{"id":"https://openalex.org/W2132850164","doi":"https://doi.org/10.1016/s1672-0229(11)60001-6","title":"Thirty Years of Multiple Sequence Codes","display_name":"Thirty Years of Multiple Sequence Codes","publication_year":2011,"publication_date":"2011-04-01","ids":{"openalex":"https://openalex.org/W2132850164","doi":"https://doi.org/10.1016/s1672-0229(11)60001-6","mag":"2132850164","pmid":"https://pubmed.ncbi.nlm.nih.gov/21641556"},"language":"en","primary_location":{"id":"doi:10.1016/s1672-0229(11)60001-6","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s1672-0229(11)60001-6","pdf_url":null,"source":{"id":"https://openalex.org/S155547894","display_name":"Genomics Proteomics & Bioinformatics","issn_l":"1672-0229","issn":["1672-0229","2210-3244"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genomics, Proteomics & Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1016/s1672-0229(11)60001-6","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110312092","display_name":"Edward N. Trifonov","orcid":null},"institutions":[{"id":"https://openalex.org/I21449261","display_name":"Masaryk University","ror":"https://ror.org/02j46qs45","country_code":"CZ","type":"education","lineage":["https://openalex.org/I21449261"]},{"id":"https://openalex.org/I91203450","display_name":"University of Haifa","ror":"https://ror.org/02f009v59","country_code":"IL","type":"education","lineage":["https://openalex.org/I91203450"]}],"countries":["CZ","IL"],"is_corresponding":true,"raw_author_name":"Edward N. Trifonov","raw_affiliation_strings":["Division of Functional Genomics and Proteomics, Faculty of Science, Masaryk University , Brno, 61137 , Czech Republic","Genome Diversity Center, Institute of Evolution, University of Haifa , Haifa, 31905 , Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Functional Genomics and Proteomics, Faculty of Science, Masaryk University , Brno, 61137 , Czech Republic","institution_ids":["https://openalex.org/I21449261"]},{"raw_affiliation_string":"Genome Diversity Center, Institute of Evolution, University of Haifa , Haifa, 31905 , Israel","institution_ids":["https://openalex.org/I91203450"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5110312092"],"corresponding_institution_ids":["https://openalex.org/I21449261","https://openalex.org/I91203450"],"apc_list":{"value":3650,"currency":"USD","value_usd":3650},"apc_paid":{"value":3650,"currency":"USD","value_usd":3650},"fwci":1.3381,"has_fulltext":false,"cited_by_count":21,"citation_normalized_percentile":{"value":0.79856332,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"9","issue":"1-2","first_page":"1","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.996999979019165,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nucleosome","display_name":"Nucleosome","score":0.8075661659240723},{"id":"https://openalex.org/keywords/code","display_name":"Code (set theory)","score":0.6100841760635376},{"id":"https://openalex.org/keywords/sequence","display_name":"Sequence (biology)","score":0.5265797972679138},{"id":"https://openalex.org/keywords/histone","display_name":"Histone","score":0.48798316717147827},{"id":"https://openalex.org/keywords/chromatin","display_name":"Chromatin","score":0.47316867113113403},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4557369351387024},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4394731819629669},{"id":"https://openalex.org/keywords/resolution","display_name":"Resolution (logic)","score":0.4109107255935669},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.4084624946117401},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3768593966960907},{"id":"https://openalex.org/keywords/dna","display_name":"DNA","score":0.32461121678352356},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.13938847184181213},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.06476688385009766}],"concepts":[{"id":"https://openalex.org/C84772758","wikidata":"https://www.wikidata.org/wiki/Q271794","display_name":"Nucleosome","level":4,"score":0.8075661659240723},{"id":"https://openalex.org/C2776760102","wikidata":"https://www.wikidata.org/wiki/Q5139990","display_name":"Code (set theory)","level":3,"score":0.6100841760635376},{"id":"https://openalex.org/C2778112365","wikidata":"https://www.wikidata.org/wiki/Q3511065","display_name":"Sequence (biology)","level":2,"score":0.5265797972679138},{"id":"https://openalex.org/C64927066","wikidata":"https://www.wikidata.org/wiki/Q36293","display_name":"Histone","level":3,"score":0.48798316717147827},{"id":"https://openalex.org/C83640560","wikidata":"https://www.wikidata.org/wiki/Q180951","display_name":"Chromatin","level":3,"score":0.47316867113113403},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4557369351387024},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4394731819629669},{"id":"https://openalex.org/C138268822","wikidata":"https://www.wikidata.org/wiki/Q1051925","display_name":"Resolution (logic)","level":2,"score":0.4109107255935669},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4084624946117401},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3768593966960907},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.32461121678352356},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.13938847184181213},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.06476688385009766},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002843","descriptor_name":"Chromatin","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002843","descriptor_name":"Chromatin","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002843","descriptor_name":"Chromatin","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002843","descriptor_name":"Chromatin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002843","descriptor_name":"Chromatin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002843","descriptor_name":"Chromatin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005815","descriptor_name":"Genetic Code","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005815","descriptor_name":"Genetic Code","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005815","descriptor_name":"Genetic Code","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009707","descriptor_name":"Nucleosomes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009707","descriptor_name":"Nucleosomes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009707","descriptor_name":"Nucleosomes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012045","descriptor_name":"Regulatory Sequences, Nucleic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012045","descriptor_name":"Regulatory Sequences, Nucleic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012045","descriptor_name":"Regulatory Sequences, Nucleic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D042002","descriptor_name":"Chromatin Assembly and Disassembly","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D042002","descriptor_name":"Chromatin Assembly and Disassembly","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D042002","descriptor_name":"Chromatin Assembly and Disassembly","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/s1672-0229(11)60001-6","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s1672-0229(11)60001-6","pdf_url":null,"source":{"id":"https://openalex.org/S155547894","display_name":"Genomics Proteomics & Bioinformatics","issn_l":"1672-0229","issn":["1672-0229","2210-3244"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genomics, Proteomics & Bioinformatics","raw_type":"journal-article"},{"id":"pmid:21641556","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21641556","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genomics, proteomics & bioinformatics","raw_type":null},{"id":"pmh:oai:europepmc.org:4016513","is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5054146","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1016/s1672-0229(11)60001-6","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s1672-0229(11)60001-6","pdf_url":null,"source":{"id":"https://openalex.org/S155547894","display_name":"Genomics Proteomics & Bioinformatics","issn_l":"1672-0229","issn":["1672-0229","2210-3244"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genomics, Proteomics & Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G2761285720","display_name":null,"funder_award_id":"FP/2007-2013","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G5593277320","display_name":null,"funder_award_id":"2007-2013","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G6300713832","display_name":null,"funder_award_id":"222/09","funder_id":"https://openalex.org/F4320322252","funder_display_name":"Israel Science Foundation"},{"id":"https://openalex.org/G8414869745","display_name":"South Moravian Programme for Distinguished Researchers","funder_award_id":"229603","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"}],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320322252","display_name":"Israel Science Foundation","ror":"https://ror.org/04sazxf24"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":49,"referenced_works":["https://openalex.org/W116158335","https://openalex.org/W341601379","https://openalex.org/W574037086","https://openalex.org/W1481397867","https://openalex.org/W1542426682","https://openalex.org/W1577271338","https://openalex.org/W1626481144","https://openalex.org/W1963602582","https://openalex.org/W1964684145","https://openalex.org/W1968569455","https://openalex.org/W1969600436","https://openalex.org/W1974089947","https://openalex.org/W1982610079","https://openalex.org/W1983685543","https://openalex.org/W1995536620","https://openalex.org/W1996852546","https://openalex.org/W2004469916","https://openalex.org/W2024462905","https://openalex.org/W2028913412","https://openalex.org/W2029853054","https://openalex.org/W2029873987","https://openalex.org/W2038074953","https://openalex.org/W2043009382","https://openalex.org/W2043382823","https://openalex.org/W2043938026","https://openalex.org/W2044830561","https://openalex.org/W2048242923","https://openalex.org/W2048540261","https://openalex.org/W2053876385","https://openalex.org/W2057781025","https://openalex.org/W2059844821","https://openalex.org/W2065090911","https://openalex.org/W2066331027","https://openalex.org/W2067301744","https://openalex.org/W2076950513","https://openalex.org/W2085154635","https://openalex.org/W2109866944","https://openalex.org/W2128377942","https://openalex.org/W2130062232","https://openalex.org/W2143658931","https://openalex.org/W2150928856","https://openalex.org/W2153975721","https://openalex.org/W2264639163","https://openalex.org/W2794485295","https://openalex.org/W3134463360","https://openalex.org/W4235677095","https://openalex.org/W4295030489","https://openalex.org/W6636484470","https://openalex.org/W6682571860"],"related_works":["https://openalex.org/W2113512405","https://openalex.org/W3124098632","https://openalex.org/W1525192260","https://openalex.org/W98379584","https://openalex.org/W2113253885","https://openalex.org/W2413824894","https://openalex.org/W2020842184","https://openalex.org/W1979616193","https://openalex.org/W2055566470","https://openalex.org/W2082280880"],"abstract_inverted_index":{"An":[0],"overview":[1],"is":[2,21,34,41],"presented":[3],"on":[4,9,82],"the":[5,16,24,49,59,83,86],"status":[6],"of":[7,18,26,29,61,70,74,80,85],"studies":[8,73],"multiple":[10,19],"codes":[11,20,50],"in":[12,23,53,58],"genetic":[13],"sequences.":[14],"Indirectly,":[15],"existence":[17],"recognized":[22],"form":[25],"several":[27],"rediscoveries":[28],"Second":[30],"Genetic":[31],"Code":[32],"that":[33],"different":[35],"each":[36],"time.":[37],"A":[38],"due":[39],"credit":[40],"given":[42],"to":[43,48],"earlier":[44],"seminal":[45],"work":[46],"related":[47],"often":[51],"neglected":[52],"literature.":[54],"The":[55],"latest":[56],"developments":[57],"field":[60],"chromatin":[62],"code":[63],"are":[64],"discussed,":[65],"as":[66,68],"well":[67],"perspectives":[69],"single-base":[71],"resolution":[72],"nucleosome":[75],"positioning,":[76],"including":[77],"rotational":[78],"setting":[79],"DNA":[81],"surface":[84],"histone":[87],"octamers.":[88]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":5}],"updated_date":"2026-07-23T08:03:31.855105","created_date":"2025-10-10T00:00:00"}