{"id":"https://openalex.org/W3094024356","doi":"https://doi.org/10.1016/j.neuroimage.2020.117491","title":"Whole-brain estimates of directed connectivity for human connectomics","display_name":"Whole-brain estimates of directed connectivity for human connectomics","publication_year":2020,"publication_date":"2020-10-24","ids":{"openalex":"https://openalex.org/W3094024356","doi":"https://doi.org/10.1016/j.neuroimage.2020.117491","mag":"3094024356","pmid":"https://pubmed.ncbi.nlm.nih.gov/33115664"},"language":"en","primary_location":{"id":"doi:10.1016/j.neuroimage.2020.117491","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.neuroimage.2020.117491","pdf_url":null,"source":{"id":"https://openalex.org/S103225281","display_name":"NeuroImage","issn_l":"1053-8119","issn":["1053-8119","1095-9572"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroImage","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1016/j.neuroimage.2020.117491","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084032582","display_name":"Stefan Fr\u00e4ssle","orcid":"https://orcid.org/0000-0002-8011-2226"},"institutions":[{"id":"https://openalex.org/I202697423","display_name":"University of Zurich","ror":"https://ror.org/02crff812","country_code":"CH","type":"education","lineage":["https://openalex.org/I202697423"]},{"id":"https://openalex.org/I35440088","display_name":"ETH Zurich","ror":"https://ror.org/05a28rw58","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088"]},{"id":"https://openalex.org/I4210090941","display_name":"Institute for Biomedical Engineering","ror":"https://ror.org/00baskk38","country_code":"CH","type":"facility","lineage":["https://openalex.org/I202697423","https://openalex.org/I2799323385","https://openalex.org/I35440088","https://openalex.org/I4210090941"]}],"countries":["CH"],"is_corresponding":true,"raw_author_name":"Stefan Fr\u00e4ssle","raw_affiliation_strings":["Translational Neuromodeling Unit (TNU), Institute for Biomedical Engineering, University of Zurich & ETH Zurich, Wilfriedstrasse 6, 8032 Zurich, Switzerland. Electronic address: stefanf@biomed.ee.ethz.ch","Translational Neuromodeling Unit (TNU), Institute for Biomedical Engineering, University of Zurich & ETH Zurich, Wilfriedstrasse 6, 8032 Zurich, Switzerland"],"affiliations":[{"raw_affiliation_string":"Translational Neuromodeling Unit (TNU), Institute for Biomedical Engineering, University of Zurich & ETH Zurich, Wilfriedstrasse 6, 8032 Zurich, Switzerland. Electronic address: stefanf@biomed.ee.ethz.ch","institution_ids":["https://openalex.org/I4210090941"]},{"raw_affiliation_string":"Translational Neuromodeling Unit (TNU), Institute for Biomedical Engineering, University of Zurich & ETH Zurich, Wilfriedstrasse 6, 8032 Zurich, Switzerland","institution_ids":["https://openalex.org/I4210090941","https://openalex.org/I202697423","https://openalex.org/I35440088"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082852878","display_name":"Zina M. Manjaly","orcid":null},"institutions":[{"id":"https://openalex.org/I35440088","display_name":"ETH Zurich","ror":"https://ror.org/05a28rw58","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Zina M. Manjaly","raw_affiliation_strings":["Department of Neurology, Schulthess, 8008 Zurich, Switzerland & Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland"],"affiliations":[{"raw_affiliation_string":"Department of Neurology, Schulthess, 8008 Zurich, Switzerland & Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland","institution_ids":["https://openalex.org/I35440088"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085130243","display_name":"Cao Tri","orcid":"https://orcid.org/0000-0003-1959-9562"},"institutions":[{"id":"https://openalex.org/I202697423","display_name":"University of Zurich","ror":"https://ror.org/02crff812","country_code":"CH","type":"education","lineage":["https://openalex.org/I202697423"]},{"id":"https://openalex.org/I35440088","display_name":"ETH Zurich","ror":"https://ror.org/05a28rw58","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088"]},{"id":"https://openalex.org/I4210090941","display_name":"Institute for Biomedical Engineering","ror":"https://ror.org/00baskk38","country_code":"CH","type":"facility","lineage":["https://openalex.org/I202697423","https://openalex.org/I2799323385","https://openalex.org/I35440088","https://openalex.org/I4210090941"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Cao T. Do","raw_affiliation_strings":["Translational Neuromodeling Unit (TNU), Institute for Biomedical Engineering, University of Zurich & ETH Zurich, Wilfriedstrasse 6, 8032 Zurich, Switzerland"],"affiliations":[{"raw_affiliation_string":"Translational Neuromodeling Unit (TNU), Institute for Biomedical Engineering, University of Zurich & ETH Zurich, Wilfriedstrasse 6, 8032 Zurich, Switzerland","institution_ids":["https://openalex.org/I4210090941","https://openalex.org/I202697423","https://openalex.org/I35440088"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082870988","display_name":"Lars Kasper","orcid":"https://orcid.org/0000-0001-7667-603X"},"institutions":[{"id":"https://openalex.org/I202697423","display_name":"University of Zurich","ror":"https://ror.org/02crff812","country_code":"CH","type":"education","lineage":["https://openalex.org/I202697423"]},{"id":"https://openalex.org/I35440088","display_name":"ETH Zurich","ror":"https://ror.org/05a28rw58","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088"]},{"id":"https://openalex.org/I4210090941","display_name":"Institute for Biomedical Engineering","ror":"https://ror.org/00baskk38","country_code":"CH","type":"facility","lineage":["https://openalex.org/I202697423","https://openalex.org/I2799323385","https://openalex.org/I35440088","https://openalex.org/I4210090941"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Lars Kasper","raw_affiliation_strings":["Translational Neuromodeling Unit (TNU), Institute for Biomedical Engineering, University of Zurich & ETH Zurich, Wilfriedstrasse 6, 8032 Zurich, Switzerland; Institute for Biomedical Engineering, ETH Zurich & University of Zurich, 8092 Zurich, Switzerland","Translational Neuromodeling Unit (TNU), Institute for Biomedical Engineering, University of Zurich & ETH Zurich, Wilfriedstrasse 6, 8032 Zurich, Switzerland","Institute for Biomedical Engineering, ETH Zurich & University of Zurich, 8092 Zurich, Switzerland"],"affiliations":[{"raw_affiliation_string":"Translational Neuromodeling Unit (TNU), Institute for Biomedical Engineering, University of Zurich & ETH Zurich, Wilfriedstrasse 6, 8032 Zurich, Switzerland; Institute for Biomedical Engineering, ETH Zurich & University of Zurich, 8092 Zurich, Switzerland","institution_ids":["https://openalex.org/I4210090941"]},{"raw_affiliation_string":"Translational Neuromodeling Unit (TNU), Institute for Biomedical Engineering, University of Zurich & ETH Zurich, Wilfriedstrasse 6, 8032 Zurich, Switzerland","institution_ids":["https://openalex.org/I4210090941","https://openalex.org/I202697423","https://openalex.org/I35440088"]},{"raw_affiliation_string":"Institute for Biomedical Engineering, ETH Zurich & University of Zurich, 8092 Zurich, Switzerland","institution_ids":["https://openalex.org/I4210090941","https://openalex.org/I202697423","https://openalex.org/I35440088"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089747387","display_name":"Klaas P. Pruessmann","orcid":"https://orcid.org/0000-0003-0009-8362"},"institutions":[{"id":"https://openalex.org/I202697423","display_name":"University of Zurich","ror":"https://ror.org/02crff812","country_code":"CH","type":"education","lineage":["https://openalex.org/I202697423"]},{"id":"https://openalex.org/I35440088","display_name":"ETH Zurich","ror":"https://ror.org/05a28rw58","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088"]},{"id":"https://openalex.org/I4210090941","display_name":"Institute for Biomedical Engineering","ror":"https://ror.org/00baskk38","country_code":"CH","type":"facility","lineage":["https://openalex.org/I202697423","https://openalex.org/I2799323385","https://openalex.org/I35440088","https://openalex.org/I4210090941"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Klaas P. Pruessmann","raw_affiliation_strings":["Institute for Biomedical Engineering, ETH Zurich & University of Zurich, 8092 Zurich, Switzerland"],"affiliations":[{"raw_affiliation_string":"Institute for Biomedical Engineering, ETH Zurich & University of Zurich, 8092 Zurich, Switzerland","institution_ids":["https://openalex.org/I4210090941","https://openalex.org/I202697423","https://openalex.org/I35440088"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5016719332","display_name":"Klaas \u0395. Stephan","orcid":"https://orcid.org/0000-0002-8594-9092"},"institutions":[{"id":"https://openalex.org/I165524941","display_name":"Wellcome Centre for Human Neuroimaging","ror":"https://ror.org/02704qw51","country_code":"GB","type":"facility","lineage":["https://openalex.org/I124357947","https://openalex.org/I165524941","https://openalex.org/I45129253","https://openalex.org/I87048295"]},{"id":"https://openalex.org/I202697423","display_name":"University of Zurich","ror":"https://ror.org/02crff812","country_code":"CH","type":"education","lineage":["https://openalex.org/I202697423"]},{"id":"https://openalex.org/I35440088","display_name":"ETH Zurich","ror":"https://ror.org/05a28rw58","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088"]},{"id":"https://openalex.org/I4210090941","display_name":"Institute for Biomedical Engineering","ror":"https://ror.org/00baskk38","country_code":"CH","type":"facility","lineage":["https://openalex.org/I202697423","https://openalex.org/I2799323385","https://openalex.org/I35440088","https://openalex.org/I4210090941"]},{"id":"https://openalex.org/I4210110850","display_name":"Max Planck Institute for Metabolism Research","ror":"https://ror.org/0199g0r92","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210110850"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["CH","DE","GB"],"is_corresponding":false,"raw_author_name":"Klaas E. Stephan","raw_affiliation_strings":["Translational Neuromodeling Unit (TNU), Institute for Biomedical Engineering, University of Zurich & ETH Zurich, Wilfriedstrasse 6, 8032 Zurich, Switzerland; Wellcome Centre for Human Neuroimaging, University College London, London WC1N 3BG, United Kingdom; Max Planck Institute for Metabolism Research, Cologne, Germany","Max Planck Institute for Metabolism Research, Cologne, Germany","Translational Neuromodeling Unit (TNU), Institute for Biomedical Engineering, University of Zurich & ETH Zurich, Wilfriedstrasse 6, 8032 Zurich, Switzerland","Wellcome Centre for Human Neuroimaging, University College London, London WC1N 3BG, United Kingdom"],"affiliations":[{"raw_affiliation_string":"Translational Neuromodeling Unit (TNU), Institute for Biomedical Engineering, University of Zurich & ETH Zurich, Wilfriedstrasse 6, 8032 Zurich, Switzerland; Wellcome Centre for Human Neuroimaging, University College London, London WC1N 3BG, United Kingdom; Max Planck Institute for Metabolism Research, Cologne, Germany","institution_ids":["https://openalex.org/I165524941","https://openalex.org/I45129253"]},{"raw_affiliation_string":"Max Planck Institute for Metabolism Research, Cologne, Germany","institution_ids":["https://openalex.org/I4210110850"]},{"raw_affiliation_string":"Translational Neuromodeling Unit (TNU), Institute for Biomedical Engineering, University of Zurich & ETH Zurich, Wilfriedstrasse 6, 8032 Zurich, Switzerland","institution_ids":["https://openalex.org/I4210090941","https://openalex.org/I202697423","https://openalex.org/I35440088"]},{"raw_affiliation_string":"Wellcome Centre for Human Neuroimaging, University College London, London WC1N 3BG, United Kingdom","institution_ids":["https://openalex.org/I165524941","https://openalex.org/I45129253"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5084032582"],"corresponding_institution_ids":["https://openalex.org/I202697423","https://openalex.org/I35440088","https://openalex.org/I4210090941"],"apc_list":{"value":3450,"currency":"USD","value_usd":3450},"apc_paid":{"value":3450,"currency":"USD","value_usd":3450},"fwci":2.501,"has_fulltext":false,"cited_by_count":41,"citation_normalized_percentile":{"value":0.89848917,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"225","issue":null,"first_page":"117491","last_page":"117491"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9983999729156494,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.9972000122070312,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/connectomics","display_name":"Connectomics","score":0.9675672054290771},{"id":"https://openalex.org/keywords/connectome","display_name":"Connectome","score":0.7669436931610107},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6712085604667664},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.5229683518409729},{"id":"https://openalex.org/keywords/functional-connectivity","display_name":"Functional connectivity","score":0.5078800320625305},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4814452528953552},{"id":"https://openalex.org/keywords/human-brain","display_name":"Human brain","score":0.4157448410987854},{"id":"https://openalex.org/keywords/graph","display_name":"Graph","score":0.41356319189071655},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.39578261971473694},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.20328277349472046},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.16265875101089478}],"concepts":[{"id":"https://openalex.org/C2779097318","wikidata":"https://www.wikidata.org/wiki/Q2993446","display_name":"Connectomics","level":4,"score":0.9675672054290771},{"id":"https://openalex.org/C45715564","wikidata":"https://www.wikidata.org/wiki/Q1292103","display_name":"Connectome","level":3,"score":0.7669436931610107},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6712085604667664},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5229683518409729},{"id":"https://openalex.org/C3018011982","wikidata":"https://www.wikidata.org/wiki/Q7316120","display_name":"Functional connectivity","level":2,"score":0.5078800320625305},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4814452528953552},{"id":"https://openalex.org/C2777670902","wikidata":"https://www.wikidata.org/wiki/Q492038","display_name":"Human brain","level":2,"score":0.4157448410987854},{"id":"https://openalex.org/C132525143","wikidata":"https://www.wikidata.org/wiki/Q141488","display_name":"Graph","level":2,"score":0.41356319189071655},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.39578261971473694},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.20328277349472046},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.16265875101089478}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009044","descriptor_name":"Motor Cortex","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D009044","descriptor_name":"Motor Cortex","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D009044","descriptor_name":"Motor Cortex","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D009044","descriptor_name":"Motor Cortex","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009044","descriptor_name":"Motor Cortex","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009044","descriptor_name":"Motor Cortex","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009434","descriptor_name":"Neural Pathways","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D009434","descriptor_name":"Neural Pathways","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D009434","descriptor_name":"Neural Pathways","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D009434","descriptor_name":"Neural Pathways","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009434","descriptor_name":"Neural Pathways","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009434","descriptor_name":"Neural Pathways","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D012044","descriptor_name":"Regression Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012044","descriptor_name":"Regression Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012044","descriptor_name":"Regression Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059907","descriptor_name":"Functional Neuroimaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D059907","descriptor_name":"Functional Neuroimaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D059907","descriptor_name":"Functional Neuroimaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D063132","descriptor_name":"Connectome","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D063132","descriptor_name":"Connectome","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D063132","descriptor_name":"Connectome","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.neuroimage.2020.117491","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.neuroimage.2020.117491","pdf_url":null,"source":{"id":"https://openalex.org/S103225281","display_name":"NeuroImage","issn_l":"1053-8119","issn":["1053-8119","1095-9572"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroImage","raw_type":"journal-article"},{"id":"pmid:33115664","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33115664","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroImage","raw_type":null},{"id":"pmh:oai:doaj.org/article:fc00226eefc54b539717bdff6ce67cb6","is_oa":true,"landing_page_url":"https://doaj.org/article/fc00226eefc54b539717bdff6ce67cb6","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"NeuroImage, Vol 225, Iss , Pp 117491- (2021)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.neuroimage.2020.117491","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.neuroimage.2020.117491","pdf_url":null,"source":{"id":"https://openalex.org/S103225281","display_name":"NeuroImage","issn_l":"1053-8119","issn":["1053-8119","1095-9572"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroImage","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G415830993","display_name":null,"funder_award_id":"320030_179377","funder_id":"https://openalex.org/F4320320924","funder_display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320320924","display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung","ror":"https://ror.org/00yjd3n13"},{"id":"https://openalex.org/F4320321652","display_name":"Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich","ror":"https://ror.org/05a28rw58"},{"id":"https://openalex.org/F4320323874","display_name":"Universit\u00e4t Z\u00fcrich","ror":"https://ror.org/02crff812"},{"id":"https://openalex.org/F4320329329","display_name":"Ren\u00e9 und Susanne Braginsky Stiftung","ror":"https://ror.org/00gcc2a38"},{"id":"https://openalex.org/F4320338368","display_name":"FP7 People: Marie-Curie Actions","ror":"https://ror.org/00k4n6c32"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":117,"referenced_works":["https://openalex.org/W1496870175","https://openalex.org/W1663973292","https://openalex.org/W1756616509","https://openalex.org/W1785570092","https://openalex.org/W1828334443","https://openalex.org/W1849775727","https://openalex.org/W1967225040","https://openalex.org/W1969533226","https://openalex.org/W1971937094","https://openalex.org/W1975700187","https://openalex.org/W1983451956","https://openalex.org/W1989621138","https://openalex.org/W1991212384","https://openalex.org/W1991421001","https://openalex.org/W1994341528","https://openalex.org/W1998679999","https://openalex.org/W1999359258","https://openalex.org/W1999653836","https://openalex.org/W2000619457","https://openalex.org/W2003510068","https://openalex.org/W2004026511","https://openalex.org/W2005821483","https://openalex.org/W2005933475","https://openalex.org/W2006850368","https://openalex.org/W2007683591","https://openalex.org/W2014022174","https://openalex.org/W2015877124","https://openalex.org/W2021768951","https://openalex.org/W2022424636","https://openalex.org/W2022802424","https://openalex.org/W2024729467","https://openalex.org/W2028343350","https://openalex.org/W2028722600","https://openalex.org/W2031279517","https://openalex.org/W2032038095","https://openalex.org/W2033802416","https://openalex.org/W2039522025","https://openalex.org/W2044829843","https://openalex.org/W2047219509","https://openalex.org/W2049683591","https://openalex.org/W2052305018","https://openalex.org/W2052318178","https://openalex.org/W2058046532","https://openalex.org/W2061564920","https://openalex.org/W2063497316","https://openalex.org/W2064979714","https://openalex.org/W2066439376","https://openalex.org/W2078856647","https://openalex.org/W2079095593","https://openalex.org/W2080403608","https://openalex.org/W2095651675","https://openalex.org/W2098580305","https://openalex.org/W2100235615","https://openalex.org/W2107334756","https://openalex.org/W2109198067","https://openalex.org/W2110000143","https://openalex.org/W2111613011","https://openalex.org/W2112497174","https://openalex.org/W2113003488","https://openalex.org/W2113191728","https://openalex.org/W2113257799","https://openalex.org/W2117663940","https://openalex.org/W2120836547","https://openalex.org/W2124496726","https://openalex.org/W2131729872","https://openalex.org/W2132555912","https://openalex.org/W2135173838","https://openalex.org/W2138905229","https://openalex.org/W2142808602","https://openalex.org/W2146052710","https://openalex.org/W2146406922","https://openalex.org/W2146693559","https://openalex.org/W2147933447","https://openalex.org/W2148773858","https://openalex.org/W2149153247","https://openalex.org/W2160938187","https://openalex.org/W2161460637","https://openalex.org/W2165117638","https://openalex.org/W2167822639","https://openalex.org/W2167826316","https://openalex.org/W2170418363","https://openalex.org/W2170797424","https://openalex.org/W2171707538","https://openalex.org/W2319534434","https://openalex.org/W2402346616","https://openalex.org/W2412777302","https://openalex.org/W2483809583","https://openalex.org/W2498492890","https://openalex.org/W2499800833","https://openalex.org/W2556623269","https://openalex.org/W2557632452","https://openalex.org/W2594366375","https://openalex.org/W2616940960","https://openalex.org/W2763238765","https://openalex.org/W2789080071","https://openalex.org/W2803973828","https://openalex.org/W2805346424","https://openalex.org/W2805998310","https://openalex.org/W2896587207","https://openalex.org/W2897006304","https://openalex.org/W2901128139","https://openalex.org/W2909745138","https://openalex.org/W2949123561","https://openalex.org/W2949553675","https://openalex.org/W2950254084","https://openalex.org/W2951582858","https://openalex.org/W2963582879","https://openalex.org/W2992870756","https://openalex.org/W3037579089","https://openalex.org/W4205563404","https://openalex.org/W4211091012","https://openalex.org/W4285719527","https://openalex.org/W6629510986","https://openalex.org/W6629634573","https://openalex.org/W6669910087","https://openalex.org/W6676728171","https://openalex.org/W6758093497"],"related_works":["https://openalex.org/W3210800206","https://openalex.org/W1744057168","https://openalex.org/W2124698428","https://openalex.org/W2091472861","https://openalex.org/W2945607120","https://openalex.org/W2086448982","https://openalex.org/W112425480","https://openalex.org/W2550381304","https://openalex.org/W2946138627","https://openalex.org/W3112117434"],"abstract_inverted_index":{"Connectomics":[0],"is":[1,24,35],"essential":[2],"for":[3,38,143],"understanding":[4],"large-scale":[5],"brain":[6,22],"networks":[7,138],"but":[8],"requires":[9],"that":[10,25,78],"individual":[11],"connection":[12],"estimates":[13,48,55,104],"are":[14,31,49,60],"neurobiologically":[15],"interpretable.":[16],"In":[17],"particular,":[18],"a":[19,36,71,79,89],"principle":[20],"of":[21,56,101,108,132],"organization":[23],"reciprocal":[26],"connections":[27,135],"between":[28],"cortical":[29],"areas":[30,110],"functionally":[32],"asymmetric.":[33],"This":[34],"challenge":[37],"fMRI-based":[39],"connectomics":[40],"in":[41,88,124,136],"humans":[42],"where":[43],"only":[44],"undirected":[45,114],"functional":[46,106,115],"connectivity":[47,59,86,103,116],"routinely":[50],"available.":[51],"By":[52],"contrast,":[53],"whole-brain":[54,90,137],"effective":[57],"(directed)":[58],"computationally":[61],"challenging,":[62],"and":[63,139],"emerging":[64],"methods":[65],"require":[66],"empirical":[67],"validation.":[68],"Here,":[69],"using":[70],"motor":[72,109],"task":[73],"at":[74],"7T,":[75],"we":[76],"demonstrate":[77,129],"novel":[80],"generative":[81],"model":[82],"can":[83,121],"infer":[84],"known":[85],"features":[87],"network":[91],"(>200":[92],"regions,":[93],">40,000":[94],"connections)":[95],"highly":[96],"efficiently.":[97],"Furthermore,":[98],"graph-theoretical":[99],"analyses":[100],"directed":[102,134],"identify":[105],"roles":[107],"more":[111],"accurately":[112],"than":[113],"estimates.":[117],"These":[118],"results,":[119],"which":[120],"be":[122],"achieved":[123],"an":[125],"entirely":[126],"unsupervised":[127],"manner,":[128],"the":[130],"feasibility":[131],"inferring":[133],"open":[140],"new":[141],"avenues":[142],"human":[144],"connectomics.":[145]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":9},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":1}],"updated_date":"2026-04-09T08:11:56.329763","created_date":"2025-10-10T00:00:00"}