{"id":"https://openalex.org/W3163963645","doi":"https://doi.org/10.1007/s11548-021-02403-3","title":"Development of a thermal model for irreversible electroporation: an approach to estimate and optimize the IRE protocols","display_name":"Development of a thermal model for irreversible electroporation: an approach to estimate and optimize the IRE protocols","publication_year":2021,"publication_date":"2021-05-25","ids":{"openalex":"https://openalex.org/W3163963645","doi":"https://doi.org/10.1007/s11548-021-02403-3","mag":"3163963645"},"language":"en","primary_location":{"id":"doi:10.1007/s11548-021-02403-3","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s11548-021-02403-3","pdf_url":"https://link.springer.com/content/pdf/10.1007/s11548-021-02403-3.pdf","source":{"id":"https://openalex.org/S181408163","display_name":"International Journal of Computer Assisted Radiology and Surgery","issn_l":"1861-6410","issn":["1861-6410","1861-6429"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Computer Assisted Radiology and Surgery","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://link.springer.com/content/pdf/10.1007/s11548-021-02403-3.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5006460078","display_name":"Girindra Wardhana","orcid":"https://orcid.org/0000-0002-5721-4179"},"institutions":[{"id":"https://openalex.org/I94624287","display_name":"University of Twente","ror":"https://ror.org/006hf6230","country_code":"NL","type":"education","lineage":["https://openalex.org/I94624287"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"Girindra Wardhana","raw_affiliation_strings":["Department of Robotics and Mechatronics, The Faculty of Electrical Engineering, Mathematics and Computer Science, Technical Medical Centre, University of Twente, 7522 NB, Enschede, The Netherlands","Department of Robotics and Mechatronics, The Faculty of Electrical Engineering, Mathematics and Computer Science, Technical Medical Centre, University of Twente, Enschede, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Department of Robotics and Mechatronics, The Faculty of Electrical Engineering, Mathematics and Computer Science, Technical Medical Centre, University of Twente, 7522 NB, Enschede, The Netherlands","institution_ids":["https://openalex.org/I94624287"]},{"raw_affiliation_string":"Department of Robotics and Mechatronics, The Faculty of Electrical Engineering, Mathematics and Computer Science, Technical Medical Centre, University of Twente, Enschede, The Netherlands","institution_ids":["https://openalex.org/I94624287"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070156556","display_name":"Jo\u00e3o Pedro Almeida","orcid":null},"institutions":[{"id":"https://openalex.org/I94624287","display_name":"University of Twente","ror":"https://ror.org/006hf6230","country_code":"NL","type":"education","lineage":["https://openalex.org/I94624287"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Jo\u00e3o Pedro Almeida","raw_affiliation_strings":["Department of Robotics and Mechatronics, The Faculty of Electrical Engineering, Mathematics and Computer Science, Technical Medical Centre, University of Twente, 7522 NB, Enschede, The Netherlands","Department of Robotics and Mechatronics, The Faculty of Electrical Engineering, Mathematics and Computer Science, Technical Medical Centre, University of Twente, Enschede, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Department of Robotics and Mechatronics, The Faculty of Electrical Engineering, Mathematics and Computer Science, Technical Medical Centre, University of Twente, 7522 NB, Enschede, The Netherlands","institution_ids":["https://openalex.org/I94624287"]},{"raw_affiliation_string":"Department of Robotics and Mechatronics, The Faculty of Electrical Engineering, Mathematics and Computer Science, Technical Medical Centre, University of Twente, Enschede, The Netherlands","institution_ids":["https://openalex.org/I94624287"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078462752","display_name":"Momen Abayazid","orcid":"https://orcid.org/0000-0003-1857-5921"},"institutions":[{"id":"https://openalex.org/I94624287","display_name":"University of Twente","ror":"https://ror.org/006hf6230","country_code":"NL","type":"education","lineage":["https://openalex.org/I94624287"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Momen Abayazid","raw_affiliation_strings":["Department of Robotics and Mechatronics, The Faculty of Electrical Engineering, Mathematics and Computer Science, Technical Medical Centre, University of Twente, 7522 NB, Enschede, The Netherlands","Department of Robotics and Mechatronics, The Faculty of Electrical Engineering, Mathematics and Computer Science, Technical Medical Centre, University of Twente, Enschede, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Department of Robotics and Mechatronics, The Faculty of Electrical Engineering, Mathematics and Computer Science, Technical Medical Centre, University of Twente, 7522 NB, Enschede, The Netherlands","institution_ids":["https://openalex.org/I94624287"]},{"raw_affiliation_string":"Department of Robotics and Mechatronics, The Faculty of Electrical Engineering, Mathematics and Computer Science, Technical Medical Centre, University of Twente, Enschede, The Netherlands","institution_ids":["https://openalex.org/I94624287"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5044344644","display_name":"Jurgen J. F\u00fctterer","orcid":"https://orcid.org/0000-0001-6800-2879"},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]},{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]},{"id":"https://openalex.org/I94624287","display_name":"University of Twente","ror":"https://ror.org/006hf6230","country_code":"NL","type":"education","lineage":["https://openalex.org/I94624287"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Jurgen J. F\u00fctterer","raw_affiliation_strings":["Department of Medical Imaging, Radboud University Medical Center Nijmegen, Geert Grooteplein Zuid 10, 6525 GA, Nijmegen, The Netherlands","Department of Robotics and Mechatronics, The Faculty of Electrical Engineering, Mathematics and Computer Science, Technical Medical Centre, University of Twente, 7522 NB, Enschede, The Netherlands","Department of Robotics and Mechatronics, The Faculty of Electrical Engineering, Mathematics and Computer Science, Technical Medical Centre, University of Twente, Enschede, The Netherlands","Department of Medical Imaging, Radboud University Medical Center Nijmegen, Nijmegen, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Department of Medical Imaging, Radboud University Medical Center Nijmegen, Geert Grooteplein Zuid 10, 6525 GA, Nijmegen, The Netherlands","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949"]},{"raw_affiliation_string":"Department of Robotics and Mechatronics, The Faculty of Electrical Engineering, Mathematics and Computer Science, Technical Medical Centre, University of Twente, 7522 NB, Enschede, The Netherlands","institution_ids":["https://openalex.org/I94624287"]},{"raw_affiliation_string":"Department of Robotics and Mechatronics, The Faculty of Electrical Engineering, Mathematics and Computer Science, Technical Medical Centre, University of Twente, Enschede, The Netherlands","institution_ids":["https://openalex.org/I94624287"]},{"raw_affiliation_string":"Department of Medical Imaging, Radboud University Medical Center Nijmegen, Nijmegen, The Netherlands","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5006460078"],"corresponding_institution_ids":["https://openalex.org/I94624287"],"apc_list":{"value":3390,"currency":"EUR","value_usd":4390},"apc_paid":{"value":3390,"currency":"EUR","value_usd":4390},"fwci":1.3006,"has_fulltext":true,"cited_by_count":11,"citation_normalized_percentile":{"value":0.7803463,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":98},"biblio":{"volume":"16","issue":"8","first_page":"1325","last_page":"1334"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11455","display_name":"Microbial Inactivation Methods","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11455","display_name":"Microbial Inactivation Methods","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11920","display_name":"Pulsed Power Technology Applications","score":0.9628999829292297,"subfield":{"id":"https://openalex.org/subfields/2207","display_name":"Control and Systems Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11255","display_name":"Microfluidic and Bio-sensing Technologies","score":0.9621999859809875,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/irreversible-electroporation","display_name":"Irreversible electroporation","score":0.9604183435440063},{"id":"https://openalex.org/keywords/ablation","display_name":"Ablation","score":0.7750411033630371},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.5726975798606873},{"id":"https://openalex.org/keywords/electrode","display_name":"Electrode","score":0.5725038647651672},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.5407505035400391},{"id":"https://openalex.org/keywords/electroporation","display_name":"Electroporation","score":0.5194699168205261},{"id":"https://openalex.org/keywords/thermal-ablation","display_name":"Thermal ablation","score":0.5135786533355713},{"id":"https://openalex.org/keywords/thermal","display_name":"Thermal","score":0.4670953154563904},{"id":"https://openalex.org/keywords/voltage","display_name":"Voltage","score":0.4622494876384735},{"id":"https://openalex.org/keywords/liver-tissue","display_name":"Liver tissue","score":0.4405033588409424},{"id":"https://openalex.org/keywords/response-surface-methodology","display_name":"Response surface methodology","score":0.4162890613079071},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.2321525514125824},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.20594918727874756},{"id":"https://openalex.org/keywords/thermodynamics","display_name":"Thermodynamics","score":0.13148152828216553},{"id":"https://openalex.org/keywords/electrical-engineering","display_name":"Electrical engineering","score":0.10834270715713501},{"id":"https://openalex.org/keywords/chromatography","display_name":"Chromatography","score":0.10102421045303345},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.07701048254966736}],"concepts":[{"id":"https://openalex.org/C2778716261","wikidata":"https://www.wikidata.org/wiki/Q17164846","display_name":"Irreversible electroporation","level":4,"score":0.9604183435440063},{"id":"https://openalex.org/C2778902805","wikidata":"https://www.wikidata.org/wiki/Q322177","display_name":"Ablation","level":2,"score":0.7750411033630371},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.5726975798606873},{"id":"https://openalex.org/C17525397","wikidata":"https://www.wikidata.org/wiki/Q176140","display_name":"Electrode","level":2,"score":0.5725038647651672},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5407505035400391},{"id":"https://openalex.org/C186852380","wikidata":"https://www.wikidata.org/wiki/Q1142521","display_name":"Electroporation","level":3,"score":0.5194699168205261},{"id":"https://openalex.org/C2992234517","wikidata":"https://www.wikidata.org/wiki/Q322177","display_name":"Thermal ablation","level":3,"score":0.5135786533355713},{"id":"https://openalex.org/C204530211","wikidata":"https://www.wikidata.org/wiki/Q752823","display_name":"Thermal","level":2,"score":0.4670953154563904},{"id":"https://openalex.org/C165801399","wikidata":"https://www.wikidata.org/wiki/Q25428","display_name":"Voltage","level":2,"score":0.4622494876384735},{"id":"https://openalex.org/C2992176824","wikidata":"https://www.wikidata.org/wiki/Q9368","display_name":"Liver tissue","level":2,"score":0.4405033588409424},{"id":"https://openalex.org/C150077022","wikidata":"https://www.wikidata.org/wiki/Q3136137","display_name":"Response surface methodology","level":2,"score":0.4162890613079071},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2321525514125824},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.20594918727874756},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.13148152828216553},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.10834270715713501},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.10102421045303345},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.07701048254966736},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.1007/s11548-021-02403-3","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s11548-021-02403-3","pdf_url":"https://link.springer.com/content/pdf/10.1007/s11548-021-02403-3.pdf","source":{"id":"https://openalex.org/S181408163","display_name":"International Journal of Computer Assisted Radiology and Surgery","issn_l":"1861-6410","issn":["1861-6410","1861-6429"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Computer Assisted Radiology and Surgery","raw_type":"journal-article"},{"id":"pmh:oai:ris.utwente.nl:openaire_cris_publications/3bfa02e9-467e-43f1-a004-75ac187db077","is_oa":true,"landing_page_url":"https://research.utwente.nl/en/publications/3bfa02e9-467e-43f1-a004-75ac187db077","pdf_url":"https://ris.utwente.nl/ws/files/278691019/Wardhana2021development.pdf","source":{"id":"https://openalex.org/S4406922991","display_name":"University of Twente Research Information","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Wardhana, G, Almeida, J P, Abayazid, M & F\u00fctterer, J J 2021, 'Development of a thermal model for irreversible electroporation : an approach to estimate and optimize the IRE protocols', International journal of computer assisted radiology and surgery, vol. 16, no. 8, pp. 1325-1334. https://doi.org/10.1007/s11548-021-02403-3","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:pubmedcentral.nih.gov:8295143","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8295143","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Int J Comput Assist Radiol Surg","raw_type":"Text"},{"id":"pmh:oai:repository.ubn.ru.nl:2066/238630","is_oa":false,"landing_page_url":"https://repository.ubn.ru.nl/handle/2066/238630","pdf_url":null,"source":{"id":"https://openalex.org/S4306401067","display_name":"Radboud Repository (Radboud University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I145872427","host_organization_name":"Radboud University Nijmegen","host_organization_lineage":["https://openalex.org/I145872427"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article / Letter to editor"},{"id":"pmh:oai:ris.utwente.nl:publications/3bfa02e9-467e-43f1-a004-75ac187db077","is_oa":false,"landing_page_url":null,"pdf_url":null,"source":{"id":"https://openalex.org/S4406922991","display_name":"University of Twente Research Information","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":""},{"id":"pmh:ru:oai:repository.ubn.ru.nl:2066/238630","is_oa":true,"landing_page_url":"http://hdl.handle.net/2066/238630","pdf_url":null,"source":{"id":"https://openalex.org/S4306401843","display_name":"Data Archiving and Networked Services (DANS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1322597698","host_organization_name":"Royal Netherlands Academy of Arts and Sciences","host_organization_lineage":["https://openalex.org/I1322597698"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Computer Assisted Radiology and Surgery, 16, 1325 - 1334","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1007/s11548-021-02403-3","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s11548-021-02403-3","pdf_url":"https://link.springer.com/content/pdf/10.1007/s11548-021-02403-3.pdf","source":{"id":"https://openalex.org/S181408163","display_name":"International Journal of Computer Assisted Radiology and Surgery","issn_l":"1861-6410","issn":["1861-6410","1861-6429"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Computer Assisted Radiology and Surgery","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.6899999976158142}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3163963645.pdf","grobid_xml":"https://content.openalex.org/works/W3163963645.grobid-xml"},"referenced_works_count":34,"referenced_works":["https://openalex.org/W1503379212","https://openalex.org/W1552814622","https://openalex.org/W1910633347","https://openalex.org/W1981536700","https://openalex.org/W2004944124","https://openalex.org/W2044542264","https://openalex.org/W2054758921","https://openalex.org/W2075371851","https://openalex.org/W2079530087","https://openalex.org/W2084319978","https://openalex.org/W2085802514","https://openalex.org/W2093096884","https://openalex.org/W2105258021","https://openalex.org/W2119456602","https://openalex.org/W2122767824","https://openalex.org/W2170173864","https://openalex.org/W2197139568","https://openalex.org/W2406158068","https://openalex.org/W2494035122","https://openalex.org/W2750918166","https://openalex.org/W2769736168","https://openalex.org/W2779864859","https://openalex.org/W2781392573","https://openalex.org/W2807405692","https://openalex.org/W2976334267","https://openalex.org/W2979330513","https://openalex.org/W3006074294","https://openalex.org/W3007385717","https://openalex.org/W3013527940","https://openalex.org/W3027655064","https://openalex.org/W3036078754","https://openalex.org/W3089177401","https://openalex.org/W4229719081","https://openalex.org/W4254021855"],"related_works":["https://openalex.org/W4254021855","https://openalex.org/W2972545654","https://openalex.org/W2186342673","https://openalex.org/W197636502","https://openalex.org/W2110949835","https://openalex.org/W2253335250","https://openalex.org/W4309284743","https://openalex.org/W38434705","https://openalex.org/W2985074664","https://openalex.org/W4200399261"],"abstract_inverted_index":{"Abstract":[0],"Purpose":[1],"Irreversible":[2],"electroporation":[3],"(IRE)":[4],"is":[5,49,103],"an":[6,192],"emerging":[7],"technique":[8,40],"that":[9,35,68,176,236],"has":[10,133],"drawn":[11],"attention":[12],"in":[13,43,98,106,140,222],"the":[14,36,46,64,70,74,91,95,99,111,125,137,141,158,163,187,207,226,229,238,255],"field":[15],"of":[16,27,38,45,123,127,144,191,196,203,209,212,228,251],"cancer":[17],"treatment.":[18,76],"IRE":[19,66,75,142,188,230,234],"uses":[20],"non-thermal":[21],"electric":[22],"pulses":[23,211],"to":[24,89,136,254],"induce":[25],"death":[26],"cancerous":[28],"cells.":[29],"However,":[30],"recent":[31],"studies":[32],"have":[33],"shown":[34],"application":[37],"this":[39,223],"may":[41],"result":[42,172],"heating":[44],"tissue.":[47,100,256],"There":[48],"still":[50],"room":[51],"for":[52,177],"improving":[53],"its":[54],"efficiency":[55],"and":[56,79,94,130,151,206,215],"defining":[57],"better":[58],"treatment":[59,143],"protocols.":[60,231],"This":[61],"study":[62,224],"investigates":[63],"optimal":[65,171,233],"protocols":[67],"avoiding":[69],"thermal":[71,185,252],"damage":[72,253],"during":[73],"Methods":[77],"Electrode":[78],"pulse":[80],"parameter":[81,126],"are":[82,87],"investigated.":[83],"Finite":[84],"element":[85],"models":[86],"created":[88],"evaluate":[90],"ablation":[92,164,179,239],"area":[93,165,180,240],"temperature":[96,138],"changes":[97],"The":[101,170,219],"model":[102],"validated":[104],"experimentally":[105],"bovine":[107,145],"liver":[108,146],"tissue,":[109],"while":[110],"parameters":[112],"were":[113],"optimized":[114],"using":[115],"response":[116],"surface":[117],"method":[118],"(RSM).":[119],"Results":[120],"From":[121],"analysis":[122],"variance,":[124],"electrode":[128,194],"distance":[129,200],"input":[131,159],"voltage":[132,160],"significant":[134],"effect":[135],"rise":[139],"(":[147,166],"P":[148,152,167],"=":[149,153],"0.020":[150],"0.003":[154],"respectively).":[155],"Meanwhile,":[156],"only":[157],"significantly":[161],"affects":[162],"&lt;":[168],"0.001).":[169],"from":[173],"RSM":[174],"showed":[175],"maximum":[178],"250.82mm":[181],"2":[182],"with":[183,248],"no":[184,249],"damage,":[186],"protocol":[189,235],"consisted":[190],"active":[193],"length":[195],"10":[197,204],"mm,":[198,205],"a":[199],"between":[201],"electrodes":[202],"delivery":[208],"50":[210],"41.21":[213],"\u00b5s":[214],"3000":[216],"V.":[217],"Conclusions":[218],"approach":[220],"presented":[221],"allows":[225],"optimization":[227],"An":[232],"maximizes":[237],"was":[241],"successfully":[242],"calculated":[243],"which":[244],"can":[245],"be":[246],"applied":[247],"risk":[250]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":4}],"updated_date":"2026-03-27T14:29:43.386196","created_date":"2021-06-07T00:00:00"}
