{"id":"https://openalex.org/W2043806311","doi":"https://doi.org/10.1007/s12021-009-9046-1","title":"Automatic Segmentation of the Human Brain Ventricles from MR Images by Knowledge-Based Region Growing and Trimming","display_name":"Automatic Segmentation of the Human Brain Ventricles from MR Images by Knowledge-Based Region Growing and Trimming","publication_year":2009,"publication_date":"2009-05-15","ids":{"openalex":"https://openalex.org/W2043806311","doi":"https://doi.org/10.1007/s12021-009-9046-1","mag":"2043806311","pmid":"https://pubmed.ncbi.nlm.nih.gov/19449142"},"language":"en","primary_location":{"id":"doi:10.1007/s12021-009-9046-1","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s12021-009-9046-1","pdf_url":null,"source":{"id":"https://openalex.org/S3444786","display_name":"Neuroinformatics","issn_l":"1539-2791","issn":["1539-2791","1559-0089"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101444398","display_name":"Jimin Liu","orcid":"https://orcid.org/0000-0003-3459-8349"},"institutions":[{"id":"https://openalex.org/I4210145138","display_name":"Singapore Bioimaging Consortium","ror":"https://ror.org/046rtjc87","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I2801752549","https://openalex.org/I4210145138"]}],"countries":["SG"],"is_corresponding":true,"raw_author_name":"Jimin Liu","raw_affiliation_strings":["Singapore BioImaging Consortium (SBIC), Singapore, Singapore. liujm@sbic.a-star.edu.sg","Singapore BioImaging Consortium (SBIC), Singapore, Singapore"],"affiliations":[{"raw_affiliation_string":"Singapore BioImaging Consortium (SBIC), Singapore, Singapore. liujm@sbic.a-star.edu.sg","institution_ids":["https://openalex.org/I4210145138"]},{"raw_affiliation_string":"Singapore BioImaging Consortium (SBIC), Singapore, Singapore","institution_ids":["https://openalex.org/I4210145138"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112128304","display_name":"Su Huang","orcid":null},"institutions":[{"id":"https://openalex.org/I4210145138","display_name":"Singapore Bioimaging Consortium","ror":"https://ror.org/046rtjc87","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I2801752549","https://openalex.org/I4210145138"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Su Huang","raw_affiliation_strings":["Singapore BioImaging Consortium (SBIC), Singapore, Singapore"],"affiliations":[{"raw_affiliation_string":"Singapore BioImaging Consortium (SBIC), Singapore, Singapore","institution_ids":["https://openalex.org/I4210145138"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5021552253","display_name":"Wies\u0142aw L. Nowinski","orcid":"https://orcid.org/0000-0003-2869-0608"},"institutions":[{"id":"https://openalex.org/I4210145138","display_name":"Singapore Bioimaging Consortium","ror":"https://ror.org/046rtjc87","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I2801752549","https://openalex.org/I4210145138"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Wieslaw L. Nowinski","raw_affiliation_strings":["Singapore BioImaging Consortium (SBIC), Singapore, Singapore"],"affiliations":[{"raw_affiliation_string":"Singapore BioImaging Consortium (SBIC), Singapore, Singapore","institution_ids":["https://openalex.org/I4210145138"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5101444398"],"corresponding_institution_ids":["https://openalex.org/I4210145138"],"apc_list":{"value":3190,"currency":"EUR","value_usd":4190},"apc_paid":null,"fwci":3.6152,"has_fulltext":false,"cited_by_count":28,"citation_normalized_percentile":{"value":0.93442181,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"7","issue":"2","first_page":"131","last_page":"146"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12702","display_name":"Brain Tumor Detection and Classification","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10036","display_name":"Advanced Neural Network Applications","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/trimming","display_name":"Trimming","score":0.769834041595459},{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.6976511478424072},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6263848543167114},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.616152286529541},{"id":"https://openalex.org/keywords/thresholding","display_name":"Thresholding","score":0.5532665252685547},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.4775836765766144},{"id":"https://openalex.org/keywords/partial-volume","display_name":"Partial volume","score":0.47524404525756836},{"id":"https://openalex.org/keywords/noise","display_name":"Noise (video)","score":0.46620476245880127},{"id":"https://openalex.org/keywords/image-segmentation","display_name":"Image segmentation","score":0.46481260657310486},{"id":"https://openalex.org/keywords/region-of-interest","display_name":"Region of interest","score":0.43419256806373596},{"id":"https://openalex.org/keywords/region-growing","display_name":"Region growing","score":0.41776666045188904},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.4161168932914734},{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.16973987221717834},{"id":"https://openalex.org/keywords/scale-space-segmentation","display_name":"Scale-space segmentation","score":0.15569978952407837}],"concepts":[{"id":"https://openalex.org/C56951928","wikidata":"https://www.wikidata.org/wiki/Q3539213","display_name":"Trimming","level":2,"score":0.769834041595459},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.6976511478424072},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6263848543167114},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.616152286529541},{"id":"https://openalex.org/C191178318","wikidata":"https://www.wikidata.org/wiki/Q2256906","display_name":"Thresholding","level":3,"score":0.5532665252685547},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.4775836765766144},{"id":"https://openalex.org/C82233179","wikidata":"https://www.wikidata.org/wiki/Q2054500","display_name":"Partial volume","level":2,"score":0.47524404525756836},{"id":"https://openalex.org/C99498987","wikidata":"https://www.wikidata.org/wiki/Q2210247","display_name":"Noise (video)","level":3,"score":0.46620476245880127},{"id":"https://openalex.org/C124504099","wikidata":"https://www.wikidata.org/wiki/Q56933","display_name":"Image segmentation","level":3,"score":0.46481260657310486},{"id":"https://openalex.org/C19609008","wikidata":"https://www.wikidata.org/wiki/Q2138203","display_name":"Region of interest","level":2,"score":0.43419256806373596},{"id":"https://openalex.org/C206824153","wikidata":"https://www.wikidata.org/wiki/Q1169834","display_name":"Region growing","level":5,"score":0.41776666045188904},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.4161168932914734},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.16973987221717834},{"id":"https://openalex.org/C65885262","wikidata":"https://www.wikidata.org/wiki/Q7429708","display_name":"Scale-space segmentation","level":4,"score":0.15569978952407837},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001321","descriptor_name":"Autistic Disorder","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001321","descriptor_name":"Autistic Disorder","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001321","descriptor_name":"Autistic Disorder","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002552","descriptor_name":"Cerebral Ventricles","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":false},{"descriptor_ui":"D002552","descriptor_name":"Cerebral Ventricles","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":false},{"descriptor_ui":"D002552","descriptor_name":"Cerebral Ventricles","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":false},{"descriptor_ui":"D002552","descriptor_name":"Cerebral Ventricles","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002552","descriptor_name":"Cerebral Ventricles","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002552","descriptor_name":"Cerebral Ventricles","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008953","descriptor_name":"Models, Anatomic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008953","descriptor_name":"Models, Anatomic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008953","descriptor_name":"Models, Anatomic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/s12021-009-9046-1","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s12021-009-9046-1","pdf_url":null,"source":{"id":"https://openalex.org/S3444786","display_name":"Neuroinformatics","issn_l":"1539-2791","issn":["1539-2791","1559-0089"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroinformatics","raw_type":"journal-article"},{"id":"pmid:19449142","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19449142","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroinformatics","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320335846","display_name":"Biomedical Research Council","ror":"https://ror.org/03xy0wx88"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":48,"referenced_works":["https://openalex.org/W166443869","https://openalex.org/W602564124","https://openalex.org/W1880245544","https://openalex.org/W1891159939","https://openalex.org/W1964124906","https://openalex.org/W1965924747","https://openalex.org/W1972468300","https://openalex.org/W1980764931","https://openalex.org/W1987458109","https://openalex.org/W1988021126","https://openalex.org/W1992379373","https://openalex.org/W1993947467","https://openalex.org/W2002134117","https://openalex.org/W2014262881","https://openalex.org/W2017090646","https://openalex.org/W2020390477","https://openalex.org/W2027252334","https://openalex.org/W2027955893","https://openalex.org/W2031123645","https://openalex.org/W2031491792","https://openalex.org/W2042243471","https://openalex.org/W2042513568","https://openalex.org/W2047352508","https://openalex.org/W2049686996","https://openalex.org/W2049981393","https://openalex.org/W2057518162","https://openalex.org/W2068200113","https://openalex.org/W2078745075","https://openalex.org/W2109928907","https://openalex.org/W2113076747","https://openalex.org/W2113588440","https://openalex.org/W2115113626","https://openalex.org/W2126819661","https://openalex.org/W2128415127","https://openalex.org/W2131426027","https://openalex.org/W2132385004","https://openalex.org/W2136573752","https://openalex.org/W2147646630","https://openalex.org/W2150482737","https://openalex.org/W2150554841","https://openalex.org/W2151050383","https://openalex.org/W2156123885","https://openalex.org/W2162630772","https://openalex.org/W2171493089","https://openalex.org/W2316581687","https://openalex.org/W2615412239","https://openalex.org/W3102998284","https://openalex.org/W3127623214"],"related_works":["https://openalex.org/W2364730859","https://openalex.org/W2020103936","https://openalex.org/W2347731544","https://openalex.org/W2356757465","https://openalex.org/W124243839","https://openalex.org/W2075538113","https://openalex.org/W2118331541","https://openalex.org/W131923485","https://openalex.org/W2536634271","https://openalex.org/W2013921407"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":3}],"updated_date":"2026-04-02T15:55:50.835912","created_date":"2025-10-10T00:00:00"}