{"id":"https://openalex.org/W2070978538","doi":"https://doi.org/10.1007/s12065-013-0098-7","title":"Reconstructing biological gene regulatory networks: where optimization meets big data","display_name":"Reconstructing biological gene regulatory networks: where optimization meets big data","publication_year":2013,"publication_date":"2013-11-21","ids":{"openalex":"https://openalex.org/W2070978538","doi":"https://doi.org/10.1007/s12065-013-0098-7","mag":"2070978538"},"language":"en","primary_location":{"id":"doi:10.1007/s12065-013-0098-7","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s12065-013-0098-7","pdf_url":null,"source":{"id":"https://openalex.org/S182392644","display_name":"Evolutionary Intelligence","issn_l":"1864-5909","issn":["1864-5909","1864-5917"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Evolutionary Intelligence","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025580494","display_name":"Spencer A. Thomas","orcid":"https://orcid.org/0000-0002-9260-1561"},"institutions":[{"id":"https://openalex.org/I28290843","display_name":"University of Surrey","ror":"https://ror.org/00ks66431","country_code":"GB","type":"education","lineage":["https://openalex.org/I28290843"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Spencer Angus Thomas","raw_affiliation_strings":["Department of Computing, University of Surrey, Guildford, Surrey, GU2 7XH, UK","(Department of Computing, University of Surrey, Guildford, UK)"],"affiliations":[{"raw_affiliation_string":"Department of Computing, University of Surrey, Guildford, Surrey, GU2 7XH, UK","institution_ids":["https://openalex.org/I28290843"]},{"raw_affiliation_string":"(Department of Computing, University of Surrey, Guildford, UK)","institution_ids":["https://openalex.org/I28290843"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5032314861","display_name":"Yaochu Jin","orcid":"https://orcid.org/0000-0003-1100-0631"},"institutions":[{"id":"https://openalex.org/I28290843","display_name":"University of Surrey","ror":"https://ror.org/00ks66431","country_code":"GB","type":"education","lineage":["https://openalex.org/I28290843"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Yaochu Jin","raw_affiliation_strings":["Department of Computing, University of Surrey, Guildford, Surrey, GU2 7XH, UK","(Department of Computing, University of Surrey, Guildford, UK)"],"affiliations":[{"raw_affiliation_string":"Department of Computing, University of Surrey, Guildford, Surrey, GU2 7XH, UK","institution_ids":["https://openalex.org/I28290843"]},{"raw_affiliation_string":"(Department of Computing, University of Surrey, Guildford, UK)","institution_ids":["https://openalex.org/I28290843"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5025580494"],"corresponding_institution_ids":["https://openalex.org/I28290843"],"apc_list":{"value":2390,"currency":"EUR","value_usd":2990},"apc_paid":null,"fwci":3.1443,"has_fulltext":false,"cited_by_count":51,"citation_normalized_percentile":{"value":0.92084107,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"7","issue":"1","first_page":"29","last_page":"47"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9933000206947327,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.8142765760421753},{"id":"https://openalex.org/keywords/big-data","display_name":"Big data","score":0.701872706413269},{"id":"https://openalex.org/keywords/inference","display_name":"Inference","score":0.6722970008850098},{"id":"https://openalex.org/keywords/metaheuristic","display_name":"Metaheuristic","score":0.5453259348869324},{"id":"https://openalex.org/keywords/gene-regulatory-network","display_name":"Gene regulatory network","score":0.5250346660614014},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.45384305715560913},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.4450840950012207},{"id":"https://openalex.org/keywords/systems-biology","display_name":"Systems biology","score":0.4292868375778198},{"id":"https://openalex.org/keywords/optimization-problem","display_name":"Optimization problem","score":0.4190806448459625},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.3806750774383545},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.37697651982307434},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.15072637796401978},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.13616704940795898}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.8142765760421753},{"id":"https://openalex.org/C75684735","wikidata":"https://www.wikidata.org/wiki/Q858810","display_name":"Big data","level":2,"score":0.701872706413269},{"id":"https://openalex.org/C2776214188","wikidata":"https://www.wikidata.org/wiki/Q408386","display_name":"Inference","level":2,"score":0.6722970008850098},{"id":"https://openalex.org/C109718341","wikidata":"https://www.wikidata.org/wiki/Q1385229","display_name":"Metaheuristic","level":2,"score":0.5453259348869324},{"id":"https://openalex.org/C67339327","wikidata":"https://www.wikidata.org/wiki/Q1502576","display_name":"Gene regulatory network","level":4,"score":0.5250346660614014},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.45384305715560913},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.4450840950012207},{"id":"https://openalex.org/C152662350","wikidata":"https://www.wikidata.org/wiki/Q815297","display_name":"Systems biology","level":2,"score":0.4292868375778198},{"id":"https://openalex.org/C137836250","wikidata":"https://www.wikidata.org/wiki/Q984063","display_name":"Optimization problem","level":2,"score":0.4190806448459625},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3806750774383545},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.37697651982307434},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.15072637796401978},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.13616704940795898},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1007/s12065-013-0098-7","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s12065-013-0098-7","pdf_url":null,"source":{"id":"https://openalex.org/S182392644","display_name":"Evolutionary Intelligence","issn_l":"1864-5909","issn":["1864-5909","1864-5917"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Evolutionary Intelligence","raw_type":"journal-article"},{"id":"pmh:oai:alma.44SUR_INST:11139023310002346","is_oa":false,"landing_page_url":null,"pdf_url":null,"source":{"id":"https://openalex.org/S4210197018","display_name":"View","issn_l":"2688-268X","issn":["2688-268X","2688-3988"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":""},{"id":"pmh:oai:pub.uni-bielefeld.de:2978557","is_oa":false,"landing_page_url":"https://pub.uni-bielefeld.de/record/2978557","pdf_url":null,"source":{"id":"https://openalex.org/S4306401670","display_name":"PUB \u2013 Publications at Bielefeld University (Bielefeld University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I20121455","host_organization_name":"Bielefeld University","host_organization_lineage":["https://openalex.org/I20121455"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"http://purl.org/coar/resource_type/c_6501"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":174,"referenced_works":["https://openalex.org/W27581661","https://openalex.org/W61339854","https://openalex.org/W66524200","https://openalex.org/W146929901","https://openalex.org/W160548400","https://openalex.org/W574923274","https://openalex.org/W579399123","https://openalex.org/W632731560","https://openalex.org/W783341876","https://openalex.org/W796559312","https://openalex.org/W989248741","https://openalex.org/W1425806599","https://openalex.org/W1494280056","https://openalex.org/W1502529406","https://openalex.org/W1507015292","https://openalex.org/W1517041043","https://openalex.org/W1527441034","https://openalex.org/W1528177290","https://openalex.org/W1544309315","https://openalex.org/W1553991060","https://openalex.org/W1556472699","https://openalex.org/W1567473651","https://openalex.org/W1574663501","https://openalex.org/W1576660662","https://openalex.org/W1581582023","https://openalex.org/W1585711251","https://openalex.org/W1588375755","https://openalex.org/W1598590531","https://openalex.org/W1599969036","https://openalex.org/W1601098293","https://openalex.org/W1603798699","https://openalex.org/W1604198655","https://openalex.org/W1623155147","https://openalex.org/W1644749979","https://openalex.org/W1695894247","https://openalex.org/W1792149802","https://openalex.org/W1808967201","https://openalex.org/W1833452641","https://openalex.org/W1837652160","https://openalex.org/W1886596768","https://openalex.org/W1896263123","https://openalex.org/W1963522244","https://openalex.org/W1965681731","https://openalex.org/W1970424517","https://openalex.org/W1972764318","https://openalex.org/W1973081915","https://openalex.org/W1978394237","https://openalex.org/W1978394397","https://openalex.org/W1979356488","https://openalex.org/W1979594391","https://openalex.org/W1979769287","https://openalex.org/W1984436984","https://openalex.org/W1989493069","https://openalex.org/W1990552935","https://openalex.org/W2000295051","https://openalex.org/W2001018770","https://openalex.org/W2004608252","https://openalex.org/W2007624520","https://openalex.org/W2008737153","https://openalex.org/W2012731059","https://openalex.org/W2015507194","https://openalex.org/W2015538730","https://openalex.org/W2025525377","https://openalex.org/W2026116367","https://openalex.org/W2026188254","https://openalex.org/W2035245511","https://openalex.org/W2037010474","https://openalex.org/W2039670869","https://openalex.org/W2040558572","https://openalex.org/W2043029113","https://openalex.org/W2053900989","https://openalex.org/W2058221907","https://openalex.org/W2061425021","https://openalex.org/W2062029454","https://openalex.org/W2064118122","https://openalex.org/W2065769502","https://openalex.org/W2070822442","https://openalex.org/W2073297125","https://openalex.org/W2076372398","https://openalex.org/W2080065842","https://openalex.org/W2080218141","https://openalex.org/W2081930221","https://openalex.org/W2082830974","https://openalex.org/W2083986568","https://openalex.org/W2084018951","https://openalex.org/W2084729306","https://openalex.org/W2086852682","https://openalex.org/W2088343152","https://openalex.org/W2089046374","https://openalex.org/W2090739179","https://openalex.org/W2091879895","https://openalex.org/W2094506813","https://openalex.org/W2097571405","https://openalex.org/W2098042719","https://openalex.org/W2098501743","https://openalex.org/W2099380913","https://openalex.org/W2102828335","https://openalex.org/W2110436410","https://openalex.org/W2110699703","https://openalex.org/W2110731438","https://openalex.org/W2111932463","https://openalex.org/W2113979998","https://openalex.org/W2115108153","https://openalex.org/W2115547583","https://openalex.org/W2116661285","https://openalex.org/W2117994680","https://openalex.org/W2118640031","https://openalex.org/W2119948329","https://openalex.org/W2121937120","https://openalex.org/W2122342005","https://openalex.org/W2122708083","https://openalex.org/W2122739151","https://openalex.org/W2124137072","https://openalex.org/W2124349781","https://openalex.org/W2126010462","https://openalex.org/W2126105956","https://openalex.org/W2126551563","https://openalex.org/W2126874285","https://openalex.org/W2127215672","https://openalex.org/W2130130653","https://openalex.org/W2130232722","https://openalex.org/W2131398297","https://openalex.org/W2131463163","https://openalex.org/W2131706188","https://openalex.org/W2131729872","https://openalex.org/W2132828256","https://openalex.org/W2134092975","https://openalex.org/W2135564892","https://openalex.org/W2136605310","https://openalex.org/W2137130066","https://openalex.org/W2140158840","https://openalex.org/W2141239733","https://openalex.org/W2142170851","https://openalex.org/W2143784594","https://openalex.org/W2146506956","https://openalex.org/W2147026702","https://openalex.org/W2148892642","https://openalex.org/W2152964646","https://openalex.org/W2153126872","https://openalex.org/W2153624566","https://openalex.org/W2154815767","https://openalex.org/W2155005783","https://openalex.org/W2155383861","https://openalex.org/W2155389397","https://openalex.org/W2156106639","https://openalex.org/W2156566884","https://openalex.org/W2157886837","https://openalex.org/W2159646183","https://openalex.org/W2161511352","https://openalex.org/W2162202368","https://openalex.org/W2163296115","https://openalex.org/W2165603810","https://openalex.org/W2166920812","https://openalex.org/W2167757882","https://openalex.org/W2182682749","https://openalex.org/W2217720972","https://openalex.org/W2235047952","https://openalex.org/W2281065435","https://openalex.org/W2396226764","https://openalex.org/W2397873694","https://openalex.org/W2501848746","https://openalex.org/W2504533704","https://openalex.org/W2542771499","https://openalex.org/W2611370172","https://openalex.org/W2616627863","https://openalex.org/W2917134690","https://openalex.org/W2963086699","https://openalex.org/W2963269335","https://openalex.org/W3099289621","https://openalex.org/W3103071483","https://openalex.org/W3191596906","https://openalex.org/W4233128219","https://openalex.org/W4233873857","https://openalex.org/W4301900956"],"related_works":["https://openalex.org/W2949927938","https://openalex.org/W4375949242","https://openalex.org/W2029387041","https://openalex.org/W2135896045","https://openalex.org/W1973268559","https://openalex.org/W2884256268","https://openalex.org/W2131025197","https://openalex.org/W2031892952","https://openalex.org/W3108451992","https://openalex.org/W2171763327"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":8},{"year":2014,"cited_by_count":6},{"year":2012,"cited_by_count":2}],"updated_date":"2026-04-05T17:49:38.594831","created_date":"2025-10-10T00:00:00"}