{"id":"https://openalex.org/W2906166739","doi":"https://doi.org/10.1016/j.jocs.2018.12.013","title":"1000\u00d7 faster than PLINK: Combined FPGA and GPU accelerators for logistic regression-based detection of epistasis","display_name":"1000\u00d7 faster than PLINK: Combined FPGA and GPU accelerators for logistic regression-based detection of epistasis","publication_year":2018,"publication_date":"2018-12-24","ids":{"openalex":"https://openalex.org/W2906166739","doi":"https://doi.org/10.1016/j.jocs.2018.12.013","mag":"2906166739"},"language":"en","primary_location":{"id":"doi:10.1016/j.jocs.2018.12.013","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jocs.2018.12.013","pdf_url":null,"source":{"id":"https://openalex.org/S192071280","display_name":"Journal of Computational Science","issn_l":"1877-7503","issn":["1877-7503","1877-7511"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Computational Science","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003785979","display_name":"Lars Wienbrandt","orcid":"https://orcid.org/0000-0001-5685-2032"},"institutions":[{"id":"https://openalex.org/I4210164599","display_name":"Clinical Research Center Kiel","ror":"https://ror.org/05sw1mq09","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210164599"]},{"id":"https://openalex.org/I32021983","display_name":"Kiel University","ror":"https://ror.org/04v76ef78","country_code":"DE","type":"education","lineage":["https://openalex.org/I32021983"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Lars Wienbrandt","raw_affiliation_strings":["Institute of Clinical Molecular Biology, Kiel University, University Medical Center Schleswig-Holstein, Campus Kiel, Rosalind-Franklin-Str. 12, 24105 Kiel, Germany"],"affiliations":[{"raw_affiliation_string":"Institute of Clinical Molecular Biology, Kiel University, University Medical Center Schleswig-Holstein, Campus Kiel, Rosalind-Franklin-Str. 12, 24105 Kiel, Germany","institution_ids":["https://openalex.org/I4210164599","https://openalex.org/I32021983"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086592721","display_name":"Jan Christian K\u00e4ssens","orcid":"https://orcid.org/0000-0001-7840-1160"},"institutions":[{"id":"https://openalex.org/I4210164599","display_name":"Clinical Research Center Kiel","ror":"https://ror.org/05sw1mq09","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210164599"]},{"id":"https://openalex.org/I32021983","display_name":"Kiel University","ror":"https://ror.org/04v76ef78","country_code":"DE","type":"education","lineage":["https://openalex.org/I32021983"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Jan Christian K\u00e4ssens","raw_affiliation_strings":["Institute of Clinical Molecular Biology, Kiel University, University Medical Center Schleswig-Holstein, Campus Kiel, Rosalind-Franklin-Str. 12, 24105 Kiel, Germany"],"affiliations":[{"raw_affiliation_string":"Institute of Clinical Molecular Biology, Kiel University, University Medical Center Schleswig-Holstein, Campus Kiel, Rosalind-Franklin-Str. 12, 24105 Kiel, Germany","institution_ids":["https://openalex.org/I4210164599","https://openalex.org/I32021983"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076942430","display_name":"Matthias H\u00fcbenthal","orcid":"https://orcid.org/0000-0002-5956-3006"},"institutions":[{"id":"https://openalex.org/I4210164599","display_name":"Clinical Research Center Kiel","ror":"https://ror.org/05sw1mq09","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210164599"]},{"id":"https://openalex.org/I32021983","display_name":"Kiel University","ror":"https://ror.org/04v76ef78","country_code":"DE","type":"education","lineage":["https://openalex.org/I32021983"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Matthias H\u00fcbenthal","raw_affiliation_strings":["Institute of Clinical Molecular Biology, Kiel University, University Medical Center Schleswig-Holstein, Campus Kiel, Rosalind-Franklin-Str. 12, 24105 Kiel, Germany"],"affiliations":[{"raw_affiliation_string":"Institute of Clinical Molecular Biology, Kiel University, University Medical Center Schleswig-Holstein, Campus Kiel, Rosalind-Franklin-Str. 12, 24105 Kiel, Germany","institution_ids":["https://openalex.org/I4210164599","https://openalex.org/I32021983"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5012331187","display_name":"David Ellinghaus","orcid":"https://orcid.org/0000-0002-4332-6110"},"institutions":[{"id":"https://openalex.org/I32021983","display_name":"Kiel University","ror":"https://ror.org/04v76ef78","country_code":"DE","type":"education","lineage":["https://openalex.org/I32021983"]},{"id":"https://openalex.org/I4210164599","display_name":"Clinical Research Center Kiel","ror":"https://ror.org/05sw1mq09","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210164599"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"David Ellinghaus","raw_affiliation_strings":["Institute of Clinical Molecular Biology, Kiel University, University Medical Center Schleswig-Holstein, Campus Kiel, Rosalind-Franklin-Str. 12, 24105 Kiel, Germany"],"affiliations":[{"raw_affiliation_string":"Institute of Clinical Molecular Biology, Kiel University, University Medical Center Schleswig-Holstein, Campus Kiel, Rosalind-Franklin-Str. 12, 24105 Kiel, Germany","institution_ids":["https://openalex.org/I4210164599","https://openalex.org/I32021983"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5003785979"],"corresponding_institution_ids":["https://openalex.org/I32021983","https://openalex.org/I4210164599"],"apc_list":{"value":2810,"currency":"USD","value_usd":2810},"apc_paid":null,"fwci":1.7921,"has_fulltext":false,"cited_by_count":25,"citation_normalized_percentile":{"value":0.86606636,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":98},"biblio":{"volume":"30","issue":null,"first_page":"183","last_page":"193"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.995199978351593,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11150","display_name":"Endoplasmic Reticulum Stress and Disease","score":0.993399977684021,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/logistic-regression","display_name":"Logistic regression","score":0.7205061316490173},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6899423003196716},{"id":"https://openalex.org/keywords/speedup","display_name":"Speedup","score":0.6421335935592651},{"id":"https://openalex.org/keywords/field-programmable-gate-array","display_name":"Field-programmable gate array","score":0.5286073088645935},{"id":"https://openalex.org/keywords/epistasis","display_name":"Epistasis","score":0.5057179927825928},{"id":"https://openalex.org/keywords/parallel-computing","display_name":"Parallel computing","score":0.41786664724349976},{"id":"https://openalex.org/keywords/regression","display_name":"Regression","score":0.4131855368614197},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.36956968903541565},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.3602912127971649},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.21052032709121704},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.14197933673858643},{"id":"https://openalex.org/keywords/embedded-system","display_name":"Embedded system","score":0.1416657567024231},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.14116045832633972},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.08925539255142212}],"concepts":[{"id":"https://openalex.org/C151956035","wikidata":"https://www.wikidata.org/wiki/Q1132755","display_name":"Logistic regression","level":2,"score":0.7205061316490173},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6899423003196716},{"id":"https://openalex.org/C68339613","wikidata":"https://www.wikidata.org/wiki/Q1549489","display_name":"Speedup","level":2,"score":0.6421335935592651},{"id":"https://openalex.org/C42935608","wikidata":"https://www.wikidata.org/wiki/Q190411","display_name":"Field-programmable gate array","level":2,"score":0.5286073088645935},{"id":"https://openalex.org/C61727976","wikidata":"https://www.wikidata.org/wiki/Q751748","display_name":"Epistasis","level":3,"score":0.5057179927825928},{"id":"https://openalex.org/C173608175","wikidata":"https://www.wikidata.org/wiki/Q232661","display_name":"Parallel computing","level":1,"score":0.41786664724349976},{"id":"https://openalex.org/C83546350","wikidata":"https://www.wikidata.org/wiki/Q1139051","display_name":"Regression","level":2,"score":0.4131855368614197},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.36956968903541565},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3602912127971649},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.21052032709121704},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.14197933673858643},{"id":"https://openalex.org/C149635348","wikidata":"https://www.wikidata.org/wiki/Q193040","display_name":"Embedded system","level":1,"score":0.1416657567024231},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.14116045832633972},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.08925539255142212},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.jocs.2018.12.013","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jocs.2018.12.013","pdf_url":null,"source":{"id":"https://openalex.org/S192071280","display_name":"Journal of Computational Science","issn_l":"1877-7503","issn":["1877-7503","1877-7511"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Computational Science","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W1822695366","https://openalex.org/W1966271560","https://openalex.org/W1990144378","https://openalex.org/W2034767937","https://openalex.org/W2037098416","https://openalex.org/W2068966425","https://openalex.org/W2078029760","https://openalex.org/W2087121965","https://openalex.org/W2093217973","https://openalex.org/W2099085143","https://openalex.org/W2105842551","https://openalex.org/W2112966225","https://openalex.org/W2117138514","https://openalex.org/W2121999551","https://openalex.org/W2137655966","https://openalex.org/W2140249224","https://openalex.org/W2145022912","https://openalex.org/W2153860431","https://openalex.org/W2156429378","https://openalex.org/W2156459362","https://openalex.org/W2161633633","https://openalex.org/W2171677905","https://openalex.org/W2533949033","https://openalex.org/W2551155106","https://openalex.org/W2557509853","https://openalex.org/W2621428960","https://openalex.org/W2805053094","https://openalex.org/W2941307081","https://openalex.org/W4297695924","https://openalex.org/W6676778485","https://openalex.org/W6677864240","https://openalex.org/W6683244028","https://openalex.org/W6728387931","https://openalex.org/W6729959043","https://openalex.org/W6751805590"],"related_works":["https://openalex.org/W2317245370","https://openalex.org/W4249323025","https://openalex.org/W198851386","https://openalex.org/W1980160788","https://openalex.org/W2030310580","https://openalex.org/W947442053","https://openalex.org/W2148915962","https://openalex.org/W2283866686","https://openalex.org/W27867058","https://openalex.org/W2948365806"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}