{"id":"https://openalex.org/W2043195966","doi":"https://doi.org/10.1007/s11948-012-9411-6","title":"Midstream Modulation in Biotechnology Industry: Redefining What is \u2018Part of the Job\u2019 of Researchers in Industry","display_name":"Midstream Modulation in Biotechnology Industry: Redefining What is \u2018Part of the Job\u2019 of Researchers in Industry","publication_year":2012,"publication_date":"2012-10-24","ids":{"openalex":"https://openalex.org/W2043195966","doi":"https://doi.org/10.1007/s11948-012-9411-6","mag":"2043195966","pmid":"https://pubmed.ncbi.nlm.nih.gov/23096776"},"language":"en","primary_location":{"id":"doi:10.1007/s11948-012-9411-6","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11948-012-9411-6","pdf_url":null,"source":{"id":"https://openalex.org/S14881475","display_name":"Science and Engineering Ethics","issn_l":"1353-3452","issn":["1353-3452","1471-5546"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Science and Engineering Ethics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5069628790","display_name":"Steven M. Flipse","orcid":"https://orcid.org/0000-0002-7400-1490"},"institutions":[{"id":"https://openalex.org/I98358874","display_name":"Delft University of Technology","ror":"https://ror.org/02e2c7k09","country_code":"NL","type":"education","lineage":["https://openalex.org/I98358874"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"Steven M. Flipse","raw_affiliation_strings":["Department of Biotechnology, Delft University of Technology, Julianalaan 67, 2628 BC, Delft, The Netherlands. s.m.flipse@tudelft.nl","Faculty of Applied Sciences, Department of Biotechnology, Section Biotechnology and Society, Delft University of Technology, Julianalaan 67, 2628 BC, Delft, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biotechnology, Delft University of Technology, Julianalaan 67, 2628 BC, Delft, The Netherlands. s.m.flipse@tudelft.nl","institution_ids":["https://openalex.org/I98358874"]},{"raw_affiliation_string":"Faculty of Applied Sciences, Department of Biotechnology, Section Biotechnology and Society, Delft University of Technology, Julianalaan 67, 2628 BC, Delft, The Netherlands","institution_ids":["https://openalex.org/I98358874"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083295746","display_name":"Maarten C. A. van der Sanden","orcid":null},"institutions":[{"id":"https://openalex.org/I98358874","display_name":"Delft University of Technology","ror":"https://ror.org/02e2c7k09","country_code":"NL","type":"education","lineage":["https://openalex.org/I98358874"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Maarten C. A. van der Sanden","raw_affiliation_strings":["Faculty of Applied Sciences, Science Education and Communication, Delft University of Technology, Lorentzweg 1, 2628 CJ, Delft, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Applied Sciences, Science Education and Communication, Delft University of Technology, Lorentzweg 1, 2628 CJ, Delft, The Netherlands","institution_ids":["https://openalex.org/I98358874"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5079665292","display_name":"Patr\u00edcia Osseweijer","orcid":"https://orcid.org/0000-0003-4126-3248"},"institutions":[{"id":"https://openalex.org/I98358874","display_name":"Delft University of Technology","ror":"https://ror.org/02e2c7k09","country_code":"NL","type":"education","lineage":["https://openalex.org/I98358874"]},{"id":"https://openalex.org/I4210127603","display_name":"Cancer Genomics Centre","ror":"https://ror.org/02y9qjz38","country_code":"NL","type":"nonprofit","lineage":["https://openalex.org/I4210127603"]},{"id":"https://openalex.org/I4210101441","display_name":"CSG Centre for Society and the Life Sciences","ror":"https://ror.org/00pavee11","country_code":"NL","type":"facility","lineage":["https://openalex.org/I4210101441"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Patricia Osseweijer","raw_affiliation_strings":["BE-Basic, Julianalaan 67, 2628 BC, Delft, The Netherlands","CSG Centre for Society and the Life Sciences, PO Box 9010, 6500 GL, Nijmegen, The Netherlands","Faculty of Applied Sciences, Department of Biotechnology, Section Biotechnology and Society, Delft University of Technology, Julianalaan 67, 2628 BC, Delft, The Netherlands","Kluyver Centre for Genomics of Industrial Fermentation, PO Box 5057, 2600 GA, Delft, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BE-Basic, Julianalaan 67, 2628 BC, Delft, The Netherlands","institution_ids":["https://openalex.org/I98358874"]},{"raw_affiliation_string":"CSG Centre for Society and the Life Sciences, PO Box 9010, 6500 GL, Nijmegen, The Netherlands","institution_ids":["https://openalex.org/I4210101441"]},{"raw_affiliation_string":"Faculty of Applied Sciences, Department of Biotechnology, Section Biotechnology and Society, Delft University of Technology, Julianalaan 67, 2628 BC, Delft, The Netherlands","institution_ids":["https://openalex.org/I98358874"]},{"raw_affiliation_string":"Kluyver Centre for Genomics of Industrial Fermentation, PO Box 5057, 2600 GA, Delft, The Netherlands","institution_ids":["https://openalex.org/I4210127603"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5069628790"],"corresponding_institution_ids":["https://openalex.org/I98358874"],"apc_list":{"value":2390,"currency":"EUR","value_usd":2990},"apc_paid":null,"fwci":15.5746,"has_fulltext":false,"cited_by_count":66,"citation_normalized_percentile":{"value":0.98670891,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":91,"max":99},"biblio":{"volume":"19","issue":"3","first_page":"1141","last_page":"1164"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14350","display_name":"Innovation, Sustainability, Human-Machine Systems","score":0.940500020980835,"subfield":{"id":"https://openalex.org/subfields/3312","display_name":"Sociology and Political Science"},"field":{"id":"https://openalex.org/fields/33","display_name":"Social Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T14350","display_name":"Innovation, Sustainability, Human-Machine Systems","score":0.940500020980835,"subfield":{"id":"https://openalex.org/subfields/3312","display_name":"Sociology and Political Science"},"field":{"id":"https://openalex.org/fields/33","display_name":"Social Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T14293","display_name":"Biotechnology and Related Fields","score":0.9334999918937683,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13280","display_name":"Biomedical and Engineering Education","score":0.9230999946594238,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/midstream","display_name":"Midstream","score":0.9153671264648438},{"id":"https://openalex.org/keywords/engineering-ethics","display_name":"Engineering ethics","score":0.7112364768981934},{"id":"https://openalex.org/keywords/reflexivity","display_name":"Reflexivity","score":0.5904395580291748},{"id":"https://openalex.org/keywords/philosophy-of-science","display_name":"Philosophy of science","score":0.47679662704467773},{"id":"https://openalex.org/keywords/relevance","display_name":"Relevance (law)","score":0.46312034130096436},{"id":"https://openalex.org/keywords/work","display_name":"Work (physics)","score":0.42667827010154724},{"id":"https://openalex.org/keywords/sociology","display_name":"Sociology","score":0.42338818311691284},{"id":"https://openalex.org/keywords/upstream","display_name":"Upstream (networking)","score":0.41820189356803894},{"id":"https://openalex.org/keywords/public-relations","display_name":"Public relations","score":0.4135130047798157},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.34789857268333435},{"id":"https://openalex.org/keywords/knowledge-management","display_name":"Knowledge management","score":0.335010826587677},{"id":"https://openalex.org/keywords/political-science","display_name":"Political science","score":0.2674442529678345},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.17730015516281128},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.16050836443901062},{"id":"https://openalex.org/keywords/petroleum-industry","display_name":"Petroleum industry","score":0.13139116764068604},{"id":"https://openalex.org/keywords/social-science","display_name":"Social science","score":0.11303824186325073},{"id":"https://openalex.org/keywords/epistemology","display_name":"Epistemology","score":0.10476085543632507}],"concepts":[{"id":"https://openalex.org/C2776941364","wikidata":"https://www.wikidata.org/wiki/Q9751533","display_name":"Midstream","level":3,"score":0.9153671264648438},{"id":"https://openalex.org/C55587333","wikidata":"https://www.wikidata.org/wiki/Q1133029","display_name":"Engineering ethics","level":1,"score":0.7112364768981934},{"id":"https://openalex.org/C13200473","wikidata":"https://www.wikidata.org/wiki/Q2747831","display_name":"Reflexivity","level":2,"score":0.5904395580291748},{"id":"https://openalex.org/C110099512","wikidata":"https://www.wikidata.org/wiki/Q59115","display_name":"Philosophy of science","level":2,"score":0.47679662704467773},{"id":"https://openalex.org/C158154518","wikidata":"https://www.wikidata.org/wiki/Q7310970","display_name":"Relevance (law)","level":2,"score":0.46312034130096436},{"id":"https://openalex.org/C18762648","wikidata":"https://www.wikidata.org/wiki/Q42213","display_name":"Work (physics)","level":2,"score":0.42667827010154724},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.42338818311691284},{"id":"https://openalex.org/C191172861","wikidata":"https://www.wikidata.org/wiki/Q7899321","display_name":"Upstream (networking)","level":2,"score":0.41820189356803894},{"id":"https://openalex.org/C39549134","wikidata":"https://www.wikidata.org/wiki/Q133080","display_name":"Public relations","level":1,"score":0.4135130047798157},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.34789857268333435},{"id":"https://openalex.org/C56739046","wikidata":"https://www.wikidata.org/wiki/Q192060","display_name":"Knowledge management","level":1,"score":0.335010826587677},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.2674442529678345},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.17730015516281128},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.16050836443901062},{"id":"https://openalex.org/C526740375","wikidata":"https://www.wikidata.org/wiki/Q862571","display_name":"Petroleum industry","level":2,"score":0.13139116764068604},{"id":"https://openalex.org/C36289849","wikidata":"https://www.wikidata.org/wiki/Q34749","display_name":"Social science","level":1,"score":0.11303824186325073},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.10476085543632507},{"id":"https://openalex.org/C87717796","wikidata":"https://www.wikidata.org/wiki/Q146326","display_name":"Environmental engineering","level":1,"score":0.0},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001364","descriptor_name":"Awareness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001364","descriptor_name":"Awareness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001364","descriptor_name":"Awareness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001709","descriptor_name":"Biotechnology","qualifier_ui":"Q000941","qualifier_name":"ethics","is_major_topic":false},{"descriptor_ui":"D001709","descriptor_name":"Biotechnology","qualifier_ui":"Q000941","qualifier_name":"ethics","is_major_topic":false},{"descriptor_ui":"D001709","descriptor_name":"Biotechnology","qualifier_ui":"Q000941","qualifier_name":"ethics","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006809","descriptor_name":"Humanities","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006809","descriptor_name":"Humanities","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006809","descriptor_name":"Humanities","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012107","descriptor_name":"Research Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012107","descriptor_name":"Research Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012107","descriptor_name":"Research Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012108","descriptor_name":"Research Personnel","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012108","descriptor_name":"Research Personnel","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012108","descriptor_name":"Research Personnel","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012586","descriptor_name":"Science","qualifier_ui":"Q000941","qualifier_name":"ethics","is_major_topic":false},{"descriptor_ui":"D012586","descriptor_name":"Science","qualifier_ui":"Q000941","qualifier_name":"ethics","is_major_topic":false},{"descriptor_ui":"D012586","descriptor_name":"Science","qualifier_ui":"Q000941","qualifier_name":"ethics","is_major_topic":false},{"descriptor_ui":"D012941","descriptor_name":"Social Responsibility","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012941","descriptor_name":"Social Responsibility","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012941","descriptor_name":"Social Responsibility","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014937","descriptor_name":"Work","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014937","descriptor_name":"Work","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014937","descriptor_name":"Work","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D032984","descriptor_name":"Ethics, Research","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D032984","descriptor_name":"Ethics, Research","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D032984","descriptor_name":"Ethics, Research","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1007/s11948-012-9411-6","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11948-012-9411-6","pdf_url":null,"source":{"id":"https://openalex.org/S14881475","display_name":"Science and Engineering Ethics","issn_l":"1353-3452","issn":["1353-3452","1471-5546"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Science and Engineering Ethics","raw_type":"journal-article"},{"id":"pmid:23096776","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23096776","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Science and engineering ethics","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/9","display_name":"Industry, innovation and infrastructure","score":0.6499999761581421}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":49,"referenced_works":["https://openalex.org/W85397650","https://openalex.org/W600942328","https://openalex.org/W1208766257","https://openalex.org/W1548636740","https://openalex.org/W1896938595","https://openalex.org/W1953414567","https://openalex.org/W1972150770","https://openalex.org/W1974564128","https://openalex.org/W1979590228","https://openalex.org/W1989422091","https://openalex.org/W2006222505","https://openalex.org/W2018001752","https://openalex.org/W2024630473","https://openalex.org/W2044039018","https://openalex.org/W2045708158","https://openalex.org/W2045972147","https://openalex.org/W2048733090","https://openalex.org/W2054413447","https://openalex.org/W2055034160","https://openalex.org/W2063731702","https://openalex.org/W2069415207","https://openalex.org/W2077966292","https://openalex.org/W2079191162","https://openalex.org/W2089784174","https://openalex.org/W2099152065","https://openalex.org/W2100190792","https://openalex.org/W2110058874","https://openalex.org/W2112390359","https://openalex.org/W2125364346","https://openalex.org/W2128264241","https://openalex.org/W2141846678","https://openalex.org/W2147233604","https://openalex.org/W2147781526","https://openalex.org/W2150488544","https://openalex.org/W2150643376","https://openalex.org/W2150740750","https://openalex.org/W2154234908","https://openalex.org/W2154468733","https://openalex.org/W2157465302","https://openalex.org/W2163859225","https://openalex.org/W2165560625","https://openalex.org/W2286884595","https://openalex.org/W2414261561","https://openalex.org/W2501114733","https://openalex.org/W2593713850","https://openalex.org/W2737246833","https://openalex.org/W3128777683","https://openalex.org/W4242883546","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2610011880","https://openalex.org/W4298004968","https://openalex.org/W2996150194","https://openalex.org/W2521693053","https://openalex.org/W2282219576","https://openalex.org/W2802773361","https://openalex.org/W2971453217","https://openalex.org/W2025582374","https://openalex.org/W2906494468","https://openalex.org/W3123861683"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":8},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":7},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":2}],"updated_date":"2026-05-19T08:33:51.333923","created_date":"2025-10-10T00:00:00"}