{"id":"https://openalex.org/W4410285457","doi":"https://doi.org/10.1016/j.compbiomed.2025.110248","title":"Exploring the diagnostic potential of EEG theta power and interhemispheric correlation of temporal lobe activities in Alzheimer\u2019s Disease through random forest analysis","display_name":"Exploring the diagnostic potential of EEG theta power and interhemispheric correlation of temporal lobe activities in Alzheimer\u2019s Disease through random forest analysis","publication_year":2025,"publication_date":"2025-05-12","ids":{"openalex":"https://openalex.org/W4410285457","doi":"https://doi.org/10.1016/j.compbiomed.2025.110248","pmid":"https://pubmed.ncbi.nlm.nih.gov/40359673"},"language":"en","primary_location":{"id":"doi:10.1016/j.compbiomed.2025.110248","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.compbiomed.2025.110248","pdf_url":null,"source":{"id":"https://openalex.org/S44278595","display_name":"Computers in Biology and Medicine","issn_l":"0010-4825","issn":["0010-4825","1879-0534"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computers in Biology and Medicine","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.compbiomed.2025.110248","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063484603","display_name":"A Lee","orcid":null},"institutions":[{"id":"https://openalex.org/I123900574","display_name":"Pohang University of Science and Technology","ror":"https://ror.org/04xysgw12","country_code":"KR","type":"education","lineage":["https://openalex.org/I123900574"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Ahhyun Lucy Lee","raw_affiliation_strings":["Department of Life Sciences, POSTECH, Pohang, Gyeongsangbukdo, 37673, Republic of Korea; Research Center, Lablup Inc., Seoul, 06161, Republic of Korea; Department of Brain and Cognitive Sciences, Seoul National University, Seoul, 08826, Republic of Korea. Electronic address: ahhyun724@postech.ac.kr"],"raw_orcid":"https://orcid.org/0009-0009-8850-9269","affiliations":[{"raw_affiliation_string":"Department of Life Sciences, POSTECH, Pohang, Gyeongsangbukdo, 37673, Republic of Korea; Research Center, Lablup Inc., Seoul, 06161, Republic of Korea; Department of Brain and Cognitive Sciences, Seoul National University, Seoul, 08826, Republic of Korea. Electronic address: ahhyun724@postech.ac.kr","institution_ids":["https://openalex.org/I123900574"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103984788","display_name":"Eunjin Hwang","orcid":null},"institutions":[{"id":"https://openalex.org/I4210159093","display_name":"Jeil Pharmaceutical (South Korea)","ror":"https://ror.org/04z9hzj86","country_code":"KR","type":"company","lineage":["https://openalex.org/I4210159093"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Eunjin Hwang","raw_affiliation_strings":["Research Center, Lablup Inc., Seoul, 06161, Republic of Korea. Electronic address: ejhwang@lablup.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Center, Lablup Inc., Seoul, 06161, Republic of Korea. Electronic address: ejhwang@lablup.com","institution_ids":["https://openalex.org/I4210159093"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5084639093","display_name":"Jeongeun Hwang","orcid":"https://orcid.org/0000-0002-5821-5405"},"institutions":[{"id":"https://openalex.org/I24541011","display_name":"Soonchunhyang University","ror":"https://ror.org/03qjsrb10","country_code":"KR","type":"education","lineage":["https://openalex.org/I24541011"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Jeongeun Hwang","raw_affiliation_strings":["Department of Medical IT Engineering, College of Software Convergence, Soonchunhyang University, Asan, Chungcheongnam-do, 31538, Republic of Korea. Electronic address: hwangje02@sch.ac.kr"],"raw_orcid":"https://orcid.org/0000-0002-5821-5405","affiliations":[{"raw_affiliation_string":"Department of Medical IT Engineering, College of Software Convergence, Soonchunhyang University, Asan, Chungcheongnam-do, 31538, Republic of Korea. Electronic address: hwangje02@sch.ac.kr","institution_ids":["https://openalex.org/I24541011"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5084639093"],"corresponding_institution_ids":["https://openalex.org/I24541011"],"apc_list":{"value":2610,"currency":"USD","value_usd":2610},"apc_paid":{"value":2610,"currency":"USD","value_usd":2610},"fwci":2.3116,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.87311738,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":97},"biblio":{"volume":"192","issue":"Pt B","first_page":"110248","last_page":"110248"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":0.7110000252723694,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":0.7110000252723694,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.11599999666213989,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.09780000150203705,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/electroencephalography","display_name":"Electroencephalography","score":0.7537919282913208},{"id":"https://openalex.org/keywords/temporal-lobe","display_name":"Temporal lobe","score":0.5793685913085938},{"id":"https://openalex.org/keywords/correlation","display_name":"Correlation","score":0.548448920249939},{"id":"https://openalex.org/keywords/frontal-lobe","display_name":"Frontal lobe","score":0.4786166548728943},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.45388513803482056},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.4352942705154419},{"id":"https://openalex.org/keywords/audiology","display_name":"Audiology","score":0.43200933933258057},{"id":"https://openalex.org/keywords/random-forest","display_name":"Random forest","score":0.4213167428970337},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.27152910828590393},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.24273726344108582},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.22615015506744385},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.18864065408706665},{"id":"https://openalex.org/keywords/epilepsy","display_name":"Epilepsy","score":0.15065813064575195}],"concepts":[{"id":"https://openalex.org/C522805319","wikidata":"https://www.wikidata.org/wiki/Q179965","display_name":"Electroencephalography","level":2,"score":0.7537919282913208},{"id":"https://openalex.org/C2781099131","wikidata":"https://www.wikidata.org/wiki/Q744385","display_name":"Temporal lobe","level":3,"score":0.5793685913085938},{"id":"https://openalex.org/C117220453","wikidata":"https://www.wikidata.org/wiki/Q5172842","display_name":"Correlation","level":2,"score":0.548448920249939},{"id":"https://openalex.org/C2777127467","wikidata":"https://www.wikidata.org/wiki/Q749520","display_name":"Frontal lobe","level":2,"score":0.4786166548728943},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.45388513803482056},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.4352942705154419},{"id":"https://openalex.org/C548259974","wikidata":"https://www.wikidata.org/wiki/Q569965","display_name":"Audiology","level":1,"score":0.43200933933258057},{"id":"https://openalex.org/C169258074","wikidata":"https://www.wikidata.org/wiki/Q245748","display_name":"Random forest","level":2,"score":0.4213167428970337},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.27152910828590393},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.24273726344108582},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.22615015506744385},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.18864065408706665},{"id":"https://openalex.org/C2778186239","wikidata":"https://www.wikidata.org/wiki/Q41571","display_name":"Epilepsy","level":2,"score":0.15065813064575195},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000093743","descriptor_name":"Random Forest","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000093743","descriptor_name":"Random Forest","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000093743","descriptor_name":"Random Forest","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D000544","descriptor_name":"Alzheimer Disease","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012815","descriptor_name":"Signal Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012815","descriptor_name":"Signal Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012815","descriptor_name":"Signal Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013702","descriptor_name":"Temporal Lobe","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D013702","descriptor_name":"Temporal Lobe","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D013702","descriptor_name":"Temporal Lobe","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D013826","descriptor_name":"Theta Rhythm","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D013826","descriptor_name":"Theta Rhythm","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D013826","descriptor_name":"Theta Rhythm","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.compbiomed.2025.110248","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.compbiomed.2025.110248","pdf_url":null,"source":{"id":"https://openalex.org/S44278595","display_name":"Computers in Biology and Medicine","issn_l":"0010-4825","issn":["0010-4825","1879-0534"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computers in Biology and Medicine","raw_type":"journal-article"},{"id":"pmid:40359673","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40359673","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computers in biology and medicine","raw_type":null}],"best_oa_location":{"id":"doi:10.1016/j.compbiomed.2025.110248","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.compbiomed.2025.110248","pdf_url":null,"source":{"id":"https://openalex.org/S44278595","display_name":"Computers in Biology and Medicine","issn_l":"0010-4825","issn":["0010-4825","1879-0534"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computers in Biology and Medicine","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G4936883998","display_name":null,"funder_award_id":"20240557","funder_id":"https://openalex.org/F4320321301","funder_display_name":"Soonchunhyang University"}],"funders":[{"id":"https://openalex.org/F4320321301","display_name":"Soonchunhyang University","ror":"https://ror.org/03qjsrb10"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":85,"referenced_works":["https://openalex.org/W317957491","https://openalex.org/W790230710","https://openalex.org/W1929734874","https://openalex.org/W1956468623","https://openalex.org/W1971562659","https://openalex.org/W1986526455","https://openalex.org/W1993812357","https://openalex.org/W2000446844","https://openalex.org/W2003689160","https://openalex.org/W2015153982","https://openalex.org/W2044488773","https://openalex.org/W2051489981","https://openalex.org/W2052742260","https://openalex.org/W2062989416","https://openalex.org/W2064043796","https://openalex.org/W2065338300","https://openalex.org/W2101234009","https://openalex.org/W2106822551","https://openalex.org/W2110065044","https://openalex.org/W2110444396","https://openalex.org/W2115017507","https://openalex.org/W2115069519","https://openalex.org/W2118320651","https://openalex.org/W2128228199","https://openalex.org/W2129497119","https://openalex.org/W2143461767","https://openalex.org/W2151393950","https://openalex.org/W2158592797","https://openalex.org/W2263173985","https://openalex.org/W2334028018","https://openalex.org/W2419223092","https://openalex.org/W2510477473","https://openalex.org/W2551054676","https://openalex.org/W2560234750","https://openalex.org/W2562313306","https://openalex.org/W2575359420","https://openalex.org/W2582524520","https://openalex.org/W2744681430","https://openalex.org/W2794124526","https://openalex.org/W2801948581","https://openalex.org/W2838070964","https://openalex.org/W2895258853","https://openalex.org/W2903334206","https://openalex.org/W2996722826","https://openalex.org/W3003257820","https://openalex.org/W3011044243","https://openalex.org/W3014686944","https://openalex.org/W3020177819","https://openalex.org/W3035965352","https://openalex.org/W3041023372","https://openalex.org/W3085152913","https://openalex.org/W3086032303","https://openalex.org/W3099878876","https://openalex.org/W3112948680","https://openalex.org/W3115292829","https://openalex.org/W3118587845","https://openalex.org/W3133698909","https://openalex.org/W3159837519","https://openalex.org/W3171637117","https://openalex.org/W3202208822","https://openalex.org/W3205824203","https://openalex.org/W4207036521","https://openalex.org/W4210468844","https://openalex.org/W4210568196","https://openalex.org/W4211156109","https://openalex.org/W4280556554","https://openalex.org/W4281972751","https://openalex.org/W4283528092","https://openalex.org/W4294266493","https://openalex.org/W4372782057","https://openalex.org/W4377157636","https://openalex.org/W4385892549","https://openalex.org/W4386142022","https://openalex.org/W4387350643","https://openalex.org/W4391675458","https://openalex.org/W4392362094","https://openalex.org/W4400089962","https://openalex.org/W6601579311","https://openalex.org/W6634556219","https://openalex.org/W6666427799","https://openalex.org/W6675354045","https://openalex.org/W6676186243","https://openalex.org/W6683725319","https://openalex.org/W6802739831","https://openalex.org/W6839960444"],"related_works":["https://openalex.org/W3193043704","https://openalex.org/W4386259002","https://openalex.org/W1546989560","https://openalex.org/W3171520305","https://openalex.org/W2922348724","https://openalex.org/W1924178503","https://openalex.org/W200322357","https://openalex.org/W3135126032","https://openalex.org/W2236178445","https://openalex.org/W2010456997"],"abstract_inverted_index":{"BACKGROUND:":[0],"Considering":[1],"the":[2,9,13,65,73,97,189,225,229,234,251,270,292,317,328,337,345,365],"prevalence":[3],"of":[4,16,76,102,152,158,263,294,319,339,347,357,367],"Alzheimer's":[5],"Disease":[6],"(AD)":[7],"among":[8],"aging":[10],"population":[11],"and":[12,94,105,115,133,137,147,191,260,310,336,350],"limited":[14],"means":[15],"treatment,":[17],"early":[18],"detection":[19],"emerges":[20],"as":[21,156,269],"a":[22,30,61,142],"crucial":[23,62],"focus":[24],"area":[25],"whereas":[26,206],"electroencephalography":[27],"(EEG)":[28],"provides":[29],"promising":[31],"diagnostic":[32,44,74],"tool.":[33],"To":[34],"date,":[35],"several":[36],"studies":[37],"indicated":[38],"EEG":[39,77,90,100,358],"dataset-based":[40],"models":[41,241,298,305],"sporting":[42],"high":[43,322,333],"power":[45,93,136,166,196,208],"in":[46,64,194,211,216,224,254,313,353,360],"distinguishing":[47,79,275],"patients":[48,80,107,130,201,217,276,361],"with":[49,81,108,131,202,218,242,277,299,332,362],"AD":[50,82,109,132,203,219,278],"from":[51,83,96,279],"healthy":[52],"controls":[53],"(HC).":[54],"However,":[55],"exploration":[56],"into":[57,372],"which":[58],"features":[59,125,159,273,290,296],"play":[60],"role":[63],"diagnosis":[66],"remains":[67],"limited.":[68],"METHODS:":[69],"This":[70,342],"study":[71],"investigates":[72],"capabilities":[75],"for":[78,200,233,274],"HCs":[84,104],"through":[85],"random":[86,143],"forest":[87,144],"classification":[88],"on":[89,250,282],"features.":[91],"Band":[92,135],"cross-correlation":[95,138,172,223,235,262,285],"resting":[98],"state":[99],"dataset":[101,286,330],"22":[103],"160":[106],"were":[110,139,197],"calculated":[111],"using":[112,141],"Welch's":[113,119],"periodogram":[114],"Pearson's":[116],"correlation,":[117],"respectively.":[118],"t-test":[120],"was":[121,174,214],"applied":[122],"to":[123,327],"identify":[124],"demonstrating":[126],"significant":[127],"differences":[128],"between":[129,188],"HCs.":[134,280],"analyzed":[140],"classifier":[145],"(RFC)":[146],"feature-importance":[148,247],"analysis.":[149],"The":[150,304],"importance":[151],"feature":[153],"categories,":[154],"defined":[155],"subsets":[157],"grouped":[160],"by":[161,176,246,288],"frequency":[162],"bands":[163],"(for":[164,171],"band":[165],"features)":[167],"or":[168],"brain":[169],"regions":[170,213],"features),":[173],"quantified":[175],"calculating":[177],"their":[178],"average":[179],"occurrence":[180],"across":[181,297],"all":[182,212],"hyperparameter":[183,301],"configurations.":[184],"RESULT:":[185],"Distinct":[186],"patterns":[187],"eyes-closed":[190],"eyes-open":[192],"conditions":[193],"alpha":[195],"not":[198],"observed":[199],"(vs.":[204,220],"HC),":[205],"theta":[207],"(4-8":[209],"Hz)":[210],"higher":[215],"HC)(p<0.05).":[221],"Interhemispheric":[222],"temporal":[226,267],"lobes":[227],"exhibited":[228],"most":[230,271],"distinguishable":[231],"distribution":[232],"dataset.":[236],"An":[237],"RFC,":[238],"exploring":[239],"512":[240],"varied":[243],"hyperparameters":[244],"followed":[245],"analysis":[248],"based":[249],"mean":[252],"decrease":[253],"impurity,":[255],"highlighted":[256],"\"theta":[257],"relative":[258],"power\"":[259],"\"interhemispheric":[261],"channel":[264],"pairs":[265],"including":[266],"channels\"":[268],"important":[272,289,295],"RFC":[281],"theta-band":[283],"filtered":[284],"informed":[287],"demonstrated":[291],"robustness":[293],"different":[300],"settings.":[302],"DISCUSSION:":[303],"achieved":[306],"over":[307],"97%":[308],"accuracy":[309,323],"100%":[311],"recall":[312],"test":[314],"sets,":[315],"although":[316],"interpretation":[318],"this":[320],"extraordinarily":[321],"warrants":[324],"caution":[325],"due":[326],"small":[329],"size":[331],"data":[334],"imbalance":[335],"absence":[338],"external":[340],"validation.":[341],"methodology":[343],"demonstrates":[344],"efficacy":[346],"EEG-based":[348],"metrics":[349],"machine":[351,369],"learning":[352,370],"improving":[354],"our":[355],"understanding":[356],"characteristics":[359],"AD,":[363],"emphasizing":[364],"potential":[366],"integrating":[368],"techniques":[371],"clinical":[373],"practices.":[374]},"counts_by_year":[{"year":2025,"cited_by_count":3}],"updated_date":"2026-07-22T07:51:19.307946","created_date":"2025-10-10T00:00:00"}