https://openalex.org/I4210114217"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009790212","display_name":"Keisuke Takahata","orcid":"https://orcid.org/0000-0002-0884-4924"},"institutions":[{"id":"https://openalex.org/I203951103","display_name":"Keio University","ror":"https://ror.org/02kn6nx58","country_code":"JP","type":"education","lineage":["https://openalex.org/I203951103"]},{"id":"https://openalex.org/I4210114217","display_name":"National Institutes for Quantum Science and Technology","ror":"https://ror.org/020rbyg91","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210114217"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Keisuke Takahata","raw_affiliation_strings":["Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan; Department of Psychiatry, Keio University School of Medicine, Tokyo 160-0016, Japan","Department of Psychiatry, Keio University School of Medicine, Tokyo 160-0016, Japan","Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan"],"affiliations":[{"raw_affiliation_string":"Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan; Department of Psychiatry, Keio University School of Medicine, Tokyo 160-0016, Japan","institution_ids":["https://openalex.org/I4210114217"]},{"raw_affiliation_string":"Department of Psychiatry, Keio University School of Medicine, Tokyo 160-0016, Japan","institution_ids":["https://openalex.org/I203951103"]},{"raw_affiliation_string":"Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan","institution_ids":["https://openalex.org/I4210114217"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026143979","display_name":"Shin Kurose","orcid":"https://orcid.org/0000-0001-8355-4946"},"institutions":[{"id":"https://openalex.org/I203951103","display_name":"Keio University","ror":"https://ror.org/02kn6nx58","country_code":"JP","type":"education","lineage":["https://openalex.org/I203951103"]},{"id":"https://openalex.org/I4210114217","display_name":"National Institutes for Quantum Science and Technology","ror":"https://ror.org/020rbyg91","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210114217"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shin Kurose","raw_affiliation_strings":["Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan; Department of Psychiatry, Keio University School of Medicine, Tokyo 160-0016, Japan","Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan","Department of Psychiatry, Keio University School of Medicine, Tokyo 160-0016, Japan"],"affiliations":[{"raw_affiliation_string":"Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan; Department of Psychiatry, Keio University School of Medicine, Tokyo 160-0016, Japan","institution_ids":["https://openalex.org/I4210114217"]},{"raw_affiliation_string":"Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan","institution_ids":["https://openalex.org/I4210114217"]},{"raw_affiliation_string":"Department of Psychiatry, Keio University School of Medicine, Tokyo 160-0016, Japan","institution_ids":["https://openalex.org/I203951103"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110851020","display_name":"Yasunori Sano","orcid":null},"institutions":[{"id":"https://openalex.org/I203951103","display_name":"Keio University","ror":"https://ror.org/02kn6nx58","country_code":"JP","type":"education","lineage":["https://openalex.org/I203951103"]},{"id":"https://openalex.org/I4210114217","display_name":"National Institutes for Quantum Science and Technology","ror":"https://ror.org/020rbyg91","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210114217"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yasunori Sano","raw_affiliation_strings":["Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan; Department of Psychiatry, Keio University School of Medicine, Tokyo 160-0016, Japan","Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan","Department of Psychiatry, Keio University School of Medicine, Tokyo 160-0016, Japan"],"affiliations":[{"raw_affiliation_string":"Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan; Department of Psychiatry, Keio University School of Medicine, Tokyo 160-0016, Japan","institution_ids":["https://openalex.org/I4210114217"]},{"raw_affiliation_string":"Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan","institution_ids":["https://openalex.org/I4210114217"]},{"raw_affiliation_string":"Department of Psychiatry, Keio University School of Medicine, Tokyo 160-0016, Japan","institution_ids":["https://openalex.org/I203951103"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064186453","display_name":"Maiko Ono","orcid":"https://orcid.org/0000-0003-2239-1754"},"institutions":[{"id":"https://openalex.org/I4210114217","display_name":"National Institutes for Quantum Science and Technology","ror":"https://ror.org/020rbyg91","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210114217"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Maiko Ono","raw_affiliation_strings":["Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan"],"affiliations":[{"raw_affiliation_string":"Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan","institution_ids":["https://openalex.org/I4210114217"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069308721","display_name":"Hitoshi Shimada","orcid":"https://orcid.org/0000-0002-7139-7178"},"institutions":[{"id":"https://openalex.org/I4210114217","display_name":"National Institutes for Quantum Science and Technology","ror":"https://ror.org/020rbyg91","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210114217"]},{"id":"https://openalex.org/I71395657","display_name":"Niigata University","ror":"https://ror.org/04ww21r56","country_code":"JP","type":"education","lineage":["https://openalex.org/I71395657"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hitoshi Shimada","raw_affiliation_strings":["Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan; Department of Functional Neurology & Neurosurgery, Center for Integrated Human Brain Science, Brain Research Institute, Niigata University, Niigata 951-8585, Japan","Department of Functional Neurology & Neurosurgery, Center for Integrated Human Brain Science, Brain Research Institute, Niigata University, Niigata 951-8585, Japan","Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan"],"affiliations":[{"raw_affiliation_string":"Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan; Department of Functional Neurology & Neurosurgery, Center for Integrated Human Brain Science, Brain Research Institute, Niigata University, Niigata 951-8585, Japan","institution_ids":["https://openalex.org/I4210114217"]},{"raw_affiliation_string":"Department of Functional Neurology & Neurosurgery, Center for Integrated Human Brain Science, Brain Research Institute, Niigata University, Niigata 951-8585, Japan","institution_ids":["https://openalex.org/I71395657"]},{"raw_affiliation_string":"Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan","institution_ids":["https://openalex.org/I4210114217"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064403117","display_name":"Kazunori Kawamura","orcid":"https://orcid.org/0000-0001-6786-678X"},"institutions":[{"id":"https://openalex.org/I4210114217","display_name":"National Institutes for Quantum Science and Technology","ror":"https://ror.org/020rbyg91","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210114217"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazunori Kawamura","raw_affiliation_strings":["Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan"],"affiliations":[{"raw_affiliation_string":"Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan","institution_ids":["https://openalex.org/I4210114217"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030087345","display_name":"Ming\u2010Rong Zhang","orcid":"https://orcid.org/0000-0002-3001-9605"},"institutions":[{"id":"https://openalex.org/I4210114217","display_name":"National Institutes for Quantum Science and Technology","ror":"https://ror.org/020rbyg91","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210114217"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ming-Rong Zhang","raw_affiliation_strings":["Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan"],"affiliations":[{"raw_affiliation_string":"Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan","institution_ids":["https://openalex.org/I4210114217"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039084458","display_name":"Yuhei Takado","orcid":"https://orcid.org/0000-0001-7484-8424"},"institutions":[{"id":"https://openalex.org/I4210114217","display_name":"National Institutes for Quantum Science and Technology","ror":"https://ror.org/020rbyg91","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210114217"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Yuhei Takado","raw_affiliation_strings":["Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan. Electronic address: takado.yuhei@qst.go.jp","Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan"],"affiliations":[{"raw_affiliation_string":"Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan. Electronic address: takado.yuhei@qst.go.jp","institution_ids":["https://openalex.org/I4210114217"]},{"raw_affiliation_string":"Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan","institution_ids":["https://openalex.org/I4210114217"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5002819177","display_name":"Makoto Higuchi","orcid":"https://orcid.org/0000-0002-3934-5810"},"institutions":[{"id":"https://openalex.org/I4210114217","display_name":"National Institutes for Quantum Science and Technology","ror":"https://ror.org/020rbyg91","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210114217"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Makoto Higuchi","raw_affiliation_strings":["Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan"],"affiliations":[{"raw_affiliation_string":"Quantum Life and Medical Science Directorate, National Institutes for Quantum Science and Technology, Institute for Quantum Medical Science, Chiba 263-8555, Japan","institution_ids":["https://openalex.org/I4210114217"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":19,"corresponding_author_ids":["https://openalex.org/A5039084458","https://openalex.org/A5079225739"],"corresponding_institution_ids":["https://openalex.org/I115498069","https://openalex.org/I4210114217"],"apc_list":{"value":3450,"currency":"USD","value_usd":3450},"apc_paid":{"value":3450,"currency":"USD","value_usd":3450},"fwci":2.4785,"has_fulltext":false,"cited_by_count":21,"citation_normalized_percentile":{"value":0.9040979,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"264","issue":null,"first_page":"119763","last_page":"119763"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.991599977016449,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.991599977016449,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12030","display_name":"S100 Proteins and Annexins","score":0.9786999821662903,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.9745000004768372,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/brain-tissue","display_name":"Brain tissue","score":0.5253735780715942},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.43598711490631104},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.3609517812728882},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.34477946162223816},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.27204081416130066}],"concepts":[{"id":"https://openalex.org/C2986936838","wikidata":"https://www.wikidata.org/wiki/Q492038","display_name":"Brain tissue","level":2,"score":0.5253735780715942},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.43598711490631104},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3609517812728882},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.34477946162223816},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.27204081416130066}],"mesh":[{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002531","descriptor_name":"Cerebellum","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D002531","descriptor_name":"Cerebellum","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D002531","descriptor_name":"Cerebellum","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D002531","descriptor_name":"Cerebellum","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D002531","descriptor_name":"Cerebellum","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D002531","descriptor_name":"Cerebellum","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012015","descriptor_name":"Reference Standards","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012015","descriptor_name":"Reference Standards","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012015","descriptor_name":"Reference Standards","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013494","descriptor_name":"Supranuclear Palsy, Progressive","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D013494","descriptor_name":"Supranuclear Palsy, Progressive","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D013494","descriptor_name":"Supranuclear Palsy, Progressive","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D013494","descriptor_name":"Supranuclear Palsy, Progressive","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D013494","descriptor_name":"Supranuclear Palsy, Progressive","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D013494","descriptor_name":"Supranuclear Palsy, Progressive","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D016875","descriptor_name":"tau Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D016875","descriptor_name":"tau Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D016875","descriptor_name":"tau Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D016875","descriptor_name":"tau Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D016875","descriptor_name":"tau Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D016875","descriptor_name":"tau Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D024801","descriptor_name":"Tauopathies","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D024801","descriptor_name":"Tauopathies","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D024801","descriptor_name":"Tauopathies","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D024801","descriptor_name":"Tauopathies","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D024801","descriptor_name":"Tauopathies","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D024801","descriptor_name":"Tauopathies","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D049268","descriptor_name":"Positron-Emission Tomography","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true},{"descriptor_ui":"D049268","descriptor_name":"Positron-Emission Tomography","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true},{"descriptor_ui":"D049268","descriptor_name":"Positron-Emission Tomography","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true},{"descriptor_ui":"D057180","descriptor_name":"Frontotemporal Dementia","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D057180","descriptor_name":"Frontotemporal Dementia","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D057180","descriptor_name":"Frontotemporal Dementia","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D057180","descriptor_name":"Frontotemporal Dementia","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D057180","descriptor_name":"Frontotemporal Dementia","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D057180","descriptor_name":"Frontotemporal Dementia","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.neuroimage.2022.119763","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.neuroimage.2022.119763","pdf_url":null,"source":{"id":"https://openalex.org/S103225281","display_name":"NeuroImage","issn_l":"1053-8119","issn":["1053-8119","1095-9572"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroImage","raw_type":"journal-article"},{"id":"pmid:36427751","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36427751","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroImage","raw_type":null},{"id":"pmh:oai:doaj.org/article:35a5b66d8dcc4f59a4b9f23e33fa7ea0","is_oa":true,"landing_page_url":"https://doaj.org/article/35a5b66d8dcc4f59a4b9f23e33fa7ea0","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"NeuroImage, Vol 264, Iss , Pp 119763- (2022)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.neuroimage.2022.119763","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.neuroimage.2022.119763","pdf_url":null,"source":{"id":"https://openalex.org/S103225281","display_name":"NeuroImage","issn_l":"1053-8119","issn":["1053-8119","1095-9572"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroImage","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.6299999952316284,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[{"id":"https://openalex.org/G171938454","display_name":null,"funder_award_id":"20356533","funder_id":"https://openalex.org/F4320311405","funder_display_name":"Japan Agency for Medical Research and Development"},{"id":"https://openalex.org/G2601840180","display_name":null,"funder_award_id":"21ek0109474h0002","funder_id":"https://openalex.org/F4320311405","funder_display_name":"Japan Agency for Medical Research and Development"},{"id":"https://openalex.org/G273676685","display_name":null,"funder_award_id":"JP22K15776","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G2737584612","display_name":null,"funder_award_id":"JPMJMS2024","funder_id":"https://openalex.org/F4320334789","funder_display_name":"Japan Science and Technology Agency"},{"id":"https://openalex.org/G3118131176","display_name":null,"funder_award_id":"JP18dk0207026","funder_id":"https://openalex.org/F4320311405","funder_display_name":"Japan Agency for Medical Research and Development"},{"id":"https://openalex.org/G3301964346","display_name":null,"funder_award_id":"JP19dm0207072","funder_id":"https://openalex.org/F4320311405","funder_display_name":"Japan Agency for Medical Research and Development"},{"id":"https://openalex.org/G5000518628","display_name":null,"funder_award_id":"JP16H05324","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G5746581886","display_name":null,"funder_award_id":"21wm0425015h0001","funder_id":"https://openalex.org/F4320311405","funder_display_name":"Japan Agency for Medical Research and Development"},{"id":"https://openalex.org/G7154852255","display_name":null,"funder_award_id":"JP18K07543","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G7167431327","display_name":null,"funder_award_id":"JPMJCR1652","funder_id":"https://openalex.org/F4320334789","funder_display_name":"Japan Science and Technology Agency"},{"id":"https://openalex.org/G8222088012","display_name":null,"funder_award_id":"JP18dm0207018","funder_id":"https://openalex.org/F4320311405","funder_display_name":"Japan Agency for Medical Research and Development"}],"funders":[{"id":"https://openalex.org/F4320308604","display_name":"Biogen","ror":"https://ror.org/02jqkb192"},{"id":"https://openalex.org/F4320311405","display_name":"Japan Agency for Medical Research and Development","ror":"https://ror.org/004rtk039"},{"id":"https://openalex.org/F4320320912","display_name":"Ministry of Education, Culture, Sports, Science and Technology","ror":"https://ror.org/048rj2z13"},{"id":"https://openalex.org/F4320324809","display_name":"Jikei University School of Medicine","ror":"https://ror.org/039ygjf22"},{"id":"https://openalex.org/F4320325182","display_name":"Chiba University","ror":"https://ror.org/01hjzeq58"},{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"},{"id":"https://openalex.org/F4320334789","display_name":"Japan Science and Technology Agency","ror":"https://ror.org/00097mb19"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":41,"referenced_works":["https://openalex.org/W1600934558","https://openalex.org/W1999460867","https://openalex.org/W2004136146","https://openalex.org/W2009870816","https://openalex.org/W2018765794","https://openalex.org/W2019587683","https://openalex.org/W2044731489","https://openalex.org/W2102150307","https://openalex.org/W2128030851","https://openalex.org/W2138190873","https://openalex.org/W2143195814","https://openalex.org/W2144707045","https://openalex.org/W2156220037","https://openalex.org/W2159122349","https://openalex.org/W2257069458","https://openalex.org/W2272994097","https://openalex.org/W2294884050","https://openalex.org/W2336609159","https://openalex.org/W2339635935","https://openalex.org/W2534271452","https://openalex.org/W2559092651","https://openalex.org/W2623663856","https://openalex.org/W2771176174","https://openalex.org/W2786084903","https://openalex.org/W2885022815","https://openalex.org/W2885332589","https://openalex.org/W2892120842","https://openalex.org/W2904378747","https://openalex.org/W2909883195","https://openalex.org/W2921651552","https://openalex.org/W2923068715","https://openalex.org/W2972919080","https://openalex.org/W2984450782","https://openalex.org/W3022376055","https://openalex.org/W3097325346","https://openalex.org/W3123519076","https://openalex.org/W3174611857","https://openalex.org/W3196972804","https://openalex.org/W3202815206","https://openalex.org/W6703491035","https://openalex.org/W6797889839"],"related_works":["https://openalex.org/W4387497383","https://openalex.org/W2948807893","https://openalex.org/W2778153218","https://openalex.org/W2748952813","https://openalex.org/W1531601525","https://openalex.org/W4391375266","https://openalex.org/W3031052312","https://openalex.org/W4389568370","https://openalex.org/W3032375762","https://openalex.org/W2078814861"],"abstract_inverted_index":{"Positron":[0],"emission":[1],"tomography":[2],"(PET)":[3],"with":[4,117,255,263],"<sup>18</sup>F-PM-PBB3":[5],"(<sup>18</sup>F-APN-1607,":[6],"<sup>18</sup>F-Florzolotau)":[7],"enables":[8],"high-contrast":[9],"detection":[10],"of":[11,84,102,121,142,222,281,284,291],"tau":[12,54,76,123,231,285],"depositions":[13],"in":[14,34,61,78,217,225,233,241,260,287],"various":[15],"neurodegenerative":[16,292],"dementias,":[17],"including":[18],"Alzheimer's":[19],"disease":[20],"(AD)":[21],"and":[22,104,146,159,164,180,201,204,211,219,235,251,265],"frontotemporal":[23],"lobar":[24],"degeneration":[25],"(FTLD).":[26],"A":[27],"simplified":[28],"method":[29,94],"for":[30,95,271],"quantifying":[31],"radioligand":[32,144,239],"binding":[33],"target":[35],"regions":[36,226],"is":[37,58],"to":[38,90,113,137,149,182,228],"employ":[39],"the":[40,47,50,79,82,143,207,279],"cerebellum":[41,51],"as":[42,275],"a":[43,110,118,134,214,288],"reference":[44,97,115,273],"(CB-ref)":[45],"on":[46,99],"assumption":[48],"that":[49],"has":[52],"minimal":[53],"pathologies.":[55],"This":[56],"procedure":[57],"typically":[59],"valid":[60],"AD,":[62],"while":[63],"FTLD":[64,168,261],"disorders":[65],"exemplified":[66],"by":[67,74,133,198,249],"progressive":[68],"supranuclear":[69],"palsy":[70],"(PSP)":[71],"are":[72],"characterized":[73],"occasional":[75],"accumulations":[77],"cerebellum,":[80],"hampering":[81],"application":[83],"CB-ref.":[85],"The":[86,269],"present":[87],"study":[88],"aimed":[89],"establish":[91],"an":[92,138],"optimal":[93],"defining":[96],"tissues":[98,274],"<sup>18</sup>F-PM-PBB3-PET":[100,150,282],"images":[101,171,196,254],"AD":[103,234],"non-AD":[105],"tauopathy":[106],"brains.":[107],"We":[108],"developed":[109],"new":[111],"algorithm":[112],"extract":[114],"voxels":[116,223],"low":[119],"likelihood":[120],"containing":[122],"deposits":[124],"from":[125,153],"gray":[126],"matter":[127,131],"(GM-ref)":[128],"or":[129],"white":[130],"(WM-ref)":[132],"bimodal":[135],"fit":[136],"individual,":[139],"voxel-wise":[140],"histogram":[141],"retentions":[145,240],"applied":[147],"it":[148],"data":[151],"obtained":[152],"age-matched":[154],"40":[155,162],"healthy":[156],"controls":[157],"(HCs)":[158],"23":[160],"CE,":[161],"PSP,":[163],"five":[165],"other":[166],"tau-positive":[167],"patients.":[169,237],"PET":[170],"acquired":[172],"at":[173],"90-110":[174],"min":[175],"after":[176],"injection":[177],"were":[178,220],"averaged":[179],"co-registered":[181],"corresponding":[183],"magnetic":[184],"resonance":[185],"imaging":[186],"space.":[187],"Subsequently,":[188],"we":[189],"generated":[190],"standardized":[191],"uptake":[192],"value":[193],"ratio":[194],"(SUVR)":[195],"estimated":[197],"CB-ref,":[199],"GM-ref":[200,210,246],"WM-ref,":[202],"respectively,":[203],"then":[205],"compared":[206],"diagnostic":[208],"performances.":[209],"WM-ref":[212,242],"covered":[213],"broad":[215],"area":[216],"HCs":[218],"free":[221],"located":[224],"known":[227],"bear":[229],"high":[230],"burdens":[232,286],"PSP":[236],"However,":[238],"exhibited":[243],"age-related":[244],"declines.":[245],"was":[247],"unaffected":[248],"aging":[250],"provided":[252],"SUVR":[253],"higher":[256],"contrast":[257],"than":[258],"CB-ref":[259],"patients":[262],"suspected":[264],"confirmed":[266],"corticobasal":[267],"degeneration.":[268],"methodology":[270],"determining":[272],"optimized":[276],"here":[277],"improves":[278],"accuracy":[280],"measurements":[283],"wide":[289],"range":[290],"illnesses.":[293]},"counts_by_year":[{"year":2025,"cited_by_count":11},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":1}],"updated_date":"2026-04-09T08:11:56.329763","created_date":"2022-11-30T00:00:00"}