{"id":"https://openalex.org/W3093295230","doi":"https://doi.org/10.1016/j.biosystems.2020.104278","title":"Contribution of AMPA and NMDA receptors in the spontaneous firing patterns of single neurons in autaptic culture","display_name":"Contribution of AMPA and NMDA receptors in the spontaneous firing patterns of single neurons in autaptic culture","publication_year":2020,"publication_date":"2020-10-16","ids":{"openalex":"https://openalex.org/W3093295230","doi":"https://doi.org/10.1016/j.biosystems.2020.104278","mag":"3093295230","pmid":"https://pubmed.ncbi.nlm.nih.gov/33075473"},"language":"en","primary_location":{"id":"doi:10.1016/j.biosystems.2020.104278","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.biosystems.2020.104278","pdf_url":null,"source":{"id":"https://openalex.org/S99347777","display_name":"Biosystems","issn_l":"0303-2647","issn":["0303-2647","1872-8324"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biosystems","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.biosystems.2020.104278","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089004456","display_name":"Kouhei Hattori","orcid":"https://orcid.org/0000-0002-8156-2536"},"institutions":[{"id":"https://openalex.org/I150744194","display_name":"Waseda University","ror":"https://ror.org/00ntfnx83","country_code":"JP","type":"education","lineage":["https://openalex.org/I150744194"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Kouhei Hattori","raw_affiliation_strings":["Waseda University, Faculty of Science and Engineering, 3-4-1 Okubo, Shinjuku, Tokyo 169-8555, Japan. Electronic address: k_hattori@aoni.waseda.jp","Waseda University, Faculty of Science and Engineering, 3-4-1 Okubo, Shinjuku, Tokyo 169-8555, Japan"],"affiliations":[{"raw_affiliation_string":"Waseda University, Faculty of Science and Engineering, 3-4-1 Okubo, Shinjuku, Tokyo 169-8555, Japan. Electronic address: k_hattori@aoni.waseda.jp","institution_ids":["https://openalex.org/I150744194"]},{"raw_affiliation_string":"Waseda University, Faculty of Science and Engineering, 3-4-1 Okubo, Shinjuku, Tokyo 169-8555, Japan","institution_ids":["https://openalex.org/I150744194"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091523762","display_name":"Takeshi Hayakawa","orcid":"https://orcid.org/0000-0002-8420-3758"},"institutions":[{"id":"https://openalex.org/I201537933","display_name":"Tohoku University","ror":"https://ror.org/01dq60k83","country_code":"JP","type":"education","lineage":["https://openalex.org/I201537933"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takeshi Hayakawa","raw_affiliation_strings":["Tohoku University, Research Institute of Electrical Communication, 2-1-1 Katahira, Aoba, Sendai 980-8577, Japan"],"affiliations":[{"raw_affiliation_string":"Tohoku University, Research Institute of Electrical Communication, 2-1-1 Katahira, Aoba, Sendai 980-8577, Japan","institution_ids":["https://openalex.org/I201537933"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018952575","display_name":"Akira Nakanishi","orcid":null},"institutions":[{"id":"https://openalex.org/I150744194","display_name":"Waseda University","ror":"https://ror.org/00ntfnx83","country_code":"JP","type":"education","lineage":["https://openalex.org/I150744194"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Akira Nakanishi","raw_affiliation_strings":["Waseda University, Faculty of Science and Engineering, 3-4-1 Okubo, Shinjuku, Tokyo 169-8555, Japan"],"affiliations":[{"raw_affiliation_string":"Waseda University, Faculty of Science and Engineering, 3-4-1 Okubo, Shinjuku, Tokyo 169-8555, Japan","institution_ids":["https://openalex.org/I150744194"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013109004","display_name":"Mihoko Ishida","orcid":null},"institutions":[{"id":"https://openalex.org/I150744194","display_name":"Waseda University","ror":"https://ror.org/00ntfnx83","country_code":"JP","type":"education","lineage":["https://openalex.org/I150744194"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Mihoko Ishida","raw_affiliation_strings":["Waseda University, Faculty of Science and Engineering, 3-4-1 Okubo, Shinjuku, Tokyo 169-8555, Japan"],"affiliations":[{"raw_affiliation_string":"Waseda University, Faculty of Science and Engineering, 3-4-1 Okubo, Shinjuku, Tokyo 169-8555, Japan","institution_ids":["https://openalex.org/I150744194"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050554151","display_name":"Hideaki Yamamoto","orcid":"https://orcid.org/0000-0003-3362-5376"},"institutions":[{"id":"https://openalex.org/I201537933","display_name":"Tohoku University","ror":"https://ror.org/01dq60k83","country_code":"JP","type":"education","lineage":["https://openalex.org/I201537933"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hideaki Yamamoto","raw_affiliation_strings":["Tohoku University, Research Institute of Electrical Communication, 2-1-1 Katahira, Aoba, Sendai 980-8577, Japan"],"affiliations":[{"raw_affiliation_string":"Tohoku University, Research Institute of Electrical Communication, 2-1-1 Katahira, Aoba, Sendai 980-8577, Japan","institution_ids":["https://openalex.org/I201537933"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088331142","display_name":"Ayumi Hirano\u2010Iwata","orcid":"https://orcid.org/0000-0002-3043-7698"},"institutions":[{"id":"https://openalex.org/I201537933","display_name":"Tohoku University","ror":"https://ror.org/01dq60k83","country_code":"JP","type":"education","lineage":["https://openalex.org/I201537933"]},{"id":"https://openalex.org/I4210094683","display_name":"Advanced Institute of Materials Science","ror":"https://ror.org/00p5prq49","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210094683"]},{"id":"https://openalex.org/I4387152242","display_name":"Institute for Materials Research, Tohoku University","ror":"https://ror.org/04664mr26","country_code":null,"type":"facility","lineage":["https://openalex.org/I201537933","https://openalex.org/I4387152242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ayumi Hirano-Iwata","raw_affiliation_strings":["Tohoku University, Research Institute of Electrical Communication, 2-1-1 Katahira, Aoba, Sendai 980-8577, Japan; Tohoku University, WPI-Advanced Institute for Materials Research (WPI-AIMR), 2-1-1 Katahira, Aoba, Sendai 980-8577, Japan","Tohoku University, WPI-Advanced Institute for Materials Research (WPI-AIMR), 2-1-1 Katahira, Aoba, Sendai 980-8577, Japan","Tohoku University, Research Institute of Electrical Communication, 2-1-1 Katahira, Aoba, Sendai 980-8577, Japan"],"affiliations":[{"raw_affiliation_string":"Tohoku University, Research Institute of Electrical Communication, 2-1-1 Katahira, Aoba, Sendai 980-8577, Japan; Tohoku University, WPI-Advanced Institute for Materials Research (WPI-AIMR), 2-1-1 Katahira, Aoba, Sendai 980-8577, Japan","institution_ids":["https://openalex.org/I201537933"]},{"raw_affiliation_string":"Tohoku University, WPI-Advanced Institute for Materials Research (WPI-AIMR), 2-1-1 Katahira, Aoba, Sendai 980-8577, Japan","institution_ids":["https://openalex.org/I4210094683","https://openalex.org/I201537933","https://openalex.org/I4387152242"]},{"raw_affiliation_string":"Tohoku University, Research Institute of Electrical Communication, 2-1-1 Katahira, Aoba, Sendai 980-8577, Japan","institution_ids":["https://openalex.org/I201537933"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101770037","display_name":"Takashi Tanii","orcid":"https://orcid.org/0000-0001-8968-2076"},"institutions":[{"id":"https://openalex.org/I150744194","display_name":"Waseda University","ror":"https://ror.org/00ntfnx83","country_code":"JP","type":"education","lineage":["https://openalex.org/I150744194"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takashi Tanii","raw_affiliation_strings":["Waseda University, Faculty of Science and Engineering, 3-4-1 Okubo, Shinjuku, Tokyo 169-8555, Japan"],"affiliations":[{"raw_affiliation_string":"Waseda University, Faculty of Science and Engineering, 3-4-1 Okubo, Shinjuku, Tokyo 169-8555, Japan","institution_ids":["https://openalex.org/I150744194"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5089004456"],"corresponding_institution_ids":["https://openalex.org/I150744194"],"apc_list":{"value":2700,"currency":"USD","value_usd":2700},"apc_paid":{"value":2700,"currency":"USD","value_usd":2700},"fwci":0.1039,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.41616861,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"198","issue":null,"first_page":"104278","last_page":"104278"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11513","display_name":"stochastic dynamics and bifurcation","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/3109","display_name":"Statistical and Nonlinear Physics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ampa-receptor","display_name":"AMPA receptor","score":0.8475215435028076},{"id":"https://openalex.org/keywords/nmda-receptor","display_name":"NMDA receptor","score":0.6966252326965332},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.6605090498924255},{"id":"https://openalex.org/keywords/patch-clamp","display_name":"Patch clamp","score":0.5315518379211426},{"id":"https://openalex.org/keywords/neuron","display_name":"Neuron","score":0.4956759214401245},{"id":"https://openalex.org/keywords/biological-system","display_name":"Biological system","score":0.47920140624046326},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.40247148275375366},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.38376128673553467},{"id":"https://openalex.org/keywords/electrophysiology","display_name":"Electrophysiology","score":0.38268110156059265},{"id":"https://openalex.org/keywords/receptor","display_name":"Receptor","score":0.20386704802513123},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.0701000988483429}],"concepts":[{"id":"https://openalex.org/C160268369","wikidata":"https://www.wikidata.org/wiki/Q295251","display_name":"AMPA receptor","level":4,"score":0.8475215435028076},{"id":"https://openalex.org/C67018056","wikidata":"https://www.wikidata.org/wiki/Q414896","display_name":"NMDA receptor","level":3,"score":0.6966252326965332},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6605090498924255},{"id":"https://openalex.org/C147944092","wikidata":"https://www.wikidata.org/wiki/Q176366","display_name":"Patch clamp","level":3,"score":0.5315518379211426},{"id":"https://openalex.org/C2778794669","wikidata":"https://www.wikidata.org/wiki/Q43054","display_name":"Neuron","level":2,"score":0.4956759214401245},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.47920140624046326},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.40247148275375366},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.38376128673553467},{"id":"https://openalex.org/C185263204","wikidata":"https://www.wikidata.org/wiki/Q1154774","display_name":"Electrophysiology","level":2,"score":0.38268110156059265},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.20386704802513123},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0701000988483429}],"mesh":[{"descriptor_ui":"D000200","descriptor_name":"Action Potentials","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D000200","descriptor_name":"Action Potentials","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D000200","descriptor_name":"Action Potentials","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D000200","descriptor_name":"Action Potentials","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000200","descriptor_name":"Action Potentials","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000200","descriptor_name":"Action Potentials","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008274","descriptor_name":"Magnesium","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D008274","descriptor_name":"Magnesium","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D008274","descriptor_name":"Magnesium","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009435","descriptor_name":"Synaptic Transmission","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009435","descriptor_name":"Synaptic Transmission","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009435","descriptor_name":"Synaptic Transmission","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009435","descriptor_name":"Synaptic Transmission","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009435","descriptor_name":"Synaptic Transmission","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009435","descriptor_name":"Synaptic Transmission","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016194","descriptor_name":"Receptors, N-Methyl-D-Aspartate","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016194","descriptor_name":"Receptors, N-Methyl-D-Aspartate","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016194","descriptor_name":"Receptors, N-Methyl-D-Aspartate","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018091","descriptor_name":"Receptors, AMPA","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018091","descriptor_name":"Receptors, AMPA","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018091","descriptor_name":"Receptors, AMPA","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D059010","descriptor_name":"Single-Cell Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D059010","descriptor_name":"Single-Cell Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D059010","descriptor_name":"Single-Cell Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.biosystems.2020.104278","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.biosystems.2020.104278","pdf_url":null,"source":{"id":"https://openalex.org/S99347777","display_name":"Biosystems","issn_l":"0303-2647","issn":["0303-2647","1872-8324"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biosystems","raw_type":"journal-article"},{"id":"pmid:33075473","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33075473","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bio Systems","raw_type":null}],"best_oa_location":{"id":"doi:10.1016/j.biosystems.2020.104278","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.biosystems.2020.104278","pdf_url":null,"source":{"id":"https://openalex.org/S99347777","display_name":"Biosystems","issn_l":"0303-2647","issn":["0303-2647","1872-8324"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biosystems","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"},{"id":"https://openalex.org/F4320334789","display_name":"Japan Science and Technology Agency","ror":"https://ror.org/00097mb19"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":53,"referenced_works":["https://openalex.org/W149162101","https://openalex.org/W1512746852","https://openalex.org/W1924828367","https://openalex.org/W1930498924","https://openalex.org/W1968901856","https://openalex.org/W1975234774","https://openalex.org/W1983618835","https://openalex.org/W1985940938","https://openalex.org/W1988041026","https://openalex.org/W2013384026","https://openalex.org/W2018991786","https://openalex.org/W2028878964","https://openalex.org/W2031543773","https://openalex.org/W2034951449","https://openalex.org/W2037061813","https://openalex.org/W2038479149","https://openalex.org/W2038879792","https://openalex.org/W2045018745","https://openalex.org/W2047524073","https://openalex.org/W2048810703","https://openalex.org/W2073361892","https://openalex.org/W2076324460","https://openalex.org/W2078029552","https://openalex.org/W2078057675","https://openalex.org/W2084913706","https://openalex.org/W2085857562","https://openalex.org/W2092044902","https://openalex.org/W2118779370","https://openalex.org/W2126857569","https://openalex.org/W2140899588","https://openalex.org/W2146831880","https://openalex.org/W2149645185","https://openalex.org/W2152896566","https://openalex.org/W2193948184","https://openalex.org/W2262647079","https://openalex.org/W2270999310","https://openalex.org/W2319381411","https://openalex.org/W2408998367","https://openalex.org/W2486232056","https://openalex.org/W2509550680","https://openalex.org/W2522357052","https://openalex.org/W2783332744","https://openalex.org/W2790952399","https://openalex.org/W2809466050","https://openalex.org/W2892820676","https://openalex.org/W2898524098","https://openalex.org/W2901218562","https://openalex.org/W2964102936","https://openalex.org/W4406059073","https://openalex.org/W6657420680","https://openalex.org/W6682940159","https://openalex.org/W6714456234","https://openalex.org/W6747687171"],"related_works":["https://openalex.org/W2390095950","https://openalex.org/W3095881549","https://openalex.org/W2418113148","https://openalex.org/W2010421080","https://openalex.org/W4386036099","https://openalex.org/W1602821210","https://openalex.org/W2026638115","https://openalex.org/W324394568","https://openalex.org/W808775712","https://openalex.org/W2354951284"],"abstract_inverted_index":{"Single":[0],"neurons":[1,71,121],"in":[2,51,117,124,139,148],"an":[3,28],"autaptic":[4],"culture":[5],"exhibit":[6],"various":[7,73],"types":[8,81,110],"of":[9,40,43,82,101,111],"firing":[10,14,33,74,84,92,112],"pattern":[11,34],"with":[12,21,35],"different":[13],"durations":[15],"and":[16,58,64,89,132,145],"rhythms.":[17],"However,":[18],"a":[19,31,36,44],"neuron":[20],"autapses":[22,141],"has":[23],"often":[24],"been":[25],"modeled":[26],"as":[27],"oscillator":[29],"providing":[30],"monotonic":[32],"constant":[37],"periodicity":[38],"because":[39],"the":[41,48,66,77,98,118,130],"lack":[42],"mathematical":[45],"model.":[46],"In":[47,76],"work":[49],"described":[50],"this":[52],"study,":[53],"we":[54,136],"use":[55],"computational":[56,78],"simulation":[57],"whole-cell":[59],"patch-clamp":[60],"recording":[61],"to":[62,104],"elucidate":[63],"model":[65],"mechanism":[67],"by":[68,96],"which":[69],"such":[70],"generate":[72],"pattens.":[75],"simulation,":[79],"three":[80,109],"spontaneous":[83],"pattern,":[85],"i.e.,":[86],"short,":[87],"long-lasting,":[88],"periodic":[90],"burst":[91],"patterns":[93,113],"are":[94,114,122],"realized":[95],"changing":[97],"combination":[99],"ratio":[100],"N-methyl-d-aspartate":[102],"(NMDA)":[103],"\u03b1-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate":[105],"(AMPA)":[106],"conductance.":[107],"These":[108],"also":[115],"observed":[116],"experiments":[119],"where":[120],"cultured":[123],"isolation":[125],"on":[126],"micropatterned":[127],"substrates.":[128],"Using":[129],"AMPA":[131],"NMDA":[133],"current":[134],"models,":[135],"discuss":[137],"that,":[138],"principle,":[140],"can":[142],"regulate":[143],"rhythmicity":[144],"information":[146],"selection":[147],"neuronal":[149],"networks.":[150]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2021,"cited_by_count":1}],"updated_date":"2026-03-27T14:29:43.386196","created_date":"2025-10-10T00:00:00"}