{"id":"https://openalex.org/W1846257146","doi":"https://doi.org/10.1016/s0169-7161(96)13006-6","title":"4 Design and analysis of experiments: Nonparametric methods with applications to clinical trials","display_name":"4 Design and analysis of experiments: Nonparametric methods with applications to clinical trials","publication_year":1996,"publication_date":"1996-01-01","ids":{"openalex":"https://openalex.org/W1846257146","doi":"https://doi.org/10.1016/s0169-7161(96)13006-6","mag":"1846257146"},"language":"en","primary_location":{"id":"doi:10.1016/s0169-7161(96)13006-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0169-7161(96)13006-6","pdf_url":null,"source":{"id":"https://openalex.org/S44500590","display_name":"Handbook of statistics","issn_l":"0169-7161","issn":["0169-7161","1875-7448"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Handbook of Statistics","raw_type":"book-chapter"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070609086","display_name":"Pranab Kumar Sen","orcid":"https://orcid.org/0000-0003-0193-8562"},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Pranab K. Sen","raw_affiliation_strings":[],"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5070609086"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.19236884,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"91","last_page":"150"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11871","display_name":"Advanced Statistical Methods and Models","score":0.9969000220298767,"subfield":{"id":"https://openalex.org/subfields/2613","display_name":"Statistics and Probability"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11871","display_name":"Advanced Statistical Methods and Models","score":0.9969000220298767,"subfield":{"id":"https://openalex.org/subfields/2613","display_name":"Statistics and Probability"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11235","display_name":"Statistical Methods in Clinical Trials","score":0.9958999752998352,"subfield":{"id":"https://openalex.org/subfields/2613","display_name":"Statistics and Probability"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11798","display_name":"Optimal Experimental Design Methods","score":0.9950000047683716,"subfield":{"id":"https://openalex.org/subfields/1803","display_name":"Management Science and Operations Research"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nonparametric-statistics","display_name":"Nonparametric statistics","score":0.7508364915847778},{"id":"https://openalex.org/keywords/homoscedasticity","display_name":"Homoscedasticity","score":0.6951422691345215},{"id":"https://openalex.org/keywords/statistical-hypothesis-testing","display_name":"Statistical hypothesis testing","score":0.577399492263794},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.5632585287094116},{"id":"https://openalex.org/keywords/null-hypothesis","display_name":"Null hypothesis","score":0.5414007902145386},{"id":"https://openalex.org/keywords/parametric-statistics","display_name":"Parametric statistics","score":0.5213205218315125},{"id":"https://openalex.org/keywords/sample-size-determination","display_name":"Sample size determination","score":0.4798107445240021},{"id":"https://openalex.org/keywords/alternative-hypothesis","display_name":"Alternative hypothesis","score":0.4444350302219391},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.4398079812526703},{"id":"https://openalex.org/keywords/robustness","display_name":"Robustness (evolution)","score":0.4391454756259918},{"id":"https://openalex.org/keywords/design-of-experiments","display_name":"Design of experiments","score":0.41345980763435364},{"id":"https://openalex.org/keywords/econometrics","display_name":"Econometrics","score":0.3841959834098816},{"id":"https://openalex.org/keywords/heteroscedasticity","display_name":"Heteroscedasticity","score":0.377157986164093}],"concepts":[{"id":"https://openalex.org/C102366305","wikidata":"https://www.wikidata.org/wiki/Q1097688","display_name":"Nonparametric statistics","level":2,"score":0.7508364915847778},{"id":"https://openalex.org/C104409967","wikidata":"https://www.wikidata.org/wiki/Q1054836","display_name":"Homoscedasticity","level":3,"score":0.6951422691345215},{"id":"https://openalex.org/C87007009","wikidata":"https://www.wikidata.org/wiki/Q210832","display_name":"Statistical hypothesis testing","level":2,"score":0.577399492263794},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.5632585287094116},{"id":"https://openalex.org/C191988596","wikidata":"https://www.wikidata.org/wiki/Q628374","display_name":"Null hypothesis","level":2,"score":0.5414007902145386},{"id":"https://openalex.org/C117251300","wikidata":"https://www.wikidata.org/wiki/Q1849855","display_name":"Parametric statistics","level":2,"score":0.5213205218315125},{"id":"https://openalex.org/C129848803","wikidata":"https://www.wikidata.org/wiki/Q2564360","display_name":"Sample size determination","level":2,"score":0.4798107445240021},{"id":"https://openalex.org/C120577422","wikidata":"https://www.wikidata.org/wiki/Q843558","display_name":"Alternative hypothesis","level":3,"score":0.4444350302219391},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.4398079812526703},{"id":"https://openalex.org/C63479239","wikidata":"https://www.wikidata.org/wiki/Q7353546","display_name":"Robustness (evolution)","level":3,"score":0.4391454756259918},{"id":"https://openalex.org/C34559072","wikidata":"https://www.wikidata.org/wiki/Q2334061","display_name":"Design of experiments","level":2,"score":0.41345980763435364},{"id":"https://openalex.org/C149782125","wikidata":"https://www.wikidata.org/wiki/Q160039","display_name":"Econometrics","level":1,"score":0.3841959834098816},{"id":"https://openalex.org/C101104100","wikidata":"https://www.wikidata.org/wiki/Q1063540","display_name":"Heteroscedasticity","level":2,"score":0.377157986164093},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1016/s0169-7161(96)13006-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0169-7161(96)13006-6","pdf_url":null,"source":{"id":"https://openalex.org/S44500590","display_name":"Handbook of statistics","issn_l":"0169-7161","issn":["0169-7161","1875-7448"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Handbook of Statistics","raw_type":"book-chapter"},{"id":"pmh:oai:repository.lib.ncsu.edu:1840.4/3746","is_oa":false,"landing_page_url":"http://www.lib.ncsu.edu/resolver/1840.4/3746","pdf_url":null,"source":{"id":"https://openalex.org/S4306402468","display_name":"NCSU Libraries Repository (North Carolina State University Libraries)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I137902535","host_organization_name":"North Carolina State University","host_organization_lineage":["https://openalex.org/I137902535"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Technical report"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":131,"referenced_works":["https://openalex.org/W241544943","https://openalex.org/W627307755","https://openalex.org/W644721740","https://openalex.org/W656022232","https://openalex.org/W1142896015","https://openalex.org/W1532184042","https://openalex.org/W1548789842","https://openalex.org/W1560339429","https://openalex.org/W1859463534","https://openalex.org/W1964874140","https://openalex.org/W1965151545","https://openalex.org/W1967138568","https://openalex.org/W1969836247","https://openalex.org/W1972676917","https://openalex.org/W1974758710","https://openalex.org/W1978693052","https://openalex.org/W1978974464","https://openalex.org/W1980098418","https://openalex.org/W1981591026","https://openalex.org/W1982321539","https://openalex.org/W1986449665","https://openalex.org/W1989029592","https://openalex.org/W1990382934","https://openalex.org/W1990639292","https://openalex.org/W1994258869","https://openalex.org/W2001234488","https://openalex.org/W2001374746","https://openalex.org/W2001942620","https://openalex.org/W2008434876","https://openalex.org/W2010742436","https://openalex.org/W2011058124","https://openalex.org/W2012712694","https://openalex.org/W2012996248","https://openalex.org/W2013194198","https://openalex.org/W2013784666","https://openalex.org/W2016368041","https://openalex.org/W2017912706","https://openalex.org/W2018764772","https://openalex.org/W2020996779","https://openalex.org/W2023902665","https://openalex.org/W2025115476","https://openalex.org/W2028785275","https://openalex.org/W2030296667","https://openalex.org/W2036937500","https://openalex.org/W2041918822","https://openalex.org/W2042392494","https://openalex.org/W2042421456","https://openalex.org/W2043038742","https://openalex.org/W2045941204","https://openalex.org/W2057968703","https://openalex.org/W2059930367","https://openalex.org/W2063158463","https://openalex.org/W2063318435","https://openalex.org/W2064299318","https://openalex.org/W2076327797","https://openalex.org/W2079158545","https://openalex.org/W2082537504","https://openalex.org/W2082779372","https://openalex.org/W2082941118","https://openalex.org/W2085782272","https://openalex.org/W2086909498","https://openalex.org/W2092648747","https://openalex.org/W2097952480","https://openalex.org/W2098822264","https://openalex.org/W2127600891","https://openalex.org/W2148347826","https://openalex.org/W2149106352","https://openalex.org/W2150000105","https://openalex.org/W2155949904","https://openalex.org/W2156841141","https://openalex.org/W2159656320","https://openalex.org/W2171465810","https://openalex.org/W2313048332","https://openalex.org/W2319384619","https://openalex.org/W2320973159","https://openalex.org/W2321305532","https://openalex.org/W2321574194","https://openalex.org/W2323863961","https://openalex.org/W2334986623","https://openalex.org/W2395026993","https://openalex.org/W2507353306","https://openalex.org/W2509304110","https://openalex.org/W2519802324","https://openalex.org/W2520685853","https://openalex.org/W2522792857","https://openalex.org/W2523729073","https://openalex.org/W2525340501","https://openalex.org/W2525690827","https://openalex.org/W2584244722","https://openalex.org/W2763110165","https://openalex.org/W2795759509","https://openalex.org/W2796862431","https://openalex.org/W2797145945","https://openalex.org/W2797515602","https://openalex.org/W2802050701","https://openalex.org/W2945608433","https://openalex.org/W2991655026","https://openalex.org/W2995133996","https://openalex.org/W3015695384","https://openalex.org/W3015818759","https://openalex.org/W3028100754","https://openalex.org/W3142640589","https://openalex.org/W3147894994","https://openalex.org/W3190417764","https://openalex.org/W4205704423","https://openalex.org/W4231430016","https://openalex.org/W4236818056","https://openalex.org/W4240442581","https://openalex.org/W4241727697","https://openalex.org/W4242589154","https://openalex.org/W4245608963","https://openalex.org/W4245958676","https://openalex.org/W4253101013","https://openalex.org/W4285719527","https://openalex.org/W4297924266","https://openalex.org/W4299922653","https://openalex.org/W4301420330","https://openalex.org/W6627471968","https://openalex.org/W6632860851","https://openalex.org/W6644833923","https://openalex.org/W6650870423","https://openalex.org/W6661416367","https://openalex.org/W6661866550","https://openalex.org/W6679237366","https://openalex.org/W6682308145","https://openalex.org/W6683435013","https://openalex.org/W6711975505","https://openalex.org/W6727395136","https://openalex.org/W6727600341","https://openalex.org/W6799804512","https://openalex.org/W7073826752"],"related_works":["https://openalex.org/W2051354704","https://openalex.org/W2582496451","https://openalex.org/W2065460266","https://openalex.org/W2380616114","https://openalex.org/W3202682398","https://openalex.org/W2413996692","https://openalex.org/W2732151112","https://openalex.org/W2388528498","https://openalex.org/W3128240669","https://openalex.org/W2166803271"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-04-05T17:49:38.594831","created_date":"2025-10-10T00:00:00"}