{"id":"https://openalex.org/W7163744662","doi":"https://doi.org/10.1016/j.neuroimage.2026.122020","title":"EEG functional connectivity methods for seizure-related disorders","display_name":"EEG functional connectivity methods for seizure-related disorders","publication_year":2026,"publication_date":"2026-06-06","ids":{"openalex":"https://openalex.org/W7163744662","doi":"https://doi.org/10.1016/j.neuroimage.2026.122020","pmid":"https://pubmed.ncbi.nlm.nih.gov/42252041"},"language":"en","primary_location":{"id":"doi:10.1016/j.neuroimage.2026.122020","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.neuroimage.2026.122020","pdf_url":null,"source":{"id":"https://openalex.org/S103225281","display_name":"NeuroImage","issn_l":"1053-8119","issn":["1053-8119","1095-9572"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroImage","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1016/j.neuroimage.2026.122020","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103138620","display_name":"Lise Cottin","orcid":"https://orcid.org/0009-0006-6751-6054"},"institutions":[{"id":"https://openalex.org/I132053463","display_name":"Universit\u00e9 Libre de Bruxelles","ror":"https://ror.org/01r9htc13","country_code":"BE","type":"education","lineage":["https://openalex.org/I132053463"]}],"countries":["BE"],"is_corresponding":true,"raw_author_name":"Lise Cottin","raw_affiliation_strings":["BEAMS-BioMechatronics Department of \u00c9cole Polytechnique de Bruxelles, Universit\u00e9 libre de Bruxelles (ULB), Avenue Franklin Roosevelt 50 1050 Brussels, Belgium. Electronic address: lise.cottin@ulb.be"],"raw_orcid":"https://orcid.org/0009-0006-6751-6054","affiliations":[{"raw_affiliation_string":"BEAMS-BioMechatronics Department of \u00c9cole Polytechnique de Bruxelles, Universit\u00e9 libre de Bruxelles (ULB), Avenue Franklin Roosevelt 50 1050 Brussels, Belgium. Electronic address: lise.cottin@ulb.be","institution_ids":["https://openalex.org/I132053463"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055667384","display_name":"Charlotte Damien","orcid":"https://orcid.org/0000-0002-8008-3947"},"institutions":[{"id":"https://openalex.org/I2802054198","display_name":"Erasmus Hospital","ror":"https://ror.org/05j1gs298","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I2802054198"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Charlotte Damien","raw_affiliation_strings":["Neurology Department of H\u00f4pital Universitaire de Bruxelles (H.U.B), H\u00f4pital Erasme, ULB, Route de Lennik 808 1070 Brussels, Belgium. Electronic address: charlotte.damien@ulb.be"],"raw_orcid":"https://orcid.org/0000-0002-8008-3947","affiliations":[{"raw_affiliation_string":"Neurology Department of H\u00f4pital Universitaire de Bruxelles (H.U.B), H\u00f4pital Erasme, ULB, Route de Lennik 808 1070 Brussels, Belgium. Electronic address: charlotte.damien@ulb.be","institution_ids":["https://openalex.org/I2802054198"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081756828","display_name":"Luca Anzalone","orcid":"https://orcid.org/0000-0002-0399-8836"},"institutions":[{"id":"https://openalex.org/I2802054198","display_name":"Erasmus Hospital","ror":"https://ror.org/05j1gs298","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I2802054198"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Luca Anzalone","raw_affiliation_strings":["Neurology Department of H\u00f4pital Universitaire de Bruxelles (H.U.B), H\u00f4pital Erasme, ULB, Route de Lennik 808 1070 Brussels, Belgium. Electronic address: luca.anzalone@ulb.be"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurology Department of H\u00f4pital Universitaire de Bruxelles (H.U.B), H\u00f4pital Erasme, ULB, Route de Lennik 808 1070 Brussels, Belgium. Electronic address: luca.anzalone@ulb.be","institution_ids":["https://openalex.org/I2802054198"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015577135","display_name":"Alec Aeby","orcid":"https://orcid.org/0000-0002-7516-665X"},"institutions":[{"id":"https://openalex.org/I4210108467","display_name":"Queen Fabiola Children's University Hospital","ror":"https://ror.org/01t5yh786","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I4210108467"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Alec Aeby","raw_affiliation_strings":["Pediatric Neurology Department of H.U.B, H\u00f4pital Universitaire des Enfants Reine Fabiola, ULB, Avenue Jean-Joseph Crocq 15 1020 Brussels, Belgium. Electronic address: alec.aeby@ulb.be"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pediatric Neurology Department of H.U.B, H\u00f4pital Universitaire des Enfants Reine Fabiola, ULB, Avenue Jean-Joseph Crocq 15 1020 Brussels, Belgium. Electronic address: alec.aeby@ulb.be","institution_ids":["https://openalex.org/I4210108467"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000864460","display_name":"Nicolas Gaspard","orcid":"https://orcid.org/0000-0003-1148-6723"},"institutions":[{"id":"https://openalex.org/I2802054198","display_name":"Erasmus Hospital","ror":"https://ror.org/05j1gs298","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I2802054198"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Nicolas Gaspard","raw_affiliation_strings":["Neurology Department of H\u00f4pital Universitaire de Bruxelles (H.U.B), H\u00f4pital Erasme, ULB, Route de Lennik 808 1070 Brussels, Belgium. Electronic address: nicolas.gaspard@ulb.be"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurology Department of H\u00f4pital Universitaire de Bruxelles (H.U.B), H\u00f4pital Erasme, ULB, Route de Lennik 808 1070 Brussels, Belgium. Electronic address: nicolas.gaspard@ulb.be","institution_ids":["https://openalex.org/I2802054198"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5018510897","display_name":"Antoine Nonclercq","orcid":"https://orcid.org/0000-0003-0292-9588"},"institutions":[{"id":"https://openalex.org/I132053463","display_name":"Universit\u00e9 Libre de Bruxelles","ror":"https://ror.org/01r9htc13","country_code":"BE","type":"education","lineage":["https://openalex.org/I132053463"]}],"countries":["BE"],"is_corresponding":true,"raw_author_name":"Antoine Nonclercq","raw_affiliation_strings":["BEAMS-BioMechatronics Department of \u00c9cole Polytechnique de Bruxelles, Universit\u00e9 libre de Bruxelles (ULB), Avenue Franklin Roosevelt 50 1050 Brussels, Belgium. Electronic address: antoine.nonclercq@ulb.be"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BEAMS-BioMechatronics Department of \u00c9cole Polytechnique de Bruxelles, Universit\u00e9 libre de Bruxelles (ULB), Avenue Franklin Roosevelt 50 1050 Brussels, Belgium. Electronic address: antoine.nonclercq@ulb.be","institution_ids":["https://openalex.org/I132053463"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5018510897","https://openalex.org/A5103138620"],"corresponding_institution_ids":["https://openalex.org/I132053463"],"apc_list":{"value":3450,"currency":"USD","value_usd":3450},"apc_paid":{"value":3450,"currency":"USD","value_usd":3450},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.89625264,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"338","issue":null,"first_page":"122020","last_page":"122020"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.382999986410141,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.382999986410141,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":0.382099986076355,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11334","display_name":"Psychosomatic Disorders and Their Treatments","score":0.015200000256299973,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/functional-connectivity","display_name":"Functional connectivity","score":0.6870999932289124},{"id":"https://openalex.org/keywords/electroencephalography","display_name":"Electroencephalography","score":0.6324999928474426},{"id":"https://openalex.org/keywords/eeg-fmri","display_name":"EEG-fMRI","score":0.4537999927997589},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.36559998989105225},{"id":"https://openalex.org/keywords/brain-mapping","display_name":"Brain mapping","score":0.30070000886917114}],"concepts":[{"id":"https://openalex.org/C3018011982","wikidata":"https://www.wikidata.org/wiki/Q7316120","display_name":"Functional connectivity","level":2,"score":0.6870999932289124},{"id":"https://openalex.org/C522805319","wikidata":"https://www.wikidata.org/wiki/Q179965","display_name":"Electroencephalography","level":2,"score":0.6324999928474426},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5799999833106995},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5724999904632568},{"id":"https://openalex.org/C125990524","wikidata":"https://www.wikidata.org/wiki/Q5322921","display_name":"EEG-fMRI","level":3,"score":0.4537999927997589},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.36559998989105225},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3555999994277954},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.30730000138282776},{"id":"https://openalex.org/C50231774","wikidata":"https://www.wikidata.org/wiki/Q639842","display_name":"Brain mapping","level":2,"score":0.30070000886917114},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2831999957561493},{"id":"https://openalex.org/C58693492","wikidata":"https://www.wikidata.org/wiki/Q551875","display_name":"Neuroimaging","level":2,"score":0.26010000705718994}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1016/j.neuroimage.2026.122020","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.neuroimage.2026.122020","pdf_url":null,"source":{"id":"https://openalex.org/S103225281","display_name":"NeuroImage","issn_l":"1053-8119","issn":["1053-8119","1095-9572"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroImage","raw_type":"journal-article"},{"id":"pmid:42252041","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42252041","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroImage","raw_type":null}],"best_oa_location":{"id":"doi:10.1016/j.neuroimage.2026.122020","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.neuroimage.2026.122020","pdf_url":null,"source":{"id":"https://openalex.org/S103225281","display_name":"NeuroImage","issn_l":"1053-8119","issn":["1053-8119","1095-9572"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroImage","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321390","display_name":"Fonds De La Recherche Scientifique - FNRS","ror":"https://ror.org/03q83t159"},{"id":"https://openalex.org/F4320322852","display_name":"Innoviris","ror":"https://ror.org/04af9zr29"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":46,"referenced_works":["https://openalex.org/W1680137270","https://openalex.org/W1966641148","https://openalex.org/W1967099253","https://openalex.org/W1972724226","https://openalex.org/W1973656456","https://openalex.org/W2019118694","https://openalex.org/W2027021543","https://openalex.org/W2043670955","https://openalex.org/W2045443845","https://openalex.org/W2068252829","https://openalex.org/W2077491345","https://openalex.org/W2079059681","https://openalex.org/W2079426910","https://openalex.org/W2109100179","https://openalex.org/W2110065044","https://openalex.org/W2115810652","https://openalex.org/W2145737016","https://openalex.org/W2146406922","https://openalex.org/W2167822639","https://openalex.org/W2227520796","https://openalex.org/W2345475267","https://openalex.org/W2488633993","https://openalex.org/W2556806676","https://openalex.org/W2563603498","https://openalex.org/W2762002773","https://openalex.org/W2927702442","https://openalex.org/W2943341715","https://openalex.org/W2949763225","https://openalex.org/W2950075555","https://openalex.org/W2953582831","https://openalex.org/W2964772360","https://openalex.org/W3007180205","https://openalex.org/W3080571847","https://openalex.org/W3094679078","https://openalex.org/W3102597665","https://openalex.org/W4220990576","https://openalex.org/W4225295961","https://openalex.org/W4281839697","https://openalex.org/W4295519935","https://openalex.org/W4297542311","https://openalex.org/W4327954168","https://openalex.org/W4389476056","https://openalex.org/W4399780596","https://openalex.org/W4404800542","https://openalex.org/W4416961061","https://openalex.org/W7153229343"],"related_works":[],"abstract_inverted_index":{"EEG":[0,48,187,219],"functional":[1,188],"connectivity":[2,17,32,90,123,179,189,220],"analysis":[3],"is":[4],"increasingly":[5],"used":[6],"to":[7,43,97],"study":[8,205],"neurological":[9],"disorders.":[10],"However,":[11],"the":[12,26,168,174,184,198,215],"lack":[13],"of":[14,170,176,186,201,217],"standardization":[15],"in":[16,31,39,129,193,222],"estimation":[18],"limits":[19],"its":[20],"clinical":[21,171,223],"translation.":[22],"This":[23,204],"work":[24],"addresses":[25],"need":[27],"for":[28,94,178,209],"more":[29],"guidance":[30],"pipeline":[33,211],"design":[34,212],"by":[35,59,78,110],"evaluating":[36],"numerous":[37],"techniques":[38],"two":[40,53],"seizure-related":[41,194],"disorders":[42],"identify":[44],"optimal":[45],"approaches.":[46],"Retrospective":[47],"data":[49],"were":[50,92,108,125],"analyzed":[51],"from":[52],"cohorts:":[54],"acutely":[55],"ill":[56],"adults":[57],"stratified":[58,77],"seizure":[60],"occurrence":[61],"(140":[62],"patients;":[63,82],"70":[64],"with":[65,69,73,84],"seizures),":[66],"and":[67,104,119,144,149,213],"children":[68],"self-limited":[70],"focal":[71],"epilepsy":[72],"centro-temporal":[74],"spikes":[75],"(SeLECTS)":[76],"cognitive":[79],"regression":[80],"(32":[81],"16":[83],"regression).":[85],"In":[86],"each":[87],"cohort,":[88],"960":[89],"pipelines":[91],"evaluated":[93],"their":[95],"ability":[96],"discriminate":[98],"between":[99,127],"sub-groups":[100,128],"using":[101,133],"statistical":[102],"testing":[103],"logistic":[105],"regression.":[106],"Pipelines":[107,132],"constructed":[109],"systematically":[111],"varying":[112],"re-referencing":[113],"schemes,":[114],"frequency":[115],"bands,":[116],"association":[117,135],"measures,":[118],"network":[120,145],"features.":[121],"Significant":[122],"differences":[124],"observed":[126],"both":[130],"cohorts.":[131],"corrected":[134,138],"measures":[136],"(e.g.,":[137,151],"correlation,":[139],"weighted":[140],"phase":[141],"lag":[142],"index)":[143],"features":[146],"capturing":[147],"integration":[148],"segregation":[150],"characteristic":[152],"path":[153],"length,":[154],"clustering":[155],"coefficient)":[156],"consistently":[157],"showed":[158],"superior":[159],"performance.":[160],"Pipeline":[161],"rankings":[162],"differed":[163],"substantially":[164],"across":[165],"disorders,":[166],"underscoring":[167],"importance":[169],"context":[172],"on":[173],"choice":[175],"parameters":[177],"analysis.":[180],"These":[181],"findings":[182],"demonstrate":[183],"potential":[185],"as":[190],"a":[191],"biomarker":[192],"conditions,":[195],"while":[196],"emphasizing":[197],"critical":[199],"impact":[200],"methodological":[202],"choices.":[203],"provides":[206],"quantitative":[207],"guidelines":[208],"informed":[210],"supports":[214],"development":[216],"automated":[218],"analyses":[221],"practice.":[224]},"counts_by_year":[],"updated_date":"2026-06-14T06:11:07.267592","created_date":"2026-06-07T00:00:00"}