{"id":"https://openalex.org/W2524621281","doi":"https://doi.org/10.1007/978-3-319-46726-9_40","title":"Improved Diagnosis of Systemic Sclerosis Using Nailfold Capillary Flow","display_name":"Improved Diagnosis of Systemic Sclerosis Using Nailfold Capillary Flow","publication_year":2016,"publication_date":"2016-01-01","ids":{"openalex":"https://openalex.org/W2524621281","doi":"https://doi.org/10.1007/978-3-319-46726-9_40","mag":"2524621281"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-319-46726-9_40","is_oa":true,"landing_page_url":"https://doi.org/10.1007/978-3-319-46726-9_40","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1007/978-3-319-46726-9_40","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027130627","display_name":"Michael Berks","orcid":"https://orcid.org/0000-0003-4727-2006"},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Michael Berks","raw_affiliation_strings":["University of Manchester, Manchester, UK"],"affiliations":[{"raw_affiliation_string":"University of Manchester, Manchester, UK","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024071118","display_name":"Graham Dinsdale","orcid":"https://orcid.org/0000-0001-6245-2721"},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Graham Dinsdale","raw_affiliation_strings":["University of Manchester, Manchester, UK"],"affiliations":[{"raw_affiliation_string":"University of Manchester, Manchester, UK","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045200423","display_name":"Andrea Murray","orcid":"https://orcid.org/0000-0001-9244-2882"},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Andrea Murray","raw_affiliation_strings":["University of Manchester, Manchester, UK"],"affiliations":[{"raw_affiliation_string":"University of Manchester, Manchester, UK","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060867164","display_name":"Tonia Moore","orcid":"https://orcid.org/0000-0002-8353-976X"},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Tonia Moore","raw_affiliation_strings":["University of Manchester, Manchester, UK"],"affiliations":[{"raw_affiliation_string":"University of Manchester, Manchester, UK","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056447660","display_name":"Ariane L. Herrick","orcid":"https://orcid.org/0000-0003-4941-7926"},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ariane Herrick","raw_affiliation_strings":["University of Manchester, Manchester, UK"],"affiliations":[{"raw_affiliation_string":"University of Manchester, Manchester, UK","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5067224766","display_name":"Chris Taylor","orcid":"https://orcid.org/0000-0001-7867-9533"},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Chris Taylor","raw_affiliation_strings":["University of Manchester, Manchester, UK"],"affiliations":[{"raw_affiliation_string":"University of Manchester, Manchester, UK","institution_ids":["https://openalex.org/I28407311"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5027130627"],"corresponding_institution_ids":["https://openalex.org/I28407311"],"apc_list":{"value":5000,"currency":"EUR","value_usd":5392},"apc_paid":{"value":5000,"currency":"EUR","value_usd":5392},"fwci":7.3387,"has_fulltext":true,"cited_by_count":6,"citation_normalized_percentile":{"value":0.97493404,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":95},"biblio":{"volume":null,"issue":null,"first_page":"344","last_page":"352"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11330","display_name":"Systemic Sclerosis and Related Diseases","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11330","display_name":"Systemic Sclerosis and Related Diseases","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11172","display_name":"Dermatologic Treatments and Research","score":0.9968000054359436,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11469","display_name":"Lymphatic System and Diseases","score":0.9940000176429749,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/magnification","display_name":"Magnification","score":0.7703827619552612},{"id":"https://openalex.org/keywords/capillary-action","display_name":"Capillary action","score":0.6871789693832397},{"id":"https://openalex.org/keywords/blood-flow","display_name":"Blood flow","score":0.521024227142334},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4829675257205963},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.3547414541244507},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.3360729217529297},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.24063029885292053},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.23462390899658203},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.15350541472434998}],"concepts":[{"id":"https://openalex.org/C4144372","wikidata":"https://www.wikidata.org/wiki/Q675287","display_name":"Magnification","level":2,"score":0.7703827619552612},{"id":"https://openalex.org/C196806460","wikidata":"https://www.wikidata.org/wiki/Q188603","display_name":"Capillary action","level":2,"score":0.6871789693832397},{"id":"https://openalex.org/C158846371","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Blood flow","level":2,"score":0.521024227142334},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4829675257205963},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3547414541244507},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3360729217529297},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.24063029885292053},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.23462390899658203},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.15350541472434998},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1007/978-3-319-46726-9_40","is_oa":true,"landing_page_url":"https://doi.org/10.1007/978-3-319-46726-9_40","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},{"id":"pmh:oai:pure.atira.dk:openaire_cris_publications/082d41a7-da9c-4151-b670-7fd7b09f3d25","is_oa":true,"landing_page_url":"https://research.manchester.ac.uk/en/publications/082d41a7-da9c-4151-b670-7fd7b09f3d25","pdf_url":null,"source":{"id":"https://openalex.org/S4306400662","display_name":"Research Explorer (The University of Manchester)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I28407311","host_organization_name":"University of Manchester","host_organization_lineage":["https://openalex.org/I28407311"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Berks, M, Dinsdale, G, Murray, A, Moore, T, Herrick, A & Taylor, C 2016, Improved Diagnosis of Systemic Sclerosis Using Nailfold Capillary Flow. in S Ourselin, L Joskowicz, M R Sabuncu, G Unal & W Wells (eds), Medical image computing and computer-assisted intervention -- MICCAI 2016 : 19th International Conference, Athens, Greece, October 17-21, 2016, Proceedings.. vol. 3, Lecture Notes in Computer Science, vol. 9902, Springer Nature, Cham, pp. 344-352. https://doi.org/10.1007/978-3-319-46726-9_40","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:pure.atira.dk:publications/082d41a7-da9c-4151-b670-7fd7b09f3d25","is_oa":true,"landing_page_url":"https://www.research.manchester.ac.uk/portal/en/publications/improved-diagnosis-of-systemic-sclerosis-using-nailfold-capillary-flow(082d41a7-da9c-4151-b670-7fd7b09f3d25).html","pdf_url":"https://pure.manchester.ac.uk/ws/files/47002344/paper1049.pdf","source":{"id":"https://openalex.org/S4306400662","display_name":"Research Explorer (The University of Manchester)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I28407311","host_organization_name":"University of Manchester","host_organization_lineage":["https://openalex.org/I28407311"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Berks, M, Dinsdale, G, Murray, A, Moore, T, Herrick, A & Taylor, C 2016, Improved Diagnosis of Systemic Sclerosis Using Nailfold Capillary Flow. in S Ourselin, L Joskowicz, M R Sabuncu, G Unal & W Wells (eds), Medical image computing and computer-assisted intervention -- MICCAI 2016 : 19th International Conference, Athens, Greece, October 17-21, 2016, Proceedings.. vol. 3, Lecture Notes in Computer Science, vol. 9902, Springer Nature, Cham, pp. 344-352. https://doi.org/10.1007/978-3-319-46726-9_40","raw_type":"info:eu-repo/semantics/publishedVersion"}],"best_oa_location":{"id":"doi:10.1007/978-3-319-46726-9_40","is_oa":true,"landing_page_url":"https://doi.org/10.1007/978-3-319-46726-9_40","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},"sustainable_development_goals":[{"score":0.6600000262260437,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W41033710","https://openalex.org/W1533198840","https://openalex.org/W1578285471","https://openalex.org/W1867429401","https://openalex.org/W1968018468","https://openalex.org/W1982630620","https://openalex.org/W1984263987","https://openalex.org/W1997716961","https://openalex.org/W2113689749","https://openalex.org/W2751023760","https://openalex.org/W4238566795","https://openalex.org/W4249633324"],"related_works":["https://openalex.org/W2748952813","https://openalex.org/W3031052312","https://openalex.org/W4389568370","https://openalex.org/W3032375762","https://openalex.org/W1995515455","https://openalex.org/W2080531066","https://openalex.org/W2586801360","https://openalex.org/W3108674512","https://openalex.org/W1506200166","https://openalex.org/W1489783725"],"abstract_inverted_index":{"Nailfold":[0],"capillaroscopy":[1],"(NC)":[2],"allows":[3],"non-invasive":[4],"imaging":[5,24],"of":[6,25,40,52,84],"systemic":[7],"sclerosis":[8],"(SSc)":[9],"related":[10],"microvascular":[11],"disease.":[12],"We":[13,47],"have":[14],"developed":[15],"a":[16,53,81],"state-of-the-art":[17],"NC":[18],"system":[19],"that":[20,80],"enables":[21],"fast,":[22],"panoramic":[23],"the":[26,49,75],"whole":[27],"nailfold":[28],"at":[29],"high-magnification,":[30],"and":[31,43,67,78],"incorporates":[32],"novel":[33],"software":[34],"to":[35,105],"make":[36],"fully":[37],"automated":[38],"estimates":[39],"capillary":[41,85,95,106],"structure":[42,107],"blood":[44],"flow":[45,96,101],"velocity.":[46],"present":[48],"first":[50],"results":[51],"study":[54],"in":[55],"which":[56],"50":[57,68],"patients":[58],"with":[59,62],"SSc,":[60],"12":[61],"primary":[63],"Raynauds":[64],"phenomenon":[65],"(PRP)":[66],"healthy":[69],"controls":[70],"(HC)":[71],"were":[72],"imaged":[73],"using":[74],"new":[76],"system,":[77],"show":[79],"combined":[82],"model":[83,98],"measurements":[86],"strongly":[87],"separates":[88],"SSc":[89],"from":[90],"HC/PRP":[91],"(ROC":[92],"$$A_z$$=0.93).":[93],"Including":[94],"improves":[97],"performance,":[99],"suggesting":[100],"provides":[102],"complementary":[103],"information":[104],"for":[108],"diagnosing":[109],"SSc.":[110]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2026-04-05T17:49:38.594831","created_date":"2025-10-10T00:00:00"}