{"id":"https://openalex.org/W2095176396","doi":"https://doi.org/10.1016/j.camwa.2013.06.026","title":"A mathematical model for immune and autoimmune response mediated by<mml:math xmlns:mml=\"http://www.w3.org/1998/Math/MathML\" altimg=\"si88.gif\" display=\"inline\" overflow=\"scroll\"><mml:mi>T</mml:mi></mml:math>-cells","display_name":"A mathematical model for immune and autoimmune response mediated by<mml:math xmlns:mml=\"http://www.w3.org/1998/Math/MathML\" altimg=\"si88.gif\" display=\"inline\" overflow=\"scroll\"><mml:mi>T</mml:mi></mml:math>-cells","publication_year":2013,"publication_date":"2013-07-31","ids":{"openalex":"https://openalex.org/W2095176396","doi":"https://doi.org/10.1016/j.camwa.2013.06.026","mag":"2095176396"},"language":"en","primary_location":{"id":"doi:10.1016/j.camwa.2013.06.026","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.camwa.2013.06.026","pdf_url":null,"source":{"id":"https://openalex.org/S4210205691","display_name":"Computers & Mathematics with Applications","issn_l":"0898-1221","issn":["0898-1221","1873-7668"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computers &amp; Mathematics with Applications","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061674720","display_name":"Marcello Delitala","orcid":"https://orcid.org/0000-0002-5347-5654"},"institutions":[{"id":"https://openalex.org/I177477856","display_name":"Politecnico di Torino","ror":"https://ror.org/00bgk9508","country_code":"IT","type":"education","lineage":["https://openalex.org/I177477856"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Marcello Delitala","raw_affiliation_strings":["Department of Mathematical Sciences, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129 Torino, Italy"],"affiliations":[{"raw_affiliation_string":"Department of Mathematical Sciences, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129 Torino, Italy","institution_ids":["https://openalex.org/I177477856"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030390675","display_name":"Umberto Dianzani","orcid":"https://orcid.org/0000-0001-6723-3931"},"institutions":[{"id":"https://openalex.org/I123338534","display_name":"Universit\u00e0 degli Studi del Piemonte Orientale \u201cAmedeo Avogadro\u201d","ror":"https://ror.org/04387x656","country_code":"IT","type":"education","lineage":["https://openalex.org/I123338534"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Umberto Dianzani","raw_affiliation_strings":["Department of Health Sciences, \u201cA. Avogadro\u201d Universita del Piemonte Orientale, Via Solaroli 17, 28100 Novara, Italy","Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), \u201cA. Avogadro\u201d Universita del Piemonte Orientale, Via Solaroli 17, 28100 Novara, Italy","Department of Health Sciences, \"A. Avogadro\" Universita del Piemonte Orientale, Via Solaroli 17, 28100 Novara, Italy","Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), \"A. Avogadro\" Universita del Piemonte Orientale, Via Solaroli 17, 28100 Novara, Italy"],"affiliations":[{"raw_affiliation_string":"Department of Health Sciences, \u201cA. Avogadro\u201d Universita del Piemonte Orientale, Via Solaroli 17, 28100 Novara, Italy","institution_ids":["https://openalex.org/I123338534"]},{"raw_affiliation_string":"Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), \u201cA. Avogadro\u201d Universita del Piemonte Orientale, Via Solaroli 17, 28100 Novara, Italy","institution_ids":["https://openalex.org/I123338534"]},{"raw_affiliation_string":"Department of Health Sciences, \"A. Avogadro\" Universita del Piemonte Orientale, Via Solaroli 17, 28100 Novara, Italy","institution_ids":["https://openalex.org/I123338534"]},{"raw_affiliation_string":"Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), \"A. Avogadro\" Universita del Piemonte Orientale, Via Solaroli 17, 28100 Novara, Italy","institution_ids":["https://openalex.org/I123338534"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020270129","display_name":"Tommaso Lorenzi","orcid":"https://orcid.org/0000-0001-9165-1666"},"institutions":[{"id":"https://openalex.org/I177477856","display_name":"Politecnico di Torino","ror":"https://ror.org/00bgk9508","country_code":"IT","type":"education","lineage":["https://openalex.org/I177477856"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Tommaso Lorenzi","raw_affiliation_strings":["Department of Mathematical Sciences, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129 Torino, Italy"],"affiliations":[{"raw_affiliation_string":"Department of Mathematical Sciences, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129 Torino, Italy","institution_ids":["https://openalex.org/I177477856"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5000682679","display_name":"Matteo Melensi","orcid":null},"institutions":[{"id":"https://openalex.org/I123338534","display_name":"Universit\u00e0 degli Studi del Piemonte Orientale \u201cAmedeo Avogadro\u201d","ror":"https://ror.org/04387x656","country_code":"IT","type":"education","lineage":["https://openalex.org/I123338534"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Matteo Melensi","raw_affiliation_strings":["Department of Health Sciences, \u201cA. Avogadro\u201d Universita del Piemonte Orientale, Via Solaroli 17, 28100 Novara, Italy","Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), \u201cA. Avogadro\u201d Universita del Piemonte Orientale, Via Solaroli 17, 28100 Novara, Italy","Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), \"A. Avogadro\" Universita del Piemonte Orientale, Via Solaroli 17, 28100 Novara, Italy","Department of Health Sciences, \"A. Avogadro\" Universita del Piemonte Orientale, Via Solaroli 17, 28100 Novara, Italy"],"affiliations":[{"raw_affiliation_string":"Department of Health Sciences, \u201cA. Avogadro\u201d Universita del Piemonte Orientale, Via Solaroli 17, 28100 Novara, Italy","institution_ids":["https://openalex.org/I123338534"]},{"raw_affiliation_string":"Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), \u201cA. Avogadro\u201d Universita del Piemonte Orientale, Via Solaroli 17, 28100 Novara, Italy","institution_ids":["https://openalex.org/I123338534"]},{"raw_affiliation_string":"Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), \"A. Avogadro\" Universita del Piemonte Orientale, Via Solaroli 17, 28100 Novara, Italy","institution_ids":["https://openalex.org/I123338534"]},{"raw_affiliation_string":"Department of Health Sciences, \"A. Avogadro\" Universita del Piemonte Orientale, Via Solaroli 17, 28100 Novara, Italy","institution_ids":["https://openalex.org/I123338534"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5061674720"],"corresponding_institution_ids":["https://openalex.org/I177477856"],"apc_list":{"value":3480,"currency":"USD","value_usd":3480},"apc_paid":null,"fwci":0.5879,"has_fulltext":false,"cited_by_count":30,"citation_normalized_percentile":{"value":0.69288137,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"66","issue":"6","first_page":"1010","last_page":"1023"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11020","display_name":"Immune Cell Function and Interaction","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11020","display_name":"Immune Cell Function and Interaction","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11016","display_name":"Monoclonal and Polyclonal Antibodies Research","score":0.994700014591217,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/molecular-mimicry","display_name":"Molecular mimicry","score":0.6106135845184326},{"id":"https://openalex.org/keywords/antigen","display_name":"Antigen","score":0.5370257496833801},{"id":"https://openalex.org/keywords/ordinary-differential-equation","display_name":"Ordinary differential equation","score":0.5220184922218323},{"id":"https://openalex.org/keywords/autoimmunity","display_name":"Autoimmunity","score":0.5130144953727722},{"id":"https://openalex.org/keywords/immune-system","display_name":"Immune system","score":0.49677449464797974},{"id":"https://openalex.org/keywords/autoimmune-lymphoproliferative-syndrome","display_name":"Autoimmune lymphoproliferative syndrome","score":0.4592025876045227},{"id":"https://openalex.org/keywords/consistency","display_name":"Consistency (knowledge bases)","score":0.4470222592353821},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.43369874358177185},{"id":"https://openalex.org/keywords/differential-equation","display_name":"Differential equation","score":0.3895912170410156},{"id":"https://openalex.org/keywords/applied-mathematics","display_name":"Applied mathematics","score":0.38188186287879944},{"id":"https://openalex.org/keywords/immunology","display_name":"Immunology","score":0.33299151062965393},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.32385605573654175},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.28770098090171814},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.23875084519386292},{"id":"https://openalex.org/keywords/discrete-mathematics","display_name":"Discrete mathematics","score":0.23439982533454895},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.17372992634773254},{"id":"https://openalex.org/keywords/mathematical-analysis","display_name":"Mathematical analysis","score":0.16786310076713562}],"concepts":[{"id":"https://openalex.org/C2777119779","wikidata":"https://www.wikidata.org/wiki/Q963278","display_name":"Molecular mimicry","level":3,"score":0.6106135845184326},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.5370257496833801},{"id":"https://openalex.org/C51544822","wikidata":"https://www.wikidata.org/wiki/Q465274","display_name":"Ordinary differential equation","level":3,"score":0.5220184922218323},{"id":"https://openalex.org/C2780130043","wikidata":"https://www.wikidata.org/wiki/Q192360","display_name":"Autoimmunity","level":3,"score":0.5130144953727722},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.49677449464797974},{"id":"https://openalex.org/C2778959938","wikidata":"https://www.wikidata.org/wiki/Q1151300","display_name":"Autoimmune lymphoproliferative syndrome","level":5,"score":0.4592025876045227},{"id":"https://openalex.org/C2776436953","wikidata":"https://www.wikidata.org/wiki/Q5163215","display_name":"Consistency (knowledge bases)","level":2,"score":0.4470222592353821},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.43369874358177185},{"id":"https://openalex.org/C78045399","wikidata":"https://www.wikidata.org/wiki/Q11214","display_name":"Differential equation","level":2,"score":0.3895912170410156},{"id":"https://openalex.org/C28826006","wikidata":"https://www.wikidata.org/wiki/Q33521","display_name":"Applied mathematics","level":1,"score":0.38188186287879944},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.33299151062965393},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.32385605573654175},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.28770098090171814},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.23875084519386292},{"id":"https://openalex.org/C118615104","wikidata":"https://www.wikidata.org/wiki/Q121416","display_name":"Discrete mathematics","level":1,"score":0.23439982533454895},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.17372992634773254},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.16786310076713562},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.0},{"id":"https://openalex.org/C31573885","wikidata":"https://www.wikidata.org/wiki/Q304484","display_name":"Programmed cell death","level":3,"score":0.0},{"id":"https://openalex.org/C3031857","wikidata":"https://www.wikidata.org/wiki/Q1649375","display_name":"Fas receptor","level":4,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.camwa.2013.06.026","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.camwa.2013.06.026","pdf_url":null,"source":{"id":"https://openalex.org/S4210205691","display_name":"Computers & Mathematics with Applications","issn_l":"0898-1221","issn":["0898-1221","1873-7668"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computers &amp; Mathematics with Applications","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":38,"referenced_works":["https://openalex.org/W1540294802","https://openalex.org/W1674162913","https://openalex.org/W1857670989","https://openalex.org/W1960351623","https://openalex.org/W1964903392","https://openalex.org/W1965050591","https://openalex.org/W1970222079","https://openalex.org/W1970896571","https://openalex.org/W1973813421","https://openalex.org/W1984018069","https://openalex.org/W1992915004","https://openalex.org/W1993037363","https://openalex.org/W1996722469","https://openalex.org/W1999274925","https://openalex.org/W1999518388","https://openalex.org/W2004486211","https://openalex.org/W2009834470","https://openalex.org/W2011420188","https://openalex.org/W2016452430","https://openalex.org/W2018027744","https://openalex.org/W2028857699","https://openalex.org/W2033610638","https://openalex.org/W2047210789","https://openalex.org/W2061144228","https://openalex.org/W2084243383","https://openalex.org/W2099308902","https://openalex.org/W2103157745","https://openalex.org/W2106728135","https://openalex.org/W2124356165","https://openalex.org/W2126440374","https://openalex.org/W2127870571","https://openalex.org/W2133321281","https://openalex.org/W2142165549","https://openalex.org/W2146842317","https://openalex.org/W2318035687","https://openalex.org/W4242768823","https://openalex.org/W6651186015","https://openalex.org/W6671648748"],"related_works":["https://openalex.org/W2119331473","https://openalex.org/W2326896496","https://openalex.org/W4310777585","https://openalex.org/W4386409537","https://openalex.org/W2064756117","https://openalex.org/W161285251","https://openalex.org/W2220102944","https://openalex.org/W4292553325","https://openalex.org/W2035368461","https://openalex.org/W4210976760"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":6},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":1}],"updated_date":"2026-04-05T17:49:38.594831","created_date":"2025-10-10T00:00:00"}