{"id":"https://openalex.org/W2189917453","doi":"https://doi.org/10.1007/s13721-015-0102-5","title":"Bridging miRNAs and pathway analysis in clinical decision support: a case study in nephroblastoma","display_name":"Bridging miRNAs and pathway analysis in clinical decision support: a case study in nephroblastoma","publication_year":2015,"publication_date":"2015-10-22","ids":{"openalex":"https://openalex.org/W2189917453","doi":"https://doi.org/10.1007/s13721-015-0102-5","mag":"2189917453"},"language":"en","primary_location":{"id":"doi:10.1007/s13721-015-0102-5","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s13721-015-0102-5","pdf_url":null,"source":{"id":"https://openalex.org/S4210178532","display_name":"Network Modeling Analysis in Health Informatics and Bioinformatics","issn_l":"2192-6662","issn":["2192-6662","2192-6670"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310321666","host_organization_name":"Springer Vienna","host_organization_lineage":["https://openalex.org/P4310321666","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Vienna","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Network Modeling Analysis in Health Informatics and Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5024944038","display_name":"Lefteris Koumakis","orcid":"https://orcid.org/0000-0002-8442-4630"},"institutions":[{"id":"https://openalex.org/I8901234","display_name":"Foundation for Research and Technology Hellas","ror":"https://ror.org/052rphn09","country_code":"GR","type":"facility","lineage":["https://openalex.org/I8901234"]},{"id":"https://openalex.org/I4210118840","display_name":"Science and Technology Park of Crete","ror":"https://ror.org/02ddqp560","country_code":"GR","type":"other","lineage":["https://openalex.org/I4210118840"]}],"countries":["GR"],"is_corresponding":true,"raw_author_name":"L. Koumakis","raw_affiliation_strings":["Institute of Computers Science (ICS), Foundation for Research and Technology-Hellas (FORTH), 70013, Heraklion, Crete, Greece","Nikolaou Plastira 100, Vassilika Vouton, 70013, Heraklion, Crete, Greece"],"affiliations":[{"raw_affiliation_string":"Institute of Computers Science (ICS), Foundation for Research and Technology-Hellas (FORTH), 70013, Heraklion, Crete, Greece","institution_ids":["https://openalex.org/I8901234"]},{"raw_affiliation_string":"Nikolaou Plastira 100, Vassilika Vouton, 70013, Heraklion, Crete, Greece","institution_ids":["https://openalex.org/I4210118840"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067766558","display_name":"Kamana Sigdel","orcid":null},"institutions":[{"id":"https://openalex.org/I4210122849","display_name":"Philips (Netherlands)","ror":"https://ror.org/02p2bgp27","country_code":"NL","type":"company","lineage":["https://openalex.org/I4210122849"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"K. Sigdel","raw_affiliation_strings":["Philips Research Europe, Eindhoven, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Philips Research Europe, Eindhoven, The Netherlands","institution_ids":["https://openalex.org/I4210122849"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084193547","display_name":"George Potamias","orcid":"https://orcid.org/0000-0001-8129-4191"},"institutions":[{"id":"https://openalex.org/I8901234","display_name":"Foundation for Research and Technology Hellas","ror":"https://ror.org/052rphn09","country_code":"GR","type":"facility","lineage":["https://openalex.org/I8901234"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"G. Potamias","raw_affiliation_strings":["Institute of Computers Science (ICS), Foundation for Research and Technology-Hellas (FORTH), 70013, Heraklion, Crete, Greece"],"affiliations":[{"raw_affiliation_string":"Institute of Computers Science (ICS), Foundation for Research and Technology-Hellas (FORTH), 70013, Heraklion, Crete, Greece","institution_ids":["https://openalex.org/I8901234"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012956979","display_name":"Stelios Sfakianakis","orcid":"https://orcid.org/0000-0001-8424-4157"},"institutions":[{"id":"https://openalex.org/I8901234","display_name":"Foundation for Research and Technology Hellas","ror":"https://ror.org/052rphn09","country_code":"GR","type":"facility","lineage":["https://openalex.org/I8901234"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"S. Sfakianakis","raw_affiliation_strings":["Institute of Computers Science (ICS), Foundation for Research and Technology-Hellas (FORTH), 70013, Heraklion, Crete, Greece"],"affiliations":[{"raw_affiliation_string":"Institute of Computers Science (ICS), Foundation for Research and Technology-Hellas (FORTH), 70013, Heraklion, Crete, Greece","institution_ids":["https://openalex.org/I8901234"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090244866","display_name":"J. van Leeuwen","orcid":"https://orcid.org/0000-0001-8503-6958"},"institutions":[{"id":"https://openalex.org/I4210122849","display_name":"Philips (Netherlands)","ror":"https://ror.org/02p2bgp27","country_code":"NL","type":"company","lineage":["https://openalex.org/I4210122849"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"J. van Leeuwen","raw_affiliation_strings":["Philips Research Europe, Eindhoven, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Philips Research Europe, Eindhoven, The Netherlands","institution_ids":["https://openalex.org/I4210122849"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037012227","display_name":"George Zacharioudakis","orcid":"https://orcid.org/0000-0001-9086-749X"},"institutions":[{"id":"https://openalex.org/I8901234","display_name":"Foundation for Research and Technology Hellas","ror":"https://ror.org/052rphn09","country_code":"GR","type":"facility","lineage":["https://openalex.org/I8901234"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"G. Zacharioudakis","raw_affiliation_strings":["Institute of Computers Science (ICS), Foundation for Research and Technology-Hellas (FORTH), 70013, Heraklion, Crete, Greece"],"affiliations":[{"raw_affiliation_string":"Institute of Computers Science (ICS), Foundation for Research and Technology-Hellas (FORTH), 70013, Heraklion, Crete, Greece","institution_ids":["https://openalex.org/I8901234"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105349013","display_name":"Vassilis Moustakis","orcid":"https://orcid.org/0000-0003-2916-6277"},"institutions":[{"id":"https://openalex.org/I55741626","display_name":"Technical University of Crete","ror":"https://ror.org/03f8bz564","country_code":"GR","type":"education","lineage":["https://openalex.org/I55741626"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"V. Moustakis","raw_affiliation_strings":["School of Production Engineering & Management, Technical University of Crete, 73100, Chania, Greece"],"affiliations":[{"raw_affiliation_string":"School of Production Engineering & Management, Technical University of Crete, 73100, Chania, Greece","institution_ids":["https://openalex.org/I55741626"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113661535","display_name":"Michalis Zervakis","orcid":null},"institutions":[{"id":"https://openalex.org/I55741626","display_name":"Technical University of Crete","ror":"https://ror.org/03f8bz564","country_code":"GR","type":"education","lineage":["https://openalex.org/I55741626"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"M. Zervakis","raw_affiliation_strings":["School of Electronic and Computer Engineering, Technical University of Crete, 73100, Chania, Greece"],"affiliations":[{"raw_affiliation_string":"School of Electronic and Computer Engineering, Technical University of Crete, 73100, Chania, Greece","institution_ids":["https://openalex.org/I55741626"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012580223","display_name":"Anca Bucur","orcid":"https://orcid.org/0000-0002-1940-5652"},"institutions":[{"id":"https://openalex.org/I4210122849","display_name":"Philips (Netherlands)","ror":"https://ror.org/02p2bgp27","country_code":"NL","type":"company","lineage":["https://openalex.org/I4210122849"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"A. Bucur","raw_affiliation_strings":["Philips Research Europe, Eindhoven, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Philips Research Europe, Eindhoven, The Netherlands","institution_ids":["https://openalex.org/I4210122849"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014640458","display_name":"Kostas Marias","orcid":"https://orcid.org/0000-0003-3783-5223"},"institutions":[{"id":"https://openalex.org/I8901234","display_name":"Foundation for Research and Technology Hellas","ror":"https://ror.org/052rphn09","country_code":"GR","type":"facility","lineage":["https://openalex.org/I8901234"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"K. Marias","raw_affiliation_strings":["Institute of Computers Science (ICS), Foundation for Research and Technology-Hellas (FORTH), 70013, Heraklion, Crete, Greece"],"affiliations":[{"raw_affiliation_string":"Institute of Computers Science (ICS), Foundation for Research and Technology-Hellas (FORTH), 70013, Heraklion, Crete, Greece","institution_ids":["https://openalex.org/I8901234"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029830172","display_name":"Norbert Graf","orcid":"https://orcid.org/0000-0002-2248-323X"},"institutions":[{"id":"https://openalex.org/I91712215","display_name":"Saarland University","ror":"https://ror.org/01jdpyv68","country_code":"DE","type":"education","lineage":["https://openalex.org/I91712215"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"N. Graf","raw_affiliation_strings":["Department for Pediatric Oncology and Hematology, Saarland University Hospital, Homburg, Germany"],"affiliations":[{"raw_affiliation_string":"Department for Pediatric Oncology and Hematology, Saarland University Hospital, Homburg, Germany","institution_ids":["https://openalex.org/I91712215"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5087123353","display_name":"Manolis Tsiknakis","orcid":"https://orcid.org/0000-0001-8454-1450"},"institutions":[{"id":"https://openalex.org/I8901234","display_name":"Foundation for Research and Technology Hellas","ror":"https://ror.org/052rphn09","country_code":"GR","type":"facility","lineage":["https://openalex.org/I8901234"]},{"id":"https://openalex.org/I28710699","display_name":"Hellenic Mediterranean University","ror":"https://ror.org/039ce0m20","country_code":"GR","type":"education","lineage":["https://openalex.org/I28710699"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"M. Tsiknakis","raw_affiliation_strings":["Department of Informatics Engineering, Technological Educational Institute of Crete, 71004, Heraklion, Greece","Institute of Computers Science (ICS), Foundation for Research and Technology-Hellas (FORTH), 70013, Heraklion, Crete, Greece"],"affiliations":[{"raw_affiliation_string":"Department of Informatics Engineering, Technological Educational Institute of Crete, 71004, Heraklion, Greece","institution_ids":["https://openalex.org/I28710699"]},{"raw_affiliation_string":"Institute of Computers Science (ICS), Foundation for Research and Technology-Hellas (FORTH), 70013, Heraklion, Crete, Greece","institution_ids":["https://openalex.org/I8901234"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":12,"corresponding_author_ids":["https://openalex.org/A5024944038"],"corresponding_institution_ids":["https://openalex.org/I4210118840","https://openalex.org/I8901234"],"apc_list":{"value":2390,"currency":"EUR","value_usd":2990},"apc_paid":null,"fwci":0.1484,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.56721918,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"4","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12140","display_name":"Renal and related cancers","score":0.9894000291824341,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12140","display_name":"Renal and related cancers","score":0.9894000291824341,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/wilms-tumor","display_name":"Wilms' tumor","score":0.9120990037918091},{"id":"https://openalex.org/keywords/microrna","display_name":"microRNA","score":0.676455020904541},{"id":"https://openalex.org/keywords/decision-tree","display_name":"Decision tree","score":0.6282165050506592},{"id":"https://openalex.org/keywords/phenotype","display_name":"Phenotype","score":0.5257288217544556},{"id":"https://openalex.org/keywords/bridging","display_name":"Bridging (networking)","score":0.5032212138175964},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.4589153528213501},{"id":"https://openalex.org/keywords/clinical-decision-support-system","display_name":"Clinical decision support system","score":0.45310139656066895},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.43138837814331055},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4002637267112732},{"id":"https://openalex.org/keywords/oncology","display_name":"Oncology","score":0.3727308511734009},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.362617552280426},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.347897469997406},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.2881487309932709},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.2659899592399597},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.24537238478660583},{"id":"https://openalex.org/keywords/decision-support-system","display_name":"Decision support system","score":0.24272394180297852},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.1974892020225525},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.1443437933921814}],"concepts":[{"id":"https://openalex.org/C2775999222","wikidata":"https://www.wikidata.org/wiki/Q756289","display_name":"Wilms' tumor","level":2,"score":0.9120990037918091},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.676455020904541},{"id":"https://openalex.org/C84525736","wikidata":"https://www.wikidata.org/wiki/Q831366","display_name":"Decision tree","level":2,"score":0.6282165050506592},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.5257288217544556},{"id":"https://openalex.org/C174348530","wikidata":"https://www.wikidata.org/wiki/Q188635","display_name":"Bridging (networking)","level":2,"score":0.5032212138175964},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.4589153528213501},{"id":"https://openalex.org/C63527458","wikidata":"https://www.wikidata.org/wiki/Q5133829","display_name":"Clinical decision support system","level":3,"score":0.45310139656066895},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.43138837814331055},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4002637267112732},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.3727308511734009},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.362617552280426},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.347897469997406},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2881487309932709},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.2659899592399597},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.24537238478660583},{"id":"https://openalex.org/C107327155","wikidata":"https://www.wikidata.org/wiki/Q330268","display_name":"Decision support system","level":2,"score":0.24272394180297852},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.1974892020225525},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1443437933921814},{"id":"https://openalex.org/C31258907","wikidata":"https://www.wikidata.org/wiki/Q1301371","display_name":"Computer network","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/s13721-015-0102-5","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s13721-015-0102-5","pdf_url":null,"source":{"id":"https://openalex.org/S4210178532","display_name":"Network Modeling Analysis in Health Informatics and Bioinformatics","issn_l":"2192-6662","issn":["2192-6662","2192-6670"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310321666","host_organization_name":"Springer Vienna","host_organization_lineage":["https://openalex.org/P4310321666","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Vienna","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Network Modeling Analysis in Health Informatics and Bioinformatics","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/16","display_name":"Peace, Justice and strong institutions","score":0.699999988079071}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":44,"referenced_works":["https://openalex.org/W144423133","https://openalex.org/W148409012","https://openalex.org/W1487944288","https://openalex.org/W1512098439","https://openalex.org/W1604938182","https://openalex.org/W1970101464","https://openalex.org/W1975724263","https://openalex.org/W1978337436","https://openalex.org/W1982450855","https://openalex.org/W2004271888","https://openalex.org/W2004875493","https://openalex.org/W2014709892","https://openalex.org/W2016106370","https://openalex.org/W2020324446","https://openalex.org/W2023157940","https://openalex.org/W2023820671","https://openalex.org/W2052685738","https://openalex.org/W2054618086","https://openalex.org/W2060860407","https://openalex.org/W2066320835","https://openalex.org/W2081113032","https://openalex.org/W2097563859","https://openalex.org/W2097855313","https://openalex.org/W2098662382","https://openalex.org/W2105679485","https://openalex.org/W2108020239","https://openalex.org/W2111471857","https://openalex.org/W2114004637","https://openalex.org/W2122937570","https://openalex.org/W2123060905","https://openalex.org/W2124343455","https://openalex.org/W2125055259","https://openalex.org/W2133990480","https://openalex.org/W2136943892","https://openalex.org/W2156591213","https://openalex.org/W2158341077","https://openalex.org/W2166373524","https://openalex.org/W2167340209","https://openalex.org/W2306722857","https://openalex.org/W2464079341","https://openalex.org/W3023299375","https://openalex.org/W3103971085","https://openalex.org/W4388252848","https://openalex.org/W6683146096"],"related_works":["https://openalex.org/W4388870064","https://openalex.org/W4235186151","https://openalex.org/W2054685365","https://openalex.org/W2272354214","https://openalex.org/W2120383820","https://openalex.org/W2043010663","https://openalex.org/W2667588871","https://openalex.org/W4248308508","https://openalex.org/W118554674","https://openalex.org/W2757563118"],"abstract_inverted_index":null,"counts_by_year":[{"year":2016,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}