{"id":"https://openalex.org/W2800657613","doi":"https://doi.org/10.1016/j.neuroimage.2018.04.054","title":"Regional brain volume changes following chronic antipsychotic administration are mediated by the dopamine D2 receptor","display_name":"Regional brain volume changes following chronic antipsychotic administration are mediated by the dopamine D2 receptor","publication_year":2018,"publication_date":"2018-04-26","ids":{"openalex":"https://openalex.org/W2800657613","doi":"https://doi.org/10.1016/j.neuroimage.2018.04.054","mag":"2800657613","pmid":"https://pubmed.ncbi.nlm.nih.gov/29704613"},"language":"en","primary_location":{"id":"doi:10.1016/j.neuroimage.2018.04.054","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.neuroimage.2018.04.054","pdf_url":null,"source":{"id":"https://openalex.org/S103225281","display_name":"NeuroImage","issn_l":"1053-8119","issn":["1053-8119","1095-9572"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroImage","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034368203","display_name":"Elisa Guma","orcid":"https://orcid.org/0000-0003-4651-8529"},"institutions":[{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]},{"id":"https://openalex.org/I2799434747","display_name":"Douglas Mental Health University Institute","ror":"https://ror.org/05dk2r620","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2799434747"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Elisa Guma","raw_affiliation_strings":["Department of Psychiatry & Integrated Program in Neuroscience, McGill University, 845 Sherbrooke St W, Montreal, QC, H3A 0G4 Canada; Cerebral Imaging Center, Douglas Mental Health University Institute, Verdun, Quebec, H4H 1R3, Canada","Cerebral Imaging Center, Douglas Mental Health University Institute, Verdun, Quebec, H4H 1R3, Canada","Department of Psychiatry & Integrated Program in Neuroscience, McGill University, 845 Sherbrooke St W, Montreal, QC, H3A 0G4 Canada"],"affiliations":[{"raw_affiliation_string":"Department of Psychiatry & Integrated Program in Neuroscience, McGill University, 845 Sherbrooke St W, Montreal, QC, H3A 0G4 Canada; Cerebral Imaging Center, Douglas Mental Health University Institute, Verdun, Quebec, H4H 1R3, Canada","institution_ids":[]},{"raw_affiliation_string":"Cerebral Imaging Center, Douglas Mental Health University Institute, Verdun, Quebec, H4H 1R3, Canada","institution_ids":["https://openalex.org/I2799434747"]},{"raw_affiliation_string":"Department of Psychiatry & Integrated Program in Neuroscience, McGill University, 845 Sherbrooke St W, Montreal, QC, H3A 0G4 Canada","institution_ids":["https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032737960","display_name":"Jill Rocchetti","orcid":"https://orcid.org/0000-0002-1220-2772"},"institutions":[{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Jill Rocchetti","raw_affiliation_strings":["Department of Psychiatry & Integrated Program in Neuroscience, McGill University, 845 Sherbrooke St W, Montreal, QC, H3A 0G4 Canada"],"affiliations":[{"raw_affiliation_string":"Department of Psychiatry & Integrated Program in Neuroscience, McGill University, 845 Sherbrooke St W, Montreal, QC, H3A 0G4 Canada","institution_ids":["https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029207426","display_name":"Gabriel A. Devenyi","orcid":"https://orcid.org/0000-0002-7766-1187"},"institutions":[{"id":"https://openalex.org/I2799434747","display_name":"Douglas Mental Health University Institute","ror":"https://ror.org/05dk2r620","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2799434747"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Gabriel A. Devenyi","raw_affiliation_strings":["Cerebral Imaging Center, Douglas Mental Health University Institute, Verdun, Quebec, H4H 1R3, Canada"],"affiliations":[{"raw_affiliation_string":"Cerebral Imaging Center, Douglas Mental Health University Institute, Verdun, Quebec, H4H 1R3, Canada","institution_ids":["https://openalex.org/I2799434747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028137500","display_name":"Arnaud Tanti","orcid":"https://orcid.org/0000-0003-4249-2317"},"institutions":[{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]},{"id":"https://openalex.org/I2799434747","display_name":"Douglas Mental Health University Institute","ror":"https://ror.org/05dk2r620","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2799434747"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Arnaud Tanti","raw_affiliation_strings":["McGill Group for Suicide Studies, Department of Psychiatry, McGill University, Douglas Mental Health University Institute, Montreal, QC, Canada"],"affiliations":[{"raw_affiliation_string":"McGill Group for Suicide Studies, Department of Psychiatry, McGill University, Douglas Mental Health University Institute, Montreal, QC, Canada","institution_ids":["https://openalex.org/I2799434747","https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112291074","display_name":"Axel Mathieu","orcid":null},"institutions":[{"id":"https://openalex.org/I2799434747","display_name":"Douglas Mental Health University Institute","ror":"https://ror.org/05dk2r620","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2799434747"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Axel Mathieu","raw_affiliation_strings":["Cerebral Imaging Center, Douglas Mental Health University Institute, Verdun, Quebec, H4H 1R3, Canada"],"affiliations":[{"raw_affiliation_string":"Cerebral Imaging Center, Douglas Mental Health University Institute, Verdun, Quebec, H4H 1R3, Canada","institution_ids":["https://openalex.org/I2799434747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058105019","display_name":"Jason P. Lerch","orcid":"https://orcid.org/0000-0002-4871-8578"},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I2801317318","display_name":"Hospital for Sick Children","ror":"https://ror.org/057q4rt57","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801317318"]},{"id":"https://openalex.org/I4210141030","display_name":"SickKids Foundation","ror":"https://ror.org/04374qe70","country_code":"CA","type":"funder","lineage":["https://openalex.org/I4210141030"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Jason P. Lerch","raw_affiliation_strings":["Mouse Imaging Center - Hospital for Sick Children, Department of Medical Biophysics -University of Toronto, Toronto, Ontario, M5T 3H7, Canada","Mouse Imaging Center \u2013 Hospital for Sick Children, Department of Medical Biophysics -University of Toronto, Toronto, Ontario, M5T 3H7, Canada"],"affiliations":[{"raw_affiliation_string":"Mouse Imaging Center - Hospital for Sick Children, Department of Medical Biophysics -University of Toronto, Toronto, Ontario, M5T 3H7, Canada","institution_ids":[]},{"raw_affiliation_string":"Mouse Imaging Center \u2013 Hospital for Sick Children, Department of Medical Biophysics -University of Toronto, Toronto, Ontario, M5T 3H7, Canada","institution_ids":["https://openalex.org/I185261750","https://openalex.org/I2801317318","https://openalex.org/I4210141030"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020485486","display_name":"Guillaume Elgbeili","orcid":"https://orcid.org/0000-0003-3928-6416"},"institutions":[{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Guillaume Elgbeili","raw_affiliation_strings":["Department of Psychiatry & Integrated Program in Neuroscience, McGill University, 845 Sherbrooke St W, Montreal, QC, H3A 0G4 Canada"],"affiliations":[{"raw_affiliation_string":"Department of Psychiatry & Integrated Program in Neuroscience, McGill University, 845 Sherbrooke St W, Montreal, QC, H3A 0G4 Canada","institution_ids":["https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052649667","display_name":"Blandine Courcot","orcid":null},"institutions":[{"id":"https://openalex.org/I2799434747","display_name":"Douglas Mental Health University Institute","ror":"https://ror.org/05dk2r620","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2799434747"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Blandine Courcot","raw_affiliation_strings":["Cerebral Imaging Center, Douglas Mental Health University Institute, Verdun, Quebec, H4H 1R3, Canada"],"affiliations":[{"raw_affiliation_string":"Cerebral Imaging Center, Douglas Mental Health University Institute, Verdun, Quebec, H4H 1R3, Canada","institution_ids":["https://openalex.org/I2799434747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036446265","display_name":"Naguib Mechawar","orcid":"https://orcid.org/0000-0003-4960-756X"},"institutions":[{"id":"https://openalex.org/I2799434747","display_name":"Douglas Mental Health University Institute","ror":"https://ror.org/05dk2r620","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2799434747"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Naguib Mechawar","raw_affiliation_strings":["McGill Group for Suicide Studies, Department of Psychiatry, McGill University, Douglas Mental Health University Institute, Montreal, QC, Canada"],"affiliations":[{"raw_affiliation_string":"McGill Group for Suicide Studies, Department of Psychiatry, McGill University, Douglas Mental Health University Institute, Montreal, QC, Canada","institution_ids":["https://openalex.org/I2799434747","https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016285763","display_name":"M. Mallar Chakravarty","orcid":"https://orcid.org/0000-0002-0759-5508"},"institutions":[{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]},{"id":"https://openalex.org/I2799434747","display_name":"Douglas Mental Health University Institute","ror":"https://ror.org/05dk2r620","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2799434747"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"M. Mallar Chakravarty","raw_affiliation_strings":["Department of Psychiatry & Integrated Program in Neuroscience, McGill University, 845 Sherbrooke St W, Montreal, QC, H3A 0G4 Canada; Cerebral Imaging Center, Douglas Mental Health University Institute, Verdun, Quebec, H4H 1R3, Canada; Department of Biological and Biomedical Engineering, McGill University, 845 Sherbrooke St W, Montreal, QC, H3A 0G4, Canada","Department of Psychiatry & Integrated Program in Neuroscience, McGill University, 845 Sherbrooke St W, Montreal, QC, H3A 0G4 Canada","Cerebral Imaging Center, Douglas Mental Health University Institute, Verdun, Quebec, H4H 1R3, Canada","Department of Biological and Biomedical Engineering, McGill University, 845 Sherbrooke St W, Montreal, QC, H3A 0G4, Canada"],"affiliations":[{"raw_affiliation_string":"Department of Psychiatry & Integrated Program in Neuroscience, McGill University, 845 Sherbrooke St W, Montreal, QC, H3A 0G4 Canada; Cerebral Imaging Center, Douglas Mental Health University Institute, Verdun, Quebec, H4H 1R3, Canada; Department of Biological and Biomedical Engineering, McGill University, 845 Sherbrooke St W, Montreal, QC, H3A 0G4, Canada","institution_ids":[]},{"raw_affiliation_string":"Department of Psychiatry & Integrated Program in Neuroscience, McGill University, 845 Sherbrooke St W, Montreal, QC, H3A 0G4 Canada","institution_ids":["https://openalex.org/I5023651"]},{"raw_affiliation_string":"Cerebral Imaging Center, Douglas Mental Health University Institute, Verdun, Quebec, H4H 1R3, Canada","institution_ids":["https://openalex.org/I2799434747"]},{"raw_affiliation_string":"Department of Biological and Biomedical Engineering, McGill University, 845 Sherbrooke St W, Montreal, QC, H3A 0G4, Canada","institution_ids":["https://openalex.org/I5023651"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5006041048","display_name":"Bruno Giros","orcid":"https://orcid.org/0000-0001-5876-9822"},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"funder","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"funder","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]},{"id":"https://openalex.org/I4389425265","display_name":"Neurosciences Paris-Seine","ror":"https://ror.org/02sps6z09","country_code":null,"type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4389425265"]}],"countries":["CA","FR"],"is_corresponding":true,"raw_author_name":"Bruno Giros","raw_affiliation_strings":["Department of Psychiatry & Integrated Program in Neuroscience, McGill University, 845 Sherbrooke St W, Montreal, QC, H3A 0G4 Canada; Sorbonne University, Neuroscience Paris Seine, CNRS UMR 8246, INSERM U 1130, UPMC Univ Paris 06, UM119, 75005, Paris, France. Electronic address: bruno.giros@mcgill.ca","Sorbonne University, Neuroscience Paris Seine, CNRS UMR 8246, INSERM U 1130, UPMC Univ Paris 06, UM119, 75005, Paris, France","Department of Psychiatry & Integrated Program in Neuroscience, McGill University, 845 Sherbrooke St W, Montreal, QC, H3A 0G4 Canada"],"affiliations":[{"raw_affiliation_string":"Department of Psychiatry & Integrated Program in Neuroscience, McGill University, 845 Sherbrooke St W, Montreal, QC, H3A 0G4 Canada; Sorbonne University, Neuroscience Paris Seine, CNRS UMR 8246, INSERM U 1130, UPMC Univ Paris 06, UM119, 75005, Paris, France. Electronic address: bruno.giros@mcgill.ca","institution_ids":[]},{"raw_affiliation_string":"Sorbonne University, Neuroscience Paris Seine, CNRS UMR 8246, INSERM U 1130, UPMC Univ Paris 06, UM119, 75005, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4389425265","https://openalex.org/I39804081","https://openalex.org/I1294671590"]},{"raw_affiliation_string":"Department of Psychiatry & Integrated Program in Neuroscience, McGill University, 845 Sherbrooke St W, Montreal, QC, H3A 0G4 Canada","institution_ids":["https://openalex.org/I5023651"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":11,"corresponding_author_ids":["https://openalex.org/A5006041048"],"corresponding_institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4389425265","https://openalex.org/I5023651"],"apc_list":{"value":3450,"currency":"USD","value_usd":3450},"apc_paid":null,"fwci":2.8887,"has_fulltext":false,"cited_by_count":33,"citation_normalized_percentile":{"value":0.91292302,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":100},"biblio":{"volume":"176","issue":null,"first_page":"226","last_page":"238"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dopamine-receptor-d2","display_name":"Dopamine receptor D2","score":0.7221249341964722},{"id":"https://openalex.org/keywords/haloperidol","display_name":"Haloperidol","score":0.7133432626724243},{"id":"https://openalex.org/keywords/dopamine","display_name":"Dopamine","score":0.5990839004516602},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.5525527000427246},{"id":"https://openalex.org/keywords/antipsychotic","display_name":"Antipsychotic","score":0.5455777049064636},{"id":"https://openalex.org/keywords/receptor","display_name":"Receptor","score":0.5200750231742859},{"id":"https://openalex.org/keywords/clozapine","display_name":"Clozapine","score":0.5055339336395264},{"id":"https://openalex.org/keywords/endocrinology","display_name":"Endocrinology","score":0.5032476782798767},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.49602851271629333},{"id":"https://openalex.org/keywords/dopamine-receptor","display_name":"Dopamine receptor","score":0.4881373345851898},{"id":"https://openalex.org/keywords/schizophrenia","display_name":"Schizophrenia (object-oriented programming)","score":0.4134669899940491},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.36865562200546265},{"id":"https://openalex.org/keywords/pharmacology","display_name":"Pharmacology","score":0.35743260383605957},{"id":"https://openalex.org/keywords/psychiatry","display_name":"Psychiatry","score":0.1253424882888794}],"concepts":[{"id":"https://openalex.org/C44208683","wikidata":"https://www.wikidata.org/wiki/Q15335165","display_name":"Dopamine receptor D2","level":3,"score":0.7221249341964722},{"id":"https://openalex.org/C2780948584","wikidata":"https://www.wikidata.org/wiki/Q251347","display_name":"Haloperidol","level":3,"score":0.7133432626724243},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.5990839004516602},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5525527000427246},{"id":"https://openalex.org/C2780494398","wikidata":"https://www.wikidata.org/wiki/Q208144","display_name":"Antipsychotic","level":3,"score":0.5455777049064636},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.5200750231742859},{"id":"https://openalex.org/C2780864610","wikidata":"https://www.wikidata.org/wiki/Q221361","display_name":"Clozapine","level":3,"score":0.5055339336395264},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5032476782798767},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.49602851271629333},{"id":"https://openalex.org/C120069818","wikidata":"https://www.wikidata.org/wiki/Q415496","display_name":"Dopamine receptor","level":3,"score":0.4881373345851898},{"id":"https://openalex.org/C2776412080","wikidata":"https://www.wikidata.org/wiki/Q7431605","display_name":"Schizophrenia (object-oriented programming)","level":2,"score":0.4134669899940491},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.36865562200546265},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.35743260383605957},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.1253424882888794}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D003024","descriptor_name":"Clozapine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D003024","descriptor_name":"Clozapine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D003024","descriptor_name":"Clozapine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006220","descriptor_name":"Haloperidol","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D006220","descriptor_name":"Haloperidol","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D006220","descriptor_name":"Haloperidol","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D008137","descriptor_name":"Longitudinal Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008137","descriptor_name":"Longitudinal Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008137","descriptor_name":"Longitudinal Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014150","descriptor_name":"Antipsychotic Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D014150","descriptor_name":"Antipsychotic Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D014150","descriptor_name":"Antipsychotic Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D017448","descriptor_name":"Receptors, Dopamine D2","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017448","descriptor_name":"Receptors, Dopamine D2","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017448","descriptor_name":"Receptors, Dopamine D2","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017448","descriptor_name":"Receptors, Dopamine D2","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D017448","descriptor_name":"Receptors, Dopamine D2","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D017448","descriptor_name":"Receptors, Dopamine D2","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D065127","descriptor_name":"Dopamine D2 Receptor Antagonists","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D065127","descriptor_name":"Dopamine D2 Receptor Antagonists","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D065127","descriptor_name":"Dopamine D2 Receptor Antagonists","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.neuroimage.2018.04.054","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.neuroimage.2018.04.054","pdf_url":null,"source":{"id":"https://openalex.org/S103225281","display_name":"NeuroImage","issn_l":"1053-8119","issn":["1053-8119","1095-9572"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroImage","raw_type":"journal-article"},{"id":"pmid:29704613","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29704613","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroImage","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8399999737739563,"display_name":"Good health and well-being"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320319952","display_name":"Canada Foundation for Innovation","ror":"https://ror.org/000az4664"},{"id":"https://openalex.org/F4320320994","display_name":"Canada Research Chairs","ror":"https://ror.org/0517h6h17"},{"id":"https://openalex.org/F4320334618","display_name":"Fonds de Recherche du Qu\u00e9bec - Sant\u00e9","ror":"https://ror.org/02eqrsj93"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":107,"referenced_works":["https://openalex.org/W1546116904","https://openalex.org/W1755010820","https://openalex.org/W1827567735","https://openalex.org/W1857277871","https://openalex.org/W1876943069","https://openalex.org/W1891773028","https://openalex.org/W1963603721","https://openalex.org/W1964216558","https://openalex.org/W1964828595","https://openalex.org/W1966092598","https://openalex.org/W1968122997","https://openalex.org/W1970520385","https://openalex.org/W1970928383","https://openalex.org/W1973630599","https://openalex.org/W1973974623","https://openalex.org/W1981833273","https://openalex.org/W1982513656","https://openalex.org/W1982522522","https://openalex.org/W1987492515","https://openalex.org/W1988521406","https://openalex.org/W1991603311","https://openalex.org/W1991805788","https://openalex.org/W1993175280","https://openalex.org/W1993589574","https://openalex.org/W1995343313","https://openalex.org/W1996928463","https://openalex.org/W2000628954","https://openalex.org/W2002215070","https://openalex.org/W2002993605","https://openalex.org/W2006122360","https://openalex.org/W2006398486","https://openalex.org/W2008762508","https://openalex.org/W2010726810","https://openalex.org/W2015852090","https://openalex.org/W2016184829","https://openalex.org/W2017140635","https://openalex.org/W2018742347","https://openalex.org/W2019514154","https://openalex.org/W2022902955","https://openalex.org/W2022938806","https://openalex.org/W2026522842","https://openalex.org/W2027917639","https://openalex.org/W2029267570","https://openalex.org/W2029746418","https://openalex.org/W2038755729","https://openalex.org/W2039238247","https://openalex.org/W2040635916","https://openalex.org/W2042662378","https://openalex.org/W2043581439","https://openalex.org/W2047016005","https://openalex.org/W2051925577","https://openalex.org/W2052644075","https://openalex.org/W2054278011","https://openalex.org/W2055615422","https://openalex.org/W2055994238","https://openalex.org/W2066111421","https://openalex.org/W2068513937","https://openalex.org/W2070904590","https://openalex.org/W2071679295","https://openalex.org/W2074570091","https://openalex.org/W2085360366","https://openalex.org/W2086061811","https://openalex.org/W2089873705","https://openalex.org/W2092895227","https://openalex.org/W2093664022","https://openalex.org/W2094919766","https://openalex.org/W2095738503","https://openalex.org/W2099576957","https://openalex.org/W2102076075","https://openalex.org/W2102525000","https://openalex.org/W2107481078","https://openalex.org/W2113054165","https://openalex.org/W2115115146","https://openalex.org/W2117987967","https://openalex.org/W2123997849","https://openalex.org/W2131051578","https://openalex.org/W2132980997","https://openalex.org/W2141962222","https://openalex.org/W2144923807","https://openalex.org/W2145240519","https://openalex.org/W2145602532","https://openalex.org/W2148726987","https://openalex.org/W2150760506","https://openalex.org/W2159996636","https://openalex.org/W2161959705","https://openalex.org/W2163274894","https://openalex.org/W2220342055","https://openalex.org/W2284323937","https://openalex.org/W2478117596","https://openalex.org/W2499656625","https://openalex.org/W2554026124","https://openalex.org/W2583459617","https://openalex.org/W3209860364","https://openalex.org/W4235770099","https://openalex.org/W4285719527","https://openalex.org/W6647213481","https://openalex.org/W6648750260","https://openalex.org/W6655370498","https://openalex.org/W6657037384","https://openalex.org/W6657303344","https://openalex.org/W6660614294","https://openalex.org/W6661279688","https://openalex.org/W6664295328","https://openalex.org/W6668442234","https://openalex.org/W6675516619","https://openalex.org/W6675929710","https://openalex.org/W6724072649"],"related_works":["https://openalex.org/W2084402753","https://openalex.org/W1988346923","https://openalex.org/W3093992020","https://openalex.org/W2138231636","https://openalex.org/W4244148723","https://openalex.org/W2766579212","https://openalex.org/W2054839241","https://openalex.org/W2002943255","https://openalex.org/W2007817278","https://openalex.org/W9778820"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":3},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":2}],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2025-10-10T00:00:00"}