{"id":"https://openalex.org/W201789006","doi":"https://doi.org/10.1016/s0169-7161(00)18035-6","title":"33 Methods of establishing in vitro-in vivo relationships for modified release drug products","display_name":"33 Methods of establishing in vitro-in vivo relationships for modified release drug products","publication_year":2000,"publication_date":"2000-01-01","ids":{"openalex":"https://openalex.org/W201789006","doi":"https://doi.org/10.1016/s0169-7161(00)18035-6","mag":"201789006"},"language":"en","primary_location":{"id":"doi:10.1016/s0169-7161(00)18035-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0169-7161(00)18035-6","pdf_url":null,"source":{"id":"https://openalex.org/S44500590","display_name":"Handbook of statistics","issn_l":"0169-7161","issn":["0169-7161","1875-7448"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Handbook of Statistics","raw_type":"book-chapter"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5069917433","display_name":"David T. Mauger","orcid":"https://orcid.org/0000-0002-4663-5285"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David T. Mauger","raw_affiliation_strings":["Department of Public Health Sciences"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Public Health Sciences","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5007734319","display_name":"Vernon M. Chinchilli","orcid":"https://orcid.org/0000-0001-6488-7809"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Vernon M. Chinchilli","raw_affiliation_strings":["Department of Public Health Sciences"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Public Health Sciences","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.1176,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.81818182,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":95},"biblio":{"volume":null,"issue":null,"first_page":"977","last_page":"1002"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10908","display_name":"Analytical Chemistry and Chromatography","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11124","display_name":"Protein purification and stability","score":0.9943000078201294,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/in-vivo","display_name":"In vivo","score":0.6621848344802856},{"id":"https://openalex.org/keywords/drug","display_name":"Drug","score":0.5719687938690186},{"id":"https://openalex.org/keywords/in-vitro","display_name":"In vitro","score":0.5502637624740601},{"id":"https://openalex.org/keywords/pharmacology","display_name":"Pharmacology","score":0.5043269395828247},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.39782190322875977},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.2159392237663269},{"id":"https://openalex.org/keywords/biotechnology","display_name":"Biotechnology","score":0.13328105211257935},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.13215288519859314},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.08540195226669312}],"concepts":[{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.6621848344802856},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.5719687938690186},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.5502637624740601},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5043269395828247},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.39782190322875977},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2159392237663269},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.13328105211257935},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.13215288519859314},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.08540195226669312}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/s0169-7161(00)18035-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0169-7161(00)18035-6","pdf_url":null,"source":{"id":"https://openalex.org/S44500590","display_name":"Handbook of statistics","issn_l":"0169-7161","issn":["0169-7161","1875-7448"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Handbook of Statistics","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/2","score":0.5099999904632568,"display_name":"Zero hunger"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":60,"referenced_works":["https://openalex.org/W36991856","https://openalex.org/W37851286","https://openalex.org/W40953446","https://openalex.org/W41724885","https://openalex.org/W53376986","https://openalex.org/W59153527","https://openalex.org/W94117095","https://openalex.org/W99333352","https://openalex.org/W100671061","https://openalex.org/W106226478","https://openalex.org/W119395235","https://openalex.org/W122913527","https://openalex.org/W133489080","https://openalex.org/W163976669","https://openalex.org/W174258964","https://openalex.org/W311948854","https://openalex.org/W1498305210","https://openalex.org/W1593241028","https://openalex.org/W1601833061","https://openalex.org/W1965689538","https://openalex.org/W1972447012","https://openalex.org/W1984850594","https://openalex.org/W1997722637","https://openalex.org/W2005918565","https://openalex.org/W2014995495","https://openalex.org/W2015328770","https://openalex.org/W2032655898","https://openalex.org/W2033406972","https://openalex.org/W2038042827","https://openalex.org/W2042038604","https://openalex.org/W2059623859","https://openalex.org/W2061673014","https://openalex.org/W2064921242","https://openalex.org/W2122296694","https://openalex.org/W2125664736","https://openalex.org/W2134810964","https://openalex.org/W2152186576","https://openalex.org/W2238246598","https://openalex.org/W2329176484","https://openalex.org/W2333699965","https://openalex.org/W2410060119","https://openalex.org/W2411588691","https://openalex.org/W2415889362","https://openalex.org/W2417471590","https://openalex.org/W2502670554","https://openalex.org/W2884819971","https://openalex.org/W2916919348","https://openalex.org/W6601501639","https://openalex.org/W6601520451","https://openalex.org/W6601689362","https://openalex.org/W6602396337","https://openalex.org/W6603920267","https://openalex.org/W6604061390","https://openalex.org/W6604322874","https://openalex.org/W6604875793","https://openalex.org/W6605086404","https://openalex.org/W6605518655","https://openalex.org/W6635289216","https://openalex.org/W6690134684","https://openalex.org/W6888730904"],"related_works":["https://openalex.org/W2138350991","https://openalex.org/W2409285845","https://openalex.org/W2434195791","https://openalex.org/W1566729005","https://openalex.org/W3015376786","https://openalex.org/W1700716001","https://openalex.org/W2054843986","https://openalex.org/W2116210813","https://openalex.org/W2013908504","https://openalex.org/W2440701365"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}