{"id":"https://openalex.org/W2914530927","doi":"https://doi.org/10.1016/j.neuroimage.2019.01.052","title":"Clinical associations of T2-weighted lesion load and lesion location in small vessel disease: Insights from a large prospective cohort study","display_name":"Clinical associations of T2-weighted lesion load and lesion location in small vessel disease: Insights from a large prospective cohort study","publication_year":2019,"publication_date":"2019-01-25","ids":{"openalex":"https://openalex.org/W2914530927","doi":"https://doi.org/10.1016/j.neuroimage.2019.01.052","mag":"2914530927","pmid":"https://pubmed.ncbi.nlm.nih.gov/30685330"},"language":"en","primary_location":{"id":"doi:10.1016/j.neuroimage.2019.01.052","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.neuroimage.2019.01.052","pdf_url":null,"source":{"id":"https://openalex.org/S103225281","display_name":"NeuroImage","issn_l":"1053-8119","issn":["1053-8119","1095-9572"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroImage","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102976276","display_name":"Anna Altermatt","orcid":"https://orcid.org/0000-0001-6397-0758"},"institutions":[{"id":"https://openalex.org/I1850255","display_name":"University of Basel","ror":"https://ror.org/02s6k3f65","country_code":"CH","type":"education","lineage":["https://openalex.org/I1850255"]}],"countries":["CH"],"is_corresponding":true,"raw_author_name":"Anna Altermatt","raw_affiliation_strings":["Department of Biomedical Engineering, University of Basel, Gewerbestrasse 14, 4123, Allschwil, Switzerland; Medical Image Analysis Center (MIAC) AG, Marktgasse 8, 4051, Basel, Switzerland. Electronic address: anna.altermatt@miac.ch","Medical Image Analysis Center (MIAC) AG, Marktgasse 8, 4051, Basel, Switzerland","Department of Biomedical Engineering, University of Basel, Gewerbestrasse 14, 4123, Allschwil, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, University of Basel, Gewerbestrasse 14, 4123, Allschwil, Switzerland; Medical Image Analysis Center (MIAC) AG, Marktgasse 8, 4051, Basel, Switzerland. Electronic address: anna.altermatt@miac.ch","institution_ids":[]},{"raw_affiliation_string":"Medical Image Analysis Center (MIAC) AG, Marktgasse 8, 4051, Basel, Switzerland","institution_ids":[]},{"raw_affiliation_string":"Department of Biomedical Engineering, University of Basel, Gewerbestrasse 14, 4123, Allschwil, Switzerland","institution_ids":["https://openalex.org/I1850255"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057710841","display_name":"Laura Gaetano","orcid":"https://orcid.org/0000-0002-5214-2858"},"institutions":[{"id":"https://openalex.org/I2802542264","display_name":"University Hospital of Basel","ror":"https://ror.org/04k51q396","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2802542264"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Laura Gaetano","raw_affiliation_strings":["Medical Image Analysis Center (MIAC) AG, Marktgasse 8, 4051, Basel, Switzerland; Department of Neurology, University Hospital of Basel, Petersgraben 4, 4031, Basel, Switzerland","Department of Neurology, University Hospital of Basel, Petersgraben 4, 4031, Basel, Switzerland","Medical Image Analysis Center (MIAC) AG, Marktgasse 8, 4051, Basel, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Image Analysis Center (MIAC) AG, Marktgasse 8, 4051, Basel, Switzerland; Department of Neurology, University Hospital of Basel, Petersgraben 4, 4031, Basel, Switzerland","institution_ids":[]},{"raw_affiliation_string":"Department of Neurology, University Hospital of Basel, Petersgraben 4, 4031, Basel, Switzerland","institution_ids":["https://openalex.org/I2802542264"]},{"raw_affiliation_string":"Medical Image Analysis Center (MIAC) AG, Marktgasse 8, 4051, Basel, Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029801040","display_name":"Stefano Magon","orcid":"https://orcid.org/0000-0003-1517-7581"},"institutions":[{"id":"https://openalex.org/I2802542264","display_name":"University Hospital of Basel","ror":"https://ror.org/04k51q396","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2802542264"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Stefano Magon","raw_affiliation_strings":["Medical Image Analysis Center (MIAC) AG, Marktgasse 8, 4051, Basel, Switzerland; Department of Neurology, University Hospital of Basel, Petersgraben 4, 4031, Basel, Switzerland","Department of Neurology, University Hospital of Basel, Petersgraben 4, 4031, Basel, Switzerland","Medical Image Analysis Center (MIAC) AG, Marktgasse 8, 4051, Basel, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Image Analysis Center (MIAC) AG, Marktgasse 8, 4051, Basel, Switzerland; Department of Neurology, University Hospital of Basel, Petersgraben 4, 4031, Basel, Switzerland","institution_ids":[]},{"raw_affiliation_string":"Department of Neurology, University Hospital of Basel, Petersgraben 4, 4031, Basel, Switzerland","institution_ids":["https://openalex.org/I2802542264"]},{"raw_affiliation_string":"Medical Image Analysis Center (MIAC) AG, Marktgasse 8, 4051, Basel, Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063441908","display_name":"Lorena Bauer","orcid":null},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Lorena Bauer","raw_affiliation_strings":["Medical Image Analysis Center (MIAC) AG, Marktgasse 8, 4051, Basel, Switzerland; Department of Neurology, Technische Universit\u00e4t M\u00fcnchen, Ismaningerstrasse 22, 81675, Muenchen, Germany","Department of Neurology, Technische Universit\u00e4t M\u00fcnchen, Ismaningerstrasse 22, 81675, Muenchen, Germany","Medical Image Analysis Center (MIAC) AG, Marktgasse 8, 4051, Basel, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Image Analysis Center (MIAC) AG, Marktgasse 8, 4051, Basel, Switzerland; Department of Neurology, Technische Universit\u00e4t M\u00fcnchen, Ismaningerstrasse 22, 81675, Muenchen, Germany","institution_ids":[]},{"raw_affiliation_string":"Department of Neurology, Technische Universit\u00e4t M\u00fcnchen, Ismaningerstrasse 22, 81675, Muenchen, Germany","institution_ids":["https://openalex.org/I62916508"]},{"raw_affiliation_string":"Medical Image Analysis Center (MIAC) AG, Marktgasse 8, 4051, Basel, Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032706839","display_name":"Regina Feurer","orcid":null},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Regina Feurer","raw_affiliation_strings":["Department of Neurology, Technische Universit\u00e4t M\u00fcnchen, Ismaningerstrasse 22, 81675, Muenchen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Technische Universit\u00e4t M\u00fcnchen, Ismaningerstrasse 22, 81675, Muenchen, Germany","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053722164","display_name":"Hans Gnahn","orcid":null},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Hans Gnahn","raw_affiliation_strings":["Department of Neurology, Technische Universit\u00e4t M\u00fcnchen, Ismaningerstrasse 22, 81675, Muenchen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Technische Universit\u00e4t M\u00fcnchen, Ismaningerstrasse 22, 81675, Muenchen, Germany","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088086785","display_name":"Julia Hartmann","orcid":null},"institutions":[{"id":"https://openalex.org/I4210090473","display_name":"INVADE Institut f\u00fcr Versorgungsforschung","ror":"https://ror.org/00dhqzt16","country_code":"DE","type":"nonprofit","lineage":["https://openalex.org/I4210090473"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Julia Hartmann","raw_affiliation_strings":["INVADE study group, INVADE e.V., Institut f\u00fcr Versorgungsforschung, Karl-B\u00f6hm-Strasse 32, 85598, Baldham, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"INVADE study group, INVADE e.V., Institut f\u00fcr Versorgungsforschung, Karl-B\u00f6hm-Strasse 32, 85598, Baldham, Germany","institution_ids":["https://openalex.org/I4210090473"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109140625","display_name":"Christian Seifert","orcid":null},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Christian L. Seifert","raw_affiliation_strings":["Department of Neurology, Technische Universit\u00e4t M\u00fcnchen, Ismaningerstrasse 22, 81675, Muenchen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Technische Universit\u00e4t M\u00fcnchen, Ismaningerstrasse 22, 81675, Muenchen, Germany","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062090733","display_name":"Holger Poppert","orcid":"https://orcid.org/0000-0003-2189-7681"},"institutions":[{"id":"https://openalex.org/I2800878633","display_name":"Helios Dr. Horst Schmidt Kliniken Wiesbaden","ror":"https://ror.org/03kxagd85","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2800878633","https://openalex.org/I4210138940"]},{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Holger Poppert","raw_affiliation_strings":["Department of Neurology, Technische Universit\u00e4t M\u00fcnchen, Ismaningerstrasse 22, 81675, Muenchen, Germany; Department of Neurology, Helios Dr. Horst Schmidt Kliniken Wiesbaden, Ludwig-Erhard-Strasse 100, 65199, Wiesbaden, Germany","Department of Neurology, Technische Universit\u00e4t M\u00fcnchen, Ismaningerstrasse 22, 81675, Muenchen, Germany","Department of Neurology, Helios Dr. Horst Schmidt Kliniken Wiesbaden, Ludwig-Erhard-Strasse 100, 65199, Wiesbaden, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Technische Universit\u00e4t M\u00fcnchen, Ismaningerstrasse 22, 81675, Muenchen, Germany; Department of Neurology, Helios Dr. Horst Schmidt Kliniken Wiesbaden, Ludwig-Erhard-Strasse 100, 65199, Wiesbaden, Germany","institution_ids":[]},{"raw_affiliation_string":"Department of Neurology, Technische Universit\u00e4t M\u00fcnchen, Ismaningerstrasse 22, 81675, Muenchen, Germany","institution_ids":["https://openalex.org/I62916508"]},{"raw_affiliation_string":"Department of Neurology, Helios Dr. Horst Schmidt Kliniken Wiesbaden, Ludwig-Erhard-Strasse 100, 65199, Wiesbaden, Germany","institution_ids":["https://openalex.org/I2800878633"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049769160","display_name":"Jens Wuerfel","orcid":"https://orcid.org/0000-0002-0034-8053"},"institutions":[{"id":"https://openalex.org/I1850255","display_name":"University of Basel","ror":"https://ror.org/02s6k3f65","country_code":"CH","type":"education","lineage":["https://openalex.org/I1850255"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Jens Wuerfel","raw_affiliation_strings":["Department of Biomedical Engineering, University of Basel, Gewerbestrasse 14, 4123, Allschwil, Switzerland; Medical Image Analysis Center (MIAC) AG, Marktgasse 8, 4051, Basel, Switzerland","Department of Biomedical Engineering, University of Basel, Gewerbestrasse 14, 4123, Allschwil, Switzerland","Medical Image Analysis Center (MIAC) AG, Marktgasse 8, 4051, Basel, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, University of Basel, Gewerbestrasse 14, 4123, Allschwil, Switzerland; Medical Image Analysis Center (MIAC) AG, Marktgasse 8, 4051, Basel, Switzerland","institution_ids":[]},{"raw_affiliation_string":"Department of Biomedical Engineering, University of Basel, Gewerbestrasse 14, 4123, Allschwil, Switzerland","institution_ids":["https://openalex.org/I1850255"]},{"raw_affiliation_string":"Medical Image Analysis Center (MIAC) AG, Marktgasse 8, 4051, Basel, Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056248102","display_name":"Ernst\u2010Wilhelm Radue","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ernst-Wilhelm Radue","raw_affiliation_strings":["Biomedical Research and Education GmbH, Mittlere Strasse 83, 4031, Basel, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Research and Education GmbH, Mittlere Strasse 83, 4031, Basel, Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054874316","display_name":"Ludwig Kappos","orcid":"https://orcid.org/0000-0003-4175-5509"},"institutions":[{"id":"https://openalex.org/I1850255","display_name":"University of Basel","ror":"https://ror.org/02s6k3f65","country_code":"CH","type":"education","lineage":["https://openalex.org/I1850255"]},{"id":"https://openalex.org/I2802542264","display_name":"University Hospital of Basel","ror":"https://ror.org/04k51q396","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2802542264"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Ludwig Kappos","raw_affiliation_strings":["Department of Biomedical Engineering, University of Basel, Gewerbestrasse 14, 4123, Allschwil, Switzerland; Department of Neurology, University Hospital of Basel, Petersgraben 4, 4031, Basel, Switzerland","Department of Neurology, University Hospital of Basel, Petersgraben 4, 4031, Basel, Switzerland","Department of Biomedical Engineering, University of Basel, Gewerbestrasse 14, 4123, Allschwil, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, University of Basel, Gewerbestrasse 14, 4123, Allschwil, Switzerland; Department of Neurology, University Hospital of Basel, Petersgraben 4, 4031, Basel, Switzerland","institution_ids":[]},{"raw_affiliation_string":"Department of Neurology, University Hospital of Basel, Petersgraben 4, 4031, Basel, Switzerland","institution_ids":["https://openalex.org/I2802542264"]},{"raw_affiliation_string":"Department of Biomedical Engineering, University of Basel, Gewerbestrasse 14, 4123, Allschwil, Switzerland","institution_ids":["https://openalex.org/I1850255"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5051313308","display_name":"Till Sprenger","orcid":"https://orcid.org/0000-0002-5390-819X"},"institutions":[{"id":"https://openalex.org/I2802542264","display_name":"University Hospital of Basel","ror":"https://ror.org/04k51q396","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2802542264"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Till Sprenger","raw_affiliation_strings":["Department of Neurology, University Hospital of Basel, Petersgraben 4, 4031, Basel, Switzerland; Department of Neurology, DKD Helios Klinik Wiesbaden, Aukammallee 33, 65191, Wiesbaden, Germany","Department of Neurology, University Hospital of Basel, Petersgraben 4, 4031, Basel, Switzerland","Department of Neurology, DKD Helios Klinik Wiesbaden, Aukammallee 33, 65191, Wiesbaden, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, University Hospital of Basel, Petersgraben 4, 4031, Basel, Switzerland; Department of Neurology, DKD Helios Klinik Wiesbaden, Aukammallee 33, 65191, Wiesbaden, Germany","institution_ids":[]},{"raw_affiliation_string":"Department of Neurology, University Hospital of Basel, Petersgraben 4, 4031, Basel, Switzerland","institution_ids":["https://openalex.org/I2802542264"]},{"raw_affiliation_string":"Department of Neurology, DKD Helios Klinik Wiesbaden, Aukammallee 33, 65191, Wiesbaden, Germany","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":13,"corresponding_author_ids":["https://openalex.org/A5102976276"],"corresponding_institution_ids":["https://openalex.org/I1850255"],"apc_list":{"value":3450,"currency":"USD","value_usd":3450},"apc_paid":null,"fwci":1.7638,"has_fulltext":false,"cited_by_count":23,"citation_normalized_percentile":{"value":0.8333376,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"189","issue":null,"first_page":"727","last_page":"733"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.6829000115394592,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.6829000115394592,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10816","display_name":"Cerebrovascular and Carotid Artery Diseases","score":0.227400004863739,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14144","display_name":"Neurological Disease Mechanisms and Treatments","score":0.020999999716877937,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.7259168028831482},{"id":"https://openalex.org/keywords/hyperintensity","display_name":"Hyperintensity","score":0.7163116335868835},{"id":"https://openalex.org/keywords/dementia","display_name":"Dementia","score":0.5988990068435669},{"id":"https://openalex.org/keywords/cohort","display_name":"Cohort","score":0.5898562073707581},{"id":"https://openalex.org/keywords/lesion","display_name":"Lesion","score":0.5731122493743896},{"id":"https://openalex.org/keywords/cardiology","display_name":"Cardiology","score":0.4744197726249695},{"id":"https://openalex.org/keywords/stroke","display_name":"Stroke (engine)","score":0.43484094738960266},{"id":"https://openalex.org/keywords/white-matter","display_name":"White matter","score":0.4299498200416565},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.4291543662548065},{"id":"https://openalex.org/keywords/prospective-cohort-study","display_name":"Prospective cohort study","score":0.41913753747940063},{"id":"https://openalex.org/keywords/neuroradiology","display_name":"Neuroradiology","score":0.41227084398269653},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.32160335779190063},{"id":"https://openalex.org/keywords/surgery","display_name":"Surgery","score":0.3050321936607361},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"Magnetic resonance imaging","score":0.28949153423309326},{"id":"https://openalex.org/keywords/neurology","display_name":"Neurology","score":0.2504864037036896},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.22005176544189453},{"id":"https://openalex.org/keywords/psychiatry","display_name":"Psychiatry","score":0.12391677498817444}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7259168028831482},{"id":"https://openalex.org/C146638467","wikidata":"https://www.wikidata.org/wiki/Q10529587","display_name":"Hyperintensity","level":3,"score":0.7163116335868835},{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.5988990068435669},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.5898562073707581},{"id":"https://openalex.org/C2781156865","wikidata":"https://www.wikidata.org/wiki/Q827023","display_name":"Lesion","level":2,"score":0.5731122493743896},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.4744197726249695},{"id":"https://openalex.org/C2780645631","wikidata":"https://www.wikidata.org/wiki/Q671554","display_name":"Stroke (engine)","level":2,"score":0.43484094738960266},{"id":"https://openalex.org/C2781192897","wikidata":"https://www.wikidata.org/wiki/Q822050","display_name":"White matter","level":3,"score":0.4299498200416565},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4291543662548065},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.41913753747940063},{"id":"https://openalex.org/C2779889316","wikidata":"https://www.wikidata.org/wiki/Q642836","display_name":"Neuroradiology","level":3,"score":0.41227084398269653},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.32160335779190063},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3050321936607361},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.28949153423309326},{"id":"https://openalex.org/C16568411","wikidata":"https://www.wikidata.org/wiki/Q83042","display_name":"Neurology","level":2,"score":0.2504864037036896},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.22005176544189453},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.12391677498817444},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059345","descriptor_name":"Cerebral Small Vessel Diseases","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D059345","descriptor_name":"Cerebral Small Vessel Diseases","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D059345","descriptor_name":"Cerebral Small Vessel Diseases","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D059345","descriptor_name":"Cerebral Small Vessel Diseases","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D059345","descriptor_name":"Cerebral Small Vessel Diseases","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D059345","descriptor_name":"Cerebral Small Vessel Diseases","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D059345","descriptor_name":"Cerebral Small Vessel Diseases","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D059345","descriptor_name":"Cerebral Small Vessel Diseases","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D059345","descriptor_name":"Cerebral Small Vessel Diseases","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D059345","descriptor_name":"Cerebral Small Vessel Diseases","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D059345","descriptor_name":"Cerebral Small Vessel Diseases","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D059345","descriptor_name":"Cerebral Small Vessel Diseases","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D059906","descriptor_name":"Neuroimaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D059906","descriptor_name":"Neuroimaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D059906","descriptor_name":"Neuroimaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D060825","descriptor_name":"Cognitive Dysfunction","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D060825","descriptor_name":"Cognitive Dysfunction","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D060825","descriptor_name":"Cognitive Dysfunction","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D060825","descriptor_name":"Cognitive Dysfunction","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D060825","descriptor_name":"Cognitive Dysfunction","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D060825","descriptor_name":"Cognitive Dysfunction","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D060825","descriptor_name":"Cognitive Dysfunction","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D060825","descriptor_name":"Cognitive Dysfunction","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D060825","descriptor_name":"Cognitive Dysfunction","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D066127","descriptor_name":"White Matter","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D066127","descriptor_name":"White Matter","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D066127","descriptor_name":"White Matter","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D066127","descriptor_name":"White Matter","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D066127","descriptor_name":"White Matter","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D066127","descriptor_name":"White Matter","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.neuroimage.2019.01.052","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.neuroimage.2019.01.052","pdf_url":null,"source":{"id":"https://openalex.org/S103225281","display_name":"NeuroImage","issn_l":"1053-8119","issn":["1053-8119","1095-9572"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroImage","raw_type":"journal-article"},{"id":"pmid:30685330","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30685330","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroImage","raw_type":null},{"id":"pmh:oai:mediatum.ub.tum.de:node/1589591","is_oa":false,"landing_page_url":"https://mediatum.ub.tum.de/1589591","pdf_url":null,"source":{"id":"https://openalex.org/S4377196330","display_name":"mediaTUM  (Technical University of Munich)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I62916508","host_organization_name":"Technical University of Munich","host_organization_lineage":["https://openalex.org/I62916508"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8600000143051147,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320327734","display_name":"Deutsche Stiftung Neurologie","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W313854285","https://openalex.org/W1522038827","https://openalex.org/W1573234480","https://openalex.org/W1829276549","https://openalex.org/W2034822458","https://openalex.org/W2052644075","https://openalex.org/W2054180055","https://openalex.org/W2054389497","https://openalex.org/W2064722635","https://openalex.org/W2071881327","https://openalex.org/W2082801199","https://openalex.org/W2089435027","https://openalex.org/W2097197306","https://openalex.org/W2100809123","https://openalex.org/W2114293191","https://openalex.org/W2123589765","https://openalex.org/W2130641904","https://openalex.org/W2132874104","https://openalex.org/W2139748910","https://openalex.org/W2143783309","https://openalex.org/W2143895814","https://openalex.org/W2145034992","https://openalex.org/W2148726987","https://openalex.org/W2153857579","https://openalex.org/W2156387203","https://openalex.org/W2158742097","https://openalex.org/W2158766477","https://openalex.org/W2159122349","https://openalex.org/W2169452761","https://openalex.org/W2527609605","https://openalex.org/W2573536041","https://openalex.org/W2586365808","https://openalex.org/W2604605434","https://openalex.org/W2763429356","https://openalex.org/W2768007735","https://openalex.org/W2791577590","https://openalex.org/W2805224440","https://openalex.org/W3192373659","https://openalex.org/W4235770099","https://openalex.org/W4242721106","https://openalex.org/W6663956422","https://openalex.org/W6745361047"],"related_works":["https://openalex.org/W2417916121","https://openalex.org/W4253904327","https://openalex.org/W4238317426","https://openalex.org/W2090103820","https://openalex.org/W4241681448","https://openalex.org/W2011391747","https://openalex.org/W2409059799","https://openalex.org/W3092209499","https://openalex.org/W2101112453","https://openalex.org/W2334440116"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":4}],"updated_date":"2026-04-29T09:16:38.111599","created_date":"2025-10-10T00:00:00"}