{"id":"https://openalex.org/W4394064077","doi":"https://doi.org/10.1007/s11517-024-03065-4","title":"Nucleus segmentation of white blood cells in blood smear images by modeling the pixels\u2019 intensities as a set of three Gaussian distributions","display_name":"Nucleus segmentation of white blood cells in blood smear images by modeling the pixels\u2019 intensities as a set of three Gaussian distributions","publication_year":2024,"publication_date":"2024-04-07","ids":{"openalex":"https://openalex.org/W4394064077","doi":"https://doi.org/10.1007/s11517-024-03065-4","pmid":"https://pubmed.ncbi.nlm.nih.gov/38584206"},"language":"en","primary_location":{"id":"doi:10.1007/s11517-024-03065-4","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11517-024-03065-4","pdf_url":null,"source":{"id":"https://openalex.org/S46300952","display_name":"Medical & Biological Engineering & Computing","issn_l":"0140-0118","issn":["0140-0118","1741-0444"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical & Biological Engineering & Computing","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022867602","display_name":"Farid Garc\u00eda\u2010Lamont","orcid":"https://orcid.org/0000-0002-9739-3802"},"institutions":[{"id":"https://openalex.org/I179647637","display_name":"Universidad Aut\u00f3noma del Estado de M\u00e9xico","ror":"https://ror.org/0079gpv38","country_code":"MX","type":"education","lineage":["https://openalex.org/I179647637"]},{"id":"https://openalex.org/I31466659","display_name":"Chapingo Autonomous University","ror":"https://ror.org/04ctjby61","country_code":"MX","type":"education","lineage":["https://openalex.org/I31466659"]}],"countries":["MX"],"is_corresponding":true,"raw_author_name":"Farid Garcia-Lamont","raw_affiliation_strings":["Centro Universitario UAEM Texcoco, Universidad Autonoma del Estado de Mexico, Av. Jardin Zumpango, s/n, Fraccionamiento El Tejocote, Texcoco, CP 56259, Estado de Mexico, Mexico. fgarcial@uaemex.mx","Centro Universitario UAEM Texcoco, Universidad Autonoma del Estado de Mexico, Av. Jardin Zumpango, s/n, Fraccionamiento El Tejocote, Texcoco, CP 56259, Estado de Mexico, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centro Universitario UAEM Texcoco, Universidad Autonoma del Estado de Mexico, Av. Jardin Zumpango, s/n, Fraccionamiento El Tejocote, Texcoco, CP 56259, Estado de Mexico, Mexico. fgarcial@uaemex.mx","institution_ids":["https://openalex.org/I179647637","https://openalex.org/I31466659"]},{"raw_affiliation_string":"Centro Universitario UAEM Texcoco, Universidad Autonoma del Estado de Mexico, Av. Jardin Zumpango, s/n, Fraccionamiento El Tejocote, Texcoco, CP 56259, Estado de Mexico, Mexico","institution_ids":["https://openalex.org/I179647637"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065258336","display_name":"Asdr\u00fabal L\u00f3pez\u2010Chau","orcid":"https://orcid.org/0000-0001-5254-0939"},"institutions":[{"id":"https://openalex.org/I179647637","display_name":"Universidad Aut\u00f3noma del Estado de M\u00e9xico","ror":"https://ror.org/0079gpv38","country_code":"MX","type":"education","lineage":["https://openalex.org/I179647637"]}],"countries":["MX"],"is_corresponding":true,"raw_author_name":"Asdrubal Lopez-Chau","raw_affiliation_strings":["Centro Universitario UAEM Zumpango. Research Laboratory of Engineering and Applied Sciences, Universidad Autonoma del Estado de Mexico, Camino Viejo a Jilotzingo, continuacion Calle Rayon, Zumpango, CP 55600, Estado de Mexico, Mexico. alchau@uaemex.mx","Centro Universitario UAEM Zumpango. Research Laboratory of Engineering and Applied Sciences, Universidad Autonoma del Estado de Mexico, Camino Viejo a Jilotzingo, continuacion Calle Rayon, Zumpango, CP 55600, Estado de Mexico, Mexico"],"raw_orcid":"https://orcid.org/0000-0001-5254-0939","affiliations":[{"raw_affiliation_string":"Centro Universitario UAEM Zumpango. Research Laboratory of Engineering and Applied Sciences, Universidad Autonoma del Estado de Mexico, Camino Viejo a Jilotzingo, continuacion Calle Rayon, Zumpango, CP 55600, Estado de Mexico, Mexico. alchau@uaemex.mx","institution_ids":["https://openalex.org/I179647637"]},{"raw_affiliation_string":"Centro Universitario UAEM Zumpango. Research Laboratory of Engineering and Applied Sciences, Universidad Autonoma del Estado de Mexico, Camino Viejo a Jilotzingo, continuacion Calle Rayon, Zumpango, CP 55600, Estado de Mexico, Mexico","institution_ids":["https://openalex.org/I179647637"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048103294","display_name":"Jair Cervantes","orcid":"https://orcid.org/0000-0003-2012-8151"},"institutions":[{"id":"https://openalex.org/I179647637","display_name":"Universidad Aut\u00f3noma del Estado de M\u00e9xico","ror":"https://ror.org/0079gpv38","country_code":"MX","type":"education","lineage":["https://openalex.org/I179647637"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Jair Cervantes","raw_affiliation_strings":["Centro Universitario UAEM Texcoco, Universidad Autonoma del Estado de Mexico, Av. Jardin Zumpango, s/n, Fraccionamiento El Tejocote, Texcoco, CP 56259, Estado de Mexico, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centro Universitario UAEM Texcoco, Universidad Autonoma del Estado de Mexico, Av. Jardin Zumpango, s/n, Fraccionamiento El Tejocote, Texcoco, CP 56259, Estado de Mexico, Mexico","institution_ids":["https://openalex.org/I179647637"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103702193","display_name":"Sergio Ruiz","orcid":null},"institutions":[{"id":"https://openalex.org/I179647637","display_name":"Universidad Aut\u00f3noma del Estado de M\u00e9xico","ror":"https://ror.org/0079gpv38","country_code":"MX","type":"education","lineage":["https://openalex.org/I179647637"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Sergio Ruiz","raw_affiliation_strings":["Centro Universitario UAEM Texcoco, Universidad Autonoma del Estado de Mexico, Av. Jardin Zumpango, s/n, Fraccionamiento El Tejocote, Texcoco, CP 56259, Estado de Mexico, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centro Universitario UAEM Texcoco, Universidad Autonoma del Estado de Mexico, Av. Jardin Zumpango, s/n, Fraccionamiento El Tejocote, Texcoco, CP 56259, Estado de Mexico, Mexico","institution_ids":["https://openalex.org/I179647637"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5022867602","https://openalex.org/A5065258336"],"corresponding_institution_ids":["https://openalex.org/I179647637","https://openalex.org/I31466659"],"apc_list":{"value":3690,"currency":"USD","value_usd":3690},"apc_paid":null,"fwci":1.1356,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.76279607,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"62","issue":"8","first_page":"2371","last_page":"2388"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12874","display_name":"Digital Imaging for Blood Diseases","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12874","display_name":"Digital Imaging for Blood Diseases","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9915000200271606,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9725000262260437,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pixel","display_name":"Pixel","score":0.7672758102416992},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.7479763627052307},{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.7309094667434692},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6229365468025208},{"id":"https://openalex.org/keywords/hue","display_name":"Hue","score":0.6077806949615479},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.5818735361099243},{"id":"https://openalex.org/keywords/blob-detection","display_name":"Blob detection","score":0.5727701187133789},{"id":"https://openalex.org/keywords/image-segmentation","display_name":"Image segmentation","score":0.5615975856781006},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.5585741400718689},{"id":"https://openalex.org/keywords/pyramid","display_name":"Pyramid (geometry)","score":0.5571581125259399},{"id":"https://openalex.org/keywords/feature","display_name":"Feature (linguistics)","score":0.4695877134799957},{"id":"https://openalex.org/keywords/image-processing","display_name":"Image processing","score":0.34960365295410156},{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.3174985945224762},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.20827043056488037},{"id":"https://openalex.org/keywords/edge-detection","display_name":"Edge detection","score":0.12594860792160034}],"concepts":[{"id":"https://openalex.org/C160633673","wikidata":"https://www.wikidata.org/wiki/Q355198","display_name":"Pixel","level":2,"score":0.7672758102416992},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.7479763627052307},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.7309094667434692},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6229365468025208},{"id":"https://openalex.org/C126537357","wikidata":"https://www.wikidata.org/wiki/Q372948","display_name":"Hue","level":2,"score":0.6077806949615479},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.5818735361099243},{"id":"https://openalex.org/C29168087","wikidata":"https://www.wikidata.org/wiki/Q1026711","display_name":"Blob detection","level":5,"score":0.5727701187133789},{"id":"https://openalex.org/C124504099","wikidata":"https://www.wikidata.org/wiki/Q56933","display_name":"Image segmentation","level":3,"score":0.5615975856781006},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.5585741400718689},{"id":"https://openalex.org/C142575187","wikidata":"https://www.wikidata.org/wiki/Q3358290","display_name":"Pyramid (geometry)","level":2,"score":0.5571581125259399},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.4695877134799957},{"id":"https://openalex.org/C9417928","wikidata":"https://www.wikidata.org/wiki/Q1070689","display_name":"Image processing","level":3,"score":0.34960365295410156},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.3174985945224762},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.20827043056488037},{"id":"https://openalex.org/C193536780","wikidata":"https://www.wikidata.org/wiki/Q1513153","display_name":"Edge detection","level":4,"score":0.12594860792160034},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002467","descriptor_name":"Cell Nucleus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002467","descriptor_name":"Cell Nucleus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002467","descriptor_name":"Cell Nucleus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002467","descriptor_name":"Cell Nucleus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D007962","descriptor_name":"Leukocytes","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D007962","descriptor_name":"Leukocytes","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D007962","descriptor_name":"Leukocytes","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D007962","descriptor_name":"Leukocytes","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016011","descriptor_name":"Normal Distribution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016011","descriptor_name":"Normal Distribution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016011","descriptor_name":"Normal Distribution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016011","descriptor_name":"Normal Distribution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/s11517-024-03065-4","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11517-024-03065-4","pdf_url":null,"source":{"id":"https://openalex.org/S46300952","display_name":"Medical & Biological Engineering & Computing","issn_l":"0140-0118","issn":["0140-0118","1741-0444"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical & Biological Engineering & Computing","raw_type":"journal-article"},{"id":"pmid:38584206","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38584206","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical & biological engineering & computing","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W1791011331","https://openalex.org/W2103504761","https://openalex.org/W2546948708","https://openalex.org/W2767426931","https://openalex.org/W2778784312","https://openalex.org/W2792613771","https://openalex.org/W2800710461","https://openalex.org/W2811096586","https://openalex.org/W2890671308","https://openalex.org/W2911095970","https://openalex.org/W2921591511","https://openalex.org/W2944240340","https://openalex.org/W2963684193","https://openalex.org/W2981446550","https://openalex.org/W2989874578","https://openalex.org/W2990627807","https://openalex.org/W2998825217","https://openalex.org/W3001133036","https://openalex.org/W3004182657","https://openalex.org/W3006036315","https://openalex.org/W3008305517","https://openalex.org/W3037839692","https://openalex.org/W3061357073","https://openalex.org/W3091750992","https://openalex.org/W3105222690","https://openalex.org/W3115044335","https://openalex.org/W3119831909","https://openalex.org/W4205173843","https://openalex.org/W4220855143","https://openalex.org/W4229009185","https://openalex.org/W4285275205","https://openalex.org/W4285716232","https://openalex.org/W4286681668","https://openalex.org/W4313291109","https://openalex.org/W4324092840"],"related_works":["https://openalex.org/W4320518079","https://openalex.org/W2039822179","https://openalex.org/W4386771591","https://openalex.org/W2972873516","https://openalex.org/W2405125474","https://openalex.org/W2074864407","https://openalex.org/W2364223252","https://openalex.org/W1989502759","https://openalex.org/W2016044200","https://openalex.org/W2369716150"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":1}],"updated_date":"2026-07-29T09:40:50.615796","created_date":"2025-10-10T00:00:00"}