{"id":"https://openalex.org/W7139980383","doi":"https://doi.org/10.1007/s11517-026-03550-y","title":"Hemodynamic performance and blood damage of the Intra-aortic pumps: A CFD-Based investigation","display_name":"Hemodynamic performance and blood damage of the Intra-aortic pumps: A CFD-Based investigation","publication_year":2026,"publication_date":"2026-03-21","ids":{"openalex":"https://openalex.org/W7139980383","doi":"https://doi.org/10.1007/s11517-026-03550-y","pmid":"https://pubmed.ncbi.nlm.nih.gov/41863715"},"language":"en","primary_location":{"id":"doi:10.1007/s11517-026-03550-y","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s11517-026-03550-y","pdf_url":null,"source":{"id":"https://openalex.org/S46300952","display_name":"Medical & Biological Engineering & Computing","issn_l":"0140-0118","issn":["0140-0118","1741-0444"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical & Biological Engineering & Computing","raw_type":"journal-article"},"type":"article","indexed_in":["arxiv","crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1007/s11517-026-03550-y","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5059903650","display_name":"Osman Aycan","orcid":"https://orcid.org/0000-0001-7522-8411"},"institutions":[{"id":"https://openalex.org/I3017902709","display_name":"Zonguldak B\u00fclent Ecevit University","ror":"https://ror.org/01dvabv26","country_code":"TR","type":"education","lineage":["https://openalex.org/I3017902709"]},{"id":"https://openalex.org/I60158472","display_name":"Concordia University","ror":"https://ror.org/0420zvk78","country_code":"CA","type":"education","lineage":["https://openalex.org/I60158472"]}],"countries":["CA","TR"],"is_corresponding":true,"raw_author_name":"Osman Aycan","raw_affiliation_strings":["Department of Mechanical Engineering, Faculty of Engineering, Zonguldak Bulent Ecevit University, Zonguldak, Turkey. osman.aycan@beun.edu.tr","Laboratory of Cardiovascular Fluid Dynamics, Department of Mechanical Industrial and Aerospace Engineering, Concordia University, Montreal, QC, Canada. osman.aycan@beun.edu.tr"],"raw_orcid":"https://orcid.org/0000-0001-7522-8411","affiliations":[{"raw_affiliation_string":"Department of Mechanical Engineering, Faculty of Engineering, Zonguldak Bulent Ecevit University, Zonguldak, Turkey. osman.aycan@beun.edu.tr","institution_ids":["https://openalex.org/I3017902709"]},{"raw_affiliation_string":"Laboratory of Cardiovascular Fluid Dynamics, Department of Mechanical Industrial and Aerospace Engineering, Concordia University, Montreal, QC, Canada. osman.aycan@beun.edu.tr","institution_ids":["https://openalex.org/I60158472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5130266458","display_name":"Yeojin Park","orcid":null},"institutions":[{"id":"https://openalex.org/I60158472","display_name":"Concordia University","ror":"https://ror.org/0420zvk78","country_code":"CA","type":"education","lineage":["https://openalex.org/I60158472"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Yeojin Park","raw_affiliation_strings":["Laboratory of Cardiovascular Fluid Dynamics, Department of Mechanical Industrial and Aerospace Engineering, Concordia University, Montreal, QC, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Cardiovascular Fluid Dynamics, Department of Mechanical Industrial and Aerospace Engineering, Concordia University, Montreal, QC, Canada","institution_ids":["https://openalex.org/I60158472"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5063694103","display_name":"Lyes Kadem","orcid":"https://orcid.org/0000-0001-8796-1274"},"institutions":[{"id":"https://openalex.org/I60158472","display_name":"Concordia University","ror":"https://ror.org/0420zvk78","country_code":"CA","type":"education","lineage":["https://openalex.org/I60158472"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Lyes Kadem","raw_affiliation_strings":["Laboratory of Cardiovascular Fluid Dynamics, Department of Mechanical Industrial and Aerospace Engineering, Concordia University, Montreal, QC, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Cardiovascular Fluid Dynamics, Department of Mechanical Industrial and Aerospace Engineering, Concordia University, Montreal, QC, Canada","institution_ids":["https://openalex.org/I60158472"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5059903650"],"corresponding_institution_ids":["https://openalex.org/I3017902709","https://openalex.org/I60158472"],"apc_list":{"value":2890,"currency":"EUR","value_usd":3690},"apc_paid":{"value":2890,"currency":"EUR","value_usd":3690},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.27157043,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"64","issue":"5","first_page":"1853","last_page":"1869"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10675","display_name":"Mechanical Circulatory Support Devices","score":0.9757999777793884,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10675","display_name":"Mechanical Circulatory Support Devices","score":0.9757999777793884,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10618","display_name":"Aortic Disease and Treatment Approaches","score":0.008999999612569809,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11721","display_name":"Blood properties and coagulation","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/impeller","display_name":"Impeller","score":0.801800012588501},{"id":"https://openalex.org/keywords/hemodynamics","display_name":"Hemodynamics","score":0.6294999718666077},{"id":"https://openalex.org/keywords/hemolysis","display_name":"Hemolysis","score":0.5665000081062317},{"id":"https://openalex.org/keywords/computational-fluid-dynamics","display_name":"Computational fluid dynamics","score":0.4311000108718872},{"id":"https://openalex.org/keywords/flow","display_name":"Flow (mathematics)","score":0.39250001311302185},{"id":"https://openalex.org/keywords/dimensionless-quantity","display_name":"Dimensionless quantity","score":0.3910999894142151},{"id":"https://openalex.org/keywords/blood-flow","display_name":"Blood flow","score":0.3889999985694885}],"concepts":[{"id":"https://openalex.org/C153005164","wikidata":"https://www.wikidata.org/wiki/Q1698700","display_name":"Impeller","level":2,"score":0.801800012588501},{"id":"https://openalex.org/C178853913","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Hemodynamics","level":2,"score":0.6294999718666077},{"id":"https://openalex.org/C2779902561","wikidata":"https://www.wikidata.org/wiki/Q471706","display_name":"Hemolysis","level":2,"score":0.5665000081062317},{"id":"https://openalex.org/C1633027","wikidata":"https://www.wikidata.org/wiki/Q815820","display_name":"Computational fluid dynamics","level":2,"score":0.4311000108718872},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.4108000099658966},{"id":"https://openalex.org/C38349280","wikidata":"https://www.wikidata.org/wiki/Q1434290","display_name":"Flow (mathematics)","level":2,"score":0.39250001311302185},{"id":"https://openalex.org/C24872484","wikidata":"https://www.wikidata.org/wiki/Q126818","display_name":"Dimensionless quantity","level":2,"score":0.3910999894142151},{"id":"https://openalex.org/C158846371","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Blood flow","level":2,"score":0.3889999985694885},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3804999887943268},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.3538999855518341},{"id":"https://openalex.org/C187691185","wikidata":"https://www.wikidata.org/wiki/Q2020720","display_name":"Grid","level":2,"score":0.3490000069141388},{"id":"https://openalex.org/C176217482","wikidata":"https://www.wikidata.org/wiki/Q860554","display_name":"Metric (unit)","level":2,"score":0.34549999237060547},{"id":"https://openalex.org/C21141959","wikidata":"https://www.wikidata.org/wiki/Q657936","display_name":"Shear stress","level":2,"score":0.3418999910354614},{"id":"https://openalex.org/C57879066","wikidata":"https://www.wikidata.org/wiki/Q41217","display_name":"Mechanics","level":1,"score":0.33340001106262207},{"id":"https://openalex.org/C121448008","wikidata":"https://www.wikidata.org/wiki/Q1755722","display_name":"Large eddy simulation","level":3,"score":0.3280999958515167},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.3264000117778778},{"id":"https://openalex.org/C44154836","wikidata":"https://www.wikidata.org/wiki/Q45045","display_name":"Simulation","level":1,"score":0.3190000057220459},{"id":"https://openalex.org/C81917197","wikidata":"https://www.wikidata.org/wiki/Q628760","display_name":"Selection (genetic algorithm)","level":2,"score":0.2736999988555908},{"id":"https://openalex.org/C196558001","wikidata":"https://www.wikidata.org/wiki/Q190132","display_name":"Turbulence","level":2,"score":0.2678000032901764},{"id":"https://openalex.org/C2986265897","wikidata":"https://www.wikidata.org/wiki/Q23852","display_name":"Human physiology","level":2,"score":0.2531999945640564}],"mesh":[{"descriptor_ui":"D001011","descriptor_name":"Aorta","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006353","descriptor_name":"Heart-Assist Devices","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D006439","descriptor_name":"Hemodynamics","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D006461","descriptor_name":"Hemolysis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008955","descriptor_name":"Models, Cardiovascular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057446","descriptor_name":"Hydrodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1007/s11517-026-03550-y","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s11517-026-03550-y","pdf_url":null,"source":{"id":"https://openalex.org/S46300952","display_name":"Medical & Biological Engineering & Computing","issn_l":"0140-0118","issn":["0140-0118","1741-0444"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical & Biological Engineering & Computing","raw_type":"journal-article"},{"id":"pmid:41863715","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41863715","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical & biological engineering & computing","raw_type":null},{"id":"pmh:oai:arXiv.org:2603.26911","is_oa":true,"landing_page_url":"http://arxiv.org/abs/2603.26911","pdf_url":"https://arxiv.org/pdf/2603.26911","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},{"id":"pmh:oai:pubmedcentral.nih.gov:13133241","is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13133241/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Med Biol Eng Comput","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1007/s11517-026-03550-y","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s11517-026-03550-y","pdf_url":null,"source":{"id":"https://openalex.org/S46300952","display_name":"Medical & Biological Engineering & Computing","issn_l":"0140-0118","issn":["0140-0118","1741-0444"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical & Biological Engineering & Computing","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322626","display_name":"T\u00fcrkiye Bilimsel ve Teknolojik Ara\u015ft\u0131rma Kurumu","ror":"https://ror.org/04w9kkr77"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":50,"referenced_works":["https://openalex.org/W1457337077","https://openalex.org/W1507067796","https://openalex.org/W1591139544","https://openalex.org/W1998494385","https://openalex.org/W2016634004","https://openalex.org/W2037113473","https://openalex.org/W2051876212","https://openalex.org/W2129824613","https://openalex.org/W2135543751","https://openalex.org/W2168575889","https://openalex.org/W2342166896","https://openalex.org/W2513556595","https://openalex.org/W2750025445","https://openalex.org/W2826491207","https://openalex.org/W2891587392","https://openalex.org/W2898042790","https://openalex.org/W2920916461","https://openalex.org/W2952830538","https://openalex.org/W2995813004","https://openalex.org/W3017334171","https://openalex.org/W3092286021","https://openalex.org/W3115751089","https://openalex.org/W3182533844","https://openalex.org/W3197803411","https://openalex.org/W4205825238","https://openalex.org/W4206085762","https://openalex.org/W4224007023","https://openalex.org/W4224288408","https://openalex.org/W4225433925","https://openalex.org/W4281746027","https://openalex.org/W4281916479","https://openalex.org/W4283156302","https://openalex.org/W4296129422","https://openalex.org/W4306149476","https://openalex.org/W4306173713","https://openalex.org/W4321374059","https://openalex.org/W4383873717","https://openalex.org/W4386158385","https://openalex.org/W4387297168","https://openalex.org/W4387330639","https://openalex.org/W4387330760","https://openalex.org/W4387709487","https://openalex.org/W4387798846","https://openalex.org/W4390042402","https://openalex.org/W4395066562","https://openalex.org/W4395450374","https://openalex.org/W4399209266","https://openalex.org/W4407908023","https://openalex.org/W4408023651","https://openalex.org/W4408461931"],"related_works":[],"abstract_inverted_index":{"Three":[0],"intra-aortic":[1,207],"blood":[2],"pumps":[3,36,152,208],"were":[4,37,133],"evaluated":[5],"and":[6,22,59,74,92,109,125,150,194,209],"compared":[7],"using":[8,39,67],"CFD":[9,40],"simulations.":[10],"The":[11,30,49,96,130,197],"aim":[12],"of":[13,27,155,191,206,213],"this":[14],"study":[15,64],"is":[16],"to":[17,89],"evaluate":[18],"the":[19,24,28,35,68,79,100,110,121,137,148,169,177,182,186,203,210],"hemodynamic":[20,193],"performance":[21],"calculate":[23],"hemolytic":[25,195],"potential":[26],"pumps.":[29,129],"flow":[31,160,179],"fields":[32],"generated":[33],"by":[34],"simulated":[38],"with":[41],"a":[42,75,86],"wall-modeled":[43],"large":[44],"eddy":[45],"simulation":[46],"(WMLES)":[47],"approach.":[48],"simulations":[50],"produced":[51],"pressure-flow":[52],"curves,":[53],"hydraulic":[54,112],"efficiency,":[55],"shear":[56],"stress":[57],"distributions,":[58],"hemolysis":[60,91],"predictions.":[61],"A":[62,162],"grid":[63],"was":[65,83],"conducted":[66],"Grid":[69],"Convergence":[70],"Index":[71],"(GCI)":[72],"method,":[73],"new":[76],"dimensionless":[77],"parameter,":[78],"Hemolytic":[80],"Number":[81],"(HN),":[82],"introduced":[84],"as":[85],"standardized":[87],"metric":[88],"compare":[90],"universal":[93],"pump":[94,98,139,184],"performance.":[95],"impeller-driven":[97,170,183],"had":[99],"highest-pressure":[101],"head":[102],"(~":[103,114],"800":[104],"Pa":[105],"at":[106,116,158],"4":[107],"L/min)":[108],"best":[111],"efficiency":[113],"6%":[115],"14":[117],"L/min),":[118],"outperforming":[119],"both":[120,192],"single":[122,149],"(maximum":[123,127],"2.7%)":[124],"triplet":[126,151],"2.2%)":[128],"NIH":[131],"values":[132],"also":[134],"lowest":[135],"for":[136,168,202,215],"impeller":[138],"(NIH":[140],"\u2248":[141],"0.0035":[142],"g/100L),":[143],"indicating":[144],"high":[145],"hemocompatibility.":[146],"Both":[147],"showed":[153],"regions":[154],"recirculation,":[156],"particularly":[157],"lower":[159],"rates.":[161,180],"smaller":[163],"HN":[164,172],"indicates":[165],"better":[166],"hemocompatibility;":[167],"pump,":[171],"remains":[173],"below":[174],"1":[175],"across":[176],"investigated":[178],"Overall,":[181],"outperformed":[185],"other":[187],"designs":[188],"in":[189],"terms":[190],"measurements.":[196],"findings":[198],"provide":[199],"valuable":[200],"insights":[201],"future":[204],"development":[205],"personalized":[211],"selection":[212],"devices":[214],"individual":[216],"patients.":[217]},"counts_by_year":[],"updated_date":"2026-07-15T18:14:33.161393","created_date":"2026-03-22T00:00:00"}