{"id":"https://openalex.org/W1983562846","doi":"https://doi.org/10.1007/s10878-005-1859-8","title":"Computational Comparison Studies of Quadratic Assignment Like Formulations for the In Silico Sequence Selection Problem in De Novo Protein Design","display_name":"Computational Comparison Studies of Quadratic Assignment Like Formulations for the In Silico Sequence Selection Problem in De Novo Protein Design","publication_year":2005,"publication_date":"2005-08-01","ids":{"openalex":"https://openalex.org/W1983562846","doi":"https://doi.org/10.1007/s10878-005-1859-8","mag":"1983562846"},"language":"en","primary_location":{"id":"doi:10.1007/s10878-005-1859-8","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10878-005-1859-8","pdf_url":null,"source":{"id":"https://openalex.org/S107925523","display_name":"Journal of Combinatorial Optimization","issn_l":"1382-6905","issn":["1382-6905","1573-2886"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Combinatorial Optimization","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109849955","display_name":"Ho Ki Fung","orcid":"https://orcid.org/0000-0002-0838-530X"},"institutions":[{"id":"https://openalex.org/I20089843","display_name":"Princeton University","ror":"https://ror.org/00hx57361","country_code":"US","type":"education","lineage":["https://openalex.org/I20089843"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"H. K. Fung","raw_affiliation_strings":["Department of Chemical Engineering, Princeton University, Princeton, NJ, 08544-5263","Department of Chemical Engineering, Princeton University, Princeton"],"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, Princeton University, Princeton, NJ, 08544-5263","institution_ids":["https://openalex.org/I20089843"]},{"raw_affiliation_string":"Department of Chemical Engineering, Princeton University, Princeton","institution_ids":["https://openalex.org/I20089843"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082369624","display_name":"Satish Rao","orcid":"https://orcid.org/0000-0002-7353-333X"},"institutions":[{"id":"https://openalex.org/I20089843","display_name":"Princeton University","ror":"https://ror.org/00hx57361","country_code":"US","type":"education","lineage":["https://openalex.org/I20089843"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S. Rao","raw_affiliation_strings":["Department of Chemical Engineering, Princeton University, Princeton, NJ, 08544-5263","Department of Chemical Engineering, Princeton University, Princeton"],"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, Princeton University, Princeton, NJ, 08544-5263","institution_ids":["https://openalex.org/I20089843"]},{"raw_affiliation_string":"Department of Chemical Engineering, Princeton University, Princeton","institution_ids":["https://openalex.org/I20089843"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050187529","display_name":"Christodoulos A. Floudas","orcid":null},"institutions":[{"id":"https://openalex.org/I20089843","display_name":"Princeton University","ror":"https://ror.org/00hx57361","country_code":"US","type":"education","lineage":["https://openalex.org/I20089843"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C. A. Floudas","raw_affiliation_strings":["Department of Chemical Engineering, Princeton University, Princeton, NJ, 08544-5263","Department of Chemical Engineering, Princeton University, Princeton"],"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, Princeton University, Princeton, NJ, 08544-5263","institution_ids":["https://openalex.org/I20089843"]},{"raw_affiliation_string":"Department of Chemical Engineering, Princeton University, Princeton","institution_ids":["https://openalex.org/I20089843"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057562290","display_name":"Oleg A. Prokopyev","orcid":"https://orcid.org/0000-0003-2888-8630"},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"O. Prokopyev","raw_affiliation_strings":["Department of Industrial and Systems Engineering, University of Florida, Gainesville, FL, 32611-6595","Department of Industrial and Systems Engineering, University of Florida, Gainesville"],"affiliations":[{"raw_affiliation_string":"Department of Industrial and Systems Engineering, University of Florida, Gainesville, FL, 32611-6595","institution_ids":["https://openalex.org/I33213144"]},{"raw_affiliation_string":"Department of Industrial and Systems Engineering, University of Florida, Gainesville","institution_ids":["https://openalex.org/I33213144"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063808461","display_name":"P\u00e3nos M. Pardalos","orcid":"https://orcid.org/0000-0003-2824-101X"},"institutions":[{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"P. M. Pardalos","raw_affiliation_strings":["Department of Industrial and Systems Engineering, University of Florida, Gainesville, FL, 32611-6595","Department of Industrial and Systems Engineering, University of Florida, Gainesville"],"affiliations":[{"raw_affiliation_string":"Department of Industrial and Systems Engineering, University of Florida, Gainesville, FL, 32611-6595","institution_ids":["https://openalex.org/I33213144"]},{"raw_affiliation_string":"Department of Industrial and Systems Engineering, University of Florida, Gainesville","institution_ids":["https://openalex.org/I33213144"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5036114620","display_name":"Franz Rendl","orcid":"https://orcid.org/0000-0003-1578-9414"},"institutions":[{"id":"https://openalex.org/I4210166741","display_name":"University of Klagenfurt","ror":"https://ror.org/05q9m0937","country_code":"AT","type":"education","lineage":["https://openalex.org/I4210166741"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"F. Rendl","raw_affiliation_strings":["Institut f\u00fcr Mathematik, Universit\u00e4t Klagenfurt, A-9020, Klagenfurt, Austria","Institut f\u00fcr Mathematik, Universit\u00c4t Klagenfurt, Klagenfurt, Austria"],"affiliations":[{"raw_affiliation_string":"Institut f\u00fcr Mathematik, Universit\u00e4t Klagenfurt, A-9020, Klagenfurt, Austria","institution_ids":["https://openalex.org/I4210166741"]},{"raw_affiliation_string":"Institut f\u00fcr Mathematik, Universit\u00c4t Klagenfurt, Klagenfurt, Austria","institution_ids":["https://openalex.org/I4210166741"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5109849955"],"corresponding_institution_ids":["https://openalex.org/I20089843"],"apc_list":{"value":2390,"currency":"EUR","value_usd":2990},"apc_paid":null,"fwci":1.3923,"has_fulltext":false,"cited_by_count":29,"citation_normalized_percentile":{"value":0.78922569,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"10","issue":"1","first_page":"41","last_page":"60"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.998199999332428,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.998199999332428,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9958000183105469,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12576","display_name":"vaccines and immunoinformatics approaches","score":0.9948999881744385,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sequence","display_name":"Sequence (biology)","score":0.7140845060348511},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.6051251888275146},{"id":"https://openalex.org/keywords/selection","display_name":"Selection (genetic algorithm)","score":0.5100613236427307},{"id":"https://openalex.org/keywords/linearization","display_name":"Linearization","score":0.4962380528450012},{"id":"https://openalex.org/keywords/binary-number","display_name":"Binary number","score":0.4847559630870819},{"id":"https://openalex.org/keywords/in-silico","display_name":"In silico","score":0.48003971576690674},{"id":"https://openalex.org/keywords/theory-of-computation","display_name":"Theory of computation","score":0.47728005051612854},{"id":"https://openalex.org/keywords/mathematical-optimization","display_name":"Mathematical optimization","score":0.47427353262901306},{"id":"https://openalex.org/keywords/preprocessor","display_name":"Preprocessor","score":0.46820715069770813},{"id":"https://openalex.org/keywords/combinatorics","display_name":"Combinatorics","score":0.461262047290802},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.45328572392463684},{"id":"https://openalex.org/keywords/type","display_name":"Type (biology)","score":0.4441889524459839},{"id":"https://openalex.org/keywords/quadratic-equation","display_name":"Quadratic equation","score":0.43507978320121765},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3246547281742096},{"id":"https://openalex.org/keywords/arithmetic","display_name":"Arithmetic","score":0.08968397974967957}],"concepts":[{"id":"https://openalex.org/C2778112365","wikidata":"https://www.wikidata.org/wiki/Q3511065","display_name":"Sequence (biology)","level":2,"score":0.7140845060348511},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.6051251888275146},{"id":"https://openalex.org/C81917197","wikidata":"https://www.wikidata.org/wiki/Q628760","display_name":"Selection (genetic algorithm)","level":2,"score":0.5100613236427307},{"id":"https://openalex.org/C11210021","wikidata":"https://www.wikidata.org/wiki/Q1520713","display_name":"Linearization","level":3,"score":0.4962380528450012},{"id":"https://openalex.org/C48372109","wikidata":"https://www.wikidata.org/wiki/Q3913","display_name":"Binary number","level":2,"score":0.4847559630870819},{"id":"https://openalex.org/C2775905019","wikidata":"https://www.wikidata.org/wiki/Q192572","display_name":"In silico","level":3,"score":0.48003971576690674},{"id":"https://openalex.org/C24858836","wikidata":"https://www.wikidata.org/wiki/Q844718","display_name":"Theory of computation","level":2,"score":0.47728005051612854},{"id":"https://openalex.org/C126255220","wikidata":"https://www.wikidata.org/wiki/Q141495","display_name":"Mathematical optimization","level":1,"score":0.47427353262901306},{"id":"https://openalex.org/C34736171","wikidata":"https://www.wikidata.org/wiki/Q918333","display_name":"Preprocessor","level":2,"score":0.46820715069770813},{"id":"https://openalex.org/C114614502","wikidata":"https://www.wikidata.org/wiki/Q76592","display_name":"Combinatorics","level":1,"score":0.461262047290802},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.45328572392463684},{"id":"https://openalex.org/C2777299769","wikidata":"https://www.wikidata.org/wiki/Q3707858","display_name":"Type (biology)","level":2,"score":0.4441889524459839},{"id":"https://openalex.org/C129844170","wikidata":"https://www.wikidata.org/wiki/Q41299","display_name":"Quadratic equation","level":2,"score":0.43507978320121765},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3246547281742096},{"id":"https://openalex.org/C94375191","wikidata":"https://www.wikidata.org/wiki/Q11205","display_name":"Arithmetic","level":1,"score":0.08968397974967957},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C158622935","wikidata":"https://www.wikidata.org/wiki/Q660848","display_name":"Nonlinear system","level":2,"score":0.0},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1007/s10878-005-1859-8","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10878-005-1859-8","pdf_url":null,"source":{"id":"https://openalex.org/S107925523","display_name":"Journal of Combinatorial Optimization","issn_l":"1382-6905","issn":["1382-6905","1573-2886"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Combinatorial Optimization","raw_type":"journal-article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.517.5123","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.517.5123","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://titan.princeton.edu/papers/hoki/213.pdf","raw_type":"text"},{"id":"pmh:oai:RePEc:spr:jcomop:v:10:y:2005:i:1:d:10.1007_s10878-005-1859-8","is_oa":false,"landing_page_url":"http://link.springer.com/10.1007/s10878-005-1859-8","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320306080","display_name":"Foundation for the National Institutes of Health","ror":"https://ror.org/00k86s890"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":38,"referenced_works":["https://openalex.org/W200606222","https://openalex.org/W402691944","https://openalex.org/W1490451576","https://openalex.org/W1509956720","https://openalex.org/W1546461095","https://openalex.org/W1550727253","https://openalex.org/W1571070457","https://openalex.org/W1590094999","https://openalex.org/W1906070812","https://openalex.org/W1966523142","https://openalex.org/W1971496656","https://openalex.org/W1971891360","https://openalex.org/W1975313783","https://openalex.org/W1981009968","https://openalex.org/W1983102499","https://openalex.org/W1984425167","https://openalex.org/W1996576490","https://openalex.org/W1997436357","https://openalex.org/W2005088509","https://openalex.org/W2005568087","https://openalex.org/W2013245073","https://openalex.org/W2016038837","https://openalex.org/W2017994171","https://openalex.org/W2034271244","https://openalex.org/W2036287410","https://openalex.org/W2041818766","https://openalex.org/W2075740111","https://openalex.org/W2082221689","https://openalex.org/W2102328679","https://openalex.org/W2106775540","https://openalex.org/W2135580377","https://openalex.org/W2140248032","https://openalex.org/W2146760785","https://openalex.org/W2148480106","https://openalex.org/W2162215949","https://openalex.org/W2894871027","https://openalex.org/W3105592538","https://openalex.org/W4292175028"],"related_works":["https://openalex.org/W2912862995","https://openalex.org/W3129816939","https://openalex.org/W2101501829","https://openalex.org/W2985427592","https://openalex.org/W2003194288","https://openalex.org/W2060263731","https://openalex.org/W391093122","https://openalex.org/W4361305867","https://openalex.org/W1521239975","https://openalex.org/W2113159581"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2026-04-04T16:13:02.066488","created_date":"2025-10-10T00:00:00"}