{"id":"https://openalex.org/W3112711027","doi":"https://doi.org/10.1016/j.gpb.2020.06.004","title":"The mRNA Binding Proteome of Proliferating and Differentiated Muscle Cells","display_name":"The mRNA Binding Proteome of Proliferating and Differentiated Muscle Cells","publication_year":2020,"publication_date":"2020-08-01","ids":{"openalex":"https://openalex.org/W3112711027","doi":"https://doi.org/10.1016/j.gpb.2020.06.004","mag":"3112711027","pmid":"https://pubmed.ncbi.nlm.nih.gov/33338663"},"language":"en","primary_location":{"id":"doi:10.1016/j.gpb.2020.06.004","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.gpb.2020.06.004","pdf_url":null,"source":{"id":"https://openalex.org/S155547894","display_name":"Genomics Proteomics & Bioinformatics","issn_l":"1672-0229","issn":["1672-0229","2210-3244"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genomics, Proteomics & Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1016/j.gpb.2020.06.004","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026538428","display_name":"Monika Hiller","orcid":"https://orcid.org/0000-0003-3420-5840"},"institutions":[{"id":"https://openalex.org/I2800006345","display_name":"Leiden University Medical Center","ror":"https://ror.org/05xvt9f17","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2800006345"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Monika Hiller","raw_affiliation_strings":["Department of Human Genetics, Leiden University Medical Center , Leiden 2333 ZC , the Netherlands"],"raw_orcid":"https://orcid.org/0000-0003-3420-5840","affiliations":[{"raw_affiliation_string":"Department of Human Genetics, Leiden University Medical Center , Leiden 2333 ZC , the Netherlands","institution_ids":["https://openalex.org/I2800006345"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023581779","display_name":"M Geissler","orcid":"https://orcid.org/0000-0002-2939-4838"},"institutions":[{"id":"https://openalex.org/I2800006345","display_name":"Leiden University Medical Center","ror":"https://ror.org/05xvt9f17","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2800006345"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Miriam Geissler","raw_affiliation_strings":["Department of Human Genetics, Leiden University Medical Center , Leiden 2333 ZC , the Netherlands"],"raw_orcid":"https://orcid.org/0000-0002-2939-4838","affiliations":[{"raw_affiliation_string":"Department of Human Genetics, Leiden University Medical Center , Leiden 2333 ZC , the Netherlands","institution_ids":["https://openalex.org/I2800006345"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035823763","display_name":"George M. C. Janssen","orcid":"https://orcid.org/0000-0001-9091-4030"},"institutions":[{"id":"https://openalex.org/I2800006345","display_name":"Leiden University Medical Center","ror":"https://ror.org/05xvt9f17","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2800006345"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"George Janssen","raw_affiliation_strings":["Center for Proteomics and Metabolomics, Leiden University Medical Center , Leiden 2333 ZC , the Netherlands"],"raw_orcid":"https://orcid.org/0000-0001-9091-4030","affiliations":[{"raw_affiliation_string":"Center for Proteomics and Metabolomics, Leiden University Medical Center , Leiden 2333 ZC , the Netherlands","institution_ids":["https://openalex.org/I2800006345"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014860636","display_name":"Peter A. van Veelen","orcid":"https://orcid.org/0000-0002-7898-9408"},"institutions":[{"id":"https://openalex.org/I2800006345","display_name":"Leiden University Medical Center","ror":"https://ror.org/05xvt9f17","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2800006345"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Peter van Veelen","raw_affiliation_strings":["Center for Proteomics and Metabolomics, Leiden University Medical Center , Leiden 2333 ZC , the Netherlands"],"raw_orcid":"https://orcid.org/0000-0002-7898-9408","affiliations":[{"raw_affiliation_string":"Center for Proteomics and Metabolomics, Leiden University Medical Center , Leiden 2333 ZC , the Netherlands","institution_ids":["https://openalex.org/I2800006345"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033643112","display_name":"Annemieke Aartsma\u2010Rus","orcid":"https://orcid.org/0000-0003-1565-654X"},"institutions":[{"id":"https://openalex.org/I2800006345","display_name":"Leiden University Medical Center","ror":"https://ror.org/05xvt9f17","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2800006345"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Annemieke Aartsma-Rus","raw_affiliation_strings":["Department of Human Genetics, Leiden University Medical Center , Leiden 2333 ZC , the Netherlands"],"raw_orcid":"https://orcid.org/0000-0003-1565-654X","affiliations":[{"raw_affiliation_string":"Department of Human Genetics, Leiden University Medical Center , Leiden 2333 ZC , the Netherlands","institution_ids":["https://openalex.org/I2800006345"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065528743","display_name":"Pietro Spitali","orcid":"https://orcid.org/0000-0003-2783-688X"},"institutions":[{"id":"https://openalex.org/I2800006345","display_name":"Leiden University Medical Center","ror":"https://ror.org/05xvt9f17","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2800006345"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"Pietro Spitali","raw_affiliation_strings":["Department of Human Genetics, Leiden University Medical Center , Leiden 2333 ZC , the Netherlands"],"raw_orcid":"https://orcid.org/0000-0003-2783-688X","affiliations":[{"raw_affiliation_string":"Department of Human Genetics, Leiden University Medical Center , Leiden 2333 ZC , the Netherlands","institution_ids":["https://openalex.org/I2800006345"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5065528743"],"corresponding_institution_ids":["https://openalex.org/I2800006345"],"apc_list":{"value":3500,"currency":"USD","value_usd":3500},"apc_paid":{"value":3500,"currency":"USD","value_usd":3500},"fwci":0.418,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.61346838,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"18","issue":"4","first_page":"384","last_page":"396"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/myogenesis","display_name":"Myogenesis","score":0.883126974105835},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.6881492137908936},{"id":"https://openalex.org/keywords/rna-binding-protein","display_name":"RNA-binding protein","score":0.6302071809768677},{"id":"https://openalex.org/keywords/interactome","display_name":"Interactome","score":0.6288520097732544},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.6086853742599487},{"id":"https://openalex.org/keywords/cell-biology","display_name":"Cell biology","score":0.5890673398971558},{"id":"https://openalex.org/keywords/messenger-rna","display_name":"Messenger RNA","score":0.5731505155563354},{"id":"https://openalex.org/keywords/myocyte","display_name":"Myocyte","score":0.5721233487129211},{"id":"https://openalex.org/keywords/proteome","display_name":"Proteome","score":0.5720332264900208},{"id":"https://openalex.org/keywords/transcriptome","display_name":"Transcriptome","score":0.5148657560348511},{"id":"https://openalex.org/keywords/multinucleate","display_name":"Multinucleate","score":0.49520793557167053},{"id":"https://openalex.org/keywords/rna","display_name":"RNA","score":0.489879310131073},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.4518706798553467},{"id":"https://openalex.org/keywords/regulation-of-gene-expression","display_name":"Regulation of gene expression","score":0.4214871823787689},{"id":"https://openalex.org/keywords/molecular-biology","display_name":"Molecular biology","score":0.36192068457603455},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.2723202109336853}],"concepts":[{"id":"https://openalex.org/C3763915","wikidata":"https://www.wikidata.org/wiki/Q3331437","display_name":"Myogenesis","level":3,"score":0.883126974105835},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6881492137908936},{"id":"https://openalex.org/C41282012","wikidata":"https://www.wikidata.org/wiki/Q3928341","display_name":"RNA-binding protein","level":4,"score":0.6302071809768677},{"id":"https://openalex.org/C9760119","wikidata":"https://www.wikidata.org/wiki/Q841382","display_name":"Interactome","level":3,"score":0.6288520097732544},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.6086853742599487},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5890673398971558},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.5731505155563354},{"id":"https://openalex.org/C207200792","wikidata":"https://www.wikidata.org/wiki/Q428914","display_name":"Myocyte","level":2,"score":0.5721233487129211},{"id":"https://openalex.org/C104397665","wikidata":"https://www.wikidata.org/wiki/Q860947","display_name":"Proteome","level":2,"score":0.5720332264900208},{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.5148657560348511},{"id":"https://openalex.org/C136403682","wikidata":"https://www.wikidata.org/wiki/Q5796041","display_name":"Multinucleate","level":2,"score":0.49520793557167053},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.489879310131073},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4518706798553467},{"id":"https://openalex.org/C165864922","wikidata":"https://www.wikidata.org/wiki/Q411391","display_name":"Regulation of gene expression","level":3,"score":0.4214871823787689},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.36192068457603455},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2723202109336853}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016601","descriptor_name":"RNA-Binding Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D016601","descriptor_name":"RNA-Binding Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D016601","descriptor_name":"RNA-Binding Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D032383","descriptor_name":"Myocytes, Cardiac","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D032383","descriptor_name":"Myocytes, Cardiac","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D032383","descriptor_name":"Myocytes, Cardiac","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.gpb.2020.06.004","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.gpb.2020.06.004","pdf_url":null,"source":{"id":"https://openalex.org/S155547894","display_name":"Genomics Proteomics & Bioinformatics","issn_l":"1672-0229","issn":["1672-0229","2210-3244"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genomics, Proteomics & Bioinformatics","raw_type":"journal-article"},{"id":"pmid:33338663","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33338663","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genomics, proteomics & bioinformatics","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:8242265","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8242265","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Genomics Proteomics Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1016/j.gpb.2020.06.004","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.gpb.2020.06.004","pdf_url":null,"source":{"id":"https://openalex.org/S155547894","display_name":"Genomics Proteomics & Bioinformatics","issn_l":"1672-0229","issn":["1672-0229","2210-3244"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genomics, Proteomics & Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G8126811831","display_name":null,"funder_award_id":"W.OR.14-13","funder_id":"https://openalex.org/F4320322485","funder_display_name":"Prinses Beatrix Spierfonds"}],"funders":[{"id":"https://openalex.org/F4320322485","display_name":"Prinses Beatrix Spierfonds","ror":"https://ror.org/0011f2t53"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":38,"referenced_works":["https://openalex.org/W1212882679","https://openalex.org/W1974283636","https://openalex.org/W1984574291","https://openalex.org/W1986911150","https://openalex.org/W1990590627","https://openalex.org/W1997535872","https://openalex.org/W2004552697","https://openalex.org/W2004905782","https://openalex.org/W2009271040","https://openalex.org/W2025075195","https://openalex.org/W2031371243","https://openalex.org/W2033253992","https://openalex.org/W2041440237","https://openalex.org/W2054062816","https://openalex.org/W2069799701","https://openalex.org/W2073737981","https://openalex.org/W2102565806","https://openalex.org/W2124729117","https://openalex.org/W2125368134","https://openalex.org/W2135709931","https://openalex.org/W2141826410","https://openalex.org/W2146162156","https://openalex.org/W2149697028","https://openalex.org/W2153276140","https://openalex.org/W2164308667","https://openalex.org/W2179438025","https://openalex.org/W2242206668","https://openalex.org/W2256899852","https://openalex.org/W2415443076","https://openalex.org/W2487752912","https://openalex.org/W2754553258","https://openalex.org/W2766268399","https://openalex.org/W2785329615","https://openalex.org/W2794416695","https://openalex.org/W2802855982","https://openalex.org/W2899760200","https://openalex.org/W2900569176","https://openalex.org/W3083187548"],"related_works":["https://openalex.org/W1986516907","https://openalex.org/W2088599948","https://openalex.org/W2293272278","https://openalex.org/W3157357317","https://openalex.org/W2167885378","https://openalex.org/W2086768887","https://openalex.org/W4313644653","https://openalex.org/W2999997950","https://openalex.org/W1988257487","https://openalex.org/W1977095634"],"abstract_inverted_index":{"Muscle":[0],"formation":[1],"is":[2],"a":[3],"coordinated":[4],"process":[5],"driven":[6],"by":[7,28,50],"extensive":[8],"gene":[9,42],"expression":[10,43,67],"changes":[11,44],"where":[12],"single":[13],"cells":[14,56],"fuse":[15],"together":[16],"to":[17,105,127],"form":[18],"multinucleated":[19],"muscle":[20,55],"fibers.":[21],"Newly":[22],"synthesized":[23],"mRNAs":[24,111,128],"are":[25],"then":[26],"regulated":[27],"RNA":[29,134,171],"binding":[30,135],"proteins":[31,124],"(RBPs),":[32],"affecting":[33],"post-transcriptional":[34],"transcript":[35],"metabolism.":[36],"Here,":[37],"we":[38,138],"determined":[39],"how":[40,140,162],"large-scale":[41],"affect":[45],"the":[46,66,141,147],"catalog":[47],"of":[48,68,81,95,99,122,143,149],"RBPs":[49,97,145],"studying":[51],"proliferating":[52],"and":[53,59,86],"differentiated":[54],"in":[57,112],"healthy":[58,154],"dystrophic":[60,157],"conditions.":[61],"Transcriptomic":[62],"analysis":[63],"showed":[64,139],"that":[65,151,179],"more":[69],"than":[70],"7000":[71],"genes":[72],"was":[73,103],"affected":[74],"during":[75],"myogenesis.":[76],"We":[77],"identified":[78],"769":[79],"RBPs,":[80],"which":[82,100],"294":[83],"were":[84,88,101,125],"muscle-specific":[85],"49":[87],"uniquely":[89],"shared":[90],"with":[91,109],"cardiomyocytes.":[92],"A":[93,119],"subset":[94],"32":[96],"(half":[98],"muscle-specific)":[102],"found":[104],"be":[106,181],"preferentially":[107],"associated":[108],"target":[110],"either":[113],"myoblasts":[114],"(MBs)":[115],"or":[116],"myotubes":[117],"(MTs).":[118],"large":[120],"proportion":[121],"catalytic":[123],"bound":[126],"even":[129],"though":[130],"they":[131],"lack":[132],"classical":[133],"domains.":[136],"Finally,":[137],"identification":[142,148],"cell-specific":[144,177],"enabled":[146],"biomarkers":[150],"can":[152,165,180],"separate":[153],"individuals":[155],"from":[156],"patients.":[158],"Our":[159],"data":[160,164,178],"show":[161],"interactome":[163],"shed":[166],"light":[167],"on":[168],"new":[169],"basic":[170],"biology":[172],"as":[173,175],"well":[174],"provide":[176],"used":[182],"for":[183],"diagnostic":[184],"purposes.":[185]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3}],"updated_date":"2026-03-27T05:58:40.876381","created_date":"2025-10-10T00:00:00"}