{"id":"https://openalex.org/W2157475312","doi":"https://doi.org/10.1016/j.compbiomed.2004.12.002","title":"Automatic detection of unstained viable cells in bright field images using a support vector machine with an improved training procedure","display_name":"Automatic detection of unstained viable cells in bright field images using a support vector machine with an improved training procedure","publication_year":2005,"publication_date":"2005-03-23","ids":{"openalex":"https://openalex.org/W2157475312","doi":"https://doi.org/10.1016/j.compbiomed.2004.12.002","mag":"2157475312","pmid":"https://pubmed.ncbi.nlm.nih.gov/16488772"},"language":"en","primary_location":{"id":"doi:10.1016/j.compbiomed.2004.12.002","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.compbiomed.2004.12.002","pdf_url":null,"source":{"id":"https://openalex.org/S44278595","display_name":"Computers in Biology and Medicine","issn_l":"0010-4825","issn":["0010-4825","1879-0534"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computers in Biology and Medicine","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068231985","display_name":"Xi Long","orcid":"https://orcid.org/0000-0001-9505-1270"},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xi Long","raw_affiliation_strings":["Mechanical Engineering Department, Columbia University, 500 West 120th Street, 220 Mudd. MC 4703, New York, NY 10027, USA"],"affiliations":[{"raw_affiliation_string":"Mechanical Engineering Department, Columbia University, 500 West 120th Street, 220 Mudd. MC 4703, New York, NY 10027, USA","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064104730","display_name":"Louis Cleveland","orcid":null},"institutions":[{"id":"https://openalex.org/I1321572752","display_name":"St. Luke's-Roosevelt Hospital Center","ror":"https://ror.org/011t2cn48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1321572752"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Louis Cleveland","raw_affiliation_strings":["Department of Medicine at St. Luke's Roosevelt Hospital Center and Columbia University, New York, NY 10019, USA"],"affiliations":[{"raw_affiliation_string":"Department of Medicine at St. Luke's Roosevelt Hospital Center and Columbia University, New York, NY 10019, USA","institution_ids":["https://openalex.org/I1321572752","https://openalex.org/I78577930"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5055639208","display_name":"Yachen Yao","orcid":"https://orcid.org/0009-0000-3777-3136"},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Y. Lawrence Yao","raw_affiliation_strings":["Mechanical Engineering Department, Columbia University, 500 West 120th Street, 220 Mudd. MC 4703, New York, NY 10027, USA"],"affiliations":[{"raw_affiliation_string":"Mechanical Engineering Department, Columbia University, 500 West 120th Street, 220 Mudd. MC 4703, New York, NY 10027, USA","institution_ids":["https://openalex.org/I78577930"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5064104730"],"corresponding_institution_ids":["https://openalex.org/I1321572752","https://openalex.org/I78577930"],"apc_list":{"value":2610,"currency":"USD","value_usd":2610},"apc_paid":null,"fwci":2.0562,"has_fulltext":false,"cited_by_count":36,"citation_normalized_percentile":{"value":0.88535088,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"36","issue":"4","first_page":"339","last_page":"362"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12874","display_name":"Digital Imaging for Blood Diseases","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12874","display_name":"Digital Imaging for Blood Diseases","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9973000288009644,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13114","display_name":"Image Processing Techniques and Applications","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2214","display_name":"Media Technology"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/support-vector-machine","display_name":"Support vector machine","score":0.843521237373352},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7301983833312988},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6784185171127319},{"id":"https://openalex.org/keywords/binary-classification","display_name":"Binary classification","score":0.5954328179359436},{"id":"https://openalex.org/keywords/decision-boundary","display_name":"Decision boundary","score":0.5932742357254028},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.5766555666923523},{"id":"https://openalex.org/keywords/binary-number","display_name":"Binary number","score":0.5269095301628113},{"id":"https://openalex.org/keywords/task","display_name":"Task (project management)","score":0.5103372931480408},{"id":"https://openalex.org/keywords/field","display_name":"Field (mathematics)","score":0.4732005298137665},{"id":"https://openalex.org/keywords/boundary","display_name":"Boundary (topology)","score":0.43842872977256775},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.42698484659194946},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.41764697432518005},{"id":"https://openalex.org/keywords/selection","display_name":"Selection (genetic algorithm)","score":0.41144663095474243},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.18036308884620667}],"concepts":[{"id":"https://openalex.org/C12267149","wikidata":"https://www.wikidata.org/wiki/Q282453","display_name":"Support vector machine","level":2,"score":0.843521237373352},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7301983833312988},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6784185171127319},{"id":"https://openalex.org/C66905080","wikidata":"https://www.wikidata.org/wiki/Q17005494","display_name":"Binary classification","level":3,"score":0.5954328179359436},{"id":"https://openalex.org/C42023084","wikidata":"https://www.wikidata.org/wiki/Q5249231","display_name":"Decision boundary","level":3,"score":0.5932742357254028},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.5766555666923523},{"id":"https://openalex.org/C48372109","wikidata":"https://www.wikidata.org/wiki/Q3913","display_name":"Binary number","level":2,"score":0.5269095301628113},{"id":"https://openalex.org/C2780451532","wikidata":"https://www.wikidata.org/wiki/Q759676","display_name":"Task (project management)","level":2,"score":0.5103372931480408},{"id":"https://openalex.org/C9652623","wikidata":"https://www.wikidata.org/wiki/Q190109","display_name":"Field (mathematics)","level":2,"score":0.4732005298137665},{"id":"https://openalex.org/C62354387","wikidata":"https://www.wikidata.org/wiki/Q875399","display_name":"Boundary (topology)","level":2,"score":0.43842872977256775},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.42698484659194946},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.41764697432518005},{"id":"https://openalex.org/C81917197","wikidata":"https://www.wikidata.org/wiki/Q628760","display_name":"Selection (genetic algorithm)","level":2,"score":0.41144663095474243},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.18036308884620667},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0},{"id":"https://openalex.org/C94375191","wikidata":"https://www.wikidata.org/wiki/Q11205","display_name":"Arithmetic","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C202444582","wikidata":"https://www.wikidata.org/wiki/Q837863","display_name":"Pure mathematics","level":1,"score":0.0},{"id":"https://openalex.org/C187736073","wikidata":"https://www.wikidata.org/wiki/Q2920921","display_name":"Management","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D010363","descriptor_name":"Pattern Recognition, Automated","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D016393","descriptor_name":"Lymphoma, B-Cell","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D016393","descriptor_name":"Lymphoma, B-Cell","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D016393","descriptor_name":"Lymphoma, B-Cell","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.compbiomed.2004.12.002","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.compbiomed.2004.12.002","pdf_url":null,"source":{"id":"https://openalex.org/S44278595","display_name":"Computers in Biology and Medicine","issn_l":"0010-4825","issn":["0010-4825","1879-0534"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computers in Biology and Medicine","raw_type":"journal-article"},{"id":"pmid:16488772","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16488772","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computers in biology and medicine","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.7200000286102295,"display_name":"Peace, Justice and strong institutions","id":"https://metadata.un.org/sdg/16"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W156870914","https://openalex.org/W1496612019","https://openalex.org/W1498122790","https://openalex.org/W1512098439","https://openalex.org/W1515915515","https://openalex.org/W1528620860","https://openalex.org/W1540550673","https://openalex.org/W1547701650","https://openalex.org/W1563088657","https://openalex.org/W1576520375","https://openalex.org/W1604938182","https://openalex.org/W1684880136","https://openalex.org/W1986215601","https://openalex.org/W2047600618","https://openalex.org/W2056715241","https://openalex.org/W2068059460","https://openalex.org/W2087347434","https://openalex.org/W2095485540","https://openalex.org/W2102794349","https://openalex.org/W2115788596","https://openalex.org/W2116927907","https://openalex.org/W2137346077","https://openalex.org/W2138451337","https://openalex.org/W2139212933","https://openalex.org/W2147817912","https://openalex.org/W2148603752","https://openalex.org/W2164641162","https://openalex.org/W2169590180","https://openalex.org/W2257587576","https://openalex.org/W2913668833","https://openalex.org/W3193477162","https://openalex.org/W4255056905","https://openalex.org/W4285719527","https://openalex.org/W6630527977","https://openalex.org/W6632694911","https://openalex.org/W6662105606","https://openalex.org/W6672247373"],"related_works":["https://openalex.org/W184442817","https://openalex.org/W2009611918","https://openalex.org/W2814966788","https://openalex.org/W2747895175","https://openalex.org/W2946583009","https://openalex.org/W2614669534","https://openalex.org/W2104406636","https://openalex.org/W4310513257","https://openalex.org/W2115788596","https://openalex.org/W2105512057"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":1}],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2025-10-10T00:00:00"}