{"id":"https://openalex.org/W2084587642","doi":"https://doi.org/10.1016/j.neuroimage.2012.06.067","title":"Striatal dopamine D2/D3 receptor binding in pathological gambling is correlated with mood-related impulsivity","display_name":"Striatal dopamine D2/D3 receptor binding in pathological gambling is correlated with mood-related impulsivity","publication_year":2012,"publication_date":"2012-07-06","ids":{"openalex":"https://openalex.org/W2084587642","doi":"https://doi.org/10.1016/j.neuroimage.2012.06.067","mag":"2084587642","pmid":"https://pubmed.ncbi.nlm.nih.gov/22776462"},"language":"en","primary_location":{"id":"doi:10.1016/j.neuroimage.2012.06.067","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.neuroimage.2012.06.067","pdf_url":null,"source":{"id":"https://openalex.org/S103225281","display_name":"NeuroImage","issn_l":"1053-8119","issn":["1053-8119","1095-9572"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroImage","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.neuroimage.2012.06.067","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003784928","display_name":"Luke Clark","orcid":"https://orcid.org/0000-0003-1103-2422"},"institutions":[{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Luke Clark","raw_affiliation_strings":["Department of Experimental Psychology, University of Cambridge, Cambridge, UK. lc260@cam.ac.uk","[Department of Experimental Psychology, University of Cambridge, Cambridge, UK]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Psychology, University of Cambridge, Cambridge, UK. lc260@cam.ac.uk","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"[Department of Experimental Psychology, University of Cambridge, Cambridge, UK]","institution_ids":["https://openalex.org/I241749"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090018275","display_name":"Paul Stokes","orcid":"https://orcid.org/0000-0002-2274-8330"},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Paul R. Stokes","raw_affiliation_strings":["Centre for Neuropsychopharmacology, Division of Brain Sciences, Department of Medicine, Imperial College London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Neuropsychopharmacology, Division of Brain Sciences, Department of Medicine, Imperial College London, UK","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112857110","display_name":"Kit Wu","orcid":null},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Kit Wu","raw_affiliation_strings":["Centre for Neuroinflammation and Neurodegeneration, Division of Brain Sciences, Department of Medicine, Imperial College London, UK","Centre for Neuroinflammation and Neurodegeneration, Division of Brain Sciences, Department of Medicine, Imperial College, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Neuroinflammation and Neurodegeneration, Division of Brain Sciences, Department of Medicine, Imperial College London, UK","institution_ids":["https://openalex.org/I47508984"]},{"raw_affiliation_string":"Centre for Neuroinflammation and Neurodegeneration, Division of Brain Sciences, Department of Medicine, Imperial College, London, UK","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084420363","display_name":"Rosanna Michalczuk","orcid":null},"institutions":[{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Rosanna Michalczuk","raw_affiliation_strings":["Department of Experimental Psychology, University of Cambridge, Cambridge, UK","[Department of Experimental Psychology, University of Cambridge, Cambridge, UK]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Psychology, University of Cambridge, Cambridge, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"[Department of Experimental Psychology, University of Cambridge, Cambridge, UK]","institution_ids":["https://openalex.org/I241749"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054326282","display_name":"Aaf Benecke","orcid":null},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Aaf Benecke","raw_affiliation_strings":["Centre for Neuropsychopharmacology, Division of Brain Sciences, Department of Medicine, Imperial College London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Neuropsychopharmacology, Division of Brain Sciences, Department of Medicine, Imperial College London, UK","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056038750","display_name":"Ben Watson","orcid":null},"institutions":[{"id":"https://openalex.org/I36234482","display_name":"University of Bristol","ror":"https://ror.org/0524sp257","country_code":"GB","type":"education","lineage":["https://openalex.org/I36234482"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ben J. Watson","raw_affiliation_strings":["Psychopharmacology Unit, University of Bristol, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Psychopharmacology Unit, University of Bristol, UK","institution_ids":["https://openalex.org/I36234482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062882785","display_name":"Alice Egerton","orcid":"https://orcid.org/0000-0003-2939-064X"},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Alice Egerton","raw_affiliation_strings":["Department of Psychosis Studies, Institute of Psychiatry, King's College London, UK","Department of Psychosis Studies, Institute of Psychiatry, King's College, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychosis Studies, Institute of Psychiatry, King's College London, UK","institution_ids":["https://openalex.org/I183935753"]},{"raw_affiliation_string":"Department of Psychosis Studies, Institute of Psychiatry, King's College, London, UK","institution_ids":["https://openalex.org/I183935753"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031881924","display_name":"Paola Piccini","orcid":"https://orcid.org/0000-0003-4162-6141"},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Paola Piccini","raw_affiliation_strings":["Centre for Neuroinflammation and Neurodegeneration, Division of Brain Sciences, Department of Medicine, Imperial College London, UK","Centre for Neuroinflammation and Neurodegeneration, Division of Brain Sciences, Department of Medicine, Imperial College, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Neuroinflammation and Neurodegeneration, Division of Brain Sciences, Department of Medicine, Imperial College London, UK","institution_ids":["https://openalex.org/I47508984"]},{"raw_affiliation_string":"Centre for Neuroinflammation and Neurodegeneration, Division of Brain Sciences, Department of Medicine, Imperial College, London, UK","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016082897","display_name":"David Nutt","orcid":"https://orcid.org/0000-0002-1286-1401"},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"David J. Nutt","raw_affiliation_strings":["Centre for Neuropsychopharmacology, Division of Brain Sciences, Department of Medicine, Imperial College London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Neuropsychopharmacology, Division of Brain Sciences, Department of Medicine, Imperial College London, UK","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033020990","display_name":"Henrietta Bowden\u2010Jones","orcid":"https://orcid.org/0000-0002-9314-3697"},"institutions":[{"id":"https://openalex.org/I21862455","display_name":"Central and North West London NHS Foundation Trust","ror":"https://ror.org/05drfg619","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I21862455"]},{"id":"https://openalex.org/I33618826","display_name":"Centre for Mental Health","ror":"https://ror.org/04yy7zb66","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I33618826"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Henrietta Bowden-Jones","raw_affiliation_strings":["Centre for Mental Health, Division of Brain Sciences, Department of Medicine, Imperial College London, UK","National Problem Gambling Clinic, Central and North West London NHS Foundation Trust, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Mental Health, Division of Brain Sciences, Department of Medicine, Imperial College London, UK","institution_ids":["https://openalex.org/I33618826","https://openalex.org/I47508984"]},{"raw_affiliation_string":"National Problem Gambling Clinic, Central and North West London NHS Foundation Trust, UK","institution_ids":["https://openalex.org/I21862455"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5080602242","display_name":"Anne Lingford\u2010Hughes","orcid":"https://orcid.org/0000-0003-4512-3453"},"institutions":[{"id":"https://openalex.org/I21862455","display_name":"Central and North West London NHS Foundation Trust","ror":"https://ror.org/05drfg619","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I21862455"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Anne R. Lingford-Hughes","raw_affiliation_strings":["Centre for Neuropsychopharmacology, Division of Brain Sciences, Department of Medicine, Imperial College London, UK","National Problem Gambling Clinic, Central and North West London NHS Foundation Trust, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Neuropsychopharmacology, Division of Brain Sciences, Department of Medicine, Imperial College London, UK","institution_ids":["https://openalex.org/I47508984"]},{"raw_affiliation_string":"National Problem Gambling Clinic, Central and North West London NHS Foundation Trust, UK","institution_ids":["https://openalex.org/I21862455"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5003784928"],"corresponding_institution_ids":["https://openalex.org/I241749"],"apc_list":{"value":3450,"currency":"USD","value_usd":3450},"apc_paid":{"value":3450,"currency":"USD","value_usd":3450},"fwci":17.9247,"has_fulltext":false,"cited_by_count":193,"citation_normalized_percentile":{"value":0.9949385,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":100},"biblio":{"volume":"63","issue":"1","first_page":"40","last_page":"46"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11705","display_name":"Gambling Behavior and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T11705","display_name":"Gambling Behavior and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.9944000244140625,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.9868999719619751,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/raclopride","display_name":"Raclopride","score":0.9147243499755859},{"id":"https://openalex.org/keywords/impulsivity","display_name":"Impulsivity","score":0.8949087858200073},{"id":"https://openalex.org/keywords/addiction","display_name":"Addiction","score":0.7102012038230896},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.6700997352600098},{"id":"https://openalex.org/keywords/dopamine","display_name":"Dopamine","score":0.6163812279701233},{"id":"https://openalex.org/keywords/dopamine-receptor-d2","display_name":"Dopamine receptor D2","score":0.579084038734436},{"id":"https://openalex.org/keywords/dopamine-receptor-d3","display_name":"Dopamine receptor D3","score":0.5660642385482788},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.4293324053287506},{"id":"https://openalex.org/keywords/mood-disorders","display_name":"Mood disorders","score":0.42072534561157227},{"id":"https://openalex.org/keywords/mood","display_name":"Mood","score":0.4144773483276367},{"id":"https://openalex.org/keywords/psychiatry","display_name":"Psychiatry","score":0.3388362526893616},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.26930779218673706},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.2325318455696106},{"id":"https://openalex.org/keywords/anxiety","display_name":"Anxiety","score":0.13636231422424316}],"concepts":[{"id":"https://openalex.org/C2781069445","wikidata":"https://www.wikidata.org/wiki/Q7279814","display_name":"Raclopride","level":4,"score":0.9147243499755859},{"id":"https://openalex.org/C2780319597","wikidata":"https://www.wikidata.org/wiki/Q1549918","display_name":"Impulsivity","level":2,"score":0.8949087858200073},{"id":"https://openalex.org/C48856860","wikidata":"https://www.wikidata.org/wiki/Q12029","display_name":"Addiction","level":2,"score":0.7102012038230896},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.6700997352600098},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.6163812279701233},{"id":"https://openalex.org/C44208683","wikidata":"https://www.wikidata.org/wiki/Q15335165","display_name":"Dopamine receptor D2","level":3,"score":0.579084038734436},{"id":"https://openalex.org/C199596767","wikidata":"https://www.wikidata.org/wiki/Q21110872","display_name":"Dopamine receptor D3","level":4,"score":0.5660642385482788},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4293324053287506},{"id":"https://openalex.org/C2777134132","wikidata":"https://www.wikidata.org/wiki/Q188638","display_name":"Mood disorders","level":3,"score":0.42072534561157227},{"id":"https://openalex.org/C2780733359","wikidata":"https://www.wikidata.org/wiki/Q331769","display_name":"Mood","level":2,"score":0.4144773483276367},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.3388362526893616},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.26930779218673706},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2325318455696106},{"id":"https://openalex.org/C558461103","wikidata":"https://www.wikidata.org/wiki/Q154430","display_name":"Anxiety","level":2,"score":0.13636231422424316}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000339","descriptor_name":"Affect","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000339","descriptor_name":"Affect","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000339","descriptor_name":"Affect","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000339","descriptor_name":"Affect","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000339","descriptor_name":"Affect","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003342","descriptor_name":"Corpus Striatum","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D003342","descriptor_name":"Corpus Striatum","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D003342","descriptor_name":"Corpus Striatum","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D003342","descriptor_name":"Corpus Striatum","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D003342","descriptor_name":"Corpus Striatum","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D003342","descriptor_name":"Corpus Striatum","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D003342","descriptor_name":"Corpus Striatum","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D003342","descriptor_name":"Corpus Striatum","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D003342","descriptor_name":"Corpus Striatum","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D003342","descriptor_name":"Corpus Striatum","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005715","descriptor_name":"Gambling","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D005715","descriptor_name":"Gambling","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D005715","descriptor_name":"Gambling","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D005715","descriptor_name":"Gambling","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D005715","descriptor_name":"Gambling","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D005715","descriptor_name":"Gambling","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D005715","descriptor_name":"Gambling","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D005715","descriptor_name":"Gambling","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D005715","descriptor_name":"Gambling","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D005715","descriptor_name":"Gambling","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007175","descriptor_name":"Impulsive Behavior","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007175","descriptor_name":"Impulsive Behavior","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007175","descriptor_name":"Impulsive Behavior","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007175","descriptor_name":"Impulsive Behavior","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007175","descriptor_name":"Impulsive Behavior","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013223","descriptor_name":"Statistics as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013223","descriptor_name":"Statistics as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013223","descriptor_name":"Statistics as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013223","descriptor_name":"Statistics as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013223","descriptor_name":"Statistics as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017448","descriptor_name":"Receptors, Dopamine D2","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017448","descriptor_name":"Receptors, Dopamine D2","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017448","descriptor_name":"Receptors, Dopamine D2","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017448","descriptor_name":"Receptors, Dopamine D2","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017448","descriptor_name":"Receptors, Dopamine D2","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D049268","descriptor_name":"Positron-Emission Tomography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D049268","descriptor_name":"Positron-Emission Tomography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D049268","descriptor_name":"Positron-Emission Tomography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D049268","descriptor_name":"Positron-Emission Tomography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D049268","descriptor_name":"Positron-Emission Tomography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D050637","descriptor_name":"Receptors, Dopamine D3","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D050637","descriptor_name":"Receptors, Dopamine D3","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D050637","descriptor_name":"Receptors, Dopamine D3","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D050637","descriptor_name":"Receptors, Dopamine D3","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D050637","descriptor_name":"Receptors, Dopamine D3","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.neuroimage.2012.06.067","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.neuroimage.2012.06.067","pdf_url":null,"source":{"id":"https://openalex.org/S103225281","display_name":"NeuroImage","issn_l":"1053-8119","issn":["1053-8119","1095-9572"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroImage","raw_type":"journal-article"},{"id":"pmid:22776462","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22776462","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroImage","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:3438449","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3438449","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Neuroimage","raw_type":"Text"},{"id":"pmh:oai:kclpure.kcl.ac.uk:publications/e3e7ca8a-f208-4815-9e0b-25299ca4d4fe","is_oa":false,"landing_page_url":"https://kclpure.kcl.ac.uk/portal/en/publications/e3e7ca8a-f208-4815-9e0b-25299ca4d4fe","pdf_url":null,"source":{"id":"https://openalex.org/S4306400216","display_name":"Research Portal (King's College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I183935753","host_organization_name":"King's College London","host_organization_lineage":["https://openalex.org/I183935753"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Clark, L, Stokes, P R, Wu, K, Michalczuk, R, Benecke, A, Watson, B J, Egerton, A, Piccini, P, Nutt, D J, Bowden-Jones, H & Lingford-Hughes, A R 2012, 'Striatal dopamine D\u2082/D\u2083 receptor binding in pathological gambling is correlated with mood-related impulsivity', NeuroImage, vol. 63, no. 1, pp. 40-6. https://doi.org/10.1016/j.neuroimage.2012.06.067","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1016/j.neuroimage.2012.06.067","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.neuroimage.2012.06.067","pdf_url":null,"source":{"id":"https://openalex.org/S103225281","display_name":"NeuroImage","issn_l":"1053-8119","issn":["1053-8119","1095-9572"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NeuroImage","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8399999737739563}],"awards":[{"id":"https://openalex.org/G3407425671","display_name":null,"funder_award_id":"G0802725","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G5557836177","display_name":null,"funder_award_id":"J-0704","funder_id":"https://openalex.org/F4320320021","funder_display_name":"Parkinson's UK"},{"id":"https://openalex.org/G5692926251","display_name":null,"funder_award_id":"G0400575","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"}],"funders":[{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320320021","display_name":"Parkinson's UK","ror":"https://ror.org/02417p338"},{"id":"https://openalex.org/F4320320138","display_name":"British Association for Psychopharmacology","ror":"https://ror.org/01ppg1t70"},{"id":"https://openalex.org/F4320331780","display_name":"Responsible Gambling Fund","ror":null},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":66,"referenced_works":["https://openalex.org/W1778874476","https://openalex.org/W1921980981","https://openalex.org/W1973104542","https://openalex.org/W1973481178","https://openalex.org/W1976053237","https://openalex.org/W1978664286","https://openalex.org/W1983332126","https://openalex.org/W1984198260","https://openalex.org/W1986867003","https://openalex.org/W1991448902","https://openalex.org/W1991472243","https://openalex.org/W1992021533","https://openalex.org/W1992615559","https://openalex.org/W1996065499","https://openalex.org/W1999834157","https://openalex.org/W2017709022","https://openalex.org/W2020346436","https://openalex.org/W2025860484","https://openalex.org/W2039253801","https://openalex.org/W2047748095","https://openalex.org/W2055017424","https://openalex.org/W2061795745","https://openalex.org/W2063062943","https://openalex.org/W2065359811","https://openalex.org/W2080914089","https://openalex.org/W2082078342","https://openalex.org/W2088522292","https://openalex.org/W2089214546","https://openalex.org/W2090481799","https://openalex.org/W2091515105","https://openalex.org/W2094134651","https://openalex.org/W2099883816","https://openalex.org/W2103073562","https://openalex.org/W2105035735","https://openalex.org/W2107429700","https://openalex.org/W2112278807","https://openalex.org/W2120077675","https://openalex.org/W2120927079","https://openalex.org/W2121784510","https://openalex.org/W2122039482","https://openalex.org/W2125364966","https://openalex.org/W2130074222","https://openalex.org/W2132002235","https://openalex.org/W2132412870","https://openalex.org/W2133698632","https://openalex.org/W2136713424","https://openalex.org/W2139591064","https://openalex.org/W2146504547","https://openalex.org/W2149852022","https://openalex.org/W2151801030","https://openalex.org/W2159056914","https://openalex.org/W2163621687","https://openalex.org/W2164125772","https://openalex.org/W2165398609","https://openalex.org/W2166462402","https://openalex.org/W2168758633","https://openalex.org/W2245231029","https://openalex.org/W2397479638","https://openalex.org/W2741423703","https://openalex.org/W3171418018","https://openalex.org/W4240601341","https://openalex.org/W4250265709","https://openalex.org/W4298379583","https://openalex.org/W6675063796","https://openalex.org/W6679354919","https://openalex.org/W7074234824"],"related_works":["https://openalex.org/W2164993307","https://openalex.org/W4231250939","https://openalex.org/W2969587200","https://openalex.org/W2015145997","https://openalex.org/W2133285326","https://openalex.org/W2016349928","https://openalex.org/W2253670156","https://openalex.org/W2752517690","https://openalex.org/W2007361617","https://openalex.org/W1964979617"],"abstract_inverted_index":{"Pathological":[0],"gambling":[1],"(PG)":[2],"is":[3],"a":[4,30,119,127],"behavioural":[5,130],"addiction":[6],"associated":[7],"with":[8,56,60,108,150],"elevated":[9],"impulsivity":[10,78,103,153],"and":[11,27,53,63,74,132],"suspected":[12],"dopamine":[13,17,47,89,124,141],"dysregulation.":[14],"Reduced":[15],"striatal":[16,46,88,123],"D(2)/D(3)":[18,48,90],"receptor":[19,49,91,142],"availability":[20,50,143],"has":[21],"been":[22],"reported":[23],"in":[24,51,87,93,98,112,122,140,144],"drug":[25,99,133],"addiction,":[26],"may":[28,154],"constitute":[29],"premorbid":[31],"vulnerability":[32],"marker":[33],"for":[34],"addictive":[35],"disorders.":[36],"The":[37,116],"aim":[38],"of":[39,118],"the":[40,76,113],"present":[41],"study":[42],"was":[43,81,105],"to":[44,95],"assess":[45],"PG,":[52],"its":[54],"association":[55],"trait":[57],"impulsivity.":[58],"Males":[59],"PG":[61,114],"(n=9)":[62,67],"male":[64],"healthy":[65],"controls":[66],"underwent":[68],"[11C]-raclopride":[69,109],"positron":[70],"emission":[71],"tomography":[72],"imaging":[73],"completed":[75],"UPPS-P":[77],"scale.":[79],"There":[80],"no":[82],"significant":[83],"difference":[84,121],"between":[85,129],"groups":[86],"availability,":[92],"contrast":[94],"previous":[96],"reports":[97],"addiction.":[100],"However,":[101],"mood-related":[102,152],"('Urgency')":[104],"negatively":[106],"correlated":[107],"binding":[110,125],"potentials":[111],"group.":[115],"absence":[117],"group":[120],"implies":[126],"distinction":[128],"addictions":[131],"addictions.":[134],"Nevertheless,":[135],"our":[136],"data":[137],"indicate":[138],"heterogeneity":[139],"disordered":[145],"gambling,":[146],"such":[147],"that":[148],"individuals":[149],"high":[151],"show":[155],"differential":[156],"benefits":[157],"from":[158],"dopamine-based":[159],"medications.":[160]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":11},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":55},{"year":2019,"cited_by_count":13},{"year":2018,"cited_by_count":14},{"year":2017,"cited_by_count":10},{"year":2016,"cited_by_count":17},{"year":2015,"cited_by_count":21},{"year":2014,"cited_by_count":15},{"year":2013,"cited_by_count":15},{"year":2012,"cited_by_count":3}],"updated_date":"2026-08-11T07:18:39.950985","created_date":"2025-10-10T00:00:00"}