{"id":"https://openalex.org/W2092798218","doi":"https://doi.org/10.1016/s1672-0229(11)60023-5","title":"Computational Identification of Sweet Wormwood (<i>Artemisia Annua</i>) microRNA and Their mRNA Targets","display_name":"Computational Identification of Sweet Wormwood (<i>Artemisia Annua</i>) microRNA and Their mRNA Targets","publication_year":2011,"publication_date":"2011-12-01","ids":{"openalex":"https://openalex.org/W2092798218","doi":"https://doi.org/10.1016/s1672-0229(11)60023-5","mag":"2092798218","pmid":"https://pubmed.ncbi.nlm.nih.gov/22289476"},"language":"en","primary_location":{"id":"doi:10.1016/s1672-0229(11)60023-5","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s1672-0229(11)60023-5","pdf_url":null,"source":{"id":"https://openalex.org/S155547894","display_name":"Genomics Proteomics & Bioinformatics","issn_l":"1672-0229","issn":["1672-0229","2210-3244"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genomics, Proteomics &amp; Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1016/s1672-0229(11)60023-5","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5024127939","display_name":"Alok Pani","orcid":null},"institutions":[{"id":"https://openalex.org/I13567498","display_name":"Odisha University of Agriculture and Technology","ror":"https://ror.org/03tg0z446","country_code":"IN","type":"education","lineage":["https://openalex.org/I13567498"]},{"id":"https://openalex.org/I67357951","display_name":"KIIT University","ror":"https://ror.org/00k8zt527","country_code":"IN","type":"education","lineage":["https://openalex.org/I67357951"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Alok Pani","raw_affiliation_strings":["Kalinga Institute of Industrial Technology (KIIT) University , , Bhubaneswar, Odisha, 751024 , India","School of Biotechnology , , Bhubaneswar, Odisha, 751024 , India","School of Biotechnology; Kalinga Institute of Industrial Technology (KIIT) University; Bhubaneswar Odisha 751024 India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kalinga Institute of Industrial Technology (KIIT) University , , Bhubaneswar, Odisha, 751024 , India","institution_ids":["https://openalex.org/I67357951"]},{"raw_affiliation_string":"School of Biotechnology , , Bhubaneswar, Odisha, 751024 , India","institution_ids":["https://openalex.org/I13567498"]},{"raw_affiliation_string":"School of Biotechnology; Kalinga Institute of Industrial Technology (KIIT) University; Bhubaneswar Odisha 751024 India","institution_ids":["https://openalex.org/I67357951"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035961875","display_name":"Rajani Kanta Mahapatra","orcid":null},"institutions":[{"id":"https://openalex.org/I112754052","display_name":"Sambalpur University","ror":"https://ror.org/04s222234","country_code":"IN","type":"education","lineage":["https://openalex.org/I112754052"]},{"id":"https://openalex.org/I13567498","display_name":"Odisha University of Agriculture and Technology","ror":"https://ror.org/03tg0z446","country_code":"IN","type":"education","lineage":["https://openalex.org/I13567498"]},{"id":"https://openalex.org/I185065464","display_name":"Veer Surendra Sai University of Technology","ror":"https://ror.org/02yghbg68","country_code":"IN","type":"education","lineage":["https://openalex.org/I185065464"]},{"id":"https://openalex.org/I67357951","display_name":"KIIT University","ror":"https://ror.org/00k8zt527","country_code":"IN","type":"education","lineage":["https://openalex.org/I67357951"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Rajani Kanta Mahapatra","raw_affiliation_strings":["Kalinga Institute of Industrial Technology (KIIT) University , , Bhubaneswar, Odisha, 751024 , India","Sambalpur University , , Burla, Odisha, 768019 , India","School of Biotechnology , , Bhubaneswar, Odisha, 751024 , India","School of Life Sciences , , Burla, Odisha, 768019 , India","School of Biotechnology, Kalinga Institute of Industrial Technology (KIIT) University, Bhubaneswar, Odisha 751024, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kalinga Institute of Industrial Technology (KIIT) University , , Bhubaneswar, Odisha, 751024 , India","institution_ids":["https://openalex.org/I67357951"]},{"raw_affiliation_string":"Sambalpur University , , Burla, Odisha, 768019 , India","institution_ids":["https://openalex.org/I112754052"]},{"raw_affiliation_string":"School of Biotechnology , , Bhubaneswar, Odisha, 751024 , India","institution_ids":["https://openalex.org/I13567498"]},{"raw_affiliation_string":"School of Life Sciences , , Burla, Odisha, 768019 , India","institution_ids":["https://openalex.org/I185065464"]},{"raw_affiliation_string":"School of Biotechnology, Kalinga Institute of Industrial Technology (KIIT) University, Bhubaneswar, Odisha 751024, India","institution_ids":["https://openalex.org/I67357951"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103876717","display_name":"Niranjan Behera","orcid":null},"institutions":[{"id":"https://openalex.org/I112754052","display_name":"Sambalpur University","ror":"https://ror.org/04s222234","country_code":"IN","type":"education","lineage":["https://openalex.org/I112754052"]},{"id":"https://openalex.org/I185065464","display_name":"Veer Surendra Sai University of Technology","ror":"https://ror.org/02yghbg68","country_code":"IN","type":"education","lineage":["https://openalex.org/I185065464"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Niranjan Behera","raw_affiliation_strings":["Sambalpur University , , Burla, Odisha, 768019 , India","School of Life Sciences , , Burla, Odisha, 768019 , India","School of Life Sciences, Sambalpur University, Burla, Odisha-768019, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sambalpur University , , Burla, Odisha, 768019 , India","institution_ids":["https://openalex.org/I112754052"]},{"raw_affiliation_string":"School of Life Sciences , , Burla, Odisha, 768019 , India","institution_ids":["https://openalex.org/I185065464"]},{"raw_affiliation_string":"School of Life Sciences, Sambalpur University, Burla, Odisha-768019, India","institution_ids":["https://openalex.org/I112754052"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5050368436","display_name":"Pradeep Kumar Naik","orcid":"https://orcid.org/0000-0001-7044-2427"},"institutions":[{"id":"https://openalex.org/I153954893","display_name":"Jaypee University of Information Technology","ror":"https://ror.org/00hshrf16","country_code":"IN","type":"education","lineage":["https://openalex.org/I153954893"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Pradeep Kumar Naik","raw_affiliation_strings":["Department of Biotechnology & Bioinformatics , , Solan, Himachal Pradesh, 173215 , India","Jaypee University of Information Technology , , Solan, Himachal Pradesh, 173215 , India","Department of Biotechnology & Bioinformatics, Jaypee University of Information Technology, Solan, Himachal Pradesh 173215, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biotechnology & Bioinformatics , , Solan, Himachal Pradesh, 173215 , India","institution_ids":["https://openalex.org/I153954893"]},{"raw_affiliation_string":"Jaypee University of Information Technology , , Solan, Himachal Pradesh, 173215 , India","institution_ids":["https://openalex.org/I153954893"]},{"raw_affiliation_string":"Department of Biotechnology & Bioinformatics, Jaypee University of Information Technology, Solan, Himachal Pradesh 173215, India","institution_ids":["https://openalex.org/I153954893"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5035961875"],"corresponding_institution_ids":["https://openalex.org/I112754052","https://openalex.org/I13567498","https://openalex.org/I185065464","https://openalex.org/I67357951"],"apc_list":{"value":3500,"currency":"USD","value_usd":3500},"apc_paid":{"value":3500,"currency":"USD","value_usd":3500},"fwci":0.9311,"has_fulltext":false,"cited_by_count":44,"citation_normalized_percentile":{"value":0.740286,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"9","issue":"6","first_page":"200","last_page":"210"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11882","display_name":"Plant biochemistry and biosynthesis","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11882","display_name":"Plant biochemistry and biosynthesis","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11966","display_name":"Silk-based biomaterials and applications","score":0.9855999946594238,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10184","display_name":"Plant Molecular Biology Research","score":0.984000027179718,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/artemisia-annua","display_name":"Artemisia annua","score":0.9604736566543579},{"id":"https://openalex.org/keywords/artemisinin","display_name":"Artemisinin","score":0.9081318378448486},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.705502986907959},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.6035085916519165},{"id":"https://openalex.org/keywords/farnesyl-pyrophosphate","display_name":"Farnesyl pyrophosphate","score":0.5910487174987793},{"id":"https://openalex.org/keywords/cytochrome-p450","display_name":"Cytochrome P450","score":0.4992516040802002},{"id":"https://openalex.org/keywords/in-silico","display_name":"In silico","score":0.49555981159210205},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4307026267051697},{"id":"https://openalex.org/keywords/microrna","display_name":"microRNA","score":0.43051862716674805},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.32360801100730896},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.31500953435897827},{"id":"https://openalex.org/keywords/atp-synthase","display_name":"ATP synthase","score":0.30342796444892883},{"id":"https://openalex.org/keywords/plasmodium-falciparum","display_name":"Plasmodium falciparum","score":0.21839362382888794},{"id":"https://openalex.org/keywords/enzyme","display_name":"Enzyme","score":0.20072072744369507},{"id":"https://openalex.org/keywords/malaria","display_name":"Malaria","score":0.10094195604324341}],"concepts":[{"id":"https://openalex.org/C2779691961","wikidata":"https://www.wikidata.org/wiki/Q1308044","display_name":"Artemisia annua","level":5,"score":0.9604736566543579},{"id":"https://openalex.org/C2776120307","wikidata":"https://www.wikidata.org/wiki/Q426921","display_name":"Artemisinin","level":4,"score":0.9081318378448486},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.705502986907959},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.6035085916519165},{"id":"https://openalex.org/C2776990775","wikidata":"https://www.wikidata.org/wiki/Q2699676","display_name":"Farnesyl pyrophosphate","level":4,"score":0.5910487174987793},{"id":"https://openalex.org/C526171541","wikidata":"https://www.wikidata.org/wiki/Q407693","display_name":"Cytochrome P450","level":3,"score":0.4992516040802002},{"id":"https://openalex.org/C2775905019","wikidata":"https://www.wikidata.org/wiki/Q192572","display_name":"In silico","level":3,"score":0.49555981159210205},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4307026267051697},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.43051862716674805},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.32360801100730896},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.31500953435897827},{"id":"https://openalex.org/C112243037","wikidata":"https://www.wikidata.org/wiki/Q22327117","display_name":"ATP synthase","level":3,"score":0.30342796444892883},{"id":"https://openalex.org/C2778371730","wikidata":"https://www.wikidata.org/wiki/Q311383","display_name":"Plasmodium falciparum","level":3,"score":0.21839362382888794},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.20072072744369507},{"id":"https://openalex.org/C2778048844","wikidata":"https://www.wikidata.org/wiki/Q12156","display_name":"Malaria","level":2,"score":0.10094195604324341},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D006903","descriptor_name":"Hydroxymethylglutaryl CoA Reductases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006903","descriptor_name":"Hydroxymethylglutaryl CoA Reductases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006903","descriptor_name":"Hydroxymethylglutaryl CoA Reductases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006903","descriptor_name":"Hydroxymethylglutaryl CoA Reductases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006903","descriptor_name":"Hydroxymethylglutaryl CoA Reductases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006903","descriptor_name":"Hydroxymethylglutaryl CoA Reductases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011106","descriptor_name":"Polyisoprenyl Phosphates","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011106","descriptor_name":"Polyisoprenyl Phosphates","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011106","descriptor_name":"Polyisoprenyl Phosphates","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012717","descriptor_name":"Sesquiterpenes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012717","descriptor_name":"Sesquiterpenes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012717","descriptor_name":"Sesquiterpenes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018076","descriptor_name":"DNA, Complementary","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018076","descriptor_name":"DNA, Complementary","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018076","descriptor_name":"DNA, Complementary","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018076","descriptor_name":"DNA, Complementary","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018076","descriptor_name":"DNA, Complementary","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018076","descriptor_name":"DNA, Complementary","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020224","descriptor_name":"Expressed Sequence Tags","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020224","descriptor_name":"Expressed Sequence Tags","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020224","descriptor_name":"Expressed Sequence Tags","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D025782","descriptor_name":"Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D025782","descriptor_name":"Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D025782","descriptor_name":"Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D025782","descriptor_name":"Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D025782","descriptor_name":"Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D025782","descriptor_name":"Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D031172","descriptor_name":"Artemisia annua","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D031172","descriptor_name":"Artemisia annua","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D031172","descriptor_name":"Artemisia annua","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D031172","descriptor_name":"Artemisia annua","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D031172","descriptor_name":"Artemisia annua","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D031172","descriptor_name":"Artemisia annua","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D031172","descriptor_name":"Artemisia annua","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D031172","descriptor_name":"Artemisia annua","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D031172","descriptor_name":"Artemisia annua","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D037621","descriptor_name":"Artemisinins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D037621","descriptor_name":"Artemisinins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D037621","descriptor_name":"Artemisinins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/s1672-0229(11)60023-5","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s1672-0229(11)60023-5","pdf_url":null,"source":{"id":"https://openalex.org/S155547894","display_name":"Genomics Proteomics & Bioinformatics","issn_l":"1672-0229","issn":["1672-0229","2210-3244"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genomics, Proteomics &amp; Bioinformatics","raw_type":"journal-article"},{"id":"pmid:22289476","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22289476","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genomics, proteomics & bioinformatics","raw_type":null},{"id":"pmh:oai:europepmc.org:4016528","is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5054163","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1016/s1672-0229(11)60023-5","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s1672-0229(11)60023-5","pdf_url":null,"source":{"id":"https://openalex.org/S155547894","display_name":"Genomics Proteomics & Bioinformatics","issn_l":"1672-0229","issn":["1672-0229","2210-3244"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genomics, Proteomics &amp; Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.699999988079071,"display_name":"Good health and well-being"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320331003","display_name":"Kalinga Institute of Industrial Technology","ror":"https://ror.org/00k8zt527"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":57,"referenced_works":["https://openalex.org/W144423133","https://openalex.org/W1967231259","https://openalex.org/W1969962785","https://openalex.org/W1976909997","https://openalex.org/W1988392160","https://openalex.org/W1992324215","https://openalex.org/W1992568358","https://openalex.org/W1994960170","https://openalex.org/W1995637306","https://openalex.org/W2014812831","https://openalex.org/W2019345938","https://openalex.org/W2023533798","https://openalex.org/W2025007124","https://openalex.org/W2029346162","https://openalex.org/W2043356893","https://openalex.org/W2047056824","https://openalex.org/W2047543068","https://openalex.org/W2049065350","https://openalex.org/W2051728363","https://openalex.org/W2053330542","https://openalex.org/W2053915285","https://openalex.org/W2057606871","https://openalex.org/W2059645638","https://openalex.org/W2060664866","https://openalex.org/W2064909918","https://openalex.org/W2070571588","https://openalex.org/W2072703437","https://openalex.org/W2081747395","https://openalex.org/W2087821308","https://openalex.org/W2088578964","https://openalex.org/W2094448442","https://openalex.org/W2096481443","https://openalex.org/W2097457822","https://openalex.org/W2098184601","https://openalex.org/W2099485284","https://openalex.org/W2103291173","https://openalex.org/W2112192177","https://openalex.org/W2133609306","https://openalex.org/W2139582953","https://openalex.org/W2140415861","https://openalex.org/W2149202606","https://openalex.org/W2150202616","https://openalex.org/W2152038789","https://openalex.org/W2152419282","https://openalex.org/W2152443621","https://openalex.org/W2157039533","https://openalex.org/W2157979318","https://openalex.org/W2158661852","https://openalex.org/W2162170048","https://openalex.org/W2168911096","https://openalex.org/W2231135105","https://openalex.org/W2788073857","https://openalex.org/W3122690812","https://openalex.org/W4233163680","https://openalex.org/W4249607862","https://openalex.org/W6654238886","https://openalex.org/W6682079381"],"related_works":["https://openalex.org/W2037209505","https://openalex.org/W3140940931","https://openalex.org/W2886721652","https://openalex.org/W2393195802","https://openalex.org/W2039894471","https://openalex.org/W3149303686","https://openalex.org/W2228665180","https://openalex.org/W2077381490","https://openalex.org/W3025705671","https://openalex.org/W3149344166"],"abstract_inverted_index":{"Despite":[0],"its":[1,35],"efficacy":[2],"against":[3,75],"malaria,":[4],"the":[5,20,23,29,106,170,174,196],"relatively":[6],"low":[7],"yield":[8],"(0.01%-0.8%)":[9],"of":[10,22,28,32,81,97,169,199],"artemisinin":[11,33,47,132,189,200],"in":[12,59,92,118,131,159,176,188,202],"Artemisia":[13],"annua":[14,83],"is":[15,43,157,173],"a":[16,150],"serious":[17],"limitation":[18],"to":[19,45,84,105,179,194],"commercialization":[21],"drug.":[24],"A":[25,95],"better":[26],"understanding":[27],"biosynthetic":[30],"pathway":[31],"and":[34,40,73,89,108,145,162],"regulation":[36,198],"by":[37],"both":[38],"exogenous":[39],"endogenous":[41],"factors":[42],"essential":[44],"improve":[46],"yield.":[48],"Increasing":[49],"evidence":[50],"has":[51],"shown":[52],"that":[53,127,181],"microRNAs":[54],"(miRNAs)":[55],"play":[56,128],"multiple":[57],"roles":[58,130],"various":[60],"biological":[61],"processes.":[62],"In":[63,148],"this":[64,119],"study,":[65],"we":[66],"used":[67],"previously":[68],"known":[69],"miRNAs":[70,88,100,182],"from":[71],"Arabidopsis":[72],"rice":[74],"expressed":[76],"sequence":[77],"tag":[78],"(EST)":[79],"database":[80],"A.":[82,93,203],"search":[85],"for":[86,153],"potential":[87,99,113],"their":[90],"targets":[91],"annua.":[94,204],"total":[96],"six":[98],"were":[101,116],"predicted,":[102],"which":[103,156,191],"belong":[104],"miR414":[107],"miR1310":[109],"families.":[110],"Furthermore,":[111],"eight":[112],"target":[114,183],"genes":[115,124,184],"identified":[117],"species.":[120],"Among":[121],"them,":[122],"seven":[123],"encode":[125],"proteins":[126],"important":[129],"biosynthesis,":[133,190],"including":[134],"HMG-CoA":[135],"reductase":[136],"(HMGR),":[137],"amorpha-4,11-diene":[138],"synthase":[139,143],"(ADS),":[140],"farnesyl":[141],"pyrophosphate":[142],"(FPS)":[144],"cytochrome":[146],"P450.":[147],"addition,":[149],"gene":[151],"coding":[152],"putative":[154],"AINTEGUMENTA,":[155],"involved":[158,187],"signal":[160],"transduction":[161],"development,":[163],"was":[164],"also":[165],"predicted":[166],"as":[167],"one":[168],"targets.":[171],"This":[172],"first":[175],"silico":[177],"study":[178],"indicate":[180],"encoding":[185],"enzymes":[186],"may":[192],"help":[193],"understand":[195],"miRNA-mediated":[197],"biosynthesis":[201]},"counts_by_year":[{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":6}],"updated_date":"2026-05-21T06:26:12.895304","created_date":"2016-06-24T00:00:00"}