{"id":"https://openalex.org/W2969657290","doi":"https://doi.org/10.1016/j.media.2019.101547","title":"Learning to detect lymphocytes in immunohistochemistry with deep learning","display_name":"Learning to detect lymphocytes in immunohistochemistry with deep learning","publication_year":2019,"publication_date":"2019-08-21","ids":{"openalex":"https://openalex.org/W2969657290","doi":"https://doi.org/10.1016/j.media.2019.101547","mag":"2969657290","pmid":"https://pubmed.ncbi.nlm.nih.gov/31476576"},"language":"en","primary_location":{"id":"doi:10.1016/j.media.2019.101547","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.media.2019.101547","pdf_url":"https://ars.els-cdn.com/content/image/1-s2.0-S1361841519300829-fx1_lrg.jpg","source":{"id":"https://openalex.org/S116571295","display_name":"Medical Image Analysis","issn_l":"1361-8415","issn":["1361-8415","1361-8423","1361-8431"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Image Analysis","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://ars.els-cdn.com/content/image/1-s2.0-S1361841519300829-fx1_lrg.jpg","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5076314803","display_name":"\u017baneta \u015awiderska-Chadaj","orcid":"https://orcid.org/0000-0003-2115-9822"},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]},{"id":"https://openalex.org/I2802849423","display_name":"University Medical Center","ror":"https://ror.org/036pt7h44","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2802849423"]},{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]},{"id":"https://openalex.org/I4210109357","display_name":"Radboud Institute for Molecular Life Sciences","ror":"https://ror.org/01yb10j39","country_code":"NL","type":"facility","lineage":["https://openalex.org/I145872427","https://openalex.org/I4210109357"]}],"countries":["NL","US"],"is_corresponding":true,"raw_author_name":"Zaneta Swiderska-Chadaj","raw_affiliation_strings":["Department of Pathology, Radboud University Medical Center, The Netherlands. Electronic address: zaneta.swiderska@radboudumc.nl","Department of Pathology, Radboud University Medical Center, The Netherlands"],"raw_orcid":"https://orcid.org/0000-0003-2115-9822","affiliations":[{"raw_affiliation_string":"Department of Pathology, Radboud University Medical Center, The Netherlands. Electronic address: zaneta.swiderska@radboudumc.nl","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802849423","https://openalex.org/I2802934949","https://openalex.org/I4210109357"]},{"raw_affiliation_string":"Department of Pathology, Radboud University Medical Center, The Netherlands","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062268913","display_name":"Hans Pinckaers","orcid":"https://orcid.org/0000-0002-7570-9300"},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]},{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Hans Pinckaers","raw_affiliation_strings":["Department of Pathology, Radboud University Medical Center, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Radboud University Medical Center, The Netherlands","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032516206","display_name":"Mart van Rijthoven","orcid":"https://orcid.org/0000-0003-3758-4348"},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]},{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Mart van Rijthoven","raw_affiliation_strings":["Department of Pathology, Radboud University Medical Center, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Radboud University Medical Center, The Netherlands","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009366591","display_name":"Maschenka Balkenhol","orcid":"https://orcid.org/0000-0001-9457-618X"},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]},{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Maschenka Balkenhol","raw_affiliation_strings":["Department of Pathology, Radboud University Medical Center, The Netherlands"],"raw_orcid":"https://orcid.org/0000-0001-9457-618X","affiliations":[{"raw_affiliation_string":"Department of Pathology, Radboud University Medical Center, The Netherlands","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108105891","display_name":"Margarita Melnikova","orcid":null},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]},{"id":"https://openalex.org/I204337017","display_name":"Aarhus University","ror":"https://ror.org/01aj84f44","country_code":"DK","type":"education","lineage":["https://openalex.org/I204337017"]},{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]},{"id":"https://openalex.org/I4210153757","display_name":"Regional Hospital Randers","ror":"https://ror.org/05n00ke18","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I4210153757"]}],"countries":["DK","NL"],"is_corresponding":false,"raw_author_name":"Margarita Melnikova","raw_affiliation_strings":["Department of Pathology, Radboud University Medical Center, The Netherlands; Department of Clinical Medicine, Aarhus University, Denmark; Institute of Pathology, Randers Regional Hospital, Denmark","Department of Clinical Medicine, Aarhus University, Denmark","Department of Pathology, Radboud University Medical Center, The Netherlands","Institute of Pathology, Randers Regional Hospital, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Radboud University Medical Center, The Netherlands; Department of Clinical Medicine, Aarhus University, Denmark; Institute of Pathology, Randers Regional Hospital, Denmark","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949","https://openalex.org/I4210153757"]},{"raw_affiliation_string":"Department of Clinical Medicine, Aarhus University, Denmark","institution_ids":["https://openalex.org/I204337017"]},{"raw_affiliation_string":"Department of Pathology, Radboud University Medical Center, The Netherlands","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949"]},{"raw_affiliation_string":"Institute of Pathology, Randers Regional Hospital, Denmark","institution_ids":["https://openalex.org/I4210153757"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058507207","display_name":"Oscar Geessink","orcid":"https://orcid.org/0000-0001-8114-3852"},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]},{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Oscar Geessink","raw_affiliation_strings":["Department of Pathology, Radboud University Medical Center, The Netherlands"],"raw_orcid":"https://orcid.org/0000-0001-8114-3852","affiliations":[{"raw_affiliation_string":"Department of Pathology, Radboud University Medical Center, The Netherlands","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047973057","display_name":"Quirine F. Manson","orcid":"https://orcid.org/0000-0001-7036-748X"},"institutions":[{"id":"https://openalex.org/I3018483916","display_name":"University Medical Center Utrecht","ror":"https://ror.org/0575yy874","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Quirine Manson","raw_affiliation_strings":["Department of Pathology, University Medical Center, Utrecht, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, University Medical Center, Utrecht, The Netherlands","institution_ids":["https://openalex.org/I3018483916"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009475462","display_name":"Mark E. Sherman","orcid":"https://orcid.org/0000-0002-9222-8808"},"institutions":[{"id":"https://openalex.org/I2801572250","display_name":"Jacksonville College","ror":"https://ror.org/03a9t7g49","country_code":"US","type":"education","lineage":["https://openalex.org/I2801572250"]},{"id":"https://openalex.org/I2802423016","display_name":"WinnMed","ror":"https://ror.org/02s47w807","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I2802423016"]},{"id":"https://openalex.org/I4210146710","display_name":"Mayo Clinic in Florida","ror":"https://ror.org/03zzw1w08","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210146710"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark Sherman","raw_affiliation_strings":["Mayo Clinic, Jacksonville, Florida, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mayo Clinic, Jacksonville, Florida, USA","institution_ids":["https://openalex.org/I2801572250","https://openalex.org/I2802423016","https://openalex.org/I4210146710"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033550609","display_name":"Ant\u00f3nio Pol\u00f3nia","orcid":"https://orcid.org/0000-0001-8312-1681"},"institutions":[{"id":"https://openalex.org/I182534213","display_name":"Universidade do Porto","ror":"https://ror.org/043pwc612","country_code":"PT","type":"education","lineage":["https://openalex.org/I182534213"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Antonio Polonia","raw_affiliation_strings":["Institute of Molecular Pathology and Immunology, University of Porto, Porto, Portugal"],"raw_orcid":"https://orcid.org/0000-0001-8312-1681","affiliations":[{"raw_affiliation_string":"Institute of Molecular Pathology and Immunology, University of Porto, Porto, Portugal","institution_ids":["https://openalex.org/I182534213"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101932256","display_name":"Jeremy Parry","orcid":"https://orcid.org/0000-0002-1688-4790"},"institutions":[{"id":"https://openalex.org/I2800728469","display_name":"Fiona Stanley Hospital","ror":"https://ror.org/027p0bm56","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2799506148","https://openalex.org/I2800728469","https://openalex.org/I2800882159","https://openalex.org/I4388446375","https://openalex.org/I4388482742"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Jeremy Parry","raw_affiliation_strings":["Fiona Stanley Hospital, Murdoch, Perth, Western Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fiona Stanley Hospital, Murdoch, Perth, Western Australia","institution_ids":["https://openalex.org/I2800728469"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031810108","display_name":"Mustapha Abubakar","orcid":"https://orcid.org/0000-0003-3728-6535"},"institutions":[{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4391012607","display_name":"Division of Cancer Epidemiology and Genetics","ror":"https://ror.org/00vkwep27","country_code":null,"type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mustapha Abubakar","raw_affiliation_strings":["Integrative Tumor Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Integrative Tumor Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, USA","institution_ids":["https://openalex.org/I4210140884","https://openalex.org/I4391012607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055697525","display_name":"Geert Litjens","orcid":"https://orcid.org/0000-0003-1554-1291"},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]},{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Geert Litjens","raw_affiliation_strings":["Department of Pathology, Radboud University Medical Center, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Radboud University Medical Center, The Netherlands","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081003438","display_name":"Jeroen van der Laak","orcid":"https://orcid.org/0000-0001-7982-0754"},"institutions":[{"id":"https://openalex.org/I102134673","display_name":"Link\u00f6ping University","ror":"https://ror.org/05ynxx418","country_code":"SE","type":"education","lineage":["https://openalex.org/I102134673"]},{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]},{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]}],"countries":["NL","SE"],"is_corresponding":false,"raw_author_name":"Jeroen van der Laak","raw_affiliation_strings":["Department of Pathology, Radboud University Medical Center, The Netherlands; Center for Medical Image Science and Visualization, Link\u00f6ping University, Link\u00f6ping, Sweden","Center for Medical Image Science and Visualization, Link\u00f6ping University, Link\u00f6ping, Sweden","Department of Pathology, Radboud University Medical Center, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Radboud University Medical Center, The Netherlands; Center for Medical Image Science and Visualization, Link\u00f6ping University, Link\u00f6ping, Sweden","institution_ids":["https://openalex.org/I102134673","https://openalex.org/I145872427","https://openalex.org/I2802934949"]},{"raw_affiliation_string":"Center for Medical Image Science and Visualization, Link\u00f6ping University, Link\u00f6ping, Sweden","institution_ids":["https://openalex.org/I102134673"]},{"raw_affiliation_string":"Department of Pathology, Radboud University Medical Center, The Netherlands","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5002905948","display_name":"Francesco Ciompi","orcid":"https://orcid.org/0000-0001-8327-9606"},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]},{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Francesco Ciompi","raw_affiliation_strings":["Department of Pathology, Radboud University Medical Center, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Radboud University Medical Center, The Netherlands","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949"]}]}],"institutions":[],"countries_distinct_count":6,"institutions_distinct_count":15,"corresponding_author_ids":["https://openalex.org/A5076314803"],"corresponding_institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802849423","https://openalex.org/I2802934949","https://openalex.org/I4210109357"],"apc_list":{"value":3970,"currency":"USD","value_usd":3970},"apc_paid":null,"fwci":11.88,"has_fulltext":true,"cited_by_count":170,"citation_normalized_percentile":{"value":0.98755271,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":100},"biblio":{"volume":"58","issue":null,"first_page":"101547","last_page":"101547"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12874","display_name":"Digital Imaging for Blood Diseases","score":0.9973999857902527,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10146","display_name":"Cervical Cancer and HPV Research","score":0.9855999946594238,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6476054191589355},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.584175705909729},{"id":"https://openalex.org/keywords/deep-learning","display_name":"Deep learning","score":0.5553869605064392},{"id":"https://openalex.org/keywords/immune-system","display_name":"Immune system","score":0.5080771446228027},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.3867376744747162},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.33762121200561523},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.2162884771823883},{"id":"https://openalex.org/keywords/immunology","display_name":"Immunology","score":0.1259479522705078}],"concepts":[{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6476054191589355},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.584175705909729},{"id":"https://openalex.org/C108583219","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep learning","level":2,"score":0.5553869605064392},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.5080771446228027},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.3867376744747162},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.33762121200561523},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2162884771823883},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.1259479522705078}],"mesh":[{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D003110","descriptor_name":"Colonic Neoplasms","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D003110","descriptor_name":"Colonic Neoplasms","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D003110","descriptor_name":"Colonic Neoplasms","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008214","descriptor_name":"Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008214","descriptor_name":"Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008214","descriptor_name":"Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009426","descriptor_name":"Netherlands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009426","descriptor_name":"Netherlands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009426","descriptor_name":"Netherlands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D016477","descriptor_name":"Artifacts","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016477","descriptor_name":"Artifacts","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016477","descriptor_name":"Artifacts","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066264","descriptor_name":"Datasets as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066264","descriptor_name":"Datasets as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066264","descriptor_name":"Datasets as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1016/j.media.2019.101547","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.media.2019.101547","pdf_url":"https://ars.els-cdn.com/content/image/1-s2.0-S1361841519300829-fx1_lrg.jpg","source":{"id":"https://openalex.org/S116571295","display_name":"Medical Image Analysis","issn_l":"1361-8415","issn":["1361-8415","1361-8423","1361-8431"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Image Analysis","raw_type":"journal-article"},{"id":"pmid:31476576","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31476576","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical image analysis","raw_type":null},{"id":"pmh:oai:pure.atira.dk:publications/ba70967a-eb31-4f6e-8d30-c064a483e8b2","is_oa":false,"landing_page_url":"https://pure.au.dk/portal/en/publications/ba70967a-eb31-4f6e-8d30-c064a483e8b2","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Swiderska-Chadaj, Z, Pinckaers, H, van Rijthoven, M, Balkenhol, M, Melnikova, M, Geessink, O, Manson, Q, Sherman, M, Polonia, A, Parry, J, Abubakar, M, Litjens, G, van der Laak, J & Ciompi, F 2019, 'Learning to detect lymphocytes in immunohistochemistry with deep learning', Medical Image Analysis, vol. 58, 101547. https://doi.org/10.1016/j.media.2019.101547","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:repository.ubn.ru.nl:2066/212611","is_oa":false,"landing_page_url":"https://hdl.handle.net/2066/212611","pdf_url":null,"source":{"id":"https://openalex.org/S4306401067","display_name":"Radboud Repository (Radboud University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I145872427","host_organization_name":"Radboud University Nijmegen","host_organization_lineage":["https://openalex.org/I145872427"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article / Letter to editor"},{"id":"pmh:ru:oai:repository.ubn.ru.nl:2066/212611","is_oa":true,"landing_page_url":"http://hdl.handle.net/2066/212611","pdf_url":null,"source":{"id":"https://openalex.org/S4306401843","display_name":"Data Archiving and Networked Services (DANS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1322597698","host_organization_name":"Royal Netherlands Academy of Arts and Sciences","host_organization_lineage":["https://openalex.org/I1322597698"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Medical Image Analysis, 58","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1016/j.media.2019.101547","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.media.2019.101547","pdf_url":"https://ars.els-cdn.com/content/image/1-s2.0-S1361841519300829-fx1_lrg.jpg","source":{"id":"https://openalex.org/S116571295","display_name":"Medical Image Analysis","issn_l":"1361-8415","issn":["1361-8415","1361-8423","1361-8431"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Image Analysis","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.6499999761581421}],"awards":[{"id":"https://openalex.org/G2802104974","display_name":null,"funder_award_id":"016.186.152","funder_id":"https://openalex.org/F4320321800","funder_display_name":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek"},{"id":"https://openalex.org/G434337789","display_name":null,"funder_award_id":"HORIZON2020","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G5113281195","display_name":"EXtreme-scale Analytics via Multimodal Ontology Discovery & Enhancement","funder_award_id":"825292","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"}],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320321800","display_name":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek","ror":"https://ror.org/04jsz6e67"},{"id":"https://openalex.org/F4320323698","display_name":"Radboud Universitair Medisch Centrum","ror":"https://ror.org/05wg1m734"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2969657290.pdf","grobid_xml":"https://content.openalex.org/works/W2969657290.grobid-xml"},"referenced_works_count":57,"referenced_works":["https://openalex.org/W168227540","https://openalex.org/W639708223","https://openalex.org/W1165382972","https://openalex.org/W1901129140","https://openalex.org/W1903029394","https://openalex.org/W1990602451","https://openalex.org/W2101327682","https://openalex.org/W2117692326","https://openalex.org/W2142300779","https://openalex.org/W2150290224","https://openalex.org/W2164777277","https://openalex.org/W2248620004","https://openalex.org/W2302088846","https://openalex.org/W2312404985","https://openalex.org/W2315626910","https://openalex.org/W2344654247","https://openalex.org/W2384495648","https://openalex.org/W2398921440","https://openalex.org/W2406638278","https://openalex.org/W2499316477","https://openalex.org/W2504150216","https://openalex.org/W2557738935","https://openalex.org/W2571530565","https://openalex.org/W2581082771","https://openalex.org/W2582414407","https://openalex.org/W2608119321","https://openalex.org/W2748619263","https://openalex.org/W2770980425","https://openalex.org/W2771794944","https://openalex.org/W2772677509","https://openalex.org/W2772723798","https://openalex.org/W2796347433","https://openalex.org/W2796409016","https://openalex.org/W2805886241","https://openalex.org/W2844479918","https://openalex.org/W2905003376","https://openalex.org/W2915297574","https://openalex.org/W2919115771","https://openalex.org/W2951433694","https://openalex.org/W2951548327","https://openalex.org/W2953106684","https://openalex.org/W2963037989","https://openalex.org/W2963542991","https://openalex.org/W4236965008","https://openalex.org/W4237107236","https://openalex.org/W4293584584","https://openalex.org/W4299545679","https://openalex.org/W4300718545","https://openalex.org/W4301409532","https://openalex.org/W6606896255","https://openalex.org/W6631782140","https://openalex.org/W6639824700","https://openalex.org/W6640054144","https://openalex.org/W6712450407","https://openalex.org/W6713723668","https://openalex.org/W6745760337","https://openalex.org/W6759009588"],"related_works":["https://openalex.org/W2731899572","https://openalex.org/W2961085424","https://openalex.org/W3215138031","https://openalex.org/W4306674287","https://openalex.org/W3009238340","https://openalex.org/W4360585206","https://openalex.org/W4321369474","https://openalex.org/W4285208911","https://openalex.org/W4387369504","https://openalex.org/W3082895349"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":12},{"year":2025,"cited_by_count":18},{"year":2024,"cited_by_count":34},{"year":2023,"cited_by_count":31},{"year":2022,"cited_by_count":34},{"year":2021,"cited_by_count":25},{"year":2020,"cited_by_count":14},{"year":2019,"cited_by_count":2}],"updated_date":"2026-08-04T08:18:43.703281","created_date":"2019-08-29T00:00:00"}