{"id":"https://openalex.org/W2928217699","doi":"https://doi.org/10.1007/s11517-019-01970-7","title":"Equivalent circuit models for a biomembrane impedance sensor and analysis of electrochemical impedance spectra based on support vector regression","display_name":"Equivalent circuit models for a biomembrane impedance sensor and analysis of electrochemical impedance spectra based on support vector regression","publication_year":2019,"publication_date":"2019-04-02","ids":{"openalex":"https://openalex.org/W2928217699","doi":"https://doi.org/10.1007/s11517-019-01970-7","mag":"2928217699"},"language":"en","primary_location":{"id":"doi:10.1007/s11517-019-01970-7","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s11517-019-01970-7","pdf_url":"https://link.springer.com/content/pdf/10.1007/s11517-019-01970-7.pdf","source":{"id":"https://openalex.org/S46300952","display_name":"Medical & Biological Engineering & Computing","issn_l":"0140-0118","issn":["0140-0118","1741-0444"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical & Biological Engineering & Computing","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://link.springer.com/content/pdf/10.1007/s11517-019-01970-7.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100755970","display_name":"Ying Xu","orcid":"https://orcid.org/0000-0003-4452-3180"},"institutions":[{"id":"https://openalex.org/I50760025","display_name":"Hangzhou Dianzi University","ror":"https://ror.org/0576gt767","country_code":"CN","type":"education","lineage":["https://openalex.org/I50760025"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Ying Xu","raw_affiliation_strings":["College of Life Information Science and Instrument Engineering, Hangzhou Dianzi University, No. 2 Road, Hangzhou, Zhejiang Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Life Information Science and Instrument Engineering, Hangzhou Dianzi University, No. 2 Road, Hangzhou, Zhejiang Province, China","institution_ids":["https://openalex.org/I50760025"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023505400","display_name":"Chao Li","orcid":"https://orcid.org/0000-0003-4783-1584"},"institutions":[{"id":"https://openalex.org/I50760025","display_name":"Hangzhou Dianzi University","ror":"https://ror.org/0576gt767","country_code":"CN","type":"education","lineage":["https://openalex.org/I50760025"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chao Li","raw_affiliation_strings":["College of Life Information Science and Instrument Engineering, Hangzhou Dianzi University, No. 2 Road, Hangzhou, Zhejiang Province, China"],"raw_orcid":"https://orcid.org/0000-0003-4783-1584","affiliations":[{"raw_affiliation_string":"College of Life Information Science and Instrument Engineering, Hangzhou Dianzi University, No. 2 Road, Hangzhou, Zhejiang Province, China","institution_ids":["https://openalex.org/I50760025"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052032442","display_name":"Wanxin Mei","orcid":null},"institutions":[{"id":"https://openalex.org/I50760025","display_name":"Hangzhou Dianzi University","ror":"https://ror.org/0576gt767","country_code":"CN","type":"education","lineage":["https://openalex.org/I50760025"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wanxin Mei","raw_affiliation_strings":["College of Life Information Science and Instrument Engineering, Hangzhou Dianzi University, No. 2 Road, Hangzhou, Zhejiang Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Life Information Science and Instrument Engineering, Hangzhou Dianzi University, No. 2 Road, Hangzhou, Zhejiang Province, China","institution_ids":["https://openalex.org/I50760025"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023478890","display_name":"Miao Guo","orcid":"https://orcid.org/0000-0001-7733-5077"},"institutions":[{"id":"https://openalex.org/I50760025","display_name":"Hangzhou Dianzi University","ror":"https://ror.org/0576gt767","country_code":"CN","type":"education","lineage":["https://openalex.org/I50760025"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Miao Guo","raw_affiliation_strings":["College of Life Information Science and Instrument Engineering, Hangzhou Dianzi University, No. 2 Road, Hangzhou, Zhejiang Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Life Information Science and Instrument Engineering, Hangzhou Dianzi University, No. 2 Road, Hangzhou, Zhejiang Province, China","institution_ids":["https://openalex.org/I50760025"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101754593","display_name":"Yong Yang","orcid":"https://orcid.org/0000-0001-6729-6086"},"institutions":[{"id":"https://openalex.org/I50760025","display_name":"Hangzhou Dianzi University","ror":"https://ror.org/0576gt767","country_code":"CN","type":"education","lineage":["https://openalex.org/I50760025"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yong Yang","raw_affiliation_strings":["College of Life Information Science and Instrument Engineering, Hangzhou Dianzi University, No. 2 Road, Hangzhou, Zhejiang Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Life Information Science and Instrument Engineering, Hangzhou Dianzi University, No. 2 Road, Hangzhou, Zhejiang Province, China","institution_ids":["https://openalex.org/I50760025"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5100755970"],"corresponding_institution_ids":["https://openalex.org/I50760025"],"apc_list":{"value":2890,"currency":"EUR","value_usd":3690},"apc_paid":{"value":2890,"currency":"EUR","value_usd":3690},"fwci":2.0393,"has_fulltext":true,"cited_by_count":27,"citation_normalized_percentile":{"value":0.84025241,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"57","issue":"7","first_page":"1515","last_page":"1524"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11472","display_name":"Analytical Chemistry and Sensors","score":0.9923999905586243,"subfield":{"id":"https://openalex.org/subfields/1502","display_name":"Bioengineering"},"field":{"id":"https://openalex.org/fields/15","display_name":"Chemical Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11472","display_name":"Analytical Chemistry and Sensors","score":0.9923999905586243,"subfield":{"id":"https://openalex.org/subfields/1502","display_name":"Bioengineering"},"field":{"id":"https://openalex.org/fields/15","display_name":"Chemical Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11667","display_name":"Advanced Chemical Sensor Technologies","score":0.9836999773979187,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10409","display_name":"Fuel Cells and Related Materials","score":0.9746000170707703,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/electrical-impedance","display_name":"Electrical impedance","score":0.6388596892356873},{"id":"https://openalex.org/keywords/human-physiology","display_name":"Human physiology","score":0.5205267667770386},{"id":"https://openalex.org/keywords/dielectric-spectroscopy","display_name":"Dielectric spectroscopy","score":0.5018296241760254},{"id":"https://openalex.org/keywords/regression-analysis","display_name":"Regression analysis","score":0.48578929901123047},{"id":"https://openalex.org/keywords/equivalent-circuit","display_name":"Equivalent circuit","score":0.47229626774787903},{"id":"https://openalex.org/keywords/support-vector-machine","display_name":"Support vector machine","score":0.45536771416664124},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.38553959131240845},{"id":"https://openalex.org/keywords/biological-system","display_name":"Biological system","score":0.3729596436023712},{"id":"https://openalex.org/keywords/electronic-engineering","display_name":"Electronic engineering","score":0.3710865378379822},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.35506483912467957},{"id":"https://openalex.org/keywords/analytical-chemistry","display_name":"Analytical Chemistry (journal)","score":0.3548733592033386},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.3303353190422058},{"id":"https://openalex.org/keywords/electrical-engineering","display_name":"Electrical engineering","score":0.26741915941238403},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.2397819459438324},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.23454275727272034},{"id":"https://openalex.org/keywords/electrochemistry","display_name":"Electrochemistry","score":0.2297441065311432},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.17870521545410156},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.1628342866897583},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.13254472613334656},{"id":"https://openalex.org/keywords/chromatography","display_name":"Chromatography","score":0.13206985592842102},{"id":"https://openalex.org/keywords/electrode","display_name":"Electrode","score":0.12036538124084473},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.11054962873458862},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.10785794258117676},{"id":"https://openalex.org/keywords/voltage","display_name":"Voltage","score":0.0804092288017273}],"concepts":[{"id":"https://openalex.org/C17829176","wikidata":"https://www.wikidata.org/wiki/Q179043","display_name":"Electrical impedance","level":2,"score":0.6388596892356873},{"id":"https://openalex.org/C2986265897","wikidata":"https://www.wikidata.org/wiki/Q23852","display_name":"Human physiology","level":2,"score":0.5205267667770386},{"id":"https://openalex.org/C7040849","wikidata":"https://www.wikidata.org/wiki/Q899580","display_name":"Dielectric spectroscopy","level":4,"score":0.5018296241760254},{"id":"https://openalex.org/C152877465","wikidata":"https://www.wikidata.org/wiki/Q208042","display_name":"Regression analysis","level":2,"score":0.48578929901123047},{"id":"https://openalex.org/C23572009","wikidata":"https://www.wikidata.org/wiki/Q964981","display_name":"Equivalent circuit","level":3,"score":0.47229626774787903},{"id":"https://openalex.org/C12267149","wikidata":"https://www.wikidata.org/wiki/Q282453","display_name":"Support vector machine","level":2,"score":0.45536771416664124},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.38553959131240845},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.3729596436023712},{"id":"https://openalex.org/C24326235","wikidata":"https://www.wikidata.org/wiki/Q126095","display_name":"Electronic engineering","level":1,"score":0.3710865378379822},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.35506483912467957},{"id":"https://openalex.org/C113196181","wikidata":"https://www.wikidata.org/wiki/Q485223","display_name":"Analytical Chemistry (journal)","level":2,"score":0.3548733592033386},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.3303353190422058},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.26741915941238403},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.2397819459438324},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.23454275727272034},{"id":"https://openalex.org/C52859227","wikidata":"https://www.wikidata.org/wiki/Q7877","display_name":"Electrochemistry","level":3,"score":0.2297441065311432},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.17870521545410156},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1628342866897583},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.13254472613334656},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.13206985592842102},{"id":"https://openalex.org/C17525397","wikidata":"https://www.wikidata.org/wiki/Q176140","display_name":"Electrode","level":2,"score":0.12036538124084473},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.11054962873458862},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.10785794258117676},{"id":"https://openalex.org/C165801399","wikidata":"https://www.wikidata.org/wiki/Q25428","display_name":"Voltage","level":2,"score":0.0804092288017273},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1007/s11517-019-01970-7","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s11517-019-01970-7","pdf_url":"https://link.springer.com/content/pdf/10.1007/s11517-019-01970-7.pdf","source":{"id":"https://openalex.org/S46300952","display_name":"Medical & Biological Engineering & Computing","issn_l":"0140-0118","issn":["0140-0118","1741-0444"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical & Biological Engineering & Computing","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6592963","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6592963","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Med Biol Eng Comput","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1007/s11517-019-01970-7","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s11517-019-01970-7","pdf_url":"https://link.springer.com/content/pdf/10.1007/s11517-019-01970-7.pdf","source":{"id":"https://openalex.org/S46300952","display_name":"Medical & Biological Engineering & Computing","issn_l":"0140-0118","issn":["0140-0118","1741-0444"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical & Biological Engineering & Computing","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/7","score":0.4000000059604645,"display_name":"Affordable and clean energy"}],"awards":[{"id":"https://openalex.org/G3660849800","display_name":null,"funder_award_id":"61871165","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2928217699.pdf","grobid_xml":"https://content.openalex.org/works/W2928217699.grobid-xml"},"referenced_works_count":34,"referenced_works":["https://openalex.org/W1583283746","https://openalex.org/W1965797481","https://openalex.org/W1976975339","https://openalex.org/W1982803976","https://openalex.org/W1985001284","https://openalex.org/W1986345492","https://openalex.org/W1989285017","https://openalex.org/W1993398175","https://openalex.org/W2002971039","https://openalex.org/W2003166240","https://openalex.org/W2012432664","https://openalex.org/W2017165023","https://openalex.org/W2025884294","https://openalex.org/W2030078037","https://openalex.org/W2031489288","https://openalex.org/W2046334142","https://openalex.org/W2047811690","https://openalex.org/W2060605943","https://openalex.org/W2071045149","https://openalex.org/W2075811533","https://openalex.org/W2078102637","https://openalex.org/W2080213825","https://openalex.org/W2083266351","https://openalex.org/W2102213552","https://openalex.org/W2122143506","https://openalex.org/W2163877626","https://openalex.org/W2215415349","https://openalex.org/W2313366011","https://openalex.org/W2521442358","https://openalex.org/W2754731956","https://openalex.org/W2766305410","https://openalex.org/W2964340629","https://openalex.org/W4254453738","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2568003367","https://openalex.org/W4382021005","https://openalex.org/W2068623945","https://openalex.org/W2896568827","https://openalex.org/W4243773385","https://openalex.org/W4206569389","https://openalex.org/W2050511751","https://openalex.org/W3202183310","https://openalex.org/W2117283676","https://openalex.org/W2393144863"],"abstract_inverted_index":{"In":[0],"this":[1],"study,":[2],"an":[3,53],"electrochemical":[4],"impedance":[5,24,48,69],"biosensor":[6],"was":[7],"developed":[8],"as":[9],"a":[10,98,116],"simple":[11],"and":[12,50,59,90,113],"fast":[13],"method":[14],"for":[15,56,64],"real-time":[16],"monitoring":[17],"of":[18,77,92,101,108,119],"biofilm":[19],"binding":[20,74],"properties":[21],"via":[22],"continuous":[23],"spectroscopy.":[25],"To":[26],"prepare":[27],"the":[28,47,73,82,88,105],"sensing":[29],"membrane,":[30],"cells":[31,78],"were":[32,44],"immobilized":[33],"onto":[34],"gold":[35],"electrodes":[36],"with":[37,46,97,115],"nitrocellulose":[38],"membranes.":[39],"Different":[40],"cell":[41,83],"growth":[42],"features":[43],"measured":[45],"instrument":[49],"analyzed":[51],"using":[52],"equivalent":[54],"model":[55],"data":[57,65,102],"fitting":[58],"support":[60],"vector":[61],"regression":[62],"(SVR)":[63],"processing.":[66],"The":[67],"collected":[68],"spectra":[70],"revealed":[71],"that":[72],"attachment":[75],"areas":[76],"differ":[79],"depending":[80],"on":[81],"density.":[84],"Our":[85],"results":[86],"demonstrate":[87],"usefulness":[89],"feasibility":[91],"training":[93],"our":[94],"impedance-based":[95],"sensor":[96],"small":[99],"amount":[100],"to":[103],"predict":[104],"effective":[106],"area":[107],"different":[109],"biofilms":[110],"(GE,":[111],"NGE,":[112],"CNGE),":[114],"prediction":[117],"error":[118],"9.8%.":[120]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":7},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":5}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2019-04-11T00:00:00"}