{"id":"https://openalex.org/W4412546057","doi":"https://doi.org/10.1007/s40747-025-02025-1","title":"Local\u2013global feature fusion for enhanced Alzheimer\u2019s detection: a multi-scale attention-driven MRI classification model","display_name":"Local\u2013global feature fusion for enhanced Alzheimer\u2019s detection: a multi-scale attention-driven MRI classification model","publication_year":2025,"publication_date":"2025-07-22","ids":{"openalex":"https://openalex.org/W4412546057","doi":"https://doi.org/10.1007/s40747-025-02025-1"},"language":"en","primary_location":{"id":"doi:10.1007/s40747-025-02025-1","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s40747-025-02025-1","pdf_url":"https://link.springer.com/content/pdf/10.1007/s40747-025-02025-1.pdf","source":{"id":"https://openalex.org/S3035462843","display_name":"Complex & Intelligent Systems","issn_l":"2198-6053","issn":["2198-6053","2199-4536"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Complex & Intelligent Systems","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://link.springer.com/content/pdf/10.1007/s40747-025-02025-1.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020994807","display_name":"Kerang Cao","orcid":"https://orcid.org/0000-0002-4053-7166"},"institutions":[{"id":"https://openalex.org/I157507598","display_name":"Shenyang University of Technology","ror":"https://ror.org/00d7f8730","country_code":"CN","type":"education","lineage":["https://openalex.org/I157507598"]},{"id":"https://openalex.org/I48780066","display_name":"Shenyang University of Chemical Technology","ror":"https://ror.org/03dbpdh75","country_code":"CN","type":"education","lineage":["https://openalex.org/I48780066"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kerang Cao","raw_affiliation_strings":["College of Computer Science and Technology, Shenyang University of Chemical Technology, Shenyang, Liaoning Province, China","Key Laboratory of Intelligent Technology of Chemical Process Industry in Liaoning Province, Shenyang, Liaoning Province, China"],"affiliations":[{"raw_affiliation_string":"College of Computer Science and Technology, Shenyang University of Chemical Technology, Shenyang, Liaoning Province, China","institution_ids":["https://openalex.org/I157507598","https://openalex.org/I48780066"]},{"raw_affiliation_string":"Key Laboratory of Intelligent Technology of Chemical Process Industry in Liaoning Province, Shenyang, Liaoning Province, China","institution_ids":["https://openalex.org/I48780066"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Zhongqing Lu","orcid":"https://orcid.org/0009-0007-0659-1066"},"institutions":[{"id":"https://openalex.org/I157507598","display_name":"Shenyang University of Technology","ror":"https://ror.org/00d7f8730","country_code":"CN","type":"education","lineage":["https://openalex.org/I157507598"]},{"id":"https://openalex.org/I48780066","display_name":"Shenyang University of Chemical Technology","ror":"https://ror.org/03dbpdh75","country_code":"CN","type":"education","lineage":["https://openalex.org/I48780066"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhongqing Lu","raw_affiliation_strings":["College of Computer Science and Technology, Shenyang University of Chemical Technology, Shenyang, Liaoning Province, China","Key Laboratory of Intelligent Technology of Chemical Process Industry in Liaoning Province, Shenyang, Liaoning Province, China"],"affiliations":[{"raw_affiliation_string":"College of Computer Science and Technology, Shenyang University of Chemical Technology, Shenyang, Liaoning Province, China","institution_ids":["https://openalex.org/I157507598","https://openalex.org/I48780066"]},{"raw_affiliation_string":"Key Laboratory of Intelligent Technology of Chemical Process Industry in Liaoning Province, Shenyang, Liaoning Province, China","institution_ids":["https://openalex.org/I48780066"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005848045","display_name":"Kaidi Zhang","orcid":"https://orcid.org/0000-0002-1453-0681"},"institutions":[{"id":"https://openalex.org/I157507598","display_name":"Shenyang University of Technology","ror":"https://ror.org/00d7f8730","country_code":"CN","type":"education","lineage":["https://openalex.org/I157507598"]},{"id":"https://openalex.org/I48780066","display_name":"Shenyang University of Chemical Technology","ror":"https://ror.org/03dbpdh75","country_code":"CN","type":"education","lineage":["https://openalex.org/I48780066"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kaidi Zhang","raw_affiliation_strings":["College of Computer Science and Technology, Shenyang University of Chemical Technology, Shenyang, Liaoning Province, China","Key Laboratory of Intelligent Technology of Chemical Process Industry in Liaoning Province, Shenyang, Liaoning Province, China"],"affiliations":[{"raw_affiliation_string":"College of Computer Science and Technology, Shenyang University of Chemical Technology, Shenyang, Liaoning Province, China","institution_ids":["https://openalex.org/I157507598","https://openalex.org/I48780066"]},{"raw_affiliation_string":"Key Laboratory of Intelligent Technology of Chemical Process Industry in Liaoning Province, Shenyang, Liaoning Province, China","institution_ids":["https://openalex.org/I48780066"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111316093","display_name":"Yu Liu","orcid":null},"institutions":[{"id":"https://openalex.org/I91656880","display_name":"China Medical University","ror":"https://ror.org/032d4f246","country_code":"CN","type":"education","lineage":["https://openalex.org/I91656880"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yu Liu","raw_affiliation_strings":["Department of Neurosurgery, Shengjing Hospital of China Medical University, Shenyang, China"],"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Shengjing Hospital of China Medical University, Shenyang, China","institution_ids":["https://openalex.org/I91656880"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101548105","display_name":"Ye Ma","orcid":"https://orcid.org/0000-0002-2086-5648"},"institutions":[{"id":"https://openalex.org/I27357992","display_name":"Dalian University of Technology","ror":"https://ror.org/023hj5876","country_code":"CN","type":"education","lineage":["https://openalex.org/I27357992"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ye Ma","raw_affiliation_strings":["School of Computer Science and Technology, Dalian University of Technology, Dalian, Liaoning Province, China"],"affiliations":[{"raw_affiliation_string":"School of Computer Science and Technology, Dalian University of Technology, Dalian, Liaoning Province, China","institution_ids":["https://openalex.org/I27357992"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031035207","display_name":"Jun Wang","orcid":"https://orcid.org/0009-0009-5629-5016"},"institutions":[{"id":"https://openalex.org/I157507598","display_name":"Shenyang University of Technology","ror":"https://ror.org/00d7f8730","country_code":"CN","type":"education","lineage":["https://openalex.org/I157507598"]},{"id":"https://openalex.org/I48780066","display_name":"Shenyang University of Chemical Technology","ror":"https://ror.org/03dbpdh75","country_code":"CN","type":"education","lineage":["https://openalex.org/I48780066"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jun Wang","raw_affiliation_strings":["College of Computer Science and Technology, Shenyang University of Chemical Technology, Shenyang, Liaoning Province, China","Key Laboratory of Intelligent Technology of Chemical Process Industry in Liaoning Province, Shenyang, Liaoning Province, China"],"affiliations":[{"raw_affiliation_string":"College of Computer Science and Technology, Shenyang University of Chemical Technology, Shenyang, Liaoning Province, China","institution_ids":["https://openalex.org/I157507598","https://openalex.org/I48780066"]},{"raw_affiliation_string":"Key Laboratory of Intelligent Technology of Chemical Process Industry in Liaoning Province, Shenyang, Liaoning Province, China","institution_ids":["https://openalex.org/I48780066"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033114960","display_name":"Hoe-Kyung Jung","orcid":"https://orcid.org/0000-0002-7607-1126"},"institutions":[{"id":"https://openalex.org/I110118728","display_name":"Pai Chai University","ror":"https://ror.org/05drcjw53","country_code":"KR","type":"education","lineage":["https://openalex.org/I110118728"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Hoekyung Jung","raw_affiliation_strings":["Computer Engineering Department, Paichai University, Daejeon, Republic of Korea"],"affiliations":[{"raw_affiliation_string":"Computer Engineering Department, Paichai University, Daejeon, Republic of Korea","institution_ids":["https://openalex.org/I110118728"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5033114960"],"corresponding_institution_ids":["https://openalex.org/I110118728"],"apc_list":{"value":1320,"currency":"GBP","value_usd":1619},"apc_paid":{"value":1320,"currency":"GBP","value_usd":1619},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.21814407,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"11","issue":"9","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12702","display_name":"Brain Tumor Detection and Classification","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12702","display_name":"Brain Tumor Detection and Classification","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.9986000061035156,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11659","display_name":"Advanced Image Fusion Techniques","score":0.9950000047683716,"subfield":{"id":"https://openalex.org/subfields/2214","display_name":"Media Technology"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computational-intelligence","display_name":"Computational intelligence","score":0.6703239679336548},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6110998392105103},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.5941081643104553},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5411407947540283},{"id":"https://openalex.org/keywords/scale","display_name":"Scale (ratio)","score":0.532871663570404},{"id":"https://openalex.org/keywords/feature","display_name":"Feature (linguistics)","score":0.5117387771606445},{"id":"https://openalex.org/keywords/geography","display_name":"Geography","score":0.10067984461784363},{"id":"https://openalex.org/keywords/cartography","display_name":"Cartography","score":0.07584109902381897}],"concepts":[{"id":"https://openalex.org/C139502532","wikidata":"https://www.wikidata.org/wiki/Q1122090","display_name":"Computational intelligence","level":2,"score":0.6703239679336548},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6110998392105103},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.5941081643104553},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5411407947540283},{"id":"https://openalex.org/C2778755073","wikidata":"https://www.wikidata.org/wiki/Q10858537","display_name":"Scale (ratio)","level":2,"score":0.532871663570404},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.5117387771606445},{"id":"https://openalex.org/C205649164","wikidata":"https://www.wikidata.org/wiki/Q1071","display_name":"Geography","level":0,"score":0.10067984461784363},{"id":"https://openalex.org/C58640448","wikidata":"https://www.wikidata.org/wiki/Q42515","display_name":"Cartography","level":1,"score":0.07584109902381897},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1007/s40747-025-02025-1","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s40747-025-02025-1","pdf_url":"https://link.springer.com/content/pdf/10.1007/s40747-025-02025-1.pdf","source":{"id":"https://openalex.org/S3035462843","display_name":"Complex & Intelligent Systems","issn_l":"2198-6053","issn":["2198-6053","2199-4536"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Complex & Intelligent Systems","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:c55670c22db1400b8e1e359cf8f588d1","is_oa":true,"landing_page_url":"https://doaj.org/article/c55670c22db1400b8e1e359cf8f588d1","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Complex & Intelligent Systems, Vol 11, Iss 9, Pp 1-15 (2025)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1007/s40747-025-02025-1","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s40747-025-02025-1","pdf_url":"https://link.springer.com/content/pdf/10.1007/s40747-025-02025-1.pdf","source":{"id":"https://openalex.org/S3035462843","display_name":"Complex & Intelligent Systems","issn_l":"2198-6053","issn":["2198-6053","2199-4536"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Complex & Intelligent Systems","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G3696575248","display_name":null,"funder_award_id":"IITP-2025-RS-2022-00156334","funder_id":"https://openalex.org/F4320335489","funder_display_name":"Institute for Information and Communications Technology Promotion"},{"id":"https://openalex.org/G4700831490","display_name":null,"funder_award_id":"2022-","funder_id":"https://openalex.org/F4320335489","funder_display_name":"Institute for Information and Communications Technology Promotion"},{"id":"https://openalex.org/G5928647733","display_name":null,"funder_award_id":"JYTMS20231518","funder_id":"https://openalex.org/F4320326218","funder_display_name":"Foundation of Liaoning Province Education Administration"}],"funders":[{"id":"https://openalex.org/F4320323086","display_name":"Natural Science Foundation of Liaoning Province","ror":null},{"id":"https://openalex.org/F4320326218","display_name":"Foundation of Liaoning Province Education Administration","ror":null},{"id":"https://openalex.org/F4320328359","display_name":"Ministry of Science and ICT, South Korea","ror":"https://ror.org/01wpjm123"},{"id":"https://openalex.org/F4320335489","display_name":"Institute for Information and Communications Technology Promotion","ror":"https://ror.org/01g0hqq23"},{"id":"https://openalex.org/F4320337407","display_name":"Division of Human Resource Development","ror":"https://ror.org/03mamvh39"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4412546057.pdf","grobid_xml":"https://content.openalex.org/works/W4412546057.grobid-xml"},"referenced_works_count":35,"referenced_works":["https://openalex.org/W1522734439","https://openalex.org/W2129882004","https://openalex.org/W2343172899","https://openalex.org/W2463258885","https://openalex.org/W2567961463","https://openalex.org/W2752782242","https://openalex.org/W2763750454","https://openalex.org/W2798054687","https://openalex.org/W2805494981","https://openalex.org/W2884585870","https://openalex.org/W2906155095","https://openalex.org/W2942882625","https://openalex.org/W2963091558","https://openalex.org/W2993219936","https://openalex.org/W2995495466","https://openalex.org/W3115069763","https://openalex.org/W3157129463","https://openalex.org/W3181675592","https://openalex.org/W4214825821","https://openalex.org/W4280564883","https://openalex.org/W4320728002","https://openalex.org/W4327853915","https://openalex.org/W4361285150","https://openalex.org/W4365458737","https://openalex.org/W4385986816","https://openalex.org/W4396973073","https://openalex.org/W4401481079","https://openalex.org/W4402351449","https://openalex.org/W4402483326","https://openalex.org/W4402696770","https://openalex.org/W4406880484","https://openalex.org/W6600704668","https://openalex.org/W6601566401","https://openalex.org/W6654243656","https://openalex.org/W6929104785"],"related_works":["https://openalex.org/W2736674626","https://openalex.org/W2973875853","https://openalex.org/W3147584709","https://openalex.org/W2977677679","https://openalex.org/W1992327129","https://openalex.org/W2381986121","https://openalex.org/W2370918718","https://openalex.org/W1987895166","https://openalex.org/W2033914206","https://openalex.org/W2042327336"],"abstract_inverted_index":{"Alzheimer\u2019s":[0],"disease":[1],"(AD)":[2],"is":[3,108,174],"a":[4,16,33,94],"progressive":[5],"neurodegenerative":[6],"disorder":[7],"characterized":[8],"by":[9],"cognitive":[10,145],"decline,":[11],"with":[12,44,80],"early":[13],"detection":[14],"remaining":[15],"significant":[17,134],"challenge":[18],"due":[19],"to":[20,57,64,85,127],"subtle":[21],"structural":[22,101],"alterations":[23],"in":[24,162],"brain":[25],"MRI":[26,35],"scans.":[27],"To":[28],"address":[29],"this,":[30],"we":[31],"propose":[32],"novel":[34],"classification":[36,129],"model":[37],"that":[38],"effectively":[39],"integrates":[40],"local":[41,60,170],"morphological":[42],"features":[43,173],"global":[45,70,172],"contextual":[46],"information,":[47],"enhancing":[48],"diagnostic":[49],"performance.":[50],"Our":[51],"method":[52],"incorporates":[53],"multi-scale":[54],"convolutional":[55],"layers":[56],"capture":[58],"fine-grained":[59],"patterns,":[61],"dilated":[62],"convolutions":[63],"expand":[65],"receptive":[66],"fields":[67],"for":[68,110,140,143,150],"enriched":[69],"context,":[71],"and":[72,103,148,171],"an":[73,81],"advanced":[74],"attention":[75,79],"mechanism":[76],"combining":[77],"channel":[78],"improved":[82],"SimAM":[83],"module":[84],"facilitate":[86],"intelligent":[87],"feature":[88],"fusion.":[89],"This":[90],"synergistic":[91],"design":[92],"enables":[93],"more":[95],"comprehensive":[96],"representation":[97],"of":[98],"both":[99],"localized":[100],"variations":[102],"their":[104],"broader":[105],"implications,":[106],"which":[107],"crucial":[109],"early-stage":[111,164],"detection.":[112],"Furthermore,":[113],"our":[114,156],"framework":[115],"employs":[116],"three":[117],"specialized":[118],"binary":[119],"classifiers,":[120],"each":[121],"leveraging":[122],"the":[123,167],"proposed":[124],"fusion":[125],"strategy":[126],"enhance":[128],"robustness.":[130],"Experimental":[131],"results":[132],"demonstrate":[133],"performance":[135],"gains,":[136],"achieving":[137],"86.7%":[138],"accuracy":[139],"AD,":[141],"92.6%":[142],"mild":[144],"impairment":[146],"(MCI),":[147],"86.4%":[149],"normal":[151],"control":[152],"(NC)":[153],"classification.":[154],"Notably,":[155],"approach":[157],"outperforms":[158],"existing":[159],"methods,":[160],"particularly":[161],"distinguishing":[163],"abnormalities":[165],"where":[166],"interplay":[168],"between":[169],"most":[175],"critical.":[176]},"counts_by_year":[],"updated_date":"2026-04-21T08:09:41.155169","created_date":"2025-10-10T00:00:00"}