{"id":"https://openalex.org/W4200330438","doi":"https://doi.org/10.1016/j.neuroimage.2021.118829","title":"Escitalopram modulates learning content-specific neuroplasticity of functional brain networks","display_name":"Escitalopram modulates learning content-specific neuroplasticity of functional brain networks","publication_year":2021,"publication_date":"2021-12-16","ids":{"openalex":"https://openalex.org/W4200330438","doi":"https://doi.org/10.1016/j.neuroimage.2021.118829","pmid":"https://pubmed.ncbi.nlm.nih.gov/34923134"},"language":"en","primary_location":{"id":"doi:10.1016/j.neuroimage.2021.118829","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.neuroimage.2021.118829","pdf_url":null,"source":{"id":"https://openalex.org/S103225281","display_name":"NeuroImage","issn_l":"1053-8119","issn":["1053-8119","1095-9572"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroImage","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1016/j.neuroimage.2021.118829","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047068471","display_name":"Manfred Kl\u00f6bl","orcid":"https://orcid.org/0000-0003-2107-8803"},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Manfred Kl\u00f6bl","raw_affiliation_strings":["Department of Psychiatry and Psychotherapy, Medical University of Vienna, Spitalgasse 23, Vienna 1090, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry and Psychotherapy, Medical University of Vienna, Spitalgasse 23, Vienna 1090, Austria","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064510883","display_name":"Ren\u00e9 Seiger","orcid":"https://orcid.org/0000-0003-1556-4346"},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Ren\u00e9 Seiger","raw_affiliation_strings":["Department of Psychiatry and Psychotherapy, Medical University of Vienna, Spitalgasse 23, Vienna 1090, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry and Psychotherapy, Medical University of Vienna, Spitalgasse 23, Vienna 1090, Austria","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016959035","display_name":"Thomas Vanicek","orcid":"https://orcid.org/0000-0002-5116-9899"},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Thomas Vanicek","raw_affiliation_strings":["Department of Psychiatry and Psychotherapy, Medical University of Vienna, Spitalgasse 23, Vienna 1090, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry and Psychotherapy, Medical University of Vienna, Spitalgasse 23, Vienna 1090, Austria","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018021326","display_name":"Patricia Handschuh","orcid":"https://orcid.org/0000-0003-3524-3646"},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Patricia Handschuh","raw_affiliation_strings":["Department of Psychiatry and Psychotherapy, Medical University of Vienna, Spitalgasse 23, Vienna 1090, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry and Psychotherapy, Medical University of Vienna, Spitalgasse 23, Vienna 1090, Austria","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091881379","display_name":"Murray Bruce Reed","orcid":"https://orcid.org/0000-0002-4873-608X"},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Murray Bruce Reed","raw_affiliation_strings":["Department of Psychiatry and Psychotherapy, Medical University of Vienna, Spitalgasse 23, Vienna 1090, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry and Psychotherapy, Medical University of Vienna, Spitalgasse 23, Vienna 1090, Austria","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051975073","display_name":"Benjamin Spurny\u2010Dworak","orcid":"https://orcid.org/0000-0003-0230-1918"},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Benjamin Spurny-Dworak","raw_affiliation_strings":["Department of Psychiatry and Psychotherapy, Medical University of Vienna, Spitalgasse 23, Vienna 1090, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry and Psychotherapy, Medical University of Vienna, Spitalgasse 23, Vienna 1090, Austria","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055220184","display_name":"Vera Ritter","orcid":null},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Vera Ritter","raw_affiliation_strings":["Department of Psychiatry and Psychotherapy, Medical University of Vienna, Spitalgasse 23, Vienna 1090, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry and Psychotherapy, Medical University of Vienna, Spitalgasse 23, Vienna 1090, Austria","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065725115","display_name":"Godber Mathis Godbersen","orcid":"https://orcid.org/0000-0002-9739-0724"},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Godber Mathis Godbersen","raw_affiliation_strings":["Department of Psychiatry and Psychotherapy, Medical University of Vienna, Spitalgasse 23, Vienna 1090, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry and Psychotherapy, Medical University of Vienna, Spitalgasse 23, Vienna 1090, Austria","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025247342","display_name":"Gregor Gryglewski","orcid":"https://orcid.org/0000-0002-7344-8071"},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Gregor Gryglewski","raw_affiliation_strings":["Department of Psychiatry and Psychotherapy, Medical University of Vienna, Spitalgasse 23, Vienna 1090, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry and Psychotherapy, Medical University of Vienna, Spitalgasse 23, Vienna 1090, Austria","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016435392","display_name":"Christoph Kraus","orcid":"https://orcid.org/0000-0002-7144-2282"},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Christoph Kraus","raw_affiliation_strings":["Department of Psychiatry and Psychotherapy, Medical University of Vienna, Spitalgasse 23, Vienna 1090, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry and Psychotherapy, Medical University of Vienna, Spitalgasse 23, Vienna 1090, Austria","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032669789","display_name":"Andreas Hahn","orcid":"https://orcid.org/0000-0001-9727-7580"},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Andreas Hahn","raw_affiliation_strings":["Department of Psychiatry and Psychotherapy, Medical University of Vienna, Spitalgasse 23, Vienna 1090, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry and Psychotherapy, Medical University of Vienna, Spitalgasse 23, Vienna 1090, Austria","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5023419818","display_name":"Rupert Lanzenberger","orcid":"https://orcid.org/0000-0003-4641-9539"},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":true,"raw_author_name":"Rupert Lanzenberger","raw_affiliation_strings":["Department of Psychiatry and Psychotherapy, Medical University of Vienna, Spitalgasse 23, Vienna 1090, Austria. Electronic address: rupert.lanzenberger@meduniwien.ac.at","Department of Psychiatry and Psychotherapy, Medical University of Vienna, Spitalgasse 23, Vienna 1090, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry and Psychotherapy, Medical University of Vienna, Spitalgasse 23, Vienna 1090, Austria. Electronic address: rupert.lanzenberger@meduniwien.ac.at","institution_ids":[]},{"raw_affiliation_string":"Department of Psychiatry and Psychotherapy, Medical University of Vienna, Spitalgasse 23, Vienna 1090, Austria","institution_ids":["https://openalex.org/I76134821"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5023419818"],"corresponding_institution_ids":["https://openalex.org/I76134821"],"apc_list":{"value":3450,"currency":"USD","value_usd":3450},"apc_paid":{"value":3450,"currency":"USD","value_usd":3450},"fwci":2.4211,"has_fulltext":false,"cited_by_count":30,"citation_normalized_percentile":{"value":0.89202304,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"247","issue":null,"first_page":"118829","last_page":"118829"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10448","display_name":"Memory and Neural Mechanisms","score":0.9972000122070312,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neuroplasticity","display_name":"Neuroplasticity","score":0.7603302001953125},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.6957131028175354},{"id":"https://openalex.org/keywords/prefrontal-cortex","display_name":"Prefrontal cortex","score":0.6909648776054382},{"id":"https://openalex.org/keywords/escitalopram","display_name":"Escitalopram","score":0.6385348439216614},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.6116986870765686},{"id":"https://openalex.org/keywords/functional-magnetic-resonance-imaging","display_name":"Functional magnetic resonance imaging","score":0.4611189365386963},{"id":"https://openalex.org/keywords/context","display_name":"Context (archaeology)","score":0.4203081727027893},{"id":"https://openalex.org/keywords/cognition","display_name":"Cognition","score":0.2607356309890747},{"id":"https://openalex.org/keywords/hippocampus","display_name":"Hippocampus","score":0.22716480493545532},{"id":"https://openalex.org/keywords/antidepressant","display_name":"Antidepressant","score":0.0830078125}],"concepts":[{"id":"https://openalex.org/C47611674","wikidata":"https://www.wikidata.org/wiki/Q849491","display_name":"Neuroplasticity","level":2,"score":0.7603302001953125},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.6957131028175354},{"id":"https://openalex.org/C2781195155","wikidata":"https://www.wikidata.org/wiki/Q18680","display_name":"Prefrontal cortex","level":3,"score":0.6909648776054382},{"id":"https://openalex.org/C2779583969","wikidata":"https://www.wikidata.org/wiki/Q423757","display_name":"Escitalopram","level":4,"score":0.6385348439216614},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6116986870765686},{"id":"https://openalex.org/C2779226451","wikidata":"https://www.wikidata.org/wiki/Q903809","display_name":"Functional magnetic resonance imaging","level":2,"score":0.4611189365386963},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.4203081727027893},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.2607356309890747},{"id":"https://openalex.org/C2781161787","wikidata":"https://www.wikidata.org/wiki/Q48360","display_name":"Hippocampus","level":2,"score":0.22716480493545532},{"id":"https://openalex.org/C2779177272","wikidata":"https://www.wikidata.org/wiki/Q76560","display_name":"Antidepressant","level":3,"score":0.0830078125},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000089983","descriptor_name":"Escitalopram","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000089983","descriptor_name":"Escitalopram","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000089983","descriptor_name":"Escitalopram","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001317","descriptor_name":"Austria","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001317","descriptor_name":"Austria","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001317","descriptor_name":"Austria","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004644","descriptor_name":"Emotions","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004644","descriptor_name":"Emotions","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004644","descriptor_name":"Emotions","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007858","descriptor_name":"Learning","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D007858","descriptor_name":"Learning","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D007858","descriptor_name":"Learning","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008137","descriptor_name":"Longitudinal Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008137","descriptor_name":"Longitudinal Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008137","descriptor_name":"Longitudinal Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009473","descriptor_name":"Neuronal Plasticity","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009473","descriptor_name":"Neuronal Plasticity","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009473","descriptor_name":"Neuronal Plasticity","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D011939","descriptor_name":"Mental Recall","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D011939","descriptor_name":"Mental Recall","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D011939","descriptor_name":"Mental Recall","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017367","descriptor_name":"Selective Serotonin Reuptake Inhibitors","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D017367","descriptor_name":"Selective Serotonin Reuptake Inhibitors","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D017367","descriptor_name":"Selective Serotonin Reuptake Inhibitors","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D064368","descriptor_name":"Healthy Volunteers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064368","descriptor_name":"Healthy Volunteers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064368","descriptor_name":"Healthy Volunteers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.neuroimage.2021.118829","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.neuroimage.2021.118829","pdf_url":null,"source":{"id":"https://openalex.org/S103225281","display_name":"NeuroImage","issn_l":"1053-8119","issn":["1053-8119","1095-9572"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroImage","raw_type":"journal-article"},{"id":"pmid:34923134","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34923134","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroImage","raw_type":null},{"id":"pmh:oai:doaj.org/article:ba181d1eb2fd4480bc1856993017dae6","is_oa":true,"landing_page_url":"https://doaj.org/article/ba181d1eb2fd4480bc1856993017dae6","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"NeuroImage, Vol 247, Iss , Pp 118829- (2022)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.neuroimage.2021.118829","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.neuroimage.2021.118829","pdf_url":null,"source":{"id":"https://openalex.org/S103225281","display_name":"NeuroImage","issn_l":"1053-8119","issn":["1053-8119","1095-9572"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroImage","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Quality Education","score":0.7099999785423279,"id":"https://metadata.un.org/sdg/4"}],"awards":[{"id":"https://openalex.org/G4308086504","display_name":"Enhancement of learning associated neural plasticity by SSRIs","funder_award_id":"KLI 516","funder_id":"https://openalex.org/F4320321181","funder_display_name":"Austrian Science Fund"}],"funders":[{"id":"https://openalex.org/F4320321004","display_name":"\u00d6sterreichischen Akademie der Wissenschaften","ror":"https://ror.org/03anc3s24"},{"id":"https://openalex.org/F4320321181","display_name":"Austrian Science Fund","ror":"https://ror.org/013tf3c58"},{"id":"https://openalex.org/F4320321896","display_name":"Bundesministerium f\u00fcr Wissenschaft, Forschung und Wirtschaft","ror":"https://ror.org/02d229b24"},{"id":"https://openalex.org/F4320323437","display_name":"Medizinische Universit\u00e4t Wien","ror":"https://ror.org/05n3x4p02"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":125,"referenced_works":["https://openalex.org/W1144187633","https://openalex.org/W1580587320","https://openalex.org/W1857718762","https://openalex.org/W1873033581","https://openalex.org/W1890188363","https://openalex.org/W1954539306","https://openalex.org/W1965687214","https://openalex.org/W1967112810","https://openalex.org/W1969056589","https://openalex.org/W1974004848","https://openalex.org/W1981220245","https://openalex.org/W1981947265","https://openalex.org/W1983439863","https://openalex.org/W1988394934","https://openalex.org/W1990257603","https://openalex.org/W1991878909","https://openalex.org/W1993699186","https://openalex.org/W1998261300","https://openalex.org/W1999358054","https://openalex.org/W2005238835","https://openalex.org/W2005821483","https://openalex.org/W2011331356","https://openalex.org/W2011826549","https://openalex.org/W2012130547","https://openalex.org/W2014711343","https://openalex.org/W2016953682","https://openalex.org/W2018013323","https://openalex.org/W2020341685","https://openalex.org/W2022386077","https://openalex.org/W2023170665","https://openalex.org/W2024880767","https://openalex.org/W2025221637","https://openalex.org/W2025837747","https://openalex.org/W2030193357","https://openalex.org/W2036499082","https://openalex.org/W2041300466","https://openalex.org/W2041305428","https://openalex.org/W2045477379","https://openalex.org/W2048023678","https://openalex.org/W2050597556","https://openalex.org/W2051423370","https://openalex.org/W2053590082","https://openalex.org/W2055098509","https://openalex.org/W2062190490","https://openalex.org/W2068375947","https://openalex.org/W2069825985","https://openalex.org/W2076256750","https://openalex.org/W2079247946","https://openalex.org/W2080835165","https://openalex.org/W2081232257","https://openalex.org/W2081403337","https://openalex.org/W2082076406","https://openalex.org/W2082627290","https://openalex.org/W2084026951","https://openalex.org/W2084491070","https://openalex.org/W2090687525","https://openalex.org/W2100532211","https://openalex.org/W2102357568","https://openalex.org/W2110259656","https://openalex.org/W2120747195","https://openalex.org/W2120916112","https://openalex.org/W2126520022","https://openalex.org/W2128574243","https://openalex.org/W2132706865","https://openalex.org/W2133188546","https://openalex.org/W2136977056","https://openalex.org/W2137294741","https://openalex.org/W2140172277","https://openalex.org/W2140505555","https://openalex.org/W2140952948","https://openalex.org/W2142420226","https://openalex.org/W2144743430","https://openalex.org/W2150303559","https://openalex.org/W2150575945","https://openalex.org/W2150898751","https://openalex.org/W2153079047","https://openalex.org/W2155197884","https://openalex.org/W2157860693","https://openalex.org/W2158318524","https://openalex.org/W2163417752","https://openalex.org/W2163584510","https://openalex.org/W2179182088","https://openalex.org/W2216515421","https://openalex.org/W2280029686","https://openalex.org/W2341134165","https://openalex.org/W2341558148","https://openalex.org/W2481212679","https://openalex.org/W2502502962","https://openalex.org/W2548205224","https://openalex.org/W2566691114","https://openalex.org/W2568812898","https://openalex.org/W2580637087","https://openalex.org/W2594090197","https://openalex.org/W2601063088","https://openalex.org/W2603032646","https://openalex.org/W2607453530","https://openalex.org/W2624853583","https://openalex.org/W2742590294","https://openalex.org/W2776811182","https://openalex.org/W2792903968","https://openalex.org/W2805363520","https://openalex.org/W2806086832","https://openalex.org/W2885062896","https://openalex.org/W2886772950","https://openalex.org/W2887963549","https://openalex.org/W2916872821","https://openalex.org/W2922472639","https://openalex.org/W2941739682","https://openalex.org/W2946394274","https://openalex.org/W2949605374","https://openalex.org/W2950244299","https://openalex.org/W2972441452","https://openalex.org/W2979375280","https://openalex.org/W2995940920","https://openalex.org/W3044986547","https://openalex.org/W3058958332","https://openalex.org/W3092379787","https://openalex.org/W3092712006","https://openalex.org/W3103204785","https://openalex.org/W3114694909","https://openalex.org/W3132500005","https://openalex.org/W3133534692","https://openalex.org/W3156124518","https://openalex.org/W6639021882","https://openalex.org/W6673203322"],"related_works":["https://openalex.org/W1957941398","https://openalex.org/W2083760741","https://openalex.org/W2136395564","https://openalex.org/W4212839896","https://openalex.org/W3084290198","https://openalex.org/W3145695501","https://openalex.org/W2889675489","https://openalex.org/W2035490907","https://openalex.org/W2020741738","https://openalex.org/W2405220830"],"abstract_inverted_index":{"Learning-induced":[0],"neuroplastic":[1],"changes,":[2],"further":[3],"modulated":[4,139],"by":[5,140],"content":[6,83],"and":[7,113,134,154,159],"setting,":[8],"are":[9],"mirrored":[10],"in":[11,47,56,120,187],"brain":[12],"functional":[13,106],"connectivity":[14,149,161],"(FC).":[15],"In":[16],"animal":[17],"models,":[18],"selective":[19],"serotonin":[20],"reuptake":[21],"inhibitors":[22],"(SSRIs)":[23],"have":[24],"been":[25],"shown":[26],"to":[27,44,74,166],"facilitate":[28],"neuroplasticity.":[29,214],"This":[30],"is":[31],"especially":[32],"prominent":[33],"during":[34],"emotional":[35,65,170],"relearning,":[36,92],"such":[37],"as":[38],"fear":[39],"extinction,":[40],"which":[41],"may":[42],"translate":[43],"clinical":[45,188],"improvements":[46],"patients.":[48],"To":[49],"investigate":[50],"a":[51,96,121],"comparable":[52],"modulation":[53],"of":[54,64,80,99,175,202,209],"neuroplasticity":[55,191],"humans,":[57],"99":[58],"healthy":[59],"subjects":[60,93],"underwent":[61],"three":[62],"weeks":[63],"(matching":[66,71],"faces)":[67],"or":[68,103],"non-emotional":[69,158],"learning":[70],"Chinese":[72],"characters":[73],"unrelated":[75],"German":[76],"nouns).":[77],"Shuffled":[78],"pairings":[79],"the":[81,88,100,115,126,130,147,160,183,200,207],"original":[82],"were":[84,138],"subsequently":[85],"relearned":[86],"for":[87,157,169],"same":[89],"time.":[90],"During":[91],"received":[94],"either":[95],"daily":[97],"dose":[98],"SSRI":[101],"escitalopram":[102,141],"placebo.":[104],"Resting-state":[105],"magnetic":[107],"resonance":[108],"imaging":[109],"was":[110],"performed":[111],"before":[112],"after":[114],"(re-)learning":[116],"phases.":[117],"FC":[118],"changes":[119],"network":[122],"comprising":[123],"Broca's":[124,167],"area,":[125],"medial":[127,151,163],"prefrontal":[128,152,164],"cortex,":[129],"right":[131],"inferior":[132],"temporal":[133],"left":[135],"lingual":[136,155],"gyrus":[137,156],"intake.":[142],"More":[143],"specifically,":[144],"it":[145],"increased":[146],"bidirectional":[148],"between":[150],"cortex":[153,165],"from":[162],"area":[168],"relearning.":[171],"The":[172],"context":[173],"dependence":[174],"these":[176,204],"effects":[177],"together":[178],"with":[179],"behavioral":[180],"correlations":[181],"supports":[182],"assumption":[184],"that":[185],"SSRIs":[186],"practice":[189],"improve":[190],"rather":[192],"than":[193],"psychiatric":[194],"symptoms":[195],"per":[196],"se.":[197],"Beyond":[198],"expanding":[199],"complexities":[201],"learning,":[203],"findings":[205],"emphasize":[206],"influence":[208],"external":[210],"factors":[211],"on":[212],"human":[213]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":6}],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2025-10-10T00:00:00"}