{"id":"https://openalex.org/W1504223663","doi":"https://doi.org/10.1016/s0925-2312(99)00085-5","title":"Decoding time-varying calcium signals by the postsynaptic biochemical network","display_name":"Decoding time-varying calcium signals by the postsynaptic biochemical network","publication_year":1999,"publication_date":"1999-06-01","ids":{"openalex":"https://openalex.org/W1504223663","doi":"https://doi.org/10.1016/s0925-2312(99)00085-5","mag":"1504223663"},"language":"en","primary_location":{"id":"doi:10.1016/s0925-2312(99)00085-5","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0925-2312(99)00085-5","pdf_url":null,"source":{"id":"https://openalex.org/S45693802","display_name":"Neurocomputing","issn_l":"0925-2312","issn":["0925-2312","1872-8286"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurocomputing","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005016862","display_name":"Yoshihisa Kubota","orcid":"https://orcid.org/0000-0002-2807-1535"},"institutions":[{"id":"https://openalex.org/I122411786","display_name":"California Institute of Technology","ror":"https://ror.org/05dxps055","country_code":"US","type":"education","lineage":["https://openalex.org/I122411786"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yoshihisa Kubota","raw_affiliation_strings":["California  Institute of Technology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"California  Institute of Technology","institution_ids":["https://openalex.org/I122411786"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102051795","display_name":"James M. Bower","orcid":null},"institutions":[{"id":"https://openalex.org/I122411786","display_name":"California Institute of Technology","ror":"https://ror.org/05dxps055","country_code":"US","type":"education","lineage":["https://openalex.org/I122411786"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James M Bower","raw_affiliation_strings":["California  Institute of Technology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"California  Institute of Technology","institution_ids":["https://openalex.org/I122411786"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":2470,"currency":"USD","value_usd":2470},"apc_paid":null,"fwci":0.3278,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.43316359,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"26-27","issue":null,"first_page":"29","last_page":"38"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12023","display_name":"Cholinesterase and Neurodegenerative Diseases","score":0.9986000061035156,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.998199999332428,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/postsynaptic-potential","display_name":"Postsynaptic potential","score":0.6699091196060181},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.5414748787879944},{"id":"https://openalex.org/keywords/neurotransmission","display_name":"Neurotransmission","score":0.538986086845398},{"id":"https://openalex.org/keywords/cell-biology","display_name":"Cell biology","score":0.5255243182182312},{"id":"https://openalex.org/keywords/protein-kinase-a","display_name":"Protein kinase A","score":0.4999070167541504},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.46895378828048706},{"id":"https://openalex.org/keywords/phosphodiesterase","display_name":"Phosphodiesterase","score":0.4548311233520508},{"id":"https://openalex.org/keywords/gtpase","display_name":"GTPase","score":0.4547145366668701},{"id":"https://openalex.org/keywords/postsynaptic-density","display_name":"Postsynaptic density","score":0.44886669516563416},{"id":"https://openalex.org/keywords/synaptic-fatigue","display_name":"Synaptic fatigue","score":0.42421677708625793},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.41987118124961853},{"id":"https://openalex.org/keywords/biophysics","display_name":"Biophysics","score":0.33080363273620605},{"id":"https://openalex.org/keywords/kinase","display_name":"Kinase","score":0.31779396533966064},{"id":"https://openalex.org/keywords/excitatory-postsynaptic-potential","display_name":"Excitatory postsynaptic potential","score":0.3165658712387085},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.2954137325286865},{"id":"https://openalex.org/keywords/inhibitory-postsynaptic-potential","display_name":"Inhibitory postsynaptic potential","score":0.2886771857738495},{"id":"https://openalex.org/keywords/enzyme","display_name":"Enzyme","score":0.13141414523124695},{"id":"https://openalex.org/keywords/receptor","display_name":"Receptor","score":0.11814579367637634}],"concepts":[{"id":"https://openalex.org/C197341189","wikidata":"https://www.wikidata.org/wiki/Q863533","display_name":"Postsynaptic potential","level":3,"score":0.6699091196060181},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5414748787879944},{"id":"https://openalex.org/C200170125","wikidata":"https://www.wikidata.org/wiki/Q969316","display_name":"Neurotransmission","level":3,"score":0.538986086845398},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5255243182182312},{"id":"https://openalex.org/C97029542","wikidata":"https://www.wikidata.org/wiki/Q281417","display_name":"Protein kinase A","level":3,"score":0.4999070167541504},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.46895378828048706},{"id":"https://openalex.org/C62826618","wikidata":"https://www.wikidata.org/wiki/Q424304","display_name":"Phosphodiesterase","level":3,"score":0.4548311233520508},{"id":"https://openalex.org/C207332259","wikidata":"https://www.wikidata.org/wiki/Q769143","display_name":"GTPase","level":2,"score":0.4547145366668701},{"id":"https://openalex.org/C187541742","wikidata":"https://www.wikidata.org/wiki/Q4374336","display_name":"Postsynaptic density","level":4,"score":0.44886669516563416},{"id":"https://openalex.org/C125667969","wikidata":"https://www.wikidata.org/wiki/Q7662036","display_name":"Synaptic fatigue","level":4,"score":0.42421677708625793},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.41987118124961853},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.33080363273620605},{"id":"https://openalex.org/C184235292","wikidata":"https://www.wikidata.org/wiki/Q421851","display_name":"Kinase","level":2,"score":0.31779396533966064},{"id":"https://openalex.org/C112592302","wikidata":"https://www.wikidata.org/wiki/Q1207387","display_name":"Excitatory postsynaptic potential","level":3,"score":0.3165658712387085},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2954137325286865},{"id":"https://openalex.org/C17077164","wikidata":"https://www.wikidata.org/wiki/Q1185869","display_name":"Inhibitory postsynaptic potential","level":2,"score":0.2886771857738495},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.13141414523124695},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.11814579367637634}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/s0925-2312(99)00085-5","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0925-2312(99)00085-5","pdf_url":null,"source":{"id":"https://openalex.org/S45693802","display_name":"Neurocomputing","issn_l":"0925-2312","issn":["0925-2312","1872-8286"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurocomputing","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W1641016126","https://openalex.org/W1781445228","https://openalex.org/W1969102594","https://openalex.org/W1977861693","https://openalex.org/W1998678953","https://openalex.org/W1999576398","https://openalex.org/W2030134162","https://openalex.org/W2052322593","https://openalex.org/W2060168844","https://openalex.org/W2082656140","https://openalex.org/W2087444241","https://openalex.org/W2113545093","https://openalex.org/W2129116965","https://openalex.org/W2135011583","https://openalex.org/W2140172702"],"related_works":["https://openalex.org/W2007990412","https://openalex.org/W1991729369","https://openalex.org/W2162918865","https://openalex.org/W2913382999","https://openalex.org/W1995307208","https://openalex.org/W2093315560","https://openalex.org/W2004010528","https://openalex.org/W2020453060","https://openalex.org/W1997246394","https://openalex.org/W1976629800"],"abstract_inverted_index":null,"counts_by_year":[{"year":2018,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}