{"id":"https://openalex.org/W2034055544","doi":"https://doi.org/10.1007/s11517-011-0807-2","title":"Differential remodeling responses of cerebral and skeletal muscle arterioles in a novel organ culture system","display_name":"Differential remodeling responses of cerebral and skeletal muscle arterioles in a novel organ culture system","publication_year":2011,"publication_date":"2011-07-22","ids":{"openalex":"https://openalex.org/W2034055544","doi":"https://doi.org/10.1007/s11517-011-0807-2","mag":"2034055544","pmid":"https://pubmed.ncbi.nlm.nih.gov/21786016"},"language":"en","primary_location":{"id":"doi:10.1007/s11517-011-0807-2","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11517-011-0807-2","pdf_url":null,"source":{"id":"https://openalex.org/S46300952","display_name":"Medical & Biological Engineering & Computing","issn_l":"0140-0118","issn":["0140-0118","1741-0444"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical & Biological Engineering & Computing","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3516281","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047867470","display_name":"Samantha M. Steelman","orcid":null},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Samantha M. Steelman","raw_affiliation_strings":["Department of Veterinary Integrative Biosciences, Texas A&M University, College Station, College Station, TX 77843-4458, USA. ssteelman@cvm.tamu.edu","Department of Veterinary Integrative Biosciences, Texas A&M University, College Station, College Station, USA"],"affiliations":[{"raw_affiliation_string":"Department of Veterinary Integrative Biosciences, Texas A&M University, College Station, College Station, TX 77843-4458, USA. ssteelman@cvm.tamu.edu","institution_ids":["https://openalex.org/I91045830"]},{"raw_affiliation_string":"Department of Veterinary Integrative Biosciences, Texas A&M University, College Station, College Station, USA","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5014180482","display_name":"Jay D. Humphrey","orcid":"https://orcid.org/0000-0003-1011-2025"},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jay D. Humphrey","raw_affiliation_strings":["Department of Biomedical Engineering, Yale University, New Haven, CT, 06511-8962, USA","Department of Biomedical Engineering, Yale University, New Haven, USA"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Yale University, New Haven, CT, 06511-8962, USA","institution_ids":["https://openalex.org/I32971472"]},{"raw_affiliation_string":"Department of Biomedical Engineering, Yale University, New Haven, USA","institution_ids":["https://openalex.org/I32971472"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5047867470"],"corresponding_institution_ids":["https://openalex.org/I91045830"],"apc_list":{"value":2890,"currency":"EUR","value_usd":3690},"apc_paid":null,"fwci":0.7481,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.72725843,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":96},"biblio":{"volume":"49","issue":"9","first_page":"1015","last_page":"1023"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10706","display_name":"Traumatic Brain Injury and Neurovascular Disturbances","score":0.9952999949455261,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10706","display_name":"Traumatic Brain Injury and Neurovascular Disturbances","score":0.9952999949455261,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.9929999709129333,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12067","display_name":"Renal and Vascular Pathologies","score":0.9907000064849854,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/myograph","display_name":"Myograph","score":0.7388910055160522},{"id":"https://openalex.org/keywords/microcirculation","display_name":"Microcirculation","score":0.7230175733566284},{"id":"https://openalex.org/keywords/skeletal-muscle","display_name":"Skeletal muscle","score":0.6656947731971741},{"id":"https://openalex.org/keywords/organ-culture","display_name":"Organ culture","score":0.631371021270752},{"id":"https://openalex.org/keywords/arteriole","display_name":"Arteriole","score":0.620283842086792},{"id":"https://openalex.org/keywords/myogenic-contraction","display_name":"Myogenic contraction","score":0.5277519822120667},{"id":"https://openalex.org/keywords/contractility","display_name":"Contractility","score":0.5026051998138428},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.49012431502342224},{"id":"https://openalex.org/keywords/cerebral-circulation","display_name":"Cerebral circulation","score":0.4642733931541443},{"id":"https://openalex.org/keywords/anatomy","display_name":"Anatomy","score":0.43270143866539},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.38907697796821594},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.3486003279685974},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.3444785475730896},{"id":"https://openalex.org/keywords/endocrinology","display_name":"Endocrinology","score":0.3440271019935608},{"id":"https://openalex.org/keywords/endothelium","display_name":"Endothelium","score":0.15698254108428955},{"id":"https://openalex.org/keywords/in-vitro","display_name":"In vitro","score":0.09725683927536011},{"id":"https://openalex.org/keywords/smooth-muscle","display_name":"Smooth muscle","score":0.07757139205932617}],"concepts":[{"id":"https://openalex.org/C2779941686","wikidata":"https://www.wikidata.org/wiki/Q6947930","display_name":"Myograph","level":3,"score":0.7388910055160522},{"id":"https://openalex.org/C12722491","wikidata":"https://www.wikidata.org/wiki/Q1632335","display_name":"Microcirculation","level":2,"score":0.7230175733566284},{"id":"https://openalex.org/C2779959927","wikidata":"https://www.wikidata.org/wiki/Q1048687","display_name":"Skeletal muscle","level":2,"score":0.6656947731971741},{"id":"https://openalex.org/C28483552","wikidata":"https://www.wikidata.org/wiki/Q3634161","display_name":"Organ culture","level":3,"score":0.631371021270752},{"id":"https://openalex.org/C2779482390","wikidata":"https://www.wikidata.org/wiki/Q501908","display_name":"Arteriole","level":3,"score":0.620283842086792},{"id":"https://openalex.org/C58336856","wikidata":"https://www.wikidata.org/wiki/Q6947924","display_name":"Myogenic contraction","level":3,"score":0.5277519822120667},{"id":"https://openalex.org/C39133596","wikidata":"https://www.wikidata.org/wiki/Q5165683","display_name":"Contractility","level":2,"score":0.5026051998138428},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.49012431502342224},{"id":"https://openalex.org/C119671327","wikidata":"https://www.wikidata.org/wiki/Q886843","display_name":"Cerebral circulation","level":2,"score":0.4642733931541443},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.43270143866539},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.38907697796821594},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3486003279685974},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3444785475730896},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3440271019935608},{"id":"https://openalex.org/C2776992346","wikidata":"https://www.wikidata.org/wiki/Q111140","display_name":"Endothelium","level":2,"score":0.15698254108428955},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.09725683927536011},{"id":"https://openalex.org/C2992686903","wikidata":"https://www.wikidata.org/wiki/Q208453","display_name":"Smooth muscle","level":2,"score":0.07757139205932617},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001160","descriptor_name":"Arterioles","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001160","descriptor_name":"Arterioles","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001160","descriptor_name":"Arterioles","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D002560","descriptor_name":"Cerebrovascular Circulation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002560","descriptor_name":"Cerebrovascular Circulation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002560","descriptor_name":"Cerebrovascular Circulation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008833","descriptor_name":"Microcirculation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008833","descriptor_name":"Microcirculation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008833","descriptor_name":"Microcirculation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009924","descriptor_name":"Organ Culture Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D009924","descriptor_name":"Organ Culture Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D009924","descriptor_name":"Organ Culture Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D011817","descriptor_name":"Rabbits","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011817","descriptor_name":"Rabbits","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011817","descriptor_name":"Rabbits","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D044967","descriptor_name":"Serum","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044967","descriptor_name":"Serum","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044967","descriptor_name":"Serum","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1007/s11517-011-0807-2","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11517-011-0807-2","pdf_url":null,"source":{"id":"https://openalex.org/S46300952","display_name":"Medical & Biological Engineering & Computing","issn_l":"0140-0118","issn":["0140-0118","1741-0444"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical & Biological Engineering & Computing","raw_type":"journal-article"},{"id":"pmid:21786016","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21786016","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical & biological engineering & computing","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:3516281","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3516281","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Med Biol Eng Comput","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:3516281","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3516281","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Med Biol Eng Comput","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.5899999737739563}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W1922862879","https://openalex.org/W1968637250","https://openalex.org/W1970754132","https://openalex.org/W1994591006","https://openalex.org/W2009372345","https://openalex.org/W2012180376","https://openalex.org/W2016672488","https://openalex.org/W2027375644","https://openalex.org/W2029796239","https://openalex.org/W2033179718","https://openalex.org/W2033568427","https://openalex.org/W2035645006","https://openalex.org/W2058597788","https://openalex.org/W2066190048","https://openalex.org/W2074016229","https://openalex.org/W2078954448","https://openalex.org/W2093984243","https://openalex.org/W2103657521","https://openalex.org/W2104824409","https://openalex.org/W2105352292","https://openalex.org/W2111472663","https://openalex.org/W2119534555","https://openalex.org/W2125669395","https://openalex.org/W2130806322","https://openalex.org/W2138021047","https://openalex.org/W2141081410","https://openalex.org/W2146155590","https://openalex.org/W2149619346","https://openalex.org/W2159070858","https://openalex.org/W2168147238","https://openalex.org/W2173200376","https://openalex.org/W2274833912","https://openalex.org/W2382870241","https://openalex.org/W2411251172","https://openalex.org/W2412491183"],"related_works":["https://openalex.org/W2389280935","https://openalex.org/W3148548002","https://openalex.org/W2193897216","https://openalex.org/W2077132138","https://openalex.org/W2107290312","https://openalex.org/W2276737872","https://openalex.org/W2020535239","https://openalex.org/W1989565744","https://openalex.org/W1901307347","https://openalex.org/W1591248362"],"abstract_inverted_index":null,"counts_by_year":[{"year":2014,"cited_by_count":2},{"year":2012,"cited_by_count":2}],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2025-10-10T00:00:00"}