{"id":"https://openalex.org/W7129531847","doi":"https://doi.org/10.1007/s13721-025-00708-w","title":"Construction of drug safety early warning model for elderly cardiovascular and cerebrovascular diseases based on machine learning","display_name":"Construction of drug safety early warning model for elderly cardiovascular and cerebrovascular diseases based on machine learning","publication_year":2026,"publication_date":"2026-02-17","ids":{"openalex":"https://openalex.org/W7129531847","doi":"https://doi.org/10.1007/s13721-025-00708-w"},"language":"en","primary_location":{"id":"doi:10.1007/s13721-025-00708-w","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s13721-025-00708-w","pdf_url":null,"source":{"id":"https://openalex.org/S4210178532","display_name":"Network Modeling Analysis in Health Informatics and Bioinformatics","issn_l":"2192-6662","issn":["2192-6662","2192-6670"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310321666","host_organization_name":"Springer Vienna","host_organization_lineage":["https://openalex.org/P4310321666","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Vienna","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Network Modeling Analysis in Health Informatics and Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5126217192","display_name":"Ruiquan Chen","orcid":null},"institutions":[{"id":"https://openalex.org/I126520041","display_name":"University of Science and Technology of China","ror":"https://ror.org/04c4dkn09","country_code":"CN","type":"education","lineage":["https://openalex.org/I126520041","https://openalex.org/I19820366"]},{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ruiquan Chen","raw_affiliation_strings":["Department of Automation, University of Science and Technology of China, Hefei, 230026, Anhui, China","The School of Electrical Engineering, Xian Jiaotong University, Xi\u2019an, 710049, Shaanxi, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Automation, University of Science and Technology of China, Hefei, 230026, Anhui, China","institution_ids":["https://openalex.org/I126520041"]},{"raw_affiliation_string":"The School of Electrical Engineering, Xian Jiaotong University, Xi\u2019an, 710049, Shaanxi, China","institution_ids":["https://openalex.org/I87445476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5126229064","display_name":"Kai Qu","orcid":null},"institutions":[{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Kai Qu","raw_affiliation_strings":["The School of Electrical Engineering, Xian Jiaotong University, Xi\u2019an, 710049, Shaanxi, China"],"raw_orcid":"https://orcid.org/0009-0008-4087-6521","affiliations":[{"raw_affiliation_string":"The School of Electrical Engineering, Xian Jiaotong University, Xi\u2019an, 710049, Shaanxi, China","institution_ids":["https://openalex.org/I87445476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050802175","display_name":"Zhequn Zhao","orcid":null},"institutions":[{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhequn Zhao","raw_affiliation_strings":["The School of Electrical Engineering, Xian Jiaotong University, Xi\u2019an, 710049, Shaanxi, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The School of Electrical Engineering, Xian Jiaotong University, Xi\u2019an, 710049, Shaanxi, China","institution_ids":["https://openalex.org/I87445476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110514919","display_name":"Hui Cao","orcid":"https://orcid.org/0009-0004-2594-1015"},"institutions":[{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hui Cao","raw_affiliation_strings":["The School of Electrical Engineering, Xian Jiaotong University, Xi\u2019an, 710049, Shaanxi, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The School of Electrical Engineering, Xian Jiaotong University, Xi\u2019an, 710049, Shaanxi, China","institution_ids":["https://openalex.org/I87445476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5126271853","display_name":"Jie Deng","orcid":null},"institutions":[{"id":"https://openalex.org/I4210131893","display_name":"Second Affiliated Hospital of Xi'an Jiaotong University","ror":"https://ror.org/03aq7kf18","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210131893"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jie Deng","raw_affiliation_strings":["Department of Cardiology, The Second Affiliated Hospital, Xi\u2019an Jiaotong University, Xi\u2019an, 710049, Shaanxi, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, The Second Affiliated Hospital, Xi\u2019an Jiaotong University, Xi\u2019an, 710049, Shaanxi, China","institution_ids":["https://openalex.org/I4210131893"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5126192614","display_name":"Xinghui Li","orcid":null},"institutions":[{"id":"https://openalex.org/I75920027","display_name":"Shaanxi University of Chinese Medicine","ror":"https://ror.org/021r98132","country_code":"CN","type":"education","lineage":["https://openalex.org/I75920027"]},{"id":"https://openalex.org/I9916479","display_name":"Air Force Medical University","ror":"https://ror.org/00ms48f15","country_code":"CN","type":"education","lineage":["https://openalex.org/I9916479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xinghui Li","raw_affiliation_strings":["Department of Radiation Medical Protection, School of Military Preventive Medicine, The Fourth Military Medical University, Xi\u2019an, Shaanxi, China","School of Public Health, Shaanxi University of Chinese Medicine, Xi\u2019an, Shaanxi, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Medical Protection, School of Military Preventive Medicine, The Fourth Military Medical University, Xi\u2019an, Shaanxi, China","institution_ids":["https://openalex.org/I9916479"]},{"raw_affiliation_string":"School of Public Health, Shaanxi University of Chinese Medicine, Xi\u2019an, Shaanxi, China","institution_ids":["https://openalex.org/I75920027"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5126229064"],"corresponding_institution_ids":["https://openalex.org/I87445476"],"apc_list":{"value":2390,"currency":"EUR","value_usd":2990},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.33019992,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"15","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.4099999964237213,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.4099999964237213,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11943","display_name":"Pharmacovigilance and Adverse Drug Reactions","score":0.1793999969959259,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11396","display_name":"Artificial Intelligence in Healthcare","score":0.07959999889135361,"subfield":{"id":"https://openalex.org/subfields/3605","display_name":"Health Information Management"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/interpretability","display_name":"Interpretability","score":0.9079999923706055},{"id":"https://openalex.org/keywords/feature-selection","display_name":"Feature selection","score":0.6039999723434448},{"id":"https://openalex.org/keywords/medical-prescription","display_name":"Medical prescription","score":0.5422000288963318},{"id":"https://openalex.org/keywords/feature","display_name":"Feature (linguistics)","score":0.5170000195503235},{"id":"https://openalex.org/keywords/warning-system","display_name":"Warning system","score":0.4293999969959259},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.4255000054836273},{"id":"https://openalex.org/keywords/health-informatics","display_name":"Health informatics","score":0.41679999232292175},{"id":"https://openalex.org/keywords/comorbidity","display_name":"Comorbidity","score":0.4124999940395355}],"concepts":[{"id":"https://openalex.org/C2781067378","wikidata":"https://www.wikidata.org/wiki/Q17027399","display_name":"Interpretability","level":2,"score":0.9079999923706055},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.7045999765396118},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.60589998960495},{"id":"https://openalex.org/C148483581","wikidata":"https://www.wikidata.org/wiki/Q446488","display_name":"Feature selection","level":2,"score":0.6039999723434448},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5940999984741211},{"id":"https://openalex.org/C2426938","wikidata":"https://www.wikidata.org/wiki/Q3355478","display_name":"Medical prescription","level":2,"score":0.5422000288963318},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.5170000195503235},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4584999978542328},{"id":"https://openalex.org/C29825287","wikidata":"https://www.wikidata.org/wiki/Q1427940","display_name":"Warning system","level":2,"score":0.4293999969959259},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.4255000054836273},{"id":"https://openalex.org/C145642194","wikidata":"https://www.wikidata.org/wiki/Q870895","display_name":"Health informatics","level":3,"score":0.41679999232292175},{"id":"https://openalex.org/C2779159551","wikidata":"https://www.wikidata.org/wiki/Q1414874","display_name":"Comorbidity","level":2,"score":0.4124999940395355},{"id":"https://openalex.org/C133925201","wikidata":"https://www.wikidata.org/wiki/Q188419","display_name":"Life expectancy","level":3,"score":0.33329999446868896},{"id":"https://openalex.org/C45804977","wikidata":"https://www.wikidata.org/wiki/Q7239673","display_name":"Predictive modelling","level":2,"score":0.3262999951839447},{"id":"https://openalex.org/C191630685","wikidata":"https://www.wikidata.org/wiki/Q4027615","display_name":"Informatics","level":2,"score":0.3025999963283539},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3005000054836273},{"id":"https://openalex.org/C54183767","wikidata":"https://www.wikidata.org/wiki/Q10384","display_name":"Geriatrics","level":2,"score":0.2879999876022339},{"id":"https://openalex.org/C2778858636","wikidata":"https://www.wikidata.org/wiki/Q1643563","display_name":"Prescription drug","level":3,"score":0.28139999508857727},{"id":"https://openalex.org/C37616216","wikidata":"https://www.wikidata.org/wiki/Q3218363","display_name":"Lasso (programming language)","level":2,"score":0.26669999957084656},{"id":"https://openalex.org/C2779296788","wikidata":"https://www.wikidata.org/wiki/Q5326904","display_name":"Early warning system","level":3,"score":0.265500009059906},{"id":"https://openalex.org/C545542383","wikidata":"https://www.wikidata.org/wiki/Q2751242","display_name":"Medical emergency","level":1,"score":0.26489999890327454},{"id":"https://openalex.org/C12267149","wikidata":"https://www.wikidata.org/wiki/Q282453","display_name":"Support vector machine","level":2,"score":0.26080000400543213},{"id":"https://openalex.org/C534262118","wikidata":"https://www.wikidata.org/wiki/Q177719","display_name":"Medical diagnosis","level":2,"score":0.2578999996185303},{"id":"https://openalex.org/C12174686","wikidata":"https://www.wikidata.org/wiki/Q1058438","display_name":"Risk assessment","level":2,"score":0.257099986076355},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.2547999918460846},{"id":"https://openalex.org/C110083411","wikidata":"https://www.wikidata.org/wiki/Q1744628","display_name":"Statistical classification","level":2,"score":0.2500999867916107}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/s13721-025-00708-w","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s13721-025-00708-w","pdf_url":null,"source":{"id":"https://openalex.org/S4210178532","display_name":"Network Modeling Analysis in Health Informatics and Bioinformatics","issn_l":"2192-6662","issn":["2192-6662","2192-6670"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310321666","host_organization_name":"Springer Vienna","host_organization_lineage":["https://openalex.org/P4310321666","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Vienna","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Network Modeling Analysis in Health Informatics and Bioinformatics","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.6592741012573242,"display_name":"Good health and well-being"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":28,"referenced_works":["https://openalex.org/W2031564429","https://openalex.org/W2049487246","https://openalex.org/W2055656148","https://openalex.org/W2060282265","https://openalex.org/W2074160386","https://openalex.org/W2114315281","https://openalex.org/W2130483595","https://openalex.org/W2153782867","https://openalex.org/W2156935079","https://openalex.org/W2270416318","https://openalex.org/W2275544563","https://openalex.org/W2323525554","https://openalex.org/W2770006511","https://openalex.org/W2883553986","https://openalex.org/W2907378689","https://openalex.org/W2908393456","https://openalex.org/W2913340405","https://openalex.org/W3001764054","https://openalex.org/W3047890287","https://openalex.org/W3080152705","https://openalex.org/W3118192269","https://openalex.org/W3163006863","https://openalex.org/W4210674553","https://openalex.org/W4211191293","https://openalex.org/W4291003294","https://openalex.org/W4310184741","https://openalex.org/W4387012889","https://openalex.org/W4387866187"],"related_works":[],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-02-19T06:27:42.648592","created_date":"2026-02-18T00:00:00"}