{"id":"https://openalex.org/W3157579223","doi":"https://doi.org/10.1007/s12064-021-00342-w","title":"The essence of life revisited: how theories can shed light on it","display_name":"The essence of life revisited: how theories can shed light on it","publication_year":2021,"publication_date":"2021-05-06","ids":{"openalex":"https://openalex.org/W3157579223","doi":"https://doi.org/10.1007/s12064-021-00342-w","mag":"3157579223","pmid":"https://pubmed.ncbi.nlm.nih.gov/33956294"},"language":"en","primary_location":{"id":"doi:10.1007/s12064-021-00342-w","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s12064-021-00342-w","pdf_url":"https://link.springer.com/content/pdf/10.1007/s12064-021-00342-w.pdf","source":{"id":"https://openalex.org/S12148721","display_name":"Theory in Biosciences","issn_l":"1431-7613","issn":["1431-7613","1611-7530"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Theory in Biosciences","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://link.springer.com/content/pdf/10.1007/s12064-021-00342-w.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5021101856","display_name":"Athel Cornish\u2010Bowden","orcid":"https://orcid.org/0000-0001-6670-3006"},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I21491767","display_name":"Aix-Marseille Universit\u00e9","ror":"https://ror.org/035xkbk20","country_code":"FR","type":"education","lineage":["https://openalex.org/I21491767"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Athel Cornish-Bowden","raw_affiliation_strings":["Aix Marseille Univ, CNRS, BIP, IMM, Marseille, France. athel.cb@gmail.com","Aix Marseille Univ, CNRS, BIP, IMM, Marseille, France"],"raw_orcid":"https://orcid.org/0000-0001-6670-3006","affiliations":[{"raw_affiliation_string":"Aix Marseille Univ, CNRS, BIP, IMM, Marseille, France. athel.cb@gmail.com","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I21491767"]},{"raw_affiliation_string":"Aix Marseille Univ, CNRS, BIP, IMM, Marseille, France","institution_ids":["https://openalex.org/I21491767","https://openalex.org/I1294671590"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5114251983","display_name":"Mar\u0131\u0301a Luz C\u00e1rdenas","orcid":null},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I21491767","display_name":"Aix-Marseille Universit\u00e9","ror":"https://ror.org/035xkbk20","country_code":"FR","type":"education","lineage":["https://openalex.org/I21491767"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Mar\u00eda Luz C\u00e1rdenas","raw_affiliation_strings":["Aix Marseille Univ, CNRS, BIP, IMM, Marseille, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aix Marseille Univ, CNRS, BIP, IMM, Marseille, France","institution_ids":["https://openalex.org/I21491767","https://openalex.org/I1294671590"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5021101856"],"corresponding_institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I21491767"],"apc_list":{"value":2290,"currency":"EUR","value_usd":2890},"apc_paid":null,"fwci":0.9619,"has_fulltext":true,"cited_by_count":10,"citation_normalized_percentile":{"value":0.75813215,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":98},"biblio":{"volume":"141","issue":"2","first_page":"105","last_page":"123"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11445","display_name":"Origins and Evolution of Life","score":0.9987000226974487,"subfield":{"id":"https://openalex.org/subfields/3103","display_name":"Astronomy and Astrophysics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11445","display_name":"Origins and Evolution of Life","score":0.9987000226974487,"subfield":{"id":"https://openalex.org/subfields/3103","display_name":"Astronomy and Astrophysics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9794999957084656,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11252","display_name":"Evolutionary Game Theory and Cooperation","score":0.9728000164031982,"subfield":{"id":"https://openalex.org/subfields/3312","display_name":"Sociology and Political Science"},"field":{"id":"https://openalex.org/fields/33","display_name":"Social Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/philosophy-of-biology","display_name":"Philosophy of biology","score":0.7966576218605042},{"id":"https://openalex.org/keywords/organism","display_name":"Organism","score":0.7854892611503601},{"id":"https://openalex.org/keywords/causation","display_name":"Causation","score":0.6393675804138184},{"id":"https://openalex.org/keywords/closure","display_name":"Closure (psychology)","score":0.5365979671478271},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.4493001401424408},{"id":"https://openalex.org/keywords/three-domain-system","display_name":"Three-domain system","score":0.44364750385284424},{"id":"https://openalex.org/keywords/limit","display_name":"Limit (mathematics)","score":0.43436169624328613},{"id":"https://openalex.org/keywords/epistemology","display_name":"Epistemology","score":0.42551755905151367},{"id":"https://openalex.org/keywords/statistical-physics","display_name":"Statistical physics","score":0.3528881371021271},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.34150615334510803},{"id":"https://openalex.org/keywords/philosophy-of-science","display_name":"Philosophy of science","score":0.24350976943969727},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.19017836451530457},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.15309667587280273},{"id":"https://openalex.org/keywords/economics","display_name":"Economics","score":0.1354004442691803},{"id":"https://openalex.org/keywords/philosophy","display_name":"Philosophy","score":0.11944502592086792},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.09976235032081604}],"concepts":[{"id":"https://openalex.org/C180182882","wikidata":"https://www.wikidata.org/wiki/Q1028964","display_name":"Philosophy of biology","level":3,"score":0.7966576218605042},{"id":"https://openalex.org/C137858568","wikidata":"https://www.wikidata.org/wiki/Q7239","display_name":"Organism","level":2,"score":0.7854892611503601},{"id":"https://openalex.org/C166151441","wikidata":"https://www.wikidata.org/wiki/Q4923601","display_name":"Causation","level":2,"score":0.6393675804138184},{"id":"https://openalex.org/C146834321","wikidata":"https://www.wikidata.org/wiki/Q2979672","display_name":"Closure (psychology)","level":2,"score":0.5365979671478271},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4493001401424408},{"id":"https://openalex.org/C188880781","wikidata":"https://www.wikidata.org/wiki/Q2430501","display_name":"Three-domain system","level":4,"score":0.44364750385284424},{"id":"https://openalex.org/C151201525","wikidata":"https://www.wikidata.org/wiki/Q177239","display_name":"Limit (mathematics)","level":2,"score":0.43436169624328613},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.42551755905151367},{"id":"https://openalex.org/C121864883","wikidata":"https://www.wikidata.org/wiki/Q677916","display_name":"Statistical physics","level":1,"score":0.3528881371021271},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.34150615334510803},{"id":"https://openalex.org/C110099512","wikidata":"https://www.wikidata.org/wiki/Q59115","display_name":"Philosophy of science","level":2,"score":0.24350976943969727},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.19017836451530457},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.15309667587280273},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.1354004442691803},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.11944502592086792},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.09976235032081604},{"id":"https://openalex.org/C34447519","wikidata":"https://www.wikidata.org/wiki/Q179522","display_name":"Market economy","level":1,"score":0.0},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D002384","descriptor_name":"Catalysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002384","descriptor_name":"Catalysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002384","descriptor_name":"Catalysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002384","descriptor_name":"Catalysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1007/s12064-021-00342-w","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s12064-021-00342-w","pdf_url":"https://link.springer.com/content/pdf/10.1007/s12064-021-00342-w.pdf","source":{"id":"https://openalex.org/S12148721","display_name":"Theory in Biosciences","issn_l":"1431-7613","issn":["1431-7613","1611-7530"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Theory in Biosciences","raw_type":"journal-article"},{"id":"pmid:33956294","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33956294","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Theory in biosciences = Theorie in den Biowissenschaften","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:8101340","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8101340","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Theory Biosci","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1007/s12064-021-00342-w","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s12064-021-00342-w","pdf_url":"https://link.springer.com/content/pdf/10.1007/s12064-021-00342-w.pdf","source":{"id":"https://openalex.org/S12148721","display_name":"Theory in Biosciences","issn_l":"1431-7613","issn":["1431-7613","1611-7530"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Theory in Biosciences","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320309911","display_name":"Aix-Marseille Universit\u00e9","ror":"https://ror.org/035xkbk20"},{"id":"https://openalex.org/F4320309966","display_name":"\u00c9cole Normale Sup\u00e9rieure","ror":"https://ror.org/05a0dhs15"},{"id":"https://openalex.org/F4320322892","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3157579223.pdf","grobid_xml":"https://content.openalex.org/works/W3157579223.grobid-xml"},"referenced_works_count":148,"referenced_works":["https://openalex.org/W643863419","https://openalex.org/W808196741","https://openalex.org/W1499059573","https://openalex.org/W1528186923","https://openalex.org/W1534688781","https://openalex.org/W1548526721","https://openalex.org/W1550755354","https://openalex.org/W1576919957","https://openalex.org/W1587819869","https://openalex.org/W1739497080","https://openalex.org/W1916207017","https://openalex.org/W1964465385","https://openalex.org/W1967397809","https://openalex.org/W1971224531","https://openalex.org/W1981047637","https://openalex.org/W1983748245","https://openalex.org/W1985547790","https://openalex.org/W1988747760","https://openalex.org/W1993182958","https://openalex.org/W1994421298","https://openalex.org/W1995384951","https://openalex.org/W1996960605","https://openalex.org/W1998401668","https://openalex.org/W2002575364","https://openalex.org/W2006847904","https://openalex.org/W2007325254","https://openalex.org/W2011617240","https://openalex.org/W2013138671","https://openalex.org/W2013502476","https://openalex.org/W2015423297","https://openalex.org/W2018760730","https://openalex.org/W2019883252","https://openalex.org/W2020454825","https://openalex.org/W2023232735","https://openalex.org/W2026310487","https://openalex.org/W2029539405","https://openalex.org/W2031742656","https://openalex.org/W2032674635","https://openalex.org/W2037339623","https://openalex.org/W2038008442","https://openalex.org/W2040525210","https://openalex.org/W2040746730","https://openalex.org/W2043010404","https://openalex.org/W2044688788","https://openalex.org/W2046880909","https://openalex.org/W2049049899","https://openalex.org/W2049827003","https://openalex.org/W2050110866","https://openalex.org/W2050748701","https://openalex.org/W2054249920","https://openalex.org/W2060945422","https://openalex.org/W2066650872","https://openalex.org/W2067994278","https://openalex.org/W2069856310","https://openalex.org/W2070889260","https://openalex.org/W2071145099","https://openalex.org/W2071847284","https://openalex.org/W2074397232","https://openalex.org/W2074616759","https://openalex.org/W2081345082","https://openalex.org/W2082574693","https://openalex.org/W2083496215","https://openalex.org/W2086604405","https://openalex.org/W2091535033","https://openalex.org/W2097758310","https://openalex.org/W2099192051","https://openalex.org/W2099816198","https://openalex.org/W2102489535","https://openalex.org/W2103731920","https://openalex.org/W2104525153","https://openalex.org/W2104549437","https://openalex.org/W2110107150","https://openalex.org/W2115946139","https://openalex.org/W2119644192","https://openalex.org/W2125611981","https://openalex.org/W2131993994","https://openalex.org/W2135544482","https://openalex.org/W2135699920","https://openalex.org/W2138221986","https://openalex.org/W2141959911","https://openalex.org/W2142283603","https://openalex.org/W2143736326","https://openalex.org/W2148449367","https://openalex.org/W2149489292","https://openalex.org/W2151659911","https://openalex.org/W2152177254","https://openalex.org/W2153965936","https://openalex.org/W2154989771","https://openalex.org/W2157963818","https://openalex.org/W2158631600","https://openalex.org/W2158686686","https://openalex.org/W2161536289","https://openalex.org/W2168916979","https://openalex.org/W2171001867","https://openalex.org/W2174294375","https://openalex.org/W2333229651","https://openalex.org/W2339493109","https://openalex.org/W2383066764","https://openalex.org/W2399606733","https://openalex.org/W2493894436","https://openalex.org/W2504434300","https://openalex.org/W2602557110","https://openalex.org/W2614488821","https://openalex.org/W2624262714","https://openalex.org/W2625557570","https://openalex.org/W2754844655","https://openalex.org/W2758609433","https://openalex.org/W2760541055","https://openalex.org/W2770197421","https://openalex.org/W2772627118","https://openalex.org/W2774254120","https://openalex.org/W2777325725","https://openalex.org/W2804934215","https://openalex.org/W2805359290","https://openalex.org/W2855186055","https://openalex.org/W2884939984","https://openalex.org/W2911908011","https://openalex.org/W2914601079","https://openalex.org/W2916882910","https://openalex.org/W2921617892","https://openalex.org/W2936418497","https://openalex.org/W2939119541","https://openalex.org/W2948947101","https://openalex.org/W2967455602","https://openalex.org/W2968784443","https://openalex.org/W2971139914","https://openalex.org/W2983406079","https://openalex.org/W2984829254","https://openalex.org/W2996553307","https://openalex.org/W2999475014","https://openalex.org/W3000068290","https://openalex.org/W3003442396","https://openalex.org/W3010237700","https://openalex.org/W3010627873","https://openalex.org/W3012079654","https://openalex.org/W3016927940","https://openalex.org/W3087824152","https://openalex.org/W3097103755","https://openalex.org/W3111711003","https://openalex.org/W3112770079","https://openalex.org/W3118320979","https://openalex.org/W3121435341","https://openalex.org/W3128894147","https://openalex.org/W3210261049","https://openalex.org/W4211111865","https://openalex.org/W4230259569","https://openalex.org/W4242261591","https://openalex.org/W6922064526"],"related_works":["https://openalex.org/W2372620761","https://openalex.org/W24843447","https://openalex.org/W2915678288","https://openalex.org/W180255526","https://openalex.org/W2029091459","https://openalex.org/W133423432","https://openalex.org/W2017305847","https://openalex.org/W1937721613","https://openalex.org/W1980413097","https://openalex.org/W3024708790"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2023,"cited_by_count":4},{"year":2021,"cited_by_count":2}],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2025-10-10T00:00:00"}