{"id":"https://openalex.org/W4413921009","doi":"https://doi.org/10.1007/s11517-025-03418-7","title":"Deep learning-based morphological analysis of human sperm","display_name":"Deep learning-based morphological analysis of human sperm","publication_year":2025,"publication_date":"2025-09-02","ids":{"openalex":"https://openalex.org/W4413921009","doi":"https://doi.org/10.1007/s11517-025-03418-7","pmid":"https://pubmed.ncbi.nlm.nih.gov/40897949"},"language":"en","primary_location":{"id":"doi:10.1007/s11517-025-03418-7","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11517-025-03418-7","pdf_url":null,"source":{"id":"https://openalex.org/S46300952","display_name":"Medical & Biological Engineering & Computing","issn_l":"0140-0118","issn":["0140-0118","1741-0444"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical & Biological Engineering & Computing","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101615740","display_name":"Yiran Xu","orcid":"https://orcid.org/0009-0001-6290-1344"},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yiran Xu","raw_affiliation_strings":["Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, 100084, China"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, 100084, China","institution_ids":["https://openalex.org/I99065089"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078987585","display_name":"Yuqiu Chen","orcid":"https://orcid.org/0000-0001-5591-9389"},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuqiu Chen","raw_affiliation_strings":["Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, 100084, China"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, 100084, China","institution_ids":["https://openalex.org/I99065089"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102905597","display_name":"Boxuan Zhang","orcid":"https://orcid.org/0000-0001-5673-8774"},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Boxuan Zhang","raw_affiliation_strings":["Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, 100084, China"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, 100084, China","institution_ids":["https://openalex.org/I99065089"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057889677","display_name":"Yimo Yan","orcid":"https://orcid.org/0000-0002-0700-3795"},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yimo Yan","raw_affiliation_strings":["Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, 100084, China"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, 100084, China","institution_ids":["https://openalex.org/I99065089"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018740222","display_name":"Hongen Liao","orcid":"https://orcid.org/0000-0003-3847-9347"},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hongen Liao","raw_affiliation_strings":["Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, 100084, China. liao@tsinghua.edu.cn","Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, 100084, China"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, 100084, China. liao@tsinghua.edu.cn","institution_ids":["https://openalex.org/I99065089"]},{"raw_affiliation_string":"Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, 100084, China","institution_ids":["https://openalex.org/I99065089"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5085115861","display_name":"Ran Liu","orcid":"https://orcid.org/0000-0002-6759-5681"},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ran Liu","raw_affiliation_strings":["Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, 100084, China. liuran@tsinghua.edu.cn","Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, 100084, China"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, 100084, China. liuran@tsinghua.edu.cn","institution_ids":["https://openalex.org/I99065089"]},{"raw_affiliation_string":"Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, 100084, China","institution_ids":["https://openalex.org/I99065089"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5101615740"],"corresponding_institution_ids":["https://openalex.org/I99065089"],"apc_list":{"value":2890,"currency":"EUR","value_usd":3690},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.1693654,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"64","issue":"1","first_page":"49","last_page":"59"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9836000204086304,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9836000204086304,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12417","display_name":"Morphological variations and asymmetry","score":0.9483000040054321,"subfield":{"id":"https://openalex.org/subfields/2608","display_name":"Geometry and Topology"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11324","display_name":"Spectroscopy Techniques in Biomedical and Chemical Research","score":0.9240999817848206,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/human-physiology","display_name":"Human physiology","score":0.8225230574607849},{"id":"https://openalex.org/keywords/sperm","display_name":"Sperm","score":0.5813506841659546},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.49923062324523926},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.415929913520813},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3881189823150635},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.11711350083351135}],"concepts":[{"id":"https://openalex.org/C2986265897","wikidata":"https://www.wikidata.org/wiki/Q23852","display_name":"Human physiology","level":2,"score":0.8225230574607849},{"id":"https://openalex.org/C2781087480","wikidata":"https://www.wikidata.org/wiki/Q17145","display_name":"Sperm","level":2,"score":0.5813506841659546},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.49923062324523926},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.415929913520813},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3881189823150635},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.11711350083351135},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013077","descriptor_name":"Sperm Head","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013077","descriptor_name":"Sperm Head","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013094","descriptor_name":"Spermatozoa","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D013094","descriptor_name":"Spermatozoa","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D055101","descriptor_name":"Semen Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D055101","descriptor_name":"Semen Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1007/s11517-025-03418-7","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11517-025-03418-7","pdf_url":null,"source":{"id":"https://openalex.org/S46300952","display_name":"Medical & Biological Engineering & Computing","issn_l":"0140-0118","issn":["0140-0118","1741-0444"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical & Biological Engineering & Computing","raw_type":"journal-article"},{"id":"pmid:40897949","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40897949","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical & biological engineering & computing","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G2893376633","display_name":null,"funder_award_id":"L223035","funder_id":"https://openalex.org/F4320322919","funder_display_name":"Natural Science Foundation of Beijing Municipality"},{"id":"https://openalex.org/G2929194288","display_name":null,"funder_award_id":"2023YFC3502700","funder_id":"https://openalex.org/F4320335774","funder_display_name":"Key Technologies Research and Development Program"},{"id":"https://openalex.org/G4503942162","display_name":null,"funder_award_id":"JCY20200109142805928","funder_id":"https://openalex.org/F4320329793","funder_display_name":"Shenzhen Knowledge Innovation Program"},{"id":"https://openalex.org/G4606646824","display_name":null,"funder_award_id":"U22A20355","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6157130684","display_name":null,"funder_award_id":"82072093","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6661870771","display_name":null,"funder_award_id":"82027807","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8747895672","display_name":null,"funder_award_id":"JCYJ20160428182053361","funder_id":"https://openalex.org/F4320329793","funder_display_name":"Shenzhen Knowledge Innovation Program"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320322919","display_name":"Natural Science Foundation of Beijing Municipality","ror":null},{"id":"https://openalex.org/F4320329793","display_name":"Shenzhen Knowledge Innovation Program","ror":null},{"id":"https://openalex.org/F4320335774","display_name":"Key Technologies Research and Development Program","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":48,"referenced_works":["https://openalex.org/W1563088657","https://openalex.org/W1571564973","https://openalex.org/W1817561967","https://openalex.org/W1901129140","https://openalex.org/W1903029394","https://openalex.org/W1975501761","https://openalex.org/W2022167939","https://openalex.org/W2036892418","https://openalex.org/W2079175854","https://openalex.org/W2091781764","https://openalex.org/W2100402230","https://openalex.org/W2106429976","https://openalex.org/W2117786001","https://openalex.org/W2132822756","https://openalex.org/W2152144623","https://openalex.org/W2161108332","https://openalex.org/W2550182967","https://openalex.org/W2577817188","https://openalex.org/W2588499864","https://openalex.org/W2591573516","https://openalex.org/W2769210209","https://openalex.org/W2783959799","https://openalex.org/W2783961799","https://openalex.org/W2788919350","https://openalex.org/W2790631129","https://openalex.org/W2801396275","https://openalex.org/W2804681539","https://openalex.org/W2886555678","https://openalex.org/W2909240409","https://openalex.org/W2929713667","https://openalex.org/W2954602225","https://openalex.org/W2955463555","https://openalex.org/W2965832108","https://openalex.org/W2970226357","https://openalex.org/W2983336637","https://openalex.org/W2985298239","https://openalex.org/W3001246003","https://openalex.org/W3009521867","https://openalex.org/W3011730019","https://openalex.org/W3013072869","https://openalex.org/W3015113389","https://openalex.org/W3035056746","https://openalex.org/W3048670525","https://openalex.org/W3084904589","https://openalex.org/W3119242620","https://openalex.org/W3120818306","https://openalex.org/W3126996176","https://openalex.org/W3132015460"],"related_works":["https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W4391375266","https://openalex.org/W2082860237","https://openalex.org/W2119695867","https://openalex.org/W2130076355","https://openalex.org/W1990804418","https://openalex.org/W1993764875","https://openalex.org/W2046158694","https://openalex.org/W2788277189"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-02-04T23:10:29.248076","created_date":"2025-10-10T00:00:00"}