{"id":"https://openalex.org/W4399993608","doi":"https://doi.org/10.1016/j.compbiomed.2024.108618","title":"CAS3D: 3D quantitative morphometry on Second Harmonic Generation image volumes from single skeletal muscle fibers","display_name":"CAS3D: 3D quantitative morphometry on Second Harmonic Generation image volumes from single skeletal muscle fibers","publication_year":2024,"publication_date":"2024-06-25","ids":{"openalex":"https://openalex.org/W4399993608","doi":"https://doi.org/10.1016/j.compbiomed.2024.108618","pmid":"https://pubmed.ncbi.nlm.nih.gov/38925088"},"language":"en","primary_location":{"id":"doi:10.1016/j.compbiomed.2024.108618","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1016/j.compbiomed.2024.108618","pdf_url":null,"source":{"id":"https://openalex.org/S44278595","display_name":"Computers in Biology and Medicine","issn_l":"0010-4825","issn":["0010-4825","1879-0534"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computers in Biology and Medicine","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"http://dx.doi.org/10.1016/j.compbiomed.2024.108618","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071837046","display_name":"Dominik Schneidereit","orcid":"https://orcid.org/0000-0001-7351-6428"},"institutions":[{"id":"https://openalex.org/I181369854","display_name":"Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg","ror":"https://ror.org/00f7hpc57","country_code":"DE","type":"education","lineage":["https://openalex.org/I181369854"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Dominik Schneidereit","raw_affiliation_strings":["Institute of Medical Biotechnology, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, Paul-Gordan-Strasse 3, 91052 Erlangn, Germany. Electronic address: dominik.schneidereit@fau.de","Institute of Medical Biotechnology, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, Paul-Gordan-Strasse 3, 91052 Erlangn, Germany"],"raw_orcid":"https://orcid.org/0000-0001-7351-6428","affiliations":[{"raw_affiliation_string":"Institute of Medical Biotechnology, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, Paul-Gordan-Strasse 3, 91052 Erlangn, Germany. Electronic address: dominik.schneidereit@fau.de","institution_ids":["https://openalex.org/I181369854"]},{"raw_affiliation_string":"Institute of Medical Biotechnology, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, Paul-Gordan-Strasse 3, 91052 Erlangn, Germany","institution_ids":["https://openalex.org/I181369854"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114181614","display_name":"Julian Bauer","orcid":null},"institutions":[{"id":"https://openalex.org/I181369854","display_name":"Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg","ror":"https://ror.org/00f7hpc57","country_code":"DE","type":"education","lineage":["https://openalex.org/I181369854"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Julian Bauer","raw_affiliation_strings":["Institute of Medical Biotechnology, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, Paul-Gordan-Strasse 3, 91052 Erlangn, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Medical Biotechnology, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, Paul-Gordan-Strasse 3, 91052 Erlangn, Germany","institution_ids":["https://openalex.org/I181369854"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092355003","display_name":"Sofia Mnuskina","orcid":null},"institutions":[{"id":"https://openalex.org/I181369854","display_name":"Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg","ror":"https://ror.org/00f7hpc57","country_code":"DE","type":"education","lineage":["https://openalex.org/I181369854"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Sofia Mnuskina","raw_affiliation_strings":["Institute of Medical Biotechnology, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, Paul-Gordan-Strasse 3, 91052 Erlangn, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Medical Biotechnology, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, Paul-Gordan-Strasse 3, 91052 Erlangn, Germany","institution_ids":["https://openalex.org/I181369854"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041892010","display_name":"Stefanie N\u00fcbler","orcid":null},"institutions":[{"id":"https://openalex.org/I181369854","display_name":"Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg","ror":"https://ror.org/00f7hpc57","country_code":"DE","type":"education","lineage":["https://openalex.org/I181369854"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Stefanie N\u00fcbler","raw_affiliation_strings":["Medical Faculty, IPASUM, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, Kochstrasse 19, 91054 Erlangen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Faculty, IPASUM, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, Kochstrasse 19, 91054 Erlangen, Germany","institution_ids":["https://openalex.org/I181369854"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043560792","display_name":"Nicola Cacciani","orcid":"https://orcid.org/0000-0002-0373-7249"},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Nicola Cacciani","raw_affiliation_strings":["Department of Physiology and Pharmacology, Karolinska Institutet, Solnavaegen 30, 17164 Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Pharmacology, Karolinska Institutet, Solnavaegen 30, 17164 Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011400986","display_name":"Alexander M\u00fchlberg","orcid":"https://orcid.org/0000-0001-8039-844X"},"institutions":[{"id":"https://openalex.org/I181369854","display_name":"Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg","ror":"https://ror.org/00f7hpc57","country_code":"DE","type":"education","lineage":["https://openalex.org/I181369854"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Alexander M\u00fchlberg","raw_affiliation_strings":["Institute of Medical Biotechnology, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, Paul-Gordan-Strasse 3, 91052 Erlangn, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Medical Biotechnology, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, Paul-Gordan-Strasse 3, 91052 Erlangn, Germany","institution_ids":["https://openalex.org/I181369854"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021627864","display_name":"Lucas Krei\u00df","orcid":"https://orcid.org/0000-0002-7749-0015"},"institutions":[{"id":"https://openalex.org/I181369854","display_name":"Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg","ror":"https://ror.org/00f7hpc57","country_code":"DE","type":"education","lineage":["https://openalex.org/I181369854"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Lucas Kreiss","raw_affiliation_strings":["Institute of Medical Biotechnology, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, Paul-Gordan-Strasse 3, 91052 Erlangn, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Medical Biotechnology, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, Paul-Gordan-Strasse 3, 91052 Erlangn, Germany","institution_ids":["https://openalex.org/I181369854"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114181616","display_name":"Paul Ritter","orcid":null},"institutions":[{"id":"https://openalex.org/I181369854","display_name":"Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg","ror":"https://ror.org/00f7hpc57","country_code":"DE","type":"education","lineage":["https://openalex.org/I181369854"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Paul Ritter","raw_affiliation_strings":["Institute of Medical Biotechnology, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, Paul-Gordan-Strasse 3, 91052 Erlangn, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Medical Biotechnology, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, Paul-Gordan-Strasse 3, 91052 Erlangn, Germany","institution_ids":["https://openalex.org/I181369854"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007241569","display_name":"Sebastian Sch\u00fcrmann","orcid":"https://orcid.org/0000-0001-6497-9754"},"institutions":[{"id":"https://openalex.org/I181369854","display_name":"Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg","ror":"https://ror.org/00f7hpc57","country_code":"DE","type":"education","lineage":["https://openalex.org/I181369854"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Sebastian Sch\u00fcrmann","raw_affiliation_strings":["Institute of Medical Biotechnology, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, Paul-Gordan-Strasse 3, 91052 Erlangn, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Medical Biotechnology, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, Paul-Gordan-Strasse 3, 91052 Erlangn, Germany","institution_ids":["https://openalex.org/I181369854"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114181613","display_name":"Lars Larsson","orcid":null},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Lars Larsson","raw_affiliation_strings":["Department of Physiology and Pharmacology, Karolinska Institutet, Solnavaegen 30, 17164 Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Pharmacology, Karolinska Institutet, Solnavaegen 30, 17164 Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5055086920","display_name":"Oliver Friedrich","orcid":"https://orcid.org/0000-0003-2238-2049"},"institutions":[{"id":"https://openalex.org/I181369854","display_name":"Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg","ror":"https://ror.org/00f7hpc57","country_code":"DE","type":"education","lineage":["https://openalex.org/I181369854"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Oliver Friedrich","raw_affiliation_strings":["Institute of Medical Biotechnology, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, Paul-Gordan-Strasse 3, 91052 Erlangn, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Medical Biotechnology, Friedrich-Alexander Universit\u00e4t Erlangen-N\u00fcrnberg, Paul-Gordan-Strasse 3, 91052 Erlangn, Germany","institution_ids":["https://openalex.org/I181369854"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":11,"corresponding_author_ids":["https://openalex.org/A5071837046"],"corresponding_institution_ids":["https://openalex.org/I181369854"],"apc_list":{"value":2610,"currency":"USD","value_usd":2610},"apc_paid":{"value":2610,"currency":"USD","value_usd":2610},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.11945754,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"178","issue":null,"first_page":"108618","last_page":"108618"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11861","display_name":"Thermal Regulation in Medicine","score":0.9983999729156494,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11861","display_name":"Thermal Regulation in Medicine","score":0.9983999729156494,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10867","display_name":"Intensive Care Unit Cognitive Disorders","score":0.9937999844551086,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10322","display_name":"Respiratory Support and Mechanisms","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sarcomere","display_name":"Sarcomere","score":0.49325650930404663},{"id":"https://openalex.org/keywords/noise","display_name":"Noise (video)","score":0.48366889357566833},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.4824260175228119},{"id":"https://openalex.org/keywords/orientation","display_name":"Orientation (vector space)","score":0.4518749415874481},{"id":"https://openalex.org/keywords/skeletal-muscle","display_name":"Skeletal muscle","score":0.4517969787120819},{"id":"https://openalex.org/keywords/image-processing","display_name":"Image processing","score":0.4454805254936218},{"id":"https://openalex.org/keywords/pixel","display_name":"Pixel","score":0.4187888503074646},{"id":"https://openalex.org/keywords/fast-fourier-transform","display_name":"Fast Fourier transform","score":0.41742128133773804},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.41060879826545715},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.37869444489479065},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.37668538093566895},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.23836177587509155},{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.2151685357093811},{"id":"https://openalex.org/keywords/anatomy","display_name":"Anatomy","score":0.18940481543540955},{"id":"https://openalex.org/keywords/geometry","display_name":"Geometry","score":0.148483008146286},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.13653457164764404}],"concepts":[{"id":"https://openalex.org/C68731436","wikidata":"https://www.wikidata.org/wiki/Q1337087","display_name":"Sarcomere","level":3,"score":0.49325650930404663},{"id":"https://openalex.org/C99498987","wikidata":"https://www.wikidata.org/wiki/Q2210247","display_name":"Noise (video)","level":3,"score":0.48366889357566833},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.4824260175228119},{"id":"https://openalex.org/C16345878","wikidata":"https://www.wikidata.org/wiki/Q107472979","display_name":"Orientation (vector space)","level":2,"score":0.4518749415874481},{"id":"https://openalex.org/C2779959927","wikidata":"https://www.wikidata.org/wiki/Q1048687","display_name":"Skeletal muscle","level":2,"score":0.4517969787120819},{"id":"https://openalex.org/C9417928","wikidata":"https://www.wikidata.org/wiki/Q1070689","display_name":"Image processing","level":3,"score":0.4454805254936218},{"id":"https://openalex.org/C160633673","wikidata":"https://www.wikidata.org/wiki/Q355198","display_name":"Pixel","level":2,"score":0.4187888503074646},{"id":"https://openalex.org/C75172450","wikidata":"https://www.wikidata.org/wiki/Q623950","display_name":"Fast Fourier transform","level":2,"score":0.41742128133773804},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.41060879826545715},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.37869444489479065},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.37668538093566895},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.23836177587509155},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.2151685357093811},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.18940481543540955},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.148483008146286},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.13653457164764404},{"id":"https://openalex.org/C207200792","wikidata":"https://www.wikidata.org/wiki/Q428914","display_name":"Myocyte","level":2,"score":0.0},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018485","descriptor_name":"Muscle Fibers, Skeletal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018485","descriptor_name":"Muscle Fibers, Skeletal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018485","descriptor_name":"Muscle Fibers, Skeletal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018485","descriptor_name":"Muscle Fibers, Skeletal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.compbiomed.2024.108618","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1016/j.compbiomed.2024.108618","pdf_url":null,"source":{"id":"https://openalex.org/S44278595","display_name":"Computers in Biology and Medicine","issn_l":"0010-4825","issn":["0010-4825","1879-0534"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computers in Biology and Medicine","raw_type":"journal-article"},{"id":"pmid:38925088","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38925088","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computers in biology and medicine","raw_type":null}],"best_oa_location":{"id":"doi:10.1016/j.compbiomed.2024.108618","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1016/j.compbiomed.2024.108618","pdf_url":null,"source":{"id":"https://openalex.org/S44278595","display_name":"Computers in Biology and Medicine","issn_l":"0010-4825","issn":["0010-4825","1879-0534"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computers in Biology and Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.4000000059604645,"display_name":"Affordable and clean energy","id":"https://metadata.un.org/sdg/7"}],"awards":[{"id":"https://openalex.org/G1147110907","display_name":null,"funder_award_id":"326998133 - TRR 225","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"}],"funders":[{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W1971450283","https://openalex.org/W1973406918","https://openalex.org/W1973913388","https://openalex.org/W1977569636","https://openalex.org/W1991762031","https://openalex.org/W2091955873","https://openalex.org/W2098108992","https://openalex.org/W2103409944","https://openalex.org/W2138449751","https://openalex.org/W2167279371","https://openalex.org/W2299783208","https://openalex.org/W2315387611","https://openalex.org/W2483242034","https://openalex.org/W2787983500","https://openalex.org/W2886306865","https://openalex.org/W2895961551","https://openalex.org/W3112055137","https://openalex.org/W3121756771","https://openalex.org/W3154932288","https://openalex.org/W4296352487","https://openalex.org/W4382468547","https://openalex.org/W4385851871","https://openalex.org/W6747943097","https://openalex.org/W6851880486"],"related_works":["https://openalex.org/W3015009692","https://openalex.org/W2169837375","https://openalex.org/W2082542487","https://openalex.org/W2125755819","https://openalex.org/W1585440942","https://openalex.org/W1577214112","https://openalex.org/W1985023586","https://openalex.org/W4390749930","https://openalex.org/W2399286426","https://openalex.org/W2054188149"],"abstract_inverted_index":{"The":[0,68,112,140],"CAS3D":[1,70,89],"image":[2,33,157],"processing":[3],"method":[4,185,237],"intuitively":[5],"applies":[6],"a":[7,103,107,145,160,210],"combination":[8],"of":[9,21,52,109,150,167,190,199,212,238],"Fourier":[10],"space":[11,14],"and":[12,65,91,116,123,128,194],"real":[13],"3D":[15,56,230],"analysis":[16,222],"algorithms":[17,223],"to":[18,144,214,224,233],"volumetric":[19,155,227],"images":[20,85,228],"single":[22,151],"skeletal":[23,152],"muscle":[24,44,153],"fiber":[25,154],"Myosin":[26],"II":[27],"Second":[28],"Harmonic":[29],"Generation":[30],"(SHG)":[31],"XYZ":[32],"data.":[34],"Our":[35,184],"developed":[36],"tool":[37],"automatically":[38],"quantifies":[39],"the":[40,48,60,87,97,176,188,191,196,200,225,234],"myofibrillar":[41],"orientation":[42,117],"in":[43,55,83,114,205,229,231],"samples":[45],"by":[46,102,220],"determining":[47,59],"cosine":[49,201],"angle":[50,202],"sum":[51,203],"intensity":[53],"gradients":[54],"(CAS3D)":[57],"while":[58],"mean":[61,211],"sarcomere":[62],"length":[63],"(SL)":[64],"sample":[66,207],"orientation.":[67],"expected":[69],"values":[71],"could":[72],"be":[73,100],"reproduced":[74,187],"from":[75,132,159,209],"ideal":[76,122],"artificial":[77,84,125],"data":[78,126,148,158],"sets.":[79],"Applied":[80],"random":[81],"noise":[82,93],"lowers":[86],"detected":[88],"value,":[90],"for":[92],"levels":[94],"below":[95],"20%,":[96],"correlation":[98],"can":[99],"approximated":[101],"linear":[104],"function":[105],"with":[106,172],"slope":[108],"-0.006":[110],"CAS3D/noise%.":[111],"deviations":[113],"SL":[115],"detection":[118,204],"were":[119,129],"determined":[120],"on":[121],"noisy":[124],"sets":[127],"statistically":[130],"indistinguishable":[131],"0":[133],"(null":[134],"hypothesis":[135],"t-test":[136],"P":[137],">":[138],"0.1).":[139],"software":[141],"was":[142],"applied":[143],"previously":[146,235],"published":[147],"set":[149],"SHG":[156],"rat":[161],"intensive":[162],"care":[163],"unit":[164],"(ICU)":[165],"model":[166],"ventilator-induced":[168],"diaphragm":[169],"dysfunction":[170],"(VIDD)":[171],"treatment":[173],"regimens":[174],"involving":[175],"small":[177],"anti-inflammatory":[178],"molecules":[179],"BGP-15,":[180],"vamorolone,":[181],"or":[182],"prednisolone.":[183],"reliably":[186],"results":[189],"previous":[192],"work":[193],"improved":[195],"standard":[197],"deviation":[198],"all":[206],"groups":[208],"0.03":[213],"0.008.":[215],"This":[216],"improvement":[217],"is":[218],"achieved":[219],"applying":[221],"whole":[226],"contrast":[232],"common":[236],"slice-wise":[239],"XY":[240],"analysis.":[241]},"counts_by_year":[],"updated_date":"2026-05-03T08:25:01.440150","created_date":"2025-10-10T00:00:00"}