{"id":"https://openalex.org/W4394754058","doi":"https://doi.org/10.1007/s13755-024-00287-6","title":"A review of machine learning-based methods for predicting drug\u2013target interactions","display_name":"A review of machine learning-based methods for predicting drug\u2013target interactions","publication_year":2024,"publication_date":"2024-04-12","ids":{"openalex":"https://openalex.org/W4394754058","doi":"https://doi.org/10.1007/s13755-024-00287-6","pmid":"https://pubmed.ncbi.nlm.nih.gov/38617016"},"language":"en","primary_location":{"id":"doi:10.1007/s13755-024-00287-6","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s13755-024-00287-6","pdf_url":null,"source":{"id":"https://openalex.org/S4210178793","display_name":"Health Information Science and Systems","issn_l":"2047-2501","issn":["2047-2501"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Health Information Science and Systems","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11014838/pdf/13755_2024_Article_287.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Wen Shi","orcid":null},"institutions":[{"id":"https://openalex.org/I135237710","display_name":"Zhejiang Normal University","ror":"https://ror.org/01vevwk45","country_code":"CN","type":"education","lineage":["https://openalex.org/I135237710"]},{"id":"https://openalex.org/I37987034","display_name":"Guangzhou University","ror":"https://ror.org/05ar8rn06","country_code":"CN","type":"education","lineage":["https://openalex.org/I37987034"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wen Shi","raw_affiliation_strings":["Cyberspace Institute of Advanced Technology, Guangzhou University, Guangzhou, 510006 China","School of Computer Science and Technology, Zhejiang Normal University, Jinhua, 321004 China","Cyberspace Institute of Advanced Technology, Guangzhou University, Guangzhou, 510006, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cyberspace Institute of Advanced Technology, Guangzhou University, Guangzhou, 510006 China","institution_ids":["https://openalex.org/I37987034"]},{"raw_affiliation_string":"School of Computer Science and Technology, Zhejiang Normal University, Jinhua, 321004 China","institution_ids":["https://openalex.org/I135237710"]},{"raw_affiliation_string":"Cyberspace Institute of Advanced Technology, Guangzhou University, Guangzhou, 510006, China","institution_ids":["https://openalex.org/I37987034"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010058972","display_name":"Hong Yang","orcid":"https://orcid.org/0000-0002-4328-335X"},"institutions":[{"id":"https://openalex.org/I37987034","display_name":"Guangzhou University","ror":"https://ror.org/05ar8rn06","country_code":"CN","type":"education","lineage":["https://openalex.org/I37987034"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hong Yang","raw_affiliation_strings":["Cyberspace Institute of Advanced Technology, Guangzhou University, Guangzhou, 510006 China","Cyberspace Institute of Advanced Technology, Guangzhou University, Guangzhou, 510006, China"],"raw_orcid":"https://orcid.org/0000-0002-4328-335X","affiliations":[{"raw_affiliation_string":"Cyberspace Institute of Advanced Technology, Guangzhou University, Guangzhou, 510006 China","institution_ids":["https://openalex.org/I37987034"]},{"raw_affiliation_string":"Cyberspace Institute of Advanced Technology, Guangzhou University, Guangzhou, 510006, China","institution_ids":["https://openalex.org/I37987034"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006960979","display_name":"Linhai Xie","orcid":"https://orcid.org/0000-0001-8593-2277"},"institutions":[{"id":"https://openalex.org/I4210149540","display_name":"Beijing Proteome Research Center","ror":"https://ror.org/05pp5b412","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210149540"]},{"id":"https://openalex.org/I4391768116","display_name":"State Key Laboratory of Proteomics","ror":"https://ror.org/019bev041","country_code":null,"type":"facility","lineage":["https://openalex.org/I2802541053","https://openalex.org/I4391768116"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Linhai Xie","raw_affiliation_strings":["State Key Laboratory of Proteomics, National Center for Protein Sciences (Beijing), Beijing, 102206 China","State Key Laboratory of Proteomics, National Center for Protein Sciences (Beijing), Beijing, 102206, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Proteomics, National Center for Protein Sciences (Beijing), Beijing, 102206 China","institution_ids":["https://openalex.org/I4210149540"]},{"raw_affiliation_string":"State Key Laboratory of Proteomics, National Center for Protein Sciences (Beijing), Beijing, 102206, China","institution_ids":["https://openalex.org/I4210149540","https://openalex.org/I4391768116"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Xiao-Xia Yin","orcid":null},"institutions":[{"id":"https://openalex.org/I37987034","display_name":"Guangzhou University","ror":"https://ror.org/05ar8rn06","country_code":"CN","type":"education","lineage":["https://openalex.org/I37987034"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiao-Xia Yin","raw_affiliation_strings":["Cyberspace Institute of Advanced Technology, Guangzhou University, Guangzhou, 510006 China","Cyberspace Institute of Advanced Technology, Guangzhou University, Guangzhou, 510006, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cyberspace Institute of Advanced Technology, Guangzhou University, Guangzhou, 510006 China","institution_ids":["https://openalex.org/I37987034"]},{"raw_affiliation_string":"Cyberspace Institute of Advanced Technology, Guangzhou University, Guangzhou, 510006, China","institution_ids":["https://openalex.org/I37987034"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049750015","display_name":"Yanchun Zhang","orcid":"https://orcid.org/0000-0002-5094-5980"},"institutions":[{"id":"https://openalex.org/I135237710","display_name":"Zhejiang Normal University","ror":"https://ror.org/01vevwk45","country_code":"CN","type":"education","lineage":["https://openalex.org/I135237710"]},{"id":"https://openalex.org/I4210136793","display_name":"Peng Cheng Laboratory","ror":"https://ror.org/03qdqbt06","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210136793"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yanchun Zhang","raw_affiliation_strings":["Department of New Networks, Peng Cheng Laboratory, Shenzhen, 518000 China","School of Computer Science and Technology, Zhejiang Normal University, Jinhua, 321004 China","School of Computer Science and Technology, Zhejiang Normal University, Jinhua, 321004, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of New Networks, Peng Cheng Laboratory, Shenzhen, 518000 China","institution_ids":["https://openalex.org/I4210136793"]},{"raw_affiliation_string":"School of Computer Science and Technology, Zhejiang Normal University, Jinhua, 321004 China","institution_ids":["https://openalex.org/I135237710"]},{"raw_affiliation_string":"School of Computer Science and Technology, Zhejiang Normal University, Jinhua, 321004, China","institution_ids":["https://openalex.org/I135237710"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5006960979"],"corresponding_institution_ids":["https://openalex.org/I4210149540","https://openalex.org/I4391768116"],"apc_list":{"value":2790,"currency":"EUR","value_usd":3590},"apc_paid":null,"fwci":9.634,"has_fulltext":true,"cited_by_count":37,"citation_normalized_percentile":{"value":0.98653316,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"12","issue":"1","first_page":"30","last_page":"30"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11948","display_name":"Machine Learning in Materials Science","score":0.9632999897003174,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9545000195503235,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7190163135528564},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.7152490019798279},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.7084038853645325},{"id":"https://openalex.org/keywords/field","display_name":"Field (mathematics)","score":0.5605150461196899},{"id":"https://openalex.org/keywords/deep-learning","display_name":"Deep learning","score":0.5236530303955078},{"id":"https://openalex.org/keywords/representation","display_name":"Representation (politics)","score":0.5083913207054138},{"id":"https://openalex.org/keywords/artificial-neural-network","display_name":"Artificial neural network","score":0.49352848529815674},{"id":"https://openalex.org/keywords/drug-discovery","display_name":"Drug discovery","score":0.48856696486473083},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.10958594083786011}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7190163135528564},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.7152490019798279},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.7084038853645325},{"id":"https://openalex.org/C9652623","wikidata":"https://www.wikidata.org/wiki/Q190109","display_name":"Field (mathematics)","level":2,"score":0.5605150461196899},{"id":"https://openalex.org/C108583219","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep learning","level":2,"score":0.5236530303955078},{"id":"https://openalex.org/C2776359362","wikidata":"https://www.wikidata.org/wiki/Q2145286","display_name":"Representation (politics)","level":3,"score":0.5083913207054138},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.49352848529815674},{"id":"https://openalex.org/C74187038","wikidata":"https://www.wikidata.org/wiki/Q1418791","display_name":"Drug discovery","level":2,"score":0.48856696486473083},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.10958594083786011},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0},{"id":"https://openalex.org/C202444582","wikidata":"https://www.wikidata.org/wiki/Q837863","display_name":"Pure mathematics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0},{"id":"https://openalex.org/C94625758","wikidata":"https://www.wikidata.org/wiki/Q7163","display_name":"Politics","level":2,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1007/s13755-024-00287-6","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s13755-024-00287-6","pdf_url":null,"source":{"id":"https://openalex.org/S4210178793","display_name":"Health Information Science and Systems","issn_l":"2047-2501","issn":["2047-2501"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Health Information Science and Systems","raw_type":"journal-article"},{"id":"pmid:38617016","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38617016","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Health information science and systems","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:11014838","is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11014838/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11014838/pdf/13755_2024_Article_287.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Health Inf Sci Syst","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:11014838","is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11014838/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11014838/pdf/13755_2024_Article_287.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Health Inf Sci Syst","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.5799999833106995}],"awards":[{"id":"https://openalex.org/G4693741493","display_name":null,"funder_award_id":"62376065","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321921","display_name":"Natural Science Foundation of Guangdong Province","ror":null}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W4394754058.pdf"},"referenced_works_count":124,"referenced_works":["https://openalex.org/W363319864","https://openalex.org/W1974884542","https://openalex.org/W1978370150","https://openalex.org/W1993046136","https://openalex.org/W2033906815","https://openalex.org/W2034537627","https://openalex.org/W2035585923","https://openalex.org/W2044002635","https://openalex.org/W2066201825","https://openalex.org/W2079745490","https://openalex.org/W2087726892","https://openalex.org/W2088534163","https://openalex.org/W2106029302","https://openalex.org/W2108069034","https://openalex.org/W2109991441","https://openalex.org/W2126671570","https://openalex.org/W2144000913","https://openalex.org/W2151357092","https://openalex.org/W2153838454","https://openalex.org/W2167901867","https://openalex.org/W2177317049","https://openalex.org/W2204695023","https://openalex.org/W2214074259","https://openalex.org/W2215019161","https://openalex.org/W2320193368","https://openalex.org/W2336207313","https://openalex.org/W2558999090","https://openalex.org/W2561981131","https://openalex.org/W2563206593","https://openalex.org/W2580289839","https://openalex.org/W2605952223","https://openalex.org/W2612835976","https://openalex.org/W2624021832","https://openalex.org/W2751900761","https://openalex.org/W2753953057","https://openalex.org/W2767891136","https://openalex.org/W2770261575","https://openalex.org/W2784213390","https://openalex.org/W2785947426","https://openalex.org/W2793951981","https://openalex.org/W2808177712","https://openalex.org/W2860192827","https://openalex.org/W2884015482","https://openalex.org/W2888273069","https://openalex.org/W2889321024","https://openalex.org/W2893316328","https://openalex.org/W2899788782","https://openalex.org/W2903705089","https://openalex.org/W2962876161","https://openalex.org/W2963609389","https://openalex.org/W2964880320","https://openalex.org/W2966787092","https://openalex.org/W2967815638","https://openalex.org/W2969996838","https://openalex.org/W2989848927","https://openalex.org/W2997096971","https://openalex.org/W2999143619","https://openalex.org/W3000043291","https://openalex.org/W3003302501","https://openalex.org/W3004273418","https://openalex.org/W3004497899","https://openalex.org/W3004604833","https://openalex.org/W3007309629","https://openalex.org/W3010821291","https://openalex.org/W3028589594","https://openalex.org/W3032123378","https://openalex.org/W3039465695","https://openalex.org/W3040062994","https://openalex.org/W3042221936","https://openalex.org/W3084084616","https://openalex.org/W3085429933","https://openalex.org/W3088436919","https://openalex.org/W3088634596","https://openalex.org/W3092712933","https://openalex.org/W3093397714","https://openalex.org/W3096561213","https://openalex.org/W3097411994","https://openalex.org/W3102745472","https://openalex.org/W3122066254","https://openalex.org/W3125641916","https://openalex.org/W3126516421","https://openalex.org/W3129096424","https://openalex.org/W3132796384","https://openalex.org/W3135926638","https://openalex.org/W3158446903","https://openalex.org/W3159176720","https://openalex.org/W3162048269","https://openalex.org/W3167575787","https://openalex.org/W3175599101","https://openalex.org/W3183475563","https://openalex.org/W3183961068","https://openalex.org/W3186179742","https://openalex.org/W3187651051","https://openalex.org/W3201477029","https://openalex.org/W4205167309","https://openalex.org/W4206078729","https://openalex.org/W4206730269","https://openalex.org/W4210311545","https://openalex.org/W4214530112","https://openalex.org/W4220788456","https://openalex.org/W4220796987","https://openalex.org/W4220872781","https://openalex.org/W4225435640","https://openalex.org/W4252436249","https://openalex.org/W4283259285","https://openalex.org/W4283754817","https://openalex.org/W4285601000","https://openalex.org/W4285606578","https://openalex.org/W4289175463","https://openalex.org/W4290877452","https://openalex.org/W4291302359","https://openalex.org/W4294000785","https://openalex.org/W4295808856","https://openalex.org/W4307178567","https://openalex.org/W4308463927","https://openalex.org/W4309490745","https://openalex.org/W4315928565","https://openalex.org/W4318391592","https://openalex.org/W4319159275","https://openalex.org/W4323304388","https://openalex.org/W4365791232","https://openalex.org/W4382632004","https://openalex.org/W6602989878","https://openalex.org/W6725181839"],"related_works":["https://openalex.org/W4375867731","https://openalex.org/W2611989081","https://openalex.org/W2480711475","https://openalex.org/W4230611425","https://openalex.org/W2731899572","https://openalex.org/W2062195135","https://openalex.org/W4294635752","https://openalex.org/W4304166257","https://openalex.org/W4383066092","https://openalex.org/W4380075502"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":15},{"year":2025,"cited_by_count":18},{"year":2024,"cited_by_count":4}],"updated_date":"2026-07-15T18:14:33.161393","created_date":"2025-10-10T00:00:00"}