{"id":"https://openalex.org/W7148456236","doi":"https://doi.org/10.1016/j.media.2026.104069","title":"Predicting neoadjuvant therapy response in breast cancer from preoperative biopsy via spatial\u2013semantic\u2013differential learning and interpretable clinicopathological-guided fusion","display_name":"Predicting neoadjuvant therapy response in breast cancer from preoperative biopsy via spatial\u2013semantic\u2013differential learning and interpretable clinicopathological-guided fusion","publication_year":2026,"publication_date":"2026-04-02","ids":{"openalex":"https://openalex.org/W7148456236","doi":"https://doi.org/10.1016/j.media.2026.104069","pmid":"https://pubmed.ncbi.nlm.nih.gov/41934741"},"language":"en","primary_location":{"id":"doi:10.1016/j.media.2026.104069","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.media.2026.104069","pdf_url":null,"source":{"id":"https://openalex.org/S116571295","display_name":"Medical Image Analysis","issn_l":"1361-8415","issn":["1361-8415","1361-8423","1361-8431"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Image Analysis","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5132752864","display_name":"Wen-Tai Hou","orcid":null},"institutions":[{"id":"https://openalex.org/I26080491","display_name":"Kunming Medical University","ror":"https://ror.org/038c3w259","country_code":"CN","type":"education","lineage":["https://openalex.org/I26080491"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wen-Tai Hou","raw_affiliation_strings":["The Third Affiliated Hospital of Kunming Medical University & Yunnan Cancer Hospital & Peking University Cancer Hospital Yunnan, Kunming, 650118, China; Shanghai Medical College, Fudan University, Shanghai, 200032, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Third Affiliated Hospital of Kunming Medical University & Yunnan Cancer Hospital & Peking University Cancer Hospital Yunnan, Kunming, 650118, China; Shanghai Medical College, Fudan University, Shanghai, 200032, China","institution_ids":["https://openalex.org/I26080491"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5132739063","display_name":"Zi-Fei Pu","orcid":null},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zi-Fei Pu","raw_affiliation_strings":["School of Intelligent System Engineering, Sun Yat-sen University, Shenzhen, 528406, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Intelligent System Engineering, Sun Yat-sen University, Shenzhen, 528406, China","institution_ids":["https://openalex.org/I157773358"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5132797912","display_name":"Ze-Yan Xu","orcid":null},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]},{"id":"https://openalex.org/I26080491","display_name":"Kunming Medical University","ror":"https://ror.org/038c3w259","country_code":"CN","type":"education","lineage":["https://openalex.org/I26080491"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ze-Yan Xu","raw_affiliation_strings":["Department of Radiology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, China; Department of Radiology, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Peking University Cancer Hospital Yunnan, Kunming, 650118, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, China; Department of Radiology, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Peking University Cancer Hospital Yunnan, Kunming, 650118, China","institution_ids":["https://openalex.org/I200296433","https://openalex.org/I26080491"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5132772306","display_name":"An-Hao Wu","orcid":null},"institutions":[{"id":"https://openalex.org/I26080491","display_name":"Kunming Medical University","ror":"https://ror.org/038c3w259","country_code":"CN","type":"education","lineage":["https://openalex.org/I26080491"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"An-Hao Wu","raw_affiliation_strings":["The Third Affiliated Hospital of Kunming Medical University & Yunnan Cancer Hospital & Peking University Cancer Hospital Yunnan, Kunming, 650118, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Third Affiliated Hospital of Kunming Medical University & Yunnan Cancer Hospital & Peking University Cancer Hospital Yunnan, Kunming, 650118, China","institution_ids":["https://openalex.org/I26080491"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100421224","display_name":"Zhihao Liu","orcid":"https://orcid.org/0000-0003-1644-0679"},"institutions":[{"id":"https://openalex.org/I26080491","display_name":"Kunming Medical University","ror":"https://ror.org/038c3w259","country_code":"CN","type":"education","lineage":["https://openalex.org/I26080491"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhi-Hao Liu","raw_affiliation_strings":["The Third Affiliated Hospital of Kunming Medical University & Yunnan Cancer Hospital & Peking University Cancer Hospital Yunnan, Kunming, 650118, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Third Affiliated Hospital of Kunming Medical University & Yunnan Cancer Hospital & Peking University Cancer Hospital Yunnan, Kunming, 650118, China","institution_ids":["https://openalex.org/I26080491"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5132819668","display_name":"Ke Zhao","orcid":null},"institutions":[{"id":"https://openalex.org/I4210145693","display_name":"Guangdong Academy of Medical Sciences","ror":"https://ror.org/0432p8t34","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210145693"]},{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ke Zhao","raw_affiliation_strings":["Department of Radiology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, China; Provincial Key Laboratory of Artificial Intelligence in Medical Image Analysis and Application, Guangzhou, 510080, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, China; Provincial Key Laboratory of Artificial Intelligence in Medical Image Analysis and Application, Guangzhou, 510080, China","institution_ids":["https://openalex.org/I4210145693","https://openalex.org/I58200834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5132784569","display_name":"Cheng-Lu Duan","orcid":null},"institutions":[{"id":"https://openalex.org/I26080491","display_name":"Kunming Medical University","ror":"https://ror.org/038c3w259","country_code":"CN","type":"education","lineage":["https://openalex.org/I26080491"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Cheng-Lu Duan","raw_affiliation_strings":["The Third Affiliated Hospital of Kunming Medical University & Yunnan Cancer Hospital & Peking University Cancer Hospital Yunnan, Kunming, 650118, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Third Affiliated Hospital of Kunming Medical University & Yunnan Cancer Hospital & Peking University Cancer Hospital Yunnan, Kunming, 650118, China","institution_ids":["https://openalex.org/I26080491"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5132824987","display_name":"Jia Guo","orcid":null},"institutions":[{"id":"https://openalex.org/I26080491","display_name":"Kunming Medical University","ror":"https://ror.org/038c3w259","country_code":"CN","type":"education","lineage":["https://openalex.org/I26080491"]},{"id":"https://openalex.org/I4210120169","display_name":"First Affiliated Hospital of Kunming Medical University","ror":"https://ror.org/02g01ht84","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210120169"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jia Guo","raw_affiliation_strings":["Department of Radiology, First Affiliated Hospital of Kunming Medical University, Kunming, 650118, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, First Affiliated Hospital of Kunming Medical University, Kunming, 650118, China","institution_ids":["https://openalex.org/I26080491","https://openalex.org/I4210120169"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5132820843","display_name":"Kai Chen","orcid":null},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210097354","display_name":"Sun Yat-sen Memorial Hospital","ror":"https://ror.org/01px77p81","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097354"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kai Chen","raw_affiliation_strings":["Sun Yat-Sen Memorial Hospital, Guangzhou, 510120, Guangdong, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sun Yat-Sen Memorial Hospital, Guangzhou, 510120, Guangdong, China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210097354"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106667660","display_name":"Si-Qi Qiu","orcid":"https://orcid.org/0000-0002-8870-0639"},"institutions":[{"id":"https://openalex.org/I4210139852","display_name":"Shantou Central Hospital","ror":"https://ror.org/04jmrra88","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210139852"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Si-Qi Qiu","raw_affiliation_strings":["Clinical Research Center, Shantou Central Hospital, Shantou, 515041, Guangdong, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Research Center, Shantou Central Hospital, Shantou, 515041, Guangdong, China","institution_ids":["https://openalex.org/I4210139852"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023091028","display_name":"Zhicheng Du","orcid":"https://orcid.org/0000-0002-1155-8443"},"institutions":[{"id":"https://openalex.org/I191208505","display_name":"Xiamen University","ror":"https://ror.org/00mcjh785","country_code":"CN","type":"education","lineage":["https://openalex.org/I191208505"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhi-Cheng Du","raw_affiliation_strings":["Fujian Key Laboratory of Precision Diagnosis and Treatment in Breast Cancer, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, 361100, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fujian Key Laboratory of Precision Diagnosis and Treatment in Breast Cancer, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, 361100, China","institution_ids":["https://openalex.org/I191208505"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5132815764","display_name":"Xue Zhao","orcid":null},"institutions":[{"id":"https://openalex.org/I191208505","display_name":"Xiamen University","ror":"https://ror.org/00mcjh785","country_code":"CN","type":"education","lineage":["https://openalex.org/I191208505"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xue Zhao","raw_affiliation_strings":["Fujian Key Laboratory of Precision Diagnosis and Treatment in Breast Cancer, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, 361100, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fujian Key Laboratory of Precision Diagnosis and Treatment in Breast Cancer, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, 361100, China","institution_ids":["https://openalex.org/I191208505"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070941151","display_name":"Jing\u2010Wen Bai","orcid":"https://orcid.org/0000-0002-2107-2746"},"institutions":[{"id":"https://openalex.org/I26080491","display_name":"Kunming Medical University","ror":"https://ror.org/038c3w259","country_code":"CN","type":"education","lineage":["https://openalex.org/I26080491"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jing-Wen Bai","raw_affiliation_strings":["The Third Affiliated Hospital of Kunming Medical University & Yunnan Cancer Hospital & Peking University Cancer Hospital Yunnan, Kunming, 650118, China; Department of Rehabilitation and Palliative Medicine, Yunnan Cancer Hospital, Kunming, 650118, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Third Affiliated Hospital of Kunming Medical University & Yunnan Cancer Hospital & Peking University Cancer Hospital Yunnan, Kunming, 650118, China; Department of Rehabilitation and Palliative Medicine, Yunnan Cancer Hospital, Kunming, 650118, China","institution_ids":["https://openalex.org/I26080491"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5132812592","display_name":"Huan-Cheng Zeng","orcid":null},"institutions":[{"id":"https://openalex.org/I32574673","display_name":"Shantou University","ror":"https://ror.org/01a099706","country_code":"CN","type":"education","lineage":["https://openalex.org/I32574673"]},{"id":"https://openalex.org/I4210091098","display_name":"Cancer Hospital of Shantou University Medical College","ror":"https://ror.org/00a53nq42","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210091098"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Huan-Cheng Zeng","raw_affiliation_strings":["The Breast Center, Cancer Hospital of Shantou University Medical College, Shantou, 515041, China. Electronic address: hczeng1989@126.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Breast Center, Cancer Hospital of Shantou University Medical College, Shantou, 515041, China. Electronic address: hczeng1989@126.com","institution_ids":["https://openalex.org/I32574673","https://openalex.org/I4210091098"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5132814083","display_name":"Guo-Jun Zhang","orcid":null},"institutions":[{"id":"https://openalex.org/I191208505","display_name":"Xiamen University","ror":"https://ror.org/00mcjh785","country_code":"CN","type":"education","lineage":["https://openalex.org/I191208505"]},{"id":"https://openalex.org/I26080491","display_name":"Kunming Medical University","ror":"https://ror.org/038c3w259","country_code":"CN","type":"education","lineage":["https://openalex.org/I26080491"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Guo-Jun Zhang","raw_affiliation_strings":["The Third Affiliated Hospital of Kunming Medical University & Yunnan Cancer Hospital & Peking University Cancer Hospital Yunnan, Kunming, 650118, China; Fujian Key Laboratory of Precision Diagnosis and Treatment in Breast Cancer, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, 361100, China; Xiamen Key Laboratory of Endocrine-Related Cancer Precision Medicine, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, 361100, China. Electronic address: zhangguojun@kmmu.edu.cn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Third Affiliated Hospital of Kunming Medical University & Yunnan Cancer Hospital & Peking University Cancer Hospital Yunnan, Kunming, 650118, China; Fujian Key Laboratory of Precision Diagnosis and Treatment in Breast Cancer, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, 361100, China; Xiamen Key Laboratory of Endocrine-Related Cancer Precision Medicine, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, 361100, China. Electronic address: zhangguojun@kmmu.edu.cn","institution_ids":["https://openalex.org/I191208505","https://openalex.org/I26080491"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":11,"corresponding_author_ids":["https://openalex.org/A5132812592","https://openalex.org/A5132814083"],"corresponding_institution_ids":["https://openalex.org/I191208505","https://openalex.org/I26080491","https://openalex.org/I32574673","https://openalex.org/I4210091098"],"apc_list":{"value":3970,"currency":"USD","value_usd":3970},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.40771536,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"111","issue":null,"first_page":"104069","last_page":"104069"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.78329998254776,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.78329998254776,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.020999999716877937,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.01769999973475933,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/breast-cancer","display_name":"Breast cancer","score":0.7494000196456909},{"id":"https://openalex.org/keywords/neoadjuvant-therapy","display_name":"Neoadjuvant therapy","score":0.6955000162124634},{"id":"https://openalex.org/keywords/biopsy","display_name":"Biopsy","score":0.4796999990940094},{"id":"https://openalex.org/keywords/preoperative-care","display_name":"Preoperative care","score":0.3693000078201294},{"id":"https://openalex.org/keywords/breast-biopsy","display_name":"Breast biopsy","score":0.33309999108314514},{"id":"https://openalex.org/keywords/medline","display_name":"MEDLINE","score":0.30970001220703125}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8510000109672546},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.7494000196456909},{"id":"https://openalex.org/C2778292576","wikidata":"https://www.wikidata.org/wiki/Q6991934","display_name":"Neoadjuvant therapy","level":4,"score":0.6955000162124634},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.5802000164985657},{"id":"https://openalex.org/C2775934546","wikidata":"https://www.wikidata.org/wiki/Q179991","display_name":"Biopsy","level":2,"score":0.4796999990940094},{"id":"https://openalex.org/C2777722626","wikidata":"https://www.wikidata.org/wiki/Q2902695","display_name":"Preoperative care","level":2,"score":0.3693000078201294},{"id":"https://openalex.org/C2777517664","wikidata":"https://www.wikidata.org/wiki/Q4959785","display_name":"Breast biopsy","level":5,"score":0.33309999108314514},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.30970001220703125},{"id":"https://openalex.org/C3019096185","wikidata":"https://www.wikidata.org/wiki/Q1340863","display_name":"Complete response","level":3,"score":0.298799991607666},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2865999937057495},{"id":"https://openalex.org/C158525013","wikidata":"https://www.wikidata.org/wiki/Q2593739","display_name":"Fusion","level":2,"score":0.2667999863624573},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.2653000056743622},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.2572999894618988},{"id":"https://openalex.org/C198433322","wikidata":"https://www.wikidata.org/wiki/Q3910099","display_name":"Predictive value of tests","level":2,"score":0.2556999921798706},{"id":"https://openalex.org/C2777704003","wikidata":"https://www.wikidata.org/wiki/Q4959802","display_name":"Breast surgery","level":4,"score":0.25110000371932983},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.2506999969482422}],"mesh":[{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000095384","descriptor_name":"Pathologic Complete Response","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000095384","descriptor_name":"Pathologic Complete Response","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000095384","descriptor_name":"Pathologic Complete Response","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000098412","descriptor_name":"Predictive Learning Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000098412","descriptor_name":"Predictive Learning Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000098412","descriptor_name":"Predictive Learning Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001706","descriptor_name":"Biopsy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001706","descriptor_name":"Biopsy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001706","descriptor_name":"Biopsy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020360","descriptor_name":"Neoadjuvant Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020360","descriptor_name":"Neoadjuvant Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020360","descriptor_name":"Neoadjuvant Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020360","descriptor_name":"Neoadjuvant Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020360","descriptor_name":"Neoadjuvant Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.media.2026.104069","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.media.2026.104069","pdf_url":null,"source":{"id":"https://openalex.org/S116571295","display_name":"Medical Image Analysis","issn_l":"1361-8415","issn":["1361-8415","1361-8423","1361-8431"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Image Analysis","raw_type":"journal-article"},{"id":"pmid:41934741","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41934741","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical image analysis","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.45485129952430725}],"awards":[{"id":"https://openalex.org/G1342940399","display_name":null,"funder_award_id":"202501CF070031","funder_id":"https://openalex.org/F4320334984","funder_display_name":"Applied Basic Research Key Project of Yunnan"},{"id":"https://openalex.org/G1367788501","display_name":null,"funder_award_id":"32171363","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G597108651","display_name":null,"funder_award_id":"202403AC100014","funder_id":"https://openalex.org/F4320334984","funder_display_name":"Applied Basic Research Key Project of Yunnan"},{"id":"https://openalex.org/G6003505740","display_name":null,"funder_award_id":"82402228","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6143403355","display_name":null,"funder_award_id":"2025MD774091","funder_id":"https://openalex.org/F4320321543","funder_display_name":"China Postdoctoral Science Foundation"},{"id":"https://openalex.org/G7131955281","display_name":null,"funder_award_id":"62561036","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321543","display_name":"China Postdoctoral Science Foundation","ror":"https://ror.org/0426zh255"},{"id":"https://openalex.org/F4320327808","display_name":"Yunnan Key Research and Development Program","ror":null},{"id":"https://openalex.org/F4320334984","display_name":"Applied Basic Research Key Project of Yunnan","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W2161395451","https://openalex.org/W2996092187","https://openalex.org/W3006134372","https://openalex.org/W3127317646","https://openalex.org/W3135547872","https://openalex.org/W3157823694","https://openalex.org/W3195193388","https://openalex.org/W3205802794","https://openalex.org/W4213418594","https://openalex.org/W4295082389","https://openalex.org/W4313549663","https://openalex.org/W4360796946","https://openalex.org/W4361802136","https://openalex.org/W4366368294","https://openalex.org/W4380871788","https://openalex.org/W4381198685","https://openalex.org/W4385212704","https://openalex.org/W4390873054","https://openalex.org/W4392947521","https://openalex.org/W4392947532","https://openalex.org/W4394680572","https://openalex.org/W4403851812","https://openalex.org/W4406121340","https://openalex.org/W4408738796","https://openalex.org/W4416082112"],"related_works":[],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-07-22T07:51:19.307946","created_date":"2026-04-03T00:00:00"}