{"id":"https://openalex.org/W7154580840","doi":"https://doi.org/10.1016/j.jocs.2026.102863","title":"MCAL-DTA: A multimodal method integrating cross-attention and local feature enhancement for drug-target affinity prediction","display_name":"MCAL-DTA: A multimodal method integrating cross-attention and local feature enhancement for drug-target affinity prediction","publication_year":2026,"publication_date":"2026-04-17","ids":{"openalex":"https://openalex.org/W7154580840","doi":"https://doi.org/10.1016/j.jocs.2026.102863"},"language":"en","primary_location":{"id":"doi:10.1016/j.jocs.2026.102863","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jocs.2026.102863","pdf_url":null,"source":{"id":"https://openalex.org/S192071280","display_name":"Journal of Computational Science","issn_l":"1877-7503","issn":["1877-7503","1877-7511"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Computational Science","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5133745306","display_name":"Sifan Pang","orcid":"https://orcid.org/0009-0009-6853-4790"},"institutions":[{"id":"https://openalex.org/I10660446","display_name":"Kunming University of Science and Technology","ror":"https://ror.org/00xyeez13","country_code":"CN","type":"education","lineage":["https://openalex.org/I10660446"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Sifan Pang","raw_affiliation_strings":["Faculty of Information Engineering and Automation, Kunming University of Science and Technology, Kunming, 650050, China"],"raw_orcid":"https://orcid.org/0009-0009-6853-4790","affiliations":[{"raw_affiliation_string":"Faculty of Information Engineering and Automation, Kunming University of Science and Technology, Kunming, 650050, China","institution_ids":["https://openalex.org/I10660446"]}]},{"author_position":"last","author":{"id":null,"display_name":"Wei Dai","orcid":"https://orcid.org/0000-0002-3093-6454"},"institutions":[{"id":"https://openalex.org/I10660446","display_name":"Kunming University of Science and Technology","ror":"https://ror.org/00xyeez13","country_code":"CN","type":"education","lineage":["https://openalex.org/I10660446"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Wei Dai","raw_affiliation_strings":["Computer Technology Application Key Lab of Yunnan Province, Kunming University of Science and Technology, Kunming, 650050, China","Faculty of Information Engineering and Automation, Kunming University of Science and Technology, Kunming, 650050, China"],"raw_orcid":"https://orcid.org/0000-0002-3093-6454","affiliations":[{"raw_affiliation_string":"Computer Technology Application Key Lab of Yunnan Province, Kunming University of Science and Technology, Kunming, 650050, China","institution_ids":["https://openalex.org/I10660446"]},{"raw_affiliation_string":"Faculty of Information Engineering and Automation, Kunming University of Science and Technology, Kunming, 650050, China","institution_ids":["https://openalex.org/I10660446"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I10660446"],"apc_list":{"value":2810,"currency":"USD","value_usd":2810},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.89951495,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"98","issue":null,"first_page":"102863","last_page":"102863"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.8349000215530396,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.8349000215530396,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.10010000318288803,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.019899999722838402,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/feature","display_name":"Feature (linguistics)","score":0.6090999841690063},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.5386000275611877},{"id":"https://openalex.org/keywords/feature-extraction","display_name":"Feature extraction","score":0.2808000147342682},{"id":"https://openalex.org/keywords/feature-selection","display_name":"Feature selection","score":0.24690000712871552}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7037000060081482},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.661300003528595},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.6090999841690063},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.5386000275611877},{"id":"https://openalex.org/C52622490","wikidata":"https://www.wikidata.org/wiki/Q1026626","display_name":"Feature extraction","level":2,"score":0.2808000147342682},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.26269999146461487},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.25029999017715454},{"id":"https://openalex.org/C148483581","wikidata":"https://www.wikidata.org/wiki/Q446488","display_name":"Feature selection","level":2,"score":0.24690000712871552},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.23880000412464142},{"id":"https://openalex.org/C83665646","wikidata":"https://www.wikidata.org/wiki/Q42139305","display_name":"Feature vector","level":2,"score":0.2371000051498413}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.jocs.2026.102863","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jocs.2026.102863","pdf_url":null,"source":{"id":"https://openalex.org/S192071280","display_name":"Journal of Computational Science","issn_l":"1877-7503","issn":["1877-7503","1877-7511"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Computational Science","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":40,"referenced_works":["https://openalex.org/W1527782499","https://openalex.org/W1986240377","https://openalex.org/W1993046136","https://openalex.org/W2030860488","https://openalex.org/W2035585923","https://openalex.org/W2067324333","https://openalex.org/W2086286404","https://openalex.org/W2109991441","https://openalex.org/W2271736303","https://openalex.org/W2605952223","https://openalex.org/W2777416523","https://openalex.org/W2785947426","https://openalex.org/W2886544065","https://openalex.org/W2997997679","https://openalex.org/W3010016408","https://openalex.org/W3032123378","https://openalex.org/W3096561213","https://openalex.org/W3146944767","https://openalex.org/W3177828909","https://openalex.org/W4205167309","https://openalex.org/W4220824576","https://openalex.org/W4224981527","https://openalex.org/W4293046261","https://openalex.org/W4307178567","https://openalex.org/W4317776906","https://openalex.org/W4327550249","https://openalex.org/W4379929801","https://openalex.org/W4386525718","https://openalex.org/W4388595306","https://openalex.org/W4388714023","https://openalex.org/W4388838206","https://openalex.org/W4391490096","https://openalex.org/W4394698513","https://openalex.org/W4394754058","https://openalex.org/W4401522182","https://openalex.org/W4403114556","https://openalex.org/W4405176158","https://openalex.org/W4406279606","https://openalex.org/W4407466332","https://openalex.org/W4411925407"],"related_works":[],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-04-25T08:17:42.794288","created_date":"2026-04-17T00:00:00"}