{"id":"https://openalex.org/W3009201613","doi":"https://doi.org/10.1007/s40484-019-0191-8","title":"A simulated annealing approach for resolution guided homogeneous cryo\u2010electron microscopy image selection","display_name":"A simulated annealing approach for resolution guided homogeneous cryo\u2010electron microscopy image selection","publication_year":2020,"publication_date":"2020-03-01","ids":{"openalex":"https://openalex.org/W3009201613","doi":"https://doi.org/10.1007/s40484-019-0191-8","mag":"3009201613","pmid":"https://pubmed.ncbi.nlm.nih.gov/32477613"},"language":"en","primary_location":{"id":"doi:10.1007/s40484-019-0191-8","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s40484-019-0191-8","pdf_url":null,"source":{"id":"https://openalex.org/S4210172333","display_name":"Quantitative Biology","issn_l":"2095-4689","issn":["2095-4689","2095-4697"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Quantitative Biology","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1007/s40484-019-0191-8","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5021398909","display_name":"Jie Shi","orcid":"https://orcid.org/0000-0001-9521-3073"},"institutions":[{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Jie Shi","raw_affiliation_strings":["<!--1--> Department of Computer Science The University of Hong Kong Hong Kong 999077 China","Department of Computer Science The University of Hong Kong Hong Kong 999077 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"<!--1--> Department of Computer Science The University of Hong Kong Hong Kong 999077 China","institution_ids":["https://openalex.org/I889458895"]},{"raw_affiliation_string":"Department of Computer Science The University of Hong Kong Hong Kong 999077 China","institution_ids":["https://openalex.org/I889458895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086172600","display_name":"Xiangrui Zeng","orcid":"https://orcid.org/0000-0002-8589-4474"},"institutions":[{"id":"https://openalex.org/I74973139","display_name":"Carnegie Mellon University","ror":"https://ror.org/05x2bcf33","country_code":"US","type":"education","lineage":["https://openalex.org/I74973139"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiangrui Zeng","raw_affiliation_strings":["<!--2--> Computational Biology Department Carnegie Mellon University Pittsburgh PA 15213 USA","Computational Biology Department Carnegie Mellon University Pittsburgh PA 15213 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"<!--2--> Computational Biology Department Carnegie Mellon University Pittsburgh PA 15213 USA","institution_ids":["https://openalex.org/I74973139"]},{"raw_affiliation_string":"Computational Biology Department Carnegie Mellon University Pittsburgh PA 15213 USA","institution_ids":["https://openalex.org/I74973139"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101966096","display_name":"Rui Jiang","orcid":"https://orcid.org/0000-0001-5007-5746"},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Rui Jiang","raw_affiliation_strings":["<!--3--> Department of Automation Tsinghua University Beijing 100084 China","Department of Automation Tsinghua University Beijing 100084 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"<!--3--> Department of Automation Tsinghua University Beijing 100084 China","institution_ids":["https://openalex.org/I99065089"]},{"raw_affiliation_string":"Department of Automation Tsinghua University Beijing 100084 China","institution_ids":["https://openalex.org/I99065089"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101911266","display_name":"Tao Jiang","orcid":"https://orcid.org/0000-0003-3833-4498"},"institutions":[{"id":"https://openalex.org/I103635307","display_name":"University of California, Riverside","ror":"https://ror.org/03nawhv43","country_code":"US","type":"education","lineage":["https://openalex.org/I103635307"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tao Jiang","raw_affiliation_strings":["<!--4--> Department of Computer Science and Engineering University of California\u2010Riverside Riverside CA 92521 USA","Department of Computer Science and Engineering University of California\u2010Riverside Riverside CA 92521 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"<!--4--> Department of Computer Science and Engineering University of California\u2010Riverside Riverside CA 92521 USA","institution_ids":["https://openalex.org/I103635307"]},{"raw_affiliation_string":"Department of Computer Science and Engineering University of California\u2010Riverside Riverside CA 92521 USA","institution_ids":["https://openalex.org/I103635307"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5000807861","display_name":"Min Xu","orcid":"https://orcid.org/0000-0002-0881-5891"},"institutions":[{"id":"https://openalex.org/I74973139","display_name":"Carnegie Mellon University","ror":"https://ror.org/05x2bcf33","country_code":"US","type":"education","lineage":["https://openalex.org/I74973139"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Min Xu","raw_affiliation_strings":["<!--2--> Computational Biology Department Carnegie Mellon University Pittsburgh PA 15213 USA","Computational Biology Department Carnegie Mellon University Pittsburgh PA 15213 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"<!--2--> Computational Biology Department Carnegie Mellon University Pittsburgh PA 15213 USA","institution_ids":["https://openalex.org/I74973139"]},{"raw_affiliation_string":"Computational Biology Department Carnegie Mellon University Pittsburgh PA 15213 USA","institution_ids":["https://openalex.org/I74973139"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5000807861"],"corresponding_institution_ids":["https://openalex.org/I74973139"],"apc_list":{"value":1990,"currency":"USD","value_usd":1990},"apc_paid":{"value":1990,"currency":"USD","value_usd":1990},"fwci":0.1206,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.67959074,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":95},"biblio":{"volume":"8","issue":"1","first_page":"51","last_page":"63"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10857","display_name":"Advanced Electron Microscopy Techniques and Applications","score":0.9891999959945679,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10857","display_name":"Advanced Electron Microscopy Techniques and Applications","score":0.9891999959945679,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11183","display_name":"Advanced X-ray Imaging Techniques","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12039","display_name":"Electron and X-Ray Spectroscopy Techniques","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2508","display_name":"Surfaces, Coatings and Films"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/simulated-annealing","display_name":"Simulated annealing","score":0.7117469906806946},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6205366849899292},{"id":"https://openalex.org/keywords/homogeneous","display_name":"Homogeneous","score":0.5789315700531006},{"id":"https://openalex.org/keywords/cryo-electron-microscopy","display_name":"Cryo-electron microscopy","score":0.5745751857757568},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5488166213035583},{"id":"https://openalex.org/keywords/resolution","display_name":"Resolution (logic)","score":0.5066311955451965},{"id":"https://openalex.org/keywords/image-quality","display_name":"Image quality","score":0.4854636788368225},{"id":"https://openalex.org/keywords/orientation","display_name":"Orientation (vector space)","score":0.4806027114391327},{"id":"https://openalex.org/keywords/microscopy","display_name":"Microscopy","score":0.45143231749534607},{"id":"https://openalex.org/keywords/image-resolution","display_name":"Image resolution","score":0.44246169924736023},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.4370945692062378},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.4099244475364685},{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.37768301367759705},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.34676527976989746},{"id":"https://openalex.org/keywords/optics","display_name":"Optics","score":0.22384876012802124},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.1958731710910797},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.16152599453926086},{"id":"https://openalex.org/keywords/nuclear-magnetic-resonance","display_name":"Nuclear magnetic resonance","score":0.11799713969230652}],"concepts":[{"id":"https://openalex.org/C126980161","wikidata":"https://www.wikidata.org/wiki/Q863783","display_name":"Simulated annealing","level":2,"score":0.7117469906806946},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6205366849899292},{"id":"https://openalex.org/C66882249","wikidata":"https://www.wikidata.org/wiki/Q169336","display_name":"Homogeneous","level":2,"score":0.5789315700531006},{"id":"https://openalex.org/C20702342","wikidata":"https://www.wikidata.org/wiki/Q5190506","display_name":"Cryo-electron microscopy","level":2,"score":0.5745751857757568},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5488166213035583},{"id":"https://openalex.org/C138268822","wikidata":"https://www.wikidata.org/wiki/Q1051925","display_name":"Resolution (logic)","level":2,"score":0.5066311955451965},{"id":"https://openalex.org/C55020928","wikidata":"https://www.wikidata.org/wiki/Q3813865","display_name":"Image quality","level":3,"score":0.4854636788368225},{"id":"https://openalex.org/C16345878","wikidata":"https://www.wikidata.org/wiki/Q107472979","display_name":"Orientation (vector space)","level":2,"score":0.4806027114391327},{"id":"https://openalex.org/C147080431","wikidata":"https://www.wikidata.org/wiki/Q1074953","display_name":"Microscopy","level":2,"score":0.45143231749534607},{"id":"https://openalex.org/C205372480","wikidata":"https://www.wikidata.org/wiki/Q210521","display_name":"Image resolution","level":2,"score":0.44246169924736023},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.4370945692062378},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.4099244475364685},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.37768301367759705},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.34676527976989746},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.22384876012802124},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.1958731710910797},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.16152599453926086},{"id":"https://openalex.org/C46141821","wikidata":"https://www.wikidata.org/wiki/Q209402","display_name":"Nuclear magnetic resonance","level":1,"score":0.11799713969230652},{"id":"https://openalex.org/C114614502","wikidata":"https://www.wikidata.org/wiki/Q76592","display_name":"Combinatorics","level":1,"score":0.0},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1007/s40484-019-0191-8","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s40484-019-0191-8","pdf_url":null,"source":{"id":"https://openalex.org/S4210172333","display_name":"Quantitative Biology","issn_l":"2095-4689","issn":["2095-4689","2095-4697"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Quantitative Biology","raw_type":"journal-article"},{"id":"pmid:32477613","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32477613","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Quantitative biology (Beijing, China)","raw_type":null},{"id":"pmh:oai:escholarship.org:ark:/13030/qt3zt2z5td","is_oa":false,"landing_page_url":"https://escholarship.org/uc/item/3zt2z5td","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Quantitative Biology, vol 8, iss 1","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7259590","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7259590","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Quant Biol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1007/s40484-019-0191-8","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s40484-019-0191-8","pdf_url":null,"source":{"id":"https://openalex.org/S4210172333","display_name":"Quantitative Biology","issn_l":"2095-4689","issn":["2095-4689","2095-4697"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Quantitative Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G5188192957","display_name":null,"funder_award_id":"P41 GM103712","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G5207768667","display_name":null,"funder_award_id":"P41 GM103712","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W46659105","https://openalex.org/W1492556495","https://openalex.org/W1585565515","https://openalex.org/W1963792029","https://openalex.org/W1985983127","https://openalex.org/W2002924743","https://openalex.org/W2021767145","https://openalex.org/W2021825077","https://openalex.org/W2033170192","https://openalex.org/W2062598925","https://openalex.org/W2068273082","https://openalex.org/W2075923848","https://openalex.org/W2093040750","https://openalex.org/W2097882896","https://openalex.org/W2100455255","https://openalex.org/W2103972113","https://openalex.org/W2104234755","https://openalex.org/W2107255882","https://openalex.org/W2115251427","https://openalex.org/W2118240569","https://openalex.org/W2136581962","https://openalex.org/W2138390185","https://openalex.org/W2165949425","https://openalex.org/W2167488177","https://openalex.org/W2265299935","https://openalex.org/W2292820626","https://openalex.org/W2796200979","https://openalex.org/W2904250082","https://openalex.org/W2904266777","https://openalex.org/W2914275007","https://openalex.org/W4205809008","https://openalex.org/W4206610958","https://openalex.org/W4206762630","https://openalex.org/W4210580908","https://openalex.org/W4231702991"],"related_works":["https://openalex.org/W1988881631","https://openalex.org/W4312462505","https://openalex.org/W1838872057","https://openalex.org/W2277205612","https://openalex.org/W2067147118","https://openalex.org/W2392013129","https://openalex.org/W1996051789","https://openalex.org/W2005223122","https://openalex.org/W2766690409","https://openalex.org/W1520158892"],"abstract_inverted_index":{"BACKGROUND:":[0],"Cryo-electron":[1],"microscopy":[2],"(Cryo-EM)":[3],"and":[4,82,113,120,143,157,171,186,225,229,260],"tomography":[5],"(Cryo-ET)":[6],"have":[7,79],"emerged":[8],"as":[9,243],"important":[10,245],"imaging":[11],"techniques":[12],"for":[13,209,247],"studying":[14],"structures":[15],"of":[16,22,30,66,75,125,148,162,182,201,251,254],"macromolecular":[17,24,31,255],"complexes.":[18],"In":[19],"3D":[20,114,122,151,230],"reconstruction":[21],"large":[23],"complexes,":[25],"many":[26],"2D":[27,112,159,227],"projection":[28],"images":[29,48,58,78,124,161,203,232],"complex":[32,164],"particles":[33],"are":[34,59],"usually":[35],"acquired":[36],"with":[37,53,70,98,105,167,217],"low":[38],"signal-to-noise":[39],"ratio.":[40],"Therefore,":[41],"it":[42],"is":[43,103,137,207],"meaningful":[44],"to":[45,61,92,139,213],"select":[46],"multiple":[47],"containing":[49],"the":[50,67,94,146,199,249],"same":[51],"structure":[52,69],"identical":[54],"orientation.":[55],"The":[56],"selected":[57],"averaged":[60],"produce":[62],"a":[63,87,132],"higher-quality":[64],"representation":[65],"underlying":[68],"improved":[71,145],"resolution.":[72],"Existing":[73],"approaches":[74],"selecting":[76],"such":[77],"limited":[80],"accuracy":[81,179,216],"speed.":[83,220],"METHODS:":[84],"We":[85],"propose":[86],"simulated":[88,119,156,224],"annealing-based":[89],"algorithm":[90],"(SA)":[91],"pick":[93],"homogeneous":[95,202,210],"image":[96,211],"set":[97],"best":[99],"average.":[100],"Its":[101],"performance":[102,147],"compared":[104],"two":[106,190],"baseline":[107,191],"methods":[108],"based":[109],"on":[110,118,150,155,222],"both":[111,223],"datasets.":[115,152],"When":[116],"tested":[117],"experimental":[121,158],"Cryo-ET":[123,231],"Ribosome":[126,163],"complex,":[127],"SA":[128,149,194,206,235],"sometimes":[129],"stopped":[130],"at":[131],"local":[133],"optimal":[134],"solution.":[135],"Restarting":[136],"applied":[138],"settle":[140],"this":[141],"difficulty":[142],"significantly":[144],"RESULTS:":[153],"Experimented":[154],"Cryo-EM":[160,228,259],"datasets":[165],"respectively":[166],"SNR":[168,172],"=":[169,173],"10":[170],"0.5,":[174],"our":[175],"method":[176],"achieved":[177,236],"better":[178,238],"in":[180],"terms":[181],"F-measure,":[183],"resolution":[184,250],"score,":[185],"time":[187],"cost":[188],"than":[189],"methods.":[192],"Additionally,":[193],"shows":[195],"its":[196],"superiority":[197],"when":[198],"proportion":[200],"decreases.":[204],"CONCLUSIONS:":[205],"introduced":[208],"selection":[212],"realize":[214],"higher":[215],"faster":[218],"processing":[219],"Experiments":[221],"real":[226],"demonstrated":[233],"that":[234],"expressively":[237],"performance.":[239],"This":[240],"approach":[241],"serves":[242],"an":[244],"step":[246],"improving":[248],"structural":[252],"recovery":[253],"complexes":[256],"captured":[257],"by":[258],"Cryo-ET.":[261]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2021,"cited_by_count":1}],"updated_date":"2026-07-23T08:03:31.855105","created_date":"2025-10-10T00:00:00"}