{"id":"https://openalex.org/W7134116780","doi":"https://doi.org/10.1016/j.ijmedinf.2026.106381","title":"Development of a complex digital lifestyle intervention for individuals with prediabetes \u2013 Using the Medical research Council (MRC) framework","display_name":"Development of a complex digital lifestyle intervention for individuals with prediabetes \u2013 Using the Medical research Council (MRC) framework","publication_year":2026,"publication_date":"2026-03-07","ids":{"openalex":"https://openalex.org/W7134116780","doi":"https://doi.org/10.1016/j.ijmedinf.2026.106381","pmid":"https://pubmed.ncbi.nlm.nih.gov/41812461"},"language":"en","primary_location":{"id":"doi:10.1016/j.ijmedinf.2026.106381","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ijmedinf.2026.106381","pdf_url":null,"source":{"id":"https://openalex.org/S53142634","display_name":"International Journal of Medical Informatics","issn_l":"1386-5056","issn":["1386-5056","1872-8243"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Medical Informatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.ijmedinf.2026.106381","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061255229","display_name":"Tanja Fredensborg Holm","orcid":"https://orcid.org/0009-0007-1725-5922"},"institutions":[{"id":"https://openalex.org/I2799976261","display_name":"Aalborg University Hospital","ror":"https://ror.org/02jk5qe80","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2799976261"]},{"id":"https://openalex.org/I891191580","display_name":"Aalborg University","ror":"https://ror.org/04m5j1k67","country_code":"DK","type":"education","lineage":["https://openalex.org/I891191580"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Tanja Fredensborg Holm","raw_affiliation_strings":["Department of Health Science and Technology, Aalborg University, Gistrup, Denmark; Steno Diabetes Center North Denmark, Aalborg University Hospital, Aalborg, Denmark"],"raw_orcid":"https://orcid.org/0009-0007-1725-5922","affiliations":[{"raw_affiliation_string":"Department of Health Science and Technology, Aalborg University, Gistrup, Denmark; Steno Diabetes Center North Denmark, Aalborg University Hospital, Aalborg, Denmark","institution_ids":["https://openalex.org/I891191580","https://openalex.org/I2799976261"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5128294396","display_name":"Pernille Fr\u00f8strup Barington","orcid":null},"institutions":[{"id":"https://openalex.org/I1339947260","display_name":"Steno Diabetes Centers","ror":"https://ror.org/03w7awk87","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I1339947260","https://openalex.org/I2802567020","https://openalex.org/I4210145385"]},{"id":"https://openalex.org/I2799976261","display_name":"Aalborg University Hospital","ror":"https://ror.org/02jk5qe80","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2799976261"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Pernille Fr\u00f8strup Barington","raw_affiliation_strings":["Steno Diabetes Center North Denmark, Aalborg University Hospital, Aalborg, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Steno Diabetes Center North Denmark, Aalborg University Hospital, Aalborg, Denmark","institution_ids":["https://openalex.org/I1339947260","https://openalex.org/I2799976261"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026810888","display_name":"Thomas Kronborg","orcid":"https://orcid.org/0000-0002-2693-0527"},"institutions":[{"id":"https://openalex.org/I2799976261","display_name":"Aalborg University Hospital","ror":"https://ror.org/02jk5qe80","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2799976261"]},{"id":"https://openalex.org/I891191580","display_name":"Aalborg University","ror":"https://ror.org/04m5j1k67","country_code":"DK","type":"education","lineage":["https://openalex.org/I891191580"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Thomas Kronborg","raw_affiliation_strings":["Department of Health Science and Technology, Aalborg University, Gistrup, Denmark; Steno Diabetes Center North Denmark, Aalborg University Hospital, Aalborg, Denmark"],"raw_orcid":"https://orcid.org/0000-0002-2693-0527","affiliations":[{"raw_affiliation_string":"Department of Health Science and Technology, Aalborg University, Gistrup, Denmark; Steno Diabetes Center North Denmark, Aalborg University Hospital, Aalborg, Denmark","institution_ids":["https://openalex.org/I891191580","https://openalex.org/I2799976261"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5128306254","display_name":"Morten Hasselstr\u00f8m Jensen","orcid":null},"institutions":[{"id":"https://openalex.org/I189090001","display_name":"Novo Nordisk (Denmark)","ror":"https://ror.org/0435rc536","country_code":"DK","type":"company","lineage":["https://openalex.org/I189090001","https://openalex.org/I2801134892","https://openalex.org/I4210159963"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Morten Hasselstr\u00f8m Jensen","raw_affiliation_strings":["Department of Health Science and Technology, Aalborg University, Gistrup, Denmark; Data Science, Novo Nordisk A/S, S\u00f8borg, Denmark"],"raw_orcid":"https://orcid.org/0000-0002-6649-8644","affiliations":[{"raw_affiliation_string":"Department of Health Science and Technology, Aalborg University, Gistrup, Denmark; Data Science, Novo Nordisk A/S, S\u00f8borg, Denmark","institution_ids":["https://openalex.org/I189090001"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5122141476","display_name":"Stine Hangaard","orcid":null},"institutions":[{"id":"https://openalex.org/I2799976261","display_name":"Aalborg University Hospital","ror":"https://ror.org/02jk5qe80","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2799976261"]},{"id":"https://openalex.org/I891191580","display_name":"Aalborg University","ror":"https://ror.org/04m5j1k67","country_code":"DK","type":"education","lineage":["https://openalex.org/I891191580"]}],"countries":["DK"],"is_corresponding":true,"raw_author_name":"Stine Hangaard","raw_affiliation_strings":["Department of Health Science and Technology, Aalborg University, Gistrup, Denmark; Steno Diabetes Center North Denmark, Aalborg University Hospital, Aalborg, Denmark. Electronic address: svh@hst.aau.dk"],"raw_orcid":"https://orcid.org/0000-0003-0395-3563","affiliations":[{"raw_affiliation_string":"Department of Health Science and Technology, Aalborg University, Gistrup, Denmark; Steno Diabetes Center North Denmark, Aalborg University Hospital, Aalborg, Denmark. Electronic address: svh@hst.aau.dk","institution_ids":["https://openalex.org/I891191580","https://openalex.org/I2799976261"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5122141476"],"corresponding_institution_ids":["https://openalex.org/I2799976261","https://openalex.org/I891191580"],"apc_list":{"value":3210,"currency":"USD","value_usd":3210},"apc_paid":{"value":3210,"currency":"USD","value_usd":3210},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.2984951,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"213","issue":null,"first_page":"106381","last_page":"106381"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11446","display_name":"Mobile Health and mHealth Applications","score":0.3328999876976013,"subfield":{"id":"https://openalex.org/subfields/3600","display_name":"General Health Professions"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11446","display_name":"Mobile Health and mHealth Applications","score":0.3328999876976013,"subfield":{"id":"https://openalex.org/subfields/3600","display_name":"General Health Professions"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10793","display_name":"Diabetes Management and Education","score":0.09350000321865082,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12745","display_name":"Dietary Effects on Health","score":0.055799998342990875,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prediabetes","display_name":"Prediabetes","score":0.8790000081062317},{"id":"https://openalex.org/keywords/intervention","display_name":"Intervention (counseling)","score":0.5708000063896179},{"id":"https://openalex.org/keywords/digital-health","display_name":"Digital health","score":0.5695000290870667},{"id":"https://openalex.org/keywords/medical-research","display_name":"Medical research","score":0.5126000046730042},{"id":"https://openalex.org/keywords/lifestyle-medicine","display_name":"Lifestyle medicine","score":0.35440000891685486},{"id":"https://openalex.org/keywords/ehealth","display_name":"eHealth","score":0.3285999894142151},{"id":"https://openalex.org/keywords/medline","display_name":"MEDLINE","score":0.3208000063896179}],"concepts":[{"id":"https://openalex.org/C2779668308","wikidata":"https://www.wikidata.org/wiki/Q2087205","display_name":"Prediabetes","level":4,"score":0.8790000081062317},{"id":"https://openalex.org/C2780665704","wikidata":"https://www.wikidata.org/wiki/Q959298","display_name":"Intervention (counseling)","level":2,"score":0.5708000063896179},{"id":"https://openalex.org/C2780433410","wikidata":"https://www.wikidata.org/wiki/Q5276090","display_name":"Digital health","level":3,"score":0.5695000290870667},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5619999766349792},{"id":"https://openalex.org/C106977388","wikidata":"https://www.wikidata.org/wiki/Q2752427","display_name":"Medical research","level":2,"score":0.5126000046730042},{"id":"https://openalex.org/C74909509","wikidata":"https://www.wikidata.org/wiki/Q10387","display_name":"Gerontology","level":1,"score":0.46880000829696655},{"id":"https://openalex.org/C509550671","wikidata":"https://www.wikidata.org/wiki/Q126945","display_name":"Medical education","level":1,"score":0.43959999084472656},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.40470001101493835},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.39410001039505005},{"id":"https://openalex.org/C2779537295","wikidata":"https://www.wikidata.org/wiki/Q1811041","display_name":"Lifestyle medicine","level":2,"score":0.35440000891685486},{"id":"https://openalex.org/C202645933","wikidata":"https://www.wikidata.org/wiki/Q4930","display_name":"eHealth","level":3,"score":0.3285999894142151},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.3208000063896179},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.3086000084877014},{"id":"https://openalex.org/C3020255362","wikidata":"https://www.wikidata.org/wiki/Q747883","display_name":"Physical activity","level":2,"score":0.30790001153945923},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.2865000069141388},{"id":"https://openalex.org/C2779318504","wikidata":"https://www.wikidata.org/wiki/Q1438035","display_name":"Research design","level":2,"score":0.27549999952316284},{"id":"https://openalex.org/C2779363104","wikidata":"https://www.wikidata.org/wiki/Q17069079","display_name":"mHealth","level":3,"score":0.27230000495910645},{"id":"https://openalex.org/C27415008","wikidata":"https://www.wikidata.org/wiki/Q7256382","display_name":"Psychological intervention","level":2,"score":0.27070000767707825},{"id":"https://openalex.org/C2780877353","wikidata":"https://www.wikidata.org/wiki/Q2518253","display_name":"Health services research","level":3,"score":0.25699999928474426},{"id":"https://openalex.org/C145642194","wikidata":"https://www.wikidata.org/wiki/Q870895","display_name":"Health informatics","level":3,"score":0.25519999861717224},{"id":"https://openalex.org/C190248442","wikidata":"https://www.wikidata.org/wiki/Q839486","display_name":"Qualitative research","level":2,"score":0.250900000333786}],"mesh":[{"descriptor_ui":"D000082222","descriptor_name":"Digital Technology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D000086825","descriptor_name":"User-Centered Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001521","descriptor_name":"Behavior Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008019","descriptor_name":"Life Style","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011236","descriptor_name":"Prediabetic State","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D040242","descriptor_name":"Risk Reduction Behavior","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.ijmedinf.2026.106381","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ijmedinf.2026.106381","pdf_url":null,"source":{"id":"https://openalex.org/S53142634","display_name":"International Journal of Medical Informatics","issn_l":"1386-5056","issn":["1386-5056","1872-8243"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Medical Informatics","raw_type":"journal-article"},{"id":"pmid:41812461","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41812461","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of medical informatics","raw_type":null},{"id":"pmh:oai:pure.atira.dk:publications/eefb6ef9-360f-424d-91e5-f2b64899bbb0","is_oa":false,"landing_page_url":"https://vbn.aau.dk/da/publications/eefb6ef9-360f-424d-91e5-f2b64899bbb0","pdf_url":null,"source":{"id":"https://openalex.org/S4306401731","display_name":"VBN Forskningsportal (Aalborg Universitet)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I891191580","host_organization_name":"Aalborg University","host_organization_lineage":["https://openalex.org/I891191580"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Holm, T F, Barington, P F, Kronborg, T, Jensen, M H & Hangaard, S 2026, 'Development of a complex digital lifestyle intervention for individuals with prediabetes \u2013 Using the Medical research Council (MRC) framework', International Journal of Medical Informatics, vol. 213, 106381. https://doi.org/10.1016/j.ijmedinf.2026.106381","raw_type":"info:eu-repo/semantics/publishedVersion"}],"best_oa_location":{"id":"doi:10.1016/j.ijmedinf.2026.106381","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ijmedinf.2026.106381","pdf_url":null,"source":{"id":"https://openalex.org/S53142634","display_name":"International Journal of Medical Informatics","issn_l":"1386-5056","issn":["1386-5056","1872-8243"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Medical Informatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":23,"referenced_works":["https://openalex.org/W1882671252","https://openalex.org/W2006625394","https://openalex.org/W2077109464","https://openalex.org/W2110720428","https://openalex.org/W2116567300","https://openalex.org/W2141211931","https://openalex.org/W2146536851","https://openalex.org/W2158822657","https://openalex.org/W2159418632","https://openalex.org/W2169434152","https://openalex.org/W2332951586","https://openalex.org/W2586413427","https://openalex.org/W2600576884","https://openalex.org/W2610117647","https://openalex.org/W2757146144","https://openalex.org/W2771761888","https://openalex.org/W2945745351","https://openalex.org/W3116592557","https://openalex.org/W4220926348","https://openalex.org/W4282916215","https://openalex.org/W4284704782","https://openalex.org/W4405127822","https://openalex.org/W4407268675"],"related_works":[],"abstract_inverted_index":{"BACKGROUND:":[0],"Prediabetes":[1],"raises":[2],"the":[3,26,90,111,118,122,125,147,153,175,181,245,274,281,307],"risk":[4,27],"of":[5,28,65,93,121,164,174,240,280,311],"developing":[6],"type":[7,328],"2":[8,329],"diabetes":[9],"(T2D)":[10],"and":[11,44,63,73,140,152,167,172,184,204,222,264,270,288,293,309],"related":[12],"complications,":[13],"making":[14],"management":[15],"vital":[16],"to":[17,48,59,83,161,179],"lessen":[18],"diabetes-related":[19],"burdens.":[20],"Intensive":[21],"lifestyle":[22,97,255],"interventions":[23,41,77,176],"can":[24],"reduce":[25],"T2D,":[29,327],"but":[30],"their":[31],"high":[32],"resource":[33],"demands":[34],"limit":[35],"widespread":[36],"use.":[37],"In":[38],"prediabetes,":[39,260],"digital":[40,96,254],"are":[42,69,78,272],"effective":[43,290],"may":[45],"improve":[46],"accessibility":[47],"preventive":[49],"healthcare":[50],"by":[51],"reducing":[52],"costs.":[53],"However,":[54],"findings":[55],"vary,":[56],"likely":[57],"due":[58,82],"insufficient":[60],"systematic":[61,278],"development":[62,91,112,129,269,282],"reporting":[64],"complex":[66,95,253],"interventions,":[67],"which":[68],"crucial":[70],"for":[71,99,257,305],"effectiveness":[72],"replication.":[74],"Many":[75],"health":[76],"considered":[79],"complex,":[80],"e.g.,":[81],"multiple":[84],"interacting":[85],"components.":[86],"This":[87,114,249],"study":[88,250,275],"reports":[89,116],"process":[92],"a":[94,193,196,201,205,252,277],"intervention":[98,126,168,189,199,210,231,256],"individuals":[100,258],"with":[101,227,259],"prediabetes.":[102],"METHODS:":[103],"The":[104,128,170,187,208,230],"Medical":[105,317],"Research":[106,318],"Council":[107],"(MRC)":[108],"framework":[109],"guided":[110],"process.":[113],"paper":[115],"on":[117],"first":[119],"phase":[120],"MRC":[123],"framework;":[124],"development.":[127],"was":[130,159],"divided":[131],"into":[132],"four":[133,212],"phases,":[134],"integrating":[135,261],"evidence":[136],"from":[137,244],"current":[138],"literature":[139],"stakeholder":[141,265],"engagement.":[142,266],"A":[143],"theoretical":[144],"framework,":[145],"combining":[146],"Theoretical":[148,324],"Domains":[149],"Framework":[150],"(TDF)":[151],"Behavior":[154,300],"Change":[155,301],"Technique":[156],"(BCT)":[157],"taxonomy,":[158],"applied":[160],"determine":[162],"mechanisms":[163,183,239],"behavior":[165,241],"change":[166,242],"content.":[169,185],"structure":[171],"components":[173],"were":[177],"developed":[178,188,251],"incorporate":[180],"identified":[182,243],"RESULTS:":[186],"is":[190],"structured":[191],"around":[192],"starting":[194],"period,":[195,200,203],"12-week":[197],"active":[198,209],"closing":[202],"follow-up":[206],"period.":[207],"comprises":[211],"main":[213],"components:":[214],"1)":[215],"Individual":[216],"contact,":[217],"2)":[218],"Education,":[219],"3)":[220],"Exercise,":[221],"4)":[223],"Social":[224],"community,":[225],"each":[226],"several":[228],"subcomponents.":[229],"integrates":[232],"29":[233],"unique":[234,238],"BCTs":[235],"targeting":[236],"12":[237],"TDF":[246],"framework.":[247],"CONCLUSION:":[248],"evidence,":[262],"theory,":[263],"While":[267],"further":[268],"testing":[271],"needed,":[273],"provides":[276],"description":[279],"process,":[283],"addressing":[284],"gaps":[285],"in":[286,295,314],"transparency":[287],"supporting":[289],"outcomes,":[291],"replication,":[292],"implementation":[294],"clinical":[296],"practice.":[297],"ABBREVIATIONS:":[298],"BCT,":[299],"Techniques;":[302],"CReDECI,":[303],"Criteria":[304],"Reporting":[306],"Development":[308],"Evaluation":[310],"Complex":[312],"Interventions":[313],"Healthcare;":[315],"MRC,":[316],"Council;":[319],"PROs,":[320],"Patient-related":[321],"outcomes;":[322],"TDF,":[323],"Domain":[325],"Framework;":[326],"diabetes.":[330]},"counts_by_year":[],"updated_date":"2026-06-15T08:34:33.830935","created_date":"2026-03-08T00:00:00"}