{"id":"https://openalex.org/W7163824837","doi":"https://doi.org/10.1016/j.ijmedinf.2026.106534","title":"Web-based family-reported outcomes to assess family functioning in multiple sclerosis: an Italian multicenter digital survey","display_name":"Web-based family-reported outcomes to assess family functioning in multiple sclerosis: an Italian multicenter digital survey","publication_year":2026,"publication_date":"2026-06-07","ids":{"openalex":"https://openalex.org/W7163824837","doi":"https://doi.org/10.1016/j.ijmedinf.2026.106534","pmid":"https://pubmed.ncbi.nlm.nih.gov/42269253"},"language":"en","primary_location":{"id":"doi:10.1016/j.ijmedinf.2026.106534","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ijmedinf.2026.106534","pdf_url":null,"source":{"id":"https://openalex.org/S53142634","display_name":"International Journal of Medical Informatics","issn_l":"1386-5056","issn":["1386-5056","1872-8243"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Medical Informatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.ijmedinf.2026.106534","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5037576257","display_name":"Luigi Lavorgna","orcid":"https://orcid.org/0000-0003-4625-4236"},"institutions":[{"id":"https://openalex.org/I197809005","display_name":"University of Campania \"Luigi Vanvitelli\"","ror":"https://ror.org/02kqnpp86","country_code":"IT","type":"education","lineage":["https://openalex.org/I197809005"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Luigi Lavorgna","raw_affiliation_strings":["Department of Advanced Medical and Surgical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy"],"raw_orcid":"https://orcid.org/0000-0001-9311-1778","affiliations":[{"raw_affiliation_string":"Department of Advanced Medical and Surgical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy","institution_ids":["https://openalex.org/I197809005"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063943085","display_name":"Giuseppina Miele","orcid":"https://orcid.org/0000-0002-1910-5908"},"institutions":[{"id":"https://openalex.org/I197809005","display_name":"University of Campania \"Luigi Vanvitelli\"","ror":"https://ror.org/02kqnpp86","country_code":"IT","type":"education","lineage":["https://openalex.org/I197809005"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Giuseppina Miele","raw_affiliation_strings":["Department of Advanced Medical and Surgical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Advanced Medical and Surgical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy","institution_ids":["https://openalex.org/I197809005"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083776277","display_name":"Marta Ponzano","orcid":"https://orcid.org/0000-0003-4091-4686"},"institutions":[{"id":"https://openalex.org/I4210114239","display_name":"Department of Health","ror":"https://ror.org/0225asj53","country_code":"TW","type":"government","lineage":["https://openalex.org/I4210114239"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Marta Ponzano","raw_affiliation_strings":["Department of Health Sciences - Section of Biostatistics University of Genoa, Italy"],"raw_orcid":"https://orcid.org/0000-0003-4091-4686","affiliations":[{"raw_affiliation_string":"Department of Health Sciences - Section of Biostatistics University of Genoa, Italy","institution_ids":["https://openalex.org/I4210114239"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074170004","display_name":"Elisabetta Maida","orcid":"https://orcid.org/0009-0003-6505-0834"},"institutions":[{"id":"https://openalex.org/I4210125210","display_name":"Santobono Children's Hospital","ror":"https://ror.org/040evg982","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210125210"]},{"id":"https://openalex.org/I4210126337","display_name":"University of Campania \"Luigi Vanvitelli\"","ror":null,"country_code":"IT","type":null,"lineage":["https://openalex.org/I4210126337"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Elisabetta Maida","raw_affiliation_strings":["Department of Advanced Medical and Surgical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy; Pediatric Neurology, Santobono-Pausilipon Childrens Hospital, Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Advanced Medical and Surgical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy; Pediatric Neurology, Santobono-Pausilipon Childrens Hospital, Naples, Italy","institution_ids":["https://openalex.org/I4210125210","https://openalex.org/I4210126337"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001834406","display_name":"Gianmarco Abbadessa","orcid":"https://orcid.org/0000-0001-8912-3055"},"institutions":[{"id":"https://openalex.org/I4210126337","display_name":"University of Campania \"Luigi Vanvitelli\"","ror":null,"country_code":"IT","type":null,"lineage":["https://openalex.org/I4210126337"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Gianmarco Abbadessa","raw_affiliation_strings":["Department of Advanced Medical and Surgical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy; Department of Brain Sciences, Imperial College London, London W120BZ, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Advanced Medical and Surgical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy; Department of Brain Sciences, Imperial College London, London W120BZ, UK","institution_ids":["https://openalex.org/I4210126337"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010547046","display_name":"Floriana Bile","orcid":null},"institutions":[{"id":"https://openalex.org/I197809005","display_name":"University of Campania \"Luigi Vanvitelli\"","ror":"https://ror.org/02kqnpp86","country_code":"IT","type":"education","lineage":["https://openalex.org/I197809005"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Floriana Bile","raw_affiliation_strings":["Department of Advanced Medical and Surgical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Advanced Medical and Surgical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy","institution_ids":["https://openalex.org/I197809005"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5138091576","display_name":"Girolama Alessandra Marfia","orcid":null},"institutions":[{"id":"https://openalex.org/I116067653","display_name":"University of Rome Tor Vergata","ror":"https://ror.org/02p77k626","country_code":"IT","type":"education","lineage":["https://openalex.org/I116067653"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Girolama Alessandra Marfia","raw_affiliation_strings":["Multiple Sclerosis Clinical and Research Unit, Department of Systems Medicine, Tor Vergata, University, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Multiple Sclerosis Clinical and Research Unit, Department of Systems Medicine, Tor Vergata, University, Rome, Italy","institution_ids":["https://openalex.org/I116067653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040947413","display_name":"Doriana Landi","orcid":"https://orcid.org/0000-0002-3309-8417"},"institutions":[{"id":"https://openalex.org/I116067653","display_name":"University of Rome Tor Vergata","ror":"https://ror.org/02p77k626","country_code":"IT","type":"education","lineage":["https://openalex.org/I116067653"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Doriana Landi","raw_affiliation_strings":["Multiple Sclerosis Clinical and Research Unit, Department of Systems Medicine, Tor Vergata, University, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Multiple Sclerosis Clinical and Research Unit, Department of Systems Medicine, Tor Vergata, University, Rome, Italy","institution_ids":["https://openalex.org/I116067653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065646761","display_name":"Francesca Proietti","orcid":null},"institutions":[{"id":"https://openalex.org/I116067653","display_name":"University of Rome Tor Vergata","ror":"https://ror.org/02p77k626","country_code":"IT","type":"education","lineage":["https://openalex.org/I116067653"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Francesca Proietti","raw_affiliation_strings":["Multiple Sclerosis Clinical and Research Unit, Department of Systems Medicine, Tor Vergata, University, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Multiple Sclerosis Clinical and Research Unit, Department of Systems Medicine, Tor Vergata, University, Rome, Italy","institution_ids":["https://openalex.org/I116067653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5138097038","display_name":"Matilde Inglese","orcid":null},"institutions":[{"id":"https://openalex.org/I4210146472","display_name":"Ospedale Policlinico San Martino","ror":"https://ror.org/04d7es448","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210146472","https://openalex.org/I4210153126","https://openalex.org/I4405264730"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Matilde Inglese","raw_affiliation_strings":["Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, Genoa, Italy; IRCCS Ospedale Policlinico San Martino, Genova, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, Genoa, Italy; IRCCS Ospedale Policlinico San Martino, Genova, Italy","institution_ids":["https://openalex.org/I4210146472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027720251","display_name":"Alice Laroni","orcid":"https://orcid.org/0000-0001-5599-9788"},"institutions":[{"id":"https://openalex.org/I4210146472","display_name":"Ospedale Policlinico San Martino","ror":"https://ror.org/04d7es448","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210146472","https://openalex.org/I4210153126","https://openalex.org/I4405264730"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Alice Laroni","raw_affiliation_strings":["Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, Genoa, Italy; IRCCS Ospedale Policlinico San Martino, Genova, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, Genoa, Italy; IRCCS Ospedale Policlinico San Martino, Genova, Italy","institution_ids":["https://openalex.org/I4210146472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042852042","display_name":"Ilaria Poir\u00e8","orcid":null},"institutions":[{"id":"https://openalex.org/I4210146472","display_name":"Ospedale Policlinico San Martino","ror":"https://ror.org/04d7es448","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210146472","https://openalex.org/I4210153126","https://openalex.org/I4405264730"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Ilaria Poir\u00e8","raw_affiliation_strings":["IRCCS Ospedale Policlinico San Martino, Genova, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IRCCS Ospedale Policlinico San Martino, Genova, Italy","institution_ids":["https://openalex.org/I4210146472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5138092021","display_name":"Giuseppe Romano","orcid":null},"institutions":[{"id":"https://openalex.org/I197809005","display_name":"University of Campania \"Luigi Vanvitelli\"","ror":"https://ror.org/02kqnpp86","country_code":"IT","type":"education","lineage":["https://openalex.org/I197809005"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Giuseppe Romano","raw_affiliation_strings":["Department of Advanced Medical and Surgical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Advanced Medical and Surgical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy","institution_ids":["https://openalex.org/I197809005"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5138098868","display_name":"Elisabetta Signoriello","orcid":null},"institutions":[{"id":"https://openalex.org/I197809005","display_name":"University of Campania \"Luigi Vanvitelli\"","ror":"https://ror.org/02kqnpp86","country_code":"IT","type":"education","lineage":["https://openalex.org/I197809005"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Elisabetta Signoriello","raw_affiliation_strings":["Department of Advanced Medical and Surgical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Advanced Medical and Surgical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy","institution_ids":["https://openalex.org/I197809005"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5138093381","display_name":"Giacomo Lus","orcid":null},"institutions":[{"id":"https://openalex.org/I197809005","display_name":"University of Campania \"Luigi Vanvitelli\"","ror":"https://ror.org/02kqnpp86","country_code":"IT","type":"education","lineage":["https://openalex.org/I197809005"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Giacomo Lus","raw_affiliation_strings":["Department of Advanced Medical and Surgical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Advanced Medical and Surgical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy","institution_ids":["https://openalex.org/I197809005"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019797632","display_name":"Eleonora Ruocco","orcid":"https://orcid.org/0000-0002-3500-0153"},"institutions":[{"id":"https://openalex.org/I197809005","display_name":"University of Campania \"Luigi Vanvitelli\"","ror":"https://ror.org/02kqnpp86","country_code":"IT","type":"education","lineage":["https://openalex.org/I197809005"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Eleonora Ruocco","raw_affiliation_strings":["Dermatology Unit, Department of Mental and Physical Health and Preventive Medicine, University of Campania \"Luigi Vanvitelli\", Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dermatology Unit, Department of Mental and Physical Health and Preventive Medicine, University of Campania \"Luigi Vanvitelli\", Naples, Italy","institution_ids":["https://openalex.org/I197809005"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5138091742","display_name":"Francesca Lauro","orcid":null},"institutions":[{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Francesca Lauro","raw_affiliation_strings":["Multiple Sclerosis Clinical Care and Research Centre, Department of Neuroscience, Reproductive Sciences and Odontostomatology, Federico II University of Naples, Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Multiple Sclerosis Clinical Care and Research Centre, Department of Neuroscience, Reproductive Sciences and Odontostomatology, Federico II University of Naples, Naples, Italy","institution_ids":["https://openalex.org/I71267560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5138094541","display_name":"Laura Rosa","orcid":null},"institutions":[{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Laura Rosa","raw_affiliation_strings":["Multiple Sclerosis Clinical Care and Research Centre, Department of Neuroscience, Reproductive Sciences and Odontostomatology, Federico II University of Naples, Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Multiple Sclerosis Clinical Care and Research Centre, Department of Neuroscience, Reproductive Sciences and Odontostomatology, Federico II University of Naples, Naples, Italy","institution_ids":["https://openalex.org/I71267560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5138077474","display_name":"Roberta Lanzillo","orcid":null},"institutions":[{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Roberta Lanzillo","raw_affiliation_strings":["Multiple Sclerosis Clinical Care and Research Centre, Department of Neuroscience, Reproductive Sciences and Odontostomatology, Federico II University of Naples, Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Multiple Sclerosis Clinical Care and Research Centre, Department of Neuroscience, Reproductive Sciences and Odontostomatology, Federico II University of Naples, Naples, Italy","institution_ids":["https://openalex.org/I71267560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040235923","display_name":"Virginia Perutelli","orcid":"https://orcid.org/0000-0003-1830-040X"},"institutions":[{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Virginia Perutelli","raw_affiliation_strings":["Department of Psychology, University of Turin, Turin, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychology, University of Turin, Turin, Italy","institution_ids":["https://openalex.org/I55143463"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5138086619","display_name":"Maria Laura Di Tella","orcid":null},"institutions":[{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Maria Laura Di Tella","raw_affiliation_strings":["Department of Psychology, University of Turin, Turin, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychology, University of Turin, Turin, Italy","institution_ids":["https://openalex.org/I55143463"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086237286","display_name":"Lidia Mislin Streito","orcid":null},"institutions":[{"id":"https://openalex.org/I4210155833","display_name":"Ospedale San Luigi Gonzaga","ror":"https://ror.org/04nzv4p86","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210155833"]},{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Lidia Mislin Streito","raw_affiliation_strings":["Department of Clinical and Biological Sciences, School of Medicine, University of Turin, Azienda Ospedaliera Universitaria San Luigi Gonzaga, Turin, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical and Biological Sciences, School of Medicine, University of Turin, Azienda Ospedaliera Universitaria San Luigi Gonzaga, Turin, Italy","institution_ids":["https://openalex.org/I4210155833","https://openalex.org/I55143463"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5138079594","display_name":"Maria Pia Sormani","orcid":null},"institutions":[{"id":"https://openalex.org/I4210114239","display_name":"Department of Health","ror":"https://ror.org/0225asj53","country_code":"TW","type":"government","lineage":["https://openalex.org/I4210114239"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Maria Pia Sormani","raw_affiliation_strings":["Department of Health Sciences - Section of Biostatistics University of Genoa, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Health Sciences - Section of Biostatistics University of Genoa, Italy","institution_ids":["https://openalex.org/I4210114239"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5138083098","display_name":"Simona Bonavita","orcid":"https://orcid.org/0000-0002-8561-9720"},"institutions":[{"id":"https://openalex.org/I4210126337","display_name":"University of Campania \"Luigi Vanvitelli\"","ror":null,"country_code":"IT","type":null,"lineage":["https://openalex.org/I4210126337"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Simona Bonavita","raw_affiliation_strings":["Department of Advanced Medical and Surgical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy. Electronic address: simona.bonavita@unicampania.it"],"raw_orcid":"https://orcid.org/0000-0002-8561-9720","affiliations":[{"raw_affiliation_string":"Department of Advanced Medical and Surgical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy. Electronic address: simona.bonavita@unicampania.it","institution_ids":["https://openalex.org/I4210126337"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015280820","display_name":"Lorys Castelli","orcid":"https://orcid.org/0000-0001-5009-2271"},"institutions":[{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Lorys Castelli","raw_affiliation_strings":["Department of Psychology, University of Turin, Turin, Italy"],"raw_orcid":"https://orcid.org/0000-0001-5009-2271","affiliations":[{"raw_affiliation_string":"Department of Psychology, University of Turin, Turin, Italy","institution_ids":["https://openalex.org/I55143463"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5138103858","display_name":"Marinella Clerico","orcid":null},"institutions":[{"id":"https://openalex.org/I4210155833","display_name":"Ospedale San Luigi Gonzaga","ror":"https://ror.org/04nzv4p86","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210155833"]},{"id":"https://openalex.org/I55143463","display_name":"University of Turin","ror":"https://ror.org/048tbm396","country_code":"IT","type":"education","lineage":["https://openalex.org/I55143463"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Marinella Clerico","raw_affiliation_strings":["Department of Clinical and Biological Sciences, School of Medicine, University of Turin, Azienda Ospedaliera Universitaria San Luigi Gonzaga, Turin, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical and Biological Sciences, School of Medicine, University of Turin, Azienda Ospedaliera Universitaria San Luigi Gonzaga, Turin, Italy","institution_ids":["https://openalex.org/I4210155833","https://openalex.org/I55143463"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5138083098"],"corresponding_institution_ids":["https://openalex.org/I4210126337"],"apc_list":{"value":3210,"currency":"USD","value_usd":3210},"apc_paid":{"value":3210,"currency":"USD","value_usd":3210},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.80081953,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"218","issue":null,"first_page":"106534","last_page":"106534"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10137","display_name":"Multiple Sclerosis Research Studies","score":0.8978000283241272,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10137","display_name":"Multiple Sclerosis Research Studies","score":0.8978000283241272,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13574","display_name":"Family Support in Illness","score":0.07129999995231628,"subfield":{"id":"https://openalex.org/subfields/3312","display_name":"Sociology and Political Science"},"field":{"id":"https://openalex.org/fields/33","display_name":"Social Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11632","display_name":"Family and Disability Support Research","score":0.0031999999191612005,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/data-collection","display_name":"Data collection","score":0.3865000009536743},{"id":"https://openalex.org/keywords/medline","display_name":"MEDLINE","score":0.3589000105857849},{"id":"https://openalex.org/keywords/digital-health","display_name":"Digital health","score":0.3328000009059906},{"id":"https://openalex.org/keywords/multicenter-study","display_name":"Multicenter study","score":0.3181000053882599},{"id":"https://openalex.org/keywords/quality-of-life","display_name":"Quality of life (healthcare)","score":0.3061000108718872}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5212000012397766},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.4514999985694885},{"id":"https://openalex.org/C133462117","wikidata":"https://www.wikidata.org/wiki/Q4929239","display_name":"Data collection","level":2,"score":0.3865000009536743},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.3589000105857849},{"id":"https://openalex.org/C2780433410","wikidata":"https://www.wikidata.org/wiki/Q5276090","display_name":"Digital health","level":3,"score":0.3328000009059906},{"id":"https://openalex.org/C2992435398","wikidata":"https://www.wikidata.org/wiki/Q6934595","display_name":"Multicenter study","level":3,"score":0.3181000053882599},{"id":"https://openalex.org/C74909509","wikidata":"https://www.wikidata.org/wiki/Q10387","display_name":"Gerontology","level":1,"score":0.3109999895095825},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.30979999899864197},{"id":"https://openalex.org/C2779951463","wikidata":"https://www.wikidata.org/wiki/Q7268788","display_name":"Quality of life (healthcare)","level":2,"score":0.3061000108718872},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.2906999886035919},{"id":"https://openalex.org/C202645933","wikidata":"https://www.wikidata.org/wiki/Q4930","display_name":"eHealth","level":3,"score":0.27869999408721924},{"id":"https://openalex.org/C190248442","wikidata":"https://www.wikidata.org/wiki/Q839486","display_name":"Qualitative research","level":2,"score":0.2694000005722046}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005190","descriptor_name":"Family","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007558","descriptor_name":"Italy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009103","descriptor_name":"Multiple Sclerosis","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":true},{"descriptor_ui":"D011795","descriptor_name":"Surveys and Questionnaires","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012944","descriptor_name":"Social Support","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.ijmedinf.2026.106534","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ijmedinf.2026.106534","pdf_url":null,"source":{"id":"https://openalex.org/S53142634","display_name":"International Journal of Medical Informatics","issn_l":"1386-5056","issn":["1386-5056","1872-8243"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Medical Informatics","raw_type":"journal-article"},{"id":"pmid:42269253","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42269253","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of medical informatics","raw_type":null}],"best_oa_location":{"id":"doi:10.1016/j.ijmedinf.2026.106534","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ijmedinf.2026.106534","pdf_url":null,"source":{"id":"https://openalex.org/S53142634","display_name":"International Journal of Medical Informatics","issn_l":"1386-5056","issn":["1386-5056","1872-8243"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Medical Informatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320307776","display_name":"Merck","ror":"https://ror.org/02891sr49"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W1970198083","https://openalex.org/W1981961026","https://openalex.org/W2001930212","https://openalex.org/W2051656627","https://openalex.org/W2138017882","https://openalex.org/W2163189184","https://openalex.org/W2167859912","https://openalex.org/W2168032908","https://openalex.org/W2760560251","https://openalex.org/W2765282886","https://openalex.org/W2790432448","https://openalex.org/W2810227481","https://openalex.org/W2896014118","https://openalex.org/W2896766300","https://openalex.org/W2935851212","https://openalex.org/W2966064554","https://openalex.org/W2968188631","https://openalex.org/W2977327416","https://openalex.org/W3022677609","https://openalex.org/W3157617937","https://openalex.org/W4210439934","https://openalex.org/W4306147524","https://openalex.org/W4384664378","https://openalex.org/W4393199010","https://openalex.org/W4401388415","https://openalex.org/W4401958236","https://openalex.org/W4409192127"],"related_works":[],"abstract_inverted_index":{"BACKGROUND":[0],"AND":[1],"OBJECTIVES:":[2],"Multiple":[3],"sclerosis":[4],"(MS)":[5],"affects":[6],"not":[7],"only":[8],"individuals":[9,71],"but":[10],"also":[11],"family":[12,36,268,284],"dynamics.":[13],"Scalable,":[14],"digitally":[15,296],"delivered":[16],"assessments":[17],"may":[18,304],"support":[19,206],"routine":[20],"screening":[21,298],"of":[22,114,129,140,295],"psychosocial":[23,53,288],"and":[24,52,78,104,127,131,203,239,266,286],"relational":[25,310],"needs":[26],"across":[27],"the":[28,293],"household.":[29],"This":[30,56],"study":[31,60],"aimed":[32],"to":[33,223,300],"investigate":[34],"perceived":[35,205],"functioning":[37,269,285],"in":[38,290],"families":[39,62,302],"living":[40],"with":[41,63,67,72,178,255],"MS,":[42,291],"using":[43],"a":[44,64,90],"web-based,":[45,278],"multi-informant":[46,280],"approach,":[47],"focusing":[48],"on":[49],"relationship":[50],"quality":[51],"factors.":[54],"METHODS:":[55],"Italian":[57],"multicenter,":[58],"cross-sectional":[59],"recruited":[61],"member":[65],"diagnosed":[66],"MS.":[68],"Participants":[69,93],"included":[70,88],"MS":[73],"(PwMS),":[74],"partners,":[75],"adolescent":[76,160],"children,":[77],"other":[79],"adult":[80,169],"relatives.":[81],"Families":[82],"without":[83],"self-reported":[84],"chronic":[85],"illness":[86],"were":[87],"as":[89],"comparison":[91],"group.":[92],"completed":[94],"anonymous,":[95],"validated":[96],"online":[97],"questionnaires.":[98],"Standardized":[99],"instruments":[100],"included:":[101],"Hospital":[102],"Anxiety":[103],"Depression":[105],"Scale":[106,113,121,125],"(HADS),":[107],"Family":[108],"Assessment":[109],"Measure-III":[110],"(FAM-III),":[111],"Multidimensional":[112],"Perceived":[115],"Social":[116],"Support":[117],"(MSPSS),":[118],"Toronto":[119],"Alexithymia":[120],"(TAS-20),":[122],"Dyadic":[123],"Adjustment":[124],"(DAS),":[126],"Inventory":[128],"Parent":[130],"Peer":[132],"Attachment":[133],"(IPPA).":[134],"RESULTS:":[135],"The":[136],"final":[137],"sample":[138],"consisted":[139],"50":[141,143],"families:":[142],"PwMS":[144,180],"(mean":[145,153,162,171],"age:":[146,154,163,172],"42.6":[147],"\u00b1":[148,156,165,174],"11.4":[149],"years),":[150,158,167],"34":[151],"partners":[152],"45.2":[155],"10.6":[157],"25":[159,168],"children":[161,219],"16.2":[164],"3.6":[166],"relatives":[170],"47.2":[173],"17.7":[175],"years).":[176],"Compared":[177],"controls,":[179],"reported":[181],"lower":[182],"anxiety":[183],"(median":[184,195,210],"HADS-A:":[185],"6.5":[186],"vs.":[187,198,213,229,233,245],"9;":[188],"p":[189,200,215,236,247,263,273],"=":[190,201,216,248,261,271,274],"0.002),":[191],"higher":[192,252],"dyadic":[193],"adjustment":[194],"DAS:":[196],"109.5":[197],"104.5;":[199],"0.024)":[202],"greater":[204],"from":[207,306],"significant":[208],"others":[209],"MSPSS:":[211],"27":[212],"24;":[214],"0.047).":[217],"Adolescent":[218],"showed":[220],"stronger":[221],"attachment":[222],"parents":[224],"(IPPA":[225,241],"total":[226,242],"mother:":[227],"94":[228],"83;":[230],"father:":[231],"92.5":[232],"76.5;":[234],"both":[235],"<":[237,264],"0.001)":[238,265],"peers":[240],"peers:":[243],"98":[244],"90;":[246],"0.016).":[249],"In":[250],"PwMS,":[251],"disability":[253],"correlated":[254],"more":[256],"severe":[257],"depressive":[258],"symptoms":[259],"(\u03c1":[260,270],"0.55,":[262],"poorer":[267],"0.37,":[272],"0.009).":[275],"DISCUSSION:":[276],"A":[277],"standardized,":[279],"assessment":[281],"can":[282],"capture":[283],"key":[287],"correlates":[289],"supporting":[292],"design":[294],"enabled":[297],"pathways":[299],"identify":[301],"who":[303],"benefit":[305],"early":[307],"psychological":[308],"or":[309],"interventions.":[311]},"counts_by_year":[],"updated_date":"2026-06-29T08:53:18.405633","created_date":"2026-06-08T00:00:00"}