{"id":"https://openalex.org/W2804362484","doi":"https://doi.org/10.1016/j.biosystems.2018.05.002","title":"A discriminative test among the different theories proposed to explain the origin of the genetic code: The coevolution theory finds additional support","display_name":"A discriminative test among the different theories proposed to explain the origin of the genetic code: The coevolution theory finds additional support","publication_year":2018,"publication_date":"2018-05-19","ids":{"openalex":"https://openalex.org/W2804362484","doi":"https://doi.org/10.1016/j.biosystems.2018.05.002","mag":"2804362484","pmid":"https://pubmed.ncbi.nlm.nih.gov/29787790"},"language":"en","primary_location":{"id":"doi:10.1016/j.biosystems.2018.05.002","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.biosystems.2018.05.002","pdf_url":null,"source":{"id":"https://openalex.org/S99347777","display_name":"Biosystems","issn_l":"0303-2647","issn":["0303-2647","1872-8324"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biosystems","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5016903088","display_name":"Massimo Di Giulio","orcid":"https://orcid.org/0000-0003-2660-2571"},"institutions":[{"id":"https://openalex.org/I4210108634","display_name":"Institute of Biosciences and Bioresources","ror":"https://ror.org/01gtsa866","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210108634","https://openalex.org/I4210155236"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Massimo Di Giulio","raw_affiliation_strings":["Early Evolution of Life Laboratory, Institute of Biosciences and Bioresources, CNR, Via P. Castellino, 111, 80131 Naples, Italy. Electronic address: massimo.digiulio@ibbr.cnr.it","Early Evolution of Life Laboratory, Institute of Biosciences and Bioresources, CNR, Via P. Castellino, 111, 80131 Naples, Italy"],"affiliations":[{"raw_affiliation_string":"Early Evolution of Life Laboratory, Institute of Biosciences and Bioresources, CNR, Via P. Castellino, 111, 80131 Naples, Italy. Electronic address: massimo.digiulio@ibbr.cnr.it","institution_ids":[]},{"raw_affiliation_string":"Early Evolution of Life Laboratory, Institute of Biosciences and Bioresources, CNR, Via P. Castellino, 111, 80131 Naples, Italy","institution_ids":["https://openalex.org/I4210108634"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5016903088"],"corresponding_institution_ids":["https://openalex.org/I4210108634"],"apc_list":{"value":2700,"currency":"USD","value_usd":2700},"apc_paid":null,"fwci":1.9303,"has_fulltext":false,"cited_by_count":28,"citation_normalized_percentile":{"value":0.86579804,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"169-170","issue":null,"first_page":"1","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9947999715805054,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9947999715805054,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11764","display_name":"Evolution and Genetic Dynamics","score":0.9927999973297119,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12946","display_name":"Fractal and DNA sequence analysis","score":0.9713000059127808,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/coevolution","display_name":"Coevolution","score":0.8275272846221924},{"id":"https://openalex.org/keywords/discriminative-model","display_name":"Discriminative model","score":0.7736105918884277},{"id":"https://openalex.org/keywords/genetic-code","display_name":"Genetic code","score":0.6430648565292358},{"id":"https://openalex.org/keywords/code","display_name":"Code (set theory)","score":0.6326186656951904},{"id":"https://openalex.org/keywords/expression","display_name":"Expression (computer science)","score":0.4736539125442505},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.40169447660446167},{"id":"https://openalex.org/keywords/evolutionary-biology","display_name":"Evolutionary biology","score":0.281941294670105},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.28138673305511475},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2715691030025482},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.20302337408065796},{"id":"https://openalex.org/keywords/dna","display_name":"DNA","score":0.09135204553604126},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.06578683853149414}],"concepts":[{"id":"https://openalex.org/C33009525","wikidata":"https://www.wikidata.org/wiki/Q208841","display_name":"Coevolution","level":2,"score":0.8275272846221924},{"id":"https://openalex.org/C97931131","wikidata":"https://www.wikidata.org/wiki/Q5282087","display_name":"Discriminative model","level":2,"score":0.7736105918884277},{"id":"https://openalex.org/C10853874","wikidata":"https://www.wikidata.org/wiki/Q180618","display_name":"Genetic code","level":3,"score":0.6430648565292358},{"id":"https://openalex.org/C2776760102","wikidata":"https://www.wikidata.org/wiki/Q5139990","display_name":"Code (set theory)","level":3,"score":0.6326186656951904},{"id":"https://openalex.org/C90559484","wikidata":"https://www.wikidata.org/wiki/Q778379","display_name":"Expression (computer science)","level":2,"score":0.4736539125442505},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.40169447660446167},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.281941294670105},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.28138673305511475},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2715691030025482},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.20302337408065796},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.09135204553604126},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.06578683853149414},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000596","descriptor_name":"Amino Acids","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000596","descriptor_name":"Amino Acids","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000596","descriptor_name":"Amino Acids","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005815","descriptor_name":"Genetic Code","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005815","descriptor_name":"Genetic Code","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005815","descriptor_name":"Genetic Code","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011336","descriptor_name":"Probability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011336","descriptor_name":"Probability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011336","descriptor_name":"Probability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019143","descriptor_name":"Evolution, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019143","descriptor_name":"Evolution, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019143","descriptor_name":"Evolution, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.biosystems.2018.05.002","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.biosystems.2018.05.002","pdf_url":null,"source":{"id":"https://openalex.org/S99347777","display_name":"Biosystems","issn_l":"0303-2647","issn":["0303-2647","1872-8324"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biosystems","raw_type":"journal-article"},{"id":"pmid:29787790","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29787790","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bio Systems","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Reduced inequalities","score":0.7799999713897705,"id":"https://metadata.un.org/sdg/10"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":59,"referenced_works":["https://openalex.org/W27875803","https://openalex.org/W124945654","https://openalex.org/W797482215","https://openalex.org/W1514819411","https://openalex.org/W1569940736","https://openalex.org/W1631484173","https://openalex.org/W1924311576","https://openalex.org/W1973295691","https://openalex.org/W1977390115","https://openalex.org/W1978595049","https://openalex.org/W1979816467","https://openalex.org/W1982081746","https://openalex.org/W1987724079","https://openalex.org/W1987753787","https://openalex.org/W1992787480","https://openalex.org/W1998652556","https://openalex.org/W2004099320","https://openalex.org/W2009542365","https://openalex.org/W2018892842","https://openalex.org/W2020571154","https://openalex.org/W2020772746","https://openalex.org/W2021894945","https://openalex.org/W2023236613","https://openalex.org/W2027298209","https://openalex.org/W2028138260","https://openalex.org/W2044214664","https://openalex.org/W2045400243","https://openalex.org/W2047119430","https://openalex.org/W2050083284","https://openalex.org/W2054592804","https://openalex.org/W2061956168","https://openalex.org/W2071636507","https://openalex.org/W2080018045","https://openalex.org/W2082190159","https://openalex.org/W2082967593","https://openalex.org/W2087705045","https://openalex.org/W2098015235","https://openalex.org/W2100681850","https://openalex.org/W2123541473","https://openalex.org/W2134889261","https://openalex.org/W2136281516","https://openalex.org/W2138220095","https://openalex.org/W2140139413","https://openalex.org/W2141110609","https://openalex.org/W2163430391","https://openalex.org/W2207367044","https://openalex.org/W2240687241","https://openalex.org/W2314833535","https://openalex.org/W2329044272","https://openalex.org/W2330555996","https://openalex.org/W2418065224","https://openalex.org/W2531179033","https://openalex.org/W2553641689","https://openalex.org/W2607091304","https://openalex.org/W2745246328","https://openalex.org/W4231404852","https://openalex.org/W4248779454","https://openalex.org/W4299735549","https://openalex.org/W6601097472"],"related_works":["https://openalex.org/W2138220095","https://openalex.org/W2745246328","https://openalex.org/W2207367044","https://openalex.org/W2116100216","https://openalex.org/W2752271443","https://openalex.org/W2068095283","https://openalex.org/W2134889261","https://openalex.org/W124945654","https://openalex.org/W2054508923","https://openalex.org/W2003262823"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":10},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":3}],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2025-10-10T00:00:00"}