{"id":"https://openalex.org/W4401479535","doi":"https://doi.org/10.1016/j.media.2024.103296","title":"Metadata-enhanced contrastive learning from retinal optical coherence tomography images","display_name":"Metadata-enhanced contrastive learning from retinal optical coherence tomography images","publication_year":2024,"publication_date":"2024-08-10","ids":{"openalex":"https://openalex.org/W4401479535","doi":"https://doi.org/10.1016/j.media.2024.103296","pmid":"https://pubmed.ncbi.nlm.nih.gov/39154616"},"language":"en","primary_location":{"id":"doi:10.1016/j.media.2024.103296","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.media.2024.103296","pdf_url":null,"source":{"id":"https://openalex.org/S116571295","display_name":"Medical Image Analysis","issn_l":"1361-8415","issn":["1361-8415","1361-8423","1361-8431"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Image Analysis","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.media.2024.103296","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5081687968","display_name":"Robbie Holland","orcid":"https://orcid.org/0000-0001-8373-8390"},"institutions":[{"id":"https://openalex.org/I4210109636","display_name":"NIHR Imperial Biomedical Research Centre","ror":"https://ror.org/01kmhx639","country_code":"GB","type":"facility","lineage":["https://openalex.org/I34931013","https://openalex.org/I4210109636"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Robbie Holland","raw_affiliation_strings":["BioMedIA, Imperial College London, London, United Kingdom. Electronic address: robert.holland15@ic.ac.uk","BioMedIA, Imperial College London, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BioMedIA, Imperial College London, London, United Kingdom. Electronic address: robert.holland15@ic.ac.uk","institution_ids":["https://openalex.org/I4210109636"]},{"raw_affiliation_string":"BioMedIA, Imperial College London, London, United Kingdom","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086957236","display_name":"Oliver Leingang","orcid":"https://orcid.org/0000-0003-4569-3819"},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Oliver Leingang","raw_affiliation_strings":["Laboratory for Ophthalmic Image Analysis, Medical University of Vienna, Vienna, Austria"],"raw_orcid":"https://orcid.org/0000-0003-4569-3819","affiliations":[{"raw_affiliation_string":"Laboratory for Ophthalmic Image Analysis, Medical University of Vienna, Vienna, Austria","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089575197","display_name":"Hrvoje Bogunovi\u0107","orcid":"https://orcid.org/0000-0002-9168-0894"},"institutions":[{"id":"https://openalex.org/I4210105054","display_name":"Christian Doppler Laboratory for Thermoelectricity","ror":"https://ror.org/01cbw5x35","country_code":"AT","type":"facility","lineage":["https://openalex.org/I129774422","https://openalex.org/I145847075","https://openalex.org/I4210105054"]},{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Hrvoje Bogunovi\u0107","raw_affiliation_strings":["Laboratory for Ophthalmic Image Analysis, Medical University of Vienna, Vienna, Austria; Christian Doppler Lab for Artificial Intelligence in Retina, Medical University of Vienna, Vienna, Austria","Laboratory for Ophthalmic Image Analysis, Medical University of Vienna, Vienna, Austria","Christian Doppler Lab for Artificial Intelligence in Retina, Medical University of Vienna, Vienna, Austria"],"raw_orcid":"https://orcid.org/0000-0002-9168-0894","affiliations":[{"raw_affiliation_string":"Laboratory for Ophthalmic Image Analysis, Medical University of Vienna, Vienna, Austria; Christian Doppler Lab for Artificial Intelligence in Retina, Medical University of Vienna, Vienna, Austria","institution_ids":["https://openalex.org/I4210105054","https://openalex.org/I76134821"]},{"raw_affiliation_string":"Laboratory for Ophthalmic Image Analysis, Medical University of Vienna, Vienna, Austria","institution_ids":["https://openalex.org/I76134821"]},{"raw_affiliation_string":"Christian Doppler Lab for Artificial Intelligence in Retina, Medical University of Vienna, Vienna, Austria","institution_ids":["https://openalex.org/I4210105054","https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045507552","display_name":"Sophie Riedl","orcid":"https://orcid.org/0000-0003-0003-0886"},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Sophie Riedl","raw_affiliation_strings":["Laboratory for Ophthalmic Image Analysis, Medical University of Vienna, Vienna, Austria"],"raw_orcid":"https://orcid.org/0000-0003-0003-0886","affiliations":[{"raw_affiliation_string":"Laboratory for Ophthalmic Image Analysis, Medical University of Vienna, Vienna, Austria","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006257131","display_name":"Lars G. Fritsche","orcid":"https://orcid.org/0000-0002-2110-1690"},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lars Fritsche","raw_affiliation_strings":["Department of Biostatistics, University of Michigan, Ann Arbor, MI, United States"],"raw_orcid":"https://orcid.org/0000-0002-2110-1690","affiliations":[{"raw_affiliation_string":"Department of Biostatistics, University of Michigan, Ann Arbor, MI, United States","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076798733","display_name":"A Toby Prevost","orcid":"https://orcid.org/0000-0003-1723-0796"},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Toby Prevost","raw_affiliation_strings":["Nightingale-Saunders Clinical Trials & Epidemiology Unit, King's College London, London, United Kingdom"],"raw_orcid":"https://orcid.org/0000-0003-1723-0796","affiliations":[{"raw_affiliation_string":"Nightingale-Saunders Clinical Trials & Epidemiology Unit, King's College London, London, United Kingdom","institution_ids":["https://openalex.org/I183935753"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059328359","display_name":"Hendrik P. N. Scholl","orcid":"https://orcid.org/0000-0002-7312-0316"},"institutions":[{"id":"https://openalex.org/I1850255","display_name":"University of Basel","ror":"https://ror.org/02s6k3f65","country_code":"CH","type":"education","lineage":["https://openalex.org/I1850255"]},{"id":"https://openalex.org/I4210128905","display_name":"Department of Biomedicine Basel","ror":"https://ror.org/03ybx0x41","country_code":"CH","type":"facility","lineage":["https://openalex.org/I4210128905"]},{"id":"https://openalex.org/I4210165657","display_name":"Institute of Molecular and Clinical Ophthalmology Basel","ror":"https://ror.org/05e715194","country_code":"CH","type":"nonprofit","lineage":["https://openalex.org/I4210165657"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Hendrik P.N. Scholl","raw_affiliation_strings":["Institute of Molecular and Clinical Ophthalmology Basel, Basel, Basel-Stadt, Switzerland; Department of Ophthalmology, Universitat Basel, Basel, Basel-Stadt, Switzerland","Department of Ophthalmology, Universitat Basel, Basel, Basel-Stadt, Switzerland","Institute of Molecular and Clinical Ophthalmology Basel, Basel, Basel-Stadt, Switzerland"],"raw_orcid":"https://orcid.org/0000-0002-7312-0316","affiliations":[{"raw_affiliation_string":"Institute of Molecular and Clinical Ophthalmology Basel, Basel, Basel-Stadt, Switzerland; Department of Ophthalmology, Universitat Basel, Basel, Basel-Stadt, Switzerland","institution_ids":["https://openalex.org/I4210165657","https://openalex.org/I4210128905","https://openalex.org/I1850255"]},{"raw_affiliation_string":"Department of Ophthalmology, Universitat Basel, Basel, Basel-Stadt, Switzerland","institution_ids":["https://openalex.org/I1850255"]},{"raw_affiliation_string":"Institute of Molecular and Clinical Ophthalmology Basel, Basel, Basel-Stadt, Switzerland","institution_ids":["https://openalex.org/I4210165657"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053563726","display_name":"Ursula Schmidt\u2010Erfurth","orcid":"https://orcid.org/0000-0002-7788-7311"},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Ursula Schmidt-Erfurth","raw_affiliation_strings":["Laboratory for Ophthalmic Image Analysis, Medical University of Vienna, Vienna, Austria"],"raw_orcid":"https://orcid.org/0000-0002-7788-7311","affiliations":[{"raw_affiliation_string":"Laboratory for Ophthalmic Image Analysis, Medical University of Vienna, Vienna, Austria","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066434934","display_name":"Sobha Sivaprasad","orcid":"https://orcid.org/0000-0001-8952-0659"},"institutions":[{"id":"https://openalex.org/I1325675289","display_name":"Moorfields Eye Hospital NHS Foundation Trust","ror":"https://ror.org/03zaddr67","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1325675289"]},{"id":"https://openalex.org/I4210150574","display_name":"Moorfields Eye Hospital","ror":"https://ror.org/03tb37539","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1325675289","https://openalex.org/I4210150574"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Sobha Sivaprasad","raw_affiliation_strings":["Institute of Ophthalmology, University College London, London, United Kingdom; Moorfields National Institute for Health and Care Biomedical Research Centre, Moorfields Eye Hospital, London, United Kingdom","Institute of Ophthalmology, University College London, London, United Kingdom","Moorfields National Institute for Health and Care Biomedical Research Centre, Moorfields Eye Hospital, London, United Kingdom"],"raw_orcid":"https://orcid.org/0000-0001-8952-0659","affiliations":[{"raw_affiliation_string":"Institute of Ophthalmology, University College London, London, United Kingdom; Moorfields National Institute for Health and Care Biomedical Research Centre, Moorfields Eye Hospital, London, United Kingdom","institution_ids":["https://openalex.org/I1325675289","https://openalex.org/I45129253","https://openalex.org/I4210150574"]},{"raw_affiliation_string":"Institute of Ophthalmology, University College London, London, United Kingdom","institution_ids":["https://openalex.org/I45129253"]},{"raw_affiliation_string":"Moorfields National Institute for Health and Care Biomedical Research Centre, Moorfields Eye Hospital, London, United Kingdom","institution_ids":["https://openalex.org/I45129253","https://openalex.org/I4210150574"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072541133","display_name":"Andrew Lotery","orcid":"https://orcid.org/0000-0001-5541-4305"},"institutions":[{"id":"https://openalex.org/I43439940","display_name":"University of Southampton","ror":"https://ror.org/01ryk1543","country_code":"GB","type":"education","lineage":["https://openalex.org/I43439940"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Andrew J. Lotery","raw_affiliation_strings":["Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, Hampshire, United Kingdom"],"raw_orcid":"https://orcid.org/0000-0001-5541-4305","affiliations":[{"raw_affiliation_string":"Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, Hampshire, United Kingdom","institution_ids":["https://openalex.org/I43439940"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006461848","display_name":"Daniel Rueckert","orcid":"https://orcid.org/0000-0002-5683-5889"},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Daniel Rueckert","raw_affiliation_strings":["BioMedIA, Imperial College London, London, United Kingdom"],"raw_orcid":"https://orcid.org/0000-0002-5683-5889","affiliations":[{"raw_affiliation_string":"BioMedIA, Imperial College London, London, United Kingdom","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005001205","display_name":"Martin J. Menten","orcid":"https://orcid.org/0000-0001-8261-7810"},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]},{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE","GB"],"is_corresponding":false,"raw_author_name":"Martin J. Menten","raw_affiliation_strings":["BioMedIA, Imperial College London, London, United Kingdom; Institute for AI and Informatics in Medicine, Technical University of Munich, Munich, Bavaria, Germany","Institute for AI and Informatics in Medicine, Technical University of Munich, Munich, Bavaria, Germany","BioMedIA, Imperial College London, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BioMedIA, Imperial College London, London, United Kingdom; Institute for AI and Informatics in Medicine, Technical University of Munich, Munich, Bavaria, Germany","institution_ids":["https://openalex.org/I62916508"]},{"raw_affiliation_string":"Institute for AI and Informatics in Medicine, Technical University of Munich, Munich, Bavaria, Germany","institution_ids":["https://openalex.org/I62916508"]},{"raw_affiliation_string":"BioMedIA, Imperial College London, London, United Kingdom","institution_ids":["https://openalex.org/I47508984"]}]}],"institutions":[],"countries_distinct_count":5,"institutions_distinct_count":12,"corresponding_author_ids":["https://openalex.org/A5081687968"],"corresponding_institution_ids":["https://openalex.org/I4210109636","https://openalex.org/I47508984"],"apc_list":{"value":3970,"currency":"USD","value_usd":3970},"apc_paid":{"value":3970,"currency":"USD","value_usd":3970},"fwci":4.6812,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.95288724,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"97","issue":null,"first_page":"103296","last_page":"103296"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11438","display_name":"Retinal Imaging and Analysis","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11438","display_name":"Retinal Imaging and Analysis","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12599","display_name":"Retinal and Optic Conditions","score":0.9876000285148621,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9739999771118164,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/optical-coherence-tomography","display_name":"Optical coherence tomography","score":0.8569396734237671},{"id":"https://openalex.org/keywords/metadata","display_name":"Metadata","score":0.7061961889266968},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6891288757324219},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5137978196144104},{"id":"https://openalex.org/keywords/retinal","display_name":"Retinal","score":0.4775603413581848},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.4243481755256653},{"id":"https://openalex.org/keywords/natural-language-processing","display_name":"Natural language processing","score":0.33257240056991577},{"id":"https://openalex.org/keywords/world-wide-web","display_name":"World Wide Web","score":0.17281678318977356},{"id":"https://openalex.org/keywords/optics","display_name":"Optics","score":0.16056182980537415},{"id":"https://openalex.org/keywords/ophthalmology","display_name":"Ophthalmology","score":0.14210569858551025},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.09584903717041016},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.08106759190559387}],"concepts":[{"id":"https://openalex.org/C2778818243","wikidata":"https://www.wikidata.org/wiki/Q899552","display_name":"Optical coherence tomography","level":2,"score":0.8569396734237671},{"id":"https://openalex.org/C93518851","wikidata":"https://www.wikidata.org/wiki/Q180160","display_name":"Metadata","level":2,"score":0.7061961889266968},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6891288757324219},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5137978196144104},{"id":"https://openalex.org/C2780827179","wikidata":"https://www.wikidata.org/wiki/Q422001","display_name":"Retinal","level":2,"score":0.4775603413581848},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.4243481755256653},{"id":"https://openalex.org/C204321447","wikidata":"https://www.wikidata.org/wiki/Q30642","display_name":"Natural language processing","level":1,"score":0.33257240056991577},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.17281678318977356},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.16056182980537415},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.14210569858551025},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.09584903717041016},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.08106759190559387}],"mesh":[{"descriptor_ui":"D000071253","descriptor_name":"Metadata","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000071253","descriptor_name":"Metadata","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000071253","descriptor_name":"Metadata","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000071253","descriptor_name":"Metadata","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008268","descriptor_name":"Macular Degeneration","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008268","descriptor_name":"Macular Degeneration","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008268","descriptor_name":"Macular Degeneration","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008268","descriptor_name":"Macular Degeneration","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D012160","descriptor_name":"Retina","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D012160","descriptor_name":"Retina","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D012160","descriptor_name":"Retina","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D012160","descriptor_name":"Retina","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D041623","descriptor_name":"Tomography, Optical Coherence","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D041623","descriptor_name":"Tomography, Optical Coherence","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D041623","descriptor_name":"Tomography, Optical Coherence","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D041623","descriptor_name":"Tomography, Optical Coherence","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.media.2024.103296","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.media.2024.103296","pdf_url":null,"source":{"id":"https://openalex.org/S116571295","display_name":"Medical Image Analysis","issn_l":"1361-8415","issn":["1361-8415","1361-8423","1361-8431"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Image Analysis","raw_type":"journal-article"},{"id":"pmid:39154616","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39154616","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical image analysis","raw_type":null},{"id":"pmh:oai:mediatum.ub.tum.de:node/1752857","is_oa":false,"landing_page_url":"https://mediatum.ub.tum.de/1752857","pdf_url":null,"source":{"id":"https://openalex.org/S4377196330","display_name":"mediaTUM  (Technical University of Munich)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I62916508","host_organization_name":"Technical University of Munich","host_organization_lineage":["https://openalex.org/I62916508"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.media.2024.103296","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.media.2024.103296","pdf_url":null,"source":{"id":"https://openalex.org/S116571295","display_name":"Medical Image Analysis","issn_l":"1361-8415","issn":["1361-8415","1361-8423","1361-8431"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Image Analysis","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G2813293018","display_name":null,"funder_award_id":"210572/Z/18/Z","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"}],"funders":[{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":62,"referenced_works":["https://openalex.org/W1973545783","https://openalex.org/W2100756624","https://openalex.org/W2127318120","https://openalex.org/W2160226180","https://openalex.org/W2164774194","https://openalex.org/W2194775991","https://openalex.org/W2589074029","https://openalex.org/W2732934299","https://openalex.org/W2750760359","https://openalex.org/W2844103009","https://openalex.org/W2886281300","https://openalex.org/W2953532875","https://openalex.org/W2964744899","https://openalex.org/W3007935259","https://openalex.org/W3035060554","https://openalex.org/W3035524453","https://openalex.org/W3092762369","https://openalex.org/W3100859887","https://openalex.org/W3102174132","https://openalex.org/W3120430728","https://openalex.org/W3168822201","https://openalex.org/W3171007011","https://openalex.org/W3180604575","https://openalex.org/W3195874325","https://openalex.org/W3202623927","https://openalex.org/W3212889265","https://openalex.org/W3217084439","https://openalex.org/W4210642697","https://openalex.org/W4225904073","https://openalex.org/W4232963603","https://openalex.org/W4249142012","https://openalex.org/W4281484007","https://openalex.org/W4287113377","https://openalex.org/W4287755086","https://openalex.org/W4287812705","https://openalex.org/W4288068240","https://openalex.org/W4297808394","https://openalex.org/W4313156423","https://openalex.org/W4386697749","https://openalex.org/W4403049204","https://openalex.org/W6676297131","https://openalex.org/W6684275615","https://openalex.org/W6700872662","https://openalex.org/W6701655646","https://openalex.org/W6752125923","https://openalex.org/W6765291735","https://openalex.org/W6769544393","https://openalex.org/W6774314701","https://openalex.org/W6776700526","https://openalex.org/W6779326418","https://openalex.org/W6779977557","https://openalex.org/W6779992872","https://openalex.org/W6786147341","https://openalex.org/W6791187106","https://openalex.org/W6796547181","https://openalex.org/W6801199631","https://openalex.org/W6801207085","https://openalex.org/W6807583345","https://openalex.org/W6838557147","https://openalex.org/W6841535627","https://openalex.org/W6857071955","https://openalex.org/W7015890786"],"related_works":["https://openalex.org/W2392768766","https://openalex.org/W2058118494","https://openalex.org/W2382021449","https://openalex.org/W2095118173","https://openalex.org/W2104269053","https://openalex.org/W2106424170","https://openalex.org/W1985426483","https://openalex.org/W2501188010","https://openalex.org/W1014602304","https://openalex.org/W1033756233"],"abstract_inverted_index":{"Deep":[0],"learning":[1,18,65],"has":[2],"potential":[3,280],"to":[4,21,44,59,73,117,148,206,239,260,266,277],"automate":[5],"screening,":[6],"monitoring":[7],"and":[8,24,101,172,224,248,257,274],"grading":[9],"of":[10,40,153,191,203,211,233,262,282],"disease":[11,120,212],"in":[12,94,106,230,244,286],"medical":[13,45,75,95],"images.":[14],"Pretraining":[15],"with":[16,136,194],"contrastive":[17,42,64,134,155,222,287],"enables":[19],"models":[20],"extract":[22],"robust":[23],"generalisable":[25],"features":[26],"from":[27,69,254],"natural":[28,71],"image":[29,34,53,72,76,108,112,227],"datasets,":[30],"facilitating":[31],"label-efficient":[32],"downstream":[33,236],"analysis.":[35],"However,":[36],"the":[37,70,74,79,98,113,150,201,208,279],"direct":[38],"application":[39],"conventional":[41,83,133],"methods":[43,223],"datasets":[46,96,109,182],"introduces":[47],"two":[48,87,179],"domain-specific":[49],"issues.":[50],"Firstly,":[51],"several":[52],"transformations":[54],"which":[55],"have":[56],"been":[57],"shown":[58],"be":[60,272],"crucial":[61],"for":[62,163],"effective":[63],"do":[66],"not":[67],"translate":[68],"domain.":[77],"Secondly,":[78],"assumption":[80],"made":[81],"by":[82,131],"methods,":[84],"that":[85,110],"any":[86],"images":[88,190],"are":[89],"dissimilar,":[90],"is":[91,104],"systematically":[92],"misleading":[93],"depicting":[97],"same":[99,114],"anatomy":[100],"disease.":[102],"This":[103],"exacerbated":[105],"longitudinal":[107,181],"repeatedly":[111],"patient":[115,146,164],"cohort":[116],"monitor":[118],"their":[119],"progression":[121,213],"over":[122],"time.":[123],"In":[124,176],"this":[125,158],"paper":[126],"we":[127,160,199],"tackle":[128],"these":[129],"issues":[130],"extending":[132],"frameworks":[135],"a":[137,225,246],"novel":[138],"metadata-enhanced":[139,217],"strategy.":[140],"Our":[141,216],"approach":[142,218],"employs":[143],"widely":[144],"available":[145,284],"metadata":[147,205,285],"approximate":[149],"true":[151],"set":[152],"inter-image":[154],"relationships.":[156],"To":[157],"end":[159],"employ":[161],"records":[162],"identity,":[165],"eye":[166],"position":[167],"(i.e.":[168],"left":[169],"or":[170],"right)":[171],"time":[173],"series":[174],"information.":[175],"experiments":[177],"using":[178,204],"large":[180],"containing":[183],"170,427":[184],"retinal":[185,226],"optical":[186],"coherence":[187],"tomography":[188],"(OCT)":[189],"7912":[192],"patients":[193],"age-related":[195],"macular":[196],"degeneration":[197],"(AMD),":[198],"evaluate":[200],"utility":[202],"incorporate":[207],"temporal":[209],"dynamics":[210],"into":[214],"pretraining.":[215,288],"outperforms":[219],"both":[220,245],"standard":[221],"foundation":[228],"model":[229],"five":[231],"out":[232],"six":[234],"image-level":[235],"tasks":[237,252],"related":[238],"AMD.":[240],"We":[241],"find":[242],"benefits":[243,281],"low-data":[247],"high-data":[249],"regime":[250],"across":[251],"ranging":[253],"AMD":[255],"stage":[256],"type":[258],"classification":[259],"prediction":[261],"visual":[263],"acuity.":[264],"Due":[265],"its":[267],"modularity,":[268],"our":[269],"method":[270],"can":[271],"quickly":[273],"cost-effectively":[275],"tested":[276],"establish":[278],"including":[283]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":2}],"updated_date":"2026-05-07T13:39:58.223016","created_date":"2025-10-10T00:00:00"}
