{"id":"https://openalex.org/W4411527607","doi":"https://doi.org/10.1007/s11432-024-4461-0","title":"AI in drug development: advances in response, combination therapy, repositioning, and molecular design","display_name":"AI in drug development: advances in response, combination therapy, repositioning, and molecular design","publication_year":2025,"publication_date":"2025-06-19","ids":{"openalex":"https://openalex.org/W4411527607","doi":"https://doi.org/10.1007/s11432-024-4461-0"},"language":"en","primary_location":{"id":"doi:10.1007/s11432-024-4461-0","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11432-024-4461-0","pdf_url":null,"source":{"id":"https://openalex.org/S4210218743","display_name":"Science China Information Sciences","issn_l":"1674-733X","issn":["1674-733X","1869-1919"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Science China Information Sciences","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5021455957","display_name":"Ren Qi","orcid":"https://orcid.org/0000-0003-0341-4818"},"institutions":[{"id":"https://openalex.org/I125839683","display_name":"Beijing Institute of Technology","ror":"https://ror.org/01skt4w74","country_code":"CN","type":"education","lineage":["https://openalex.org/I125839683","https://openalex.org/I890469752"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ren Qi","raw_affiliation_strings":["School of Computer Science and Technology, Beijing Institute of Technology, Beijing, 100081, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computer Science and Technology, Beijing Institute of Technology, Beijing, 100081, China","institution_ids":["https://openalex.org/I125839683"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086294465","display_name":"Shujia Liu","orcid":null},"institutions":[{"id":"https://openalex.org/I125839683","display_name":"Beijing Institute of Technology","ror":"https://ror.org/01skt4w74","country_code":"CN","type":"education","lineage":["https://openalex.org/I125839683","https://openalex.org/I890469752"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shujia Liu","raw_affiliation_strings":["School of Computer Science and Technology, Beijing Institute of Technology, Beijing, 100081, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computer Science and Technology, Beijing Institute of Technology, Beijing, 100081, China","institution_ids":["https://openalex.org/I125839683"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114177388","display_name":"Xingqi Hui","orcid":null},"institutions":[{"id":"https://openalex.org/I125839683","display_name":"Beijing Institute of Technology","ror":"https://ror.org/01skt4w74","country_code":"CN","type":"education","lineage":["https://openalex.org/I125839683","https://openalex.org/I890469752"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xingqi Hui","raw_affiliation_strings":["School of Computer Science and Technology, Beijing Institute of Technology, Beijing, 100081, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computer Science and Technology, Beijing Institute of Technology, Beijing, 100081, China","institution_ids":["https://openalex.org/I125839683"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055156384","display_name":"Alexey \u041a. Shaytan","orcid":"https://orcid.org/0000-0003-0312-938X"},"institutions":[{"id":"https://openalex.org/I118501908","display_name":"National Research University Higher School of Economics","ror":"https://ror.org/055f7t516","country_code":"RU","type":"education","lineage":["https://openalex.org/I118501908"]},{"id":"https://openalex.org/I19880235","display_name":"Lomonosov Moscow State University","ror":"https://ror.org/010pmpe69","country_code":"RU","type":"education","lineage":["https://openalex.org/I19880235"]},{"id":"https://openalex.org/I278361347","display_name":"International University in Moscow","ror":"https://ror.org/01bkha031","country_code":"RU","type":"education","lineage":["https://openalex.org/I278361347"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Alexey K. Shaytan","raw_affiliation_strings":["Department of Biology, Lomonosov Moscow State University, Moscow, 119234, Russia","International Laboratory of Bioinformatics, AI and Digital Sciences Institute, Faculty of Computer Science, HSE University, Moscow, 109028, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Lomonosov Moscow State University, Moscow, 119234, Russia","institution_ids":["https://openalex.org/I19880235"]},{"raw_affiliation_string":"International Laboratory of Bioinformatics, AI and Digital Sciences Institute, Faculty of Computer Science, HSE University, Moscow, 109028, Russia","institution_ids":["https://openalex.org/I118501908","https://openalex.org/I278361347"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5115587971","display_name":"Bin Liu","orcid":"https://orcid.org/0000-0001-5381-3644"},"institutions":[{"id":"https://openalex.org/I125839683","display_name":"Beijing Institute of Technology","ror":"https://ror.org/01skt4w74","country_code":"CN","type":"education","lineage":["https://openalex.org/I125839683","https://openalex.org/I890469752"]},{"id":"https://openalex.org/I180726961","display_name":"Shenzhen University","ror":"https://ror.org/01vy4gh70","country_code":"CN","type":"education","lineage":["https://openalex.org/I180726961"]},{"id":"https://openalex.org/I4210086710","display_name":"Beijing Academy of Social Sciences","ror":"https://ror.org/003ayef58","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210086710"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Bin Liu","raw_affiliation_strings":["SMBU-MSU-BIT Joint Laboratory on Bioinformatics and Engineering Biology, Shenzhen MSU-BIT University, Shenzhen, 518172, China","School of Computer Science and Technology, Beijing Institute of Technology, Beijing, 100081, China","Zhongguancun Academy, Beijing, 100094, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"SMBU-MSU-BIT Joint Laboratory on Bioinformatics and Engineering Biology, Shenzhen MSU-BIT University, Shenzhen, 518172, China","institution_ids":["https://openalex.org/I180726961"]},{"raw_affiliation_string":"School of Computer Science and Technology, Beijing Institute of Technology, Beijing, 100081, China","institution_ids":["https://openalex.org/I125839683"]},{"raw_affiliation_string":"Zhongguancun Academy, Beijing, 100094, China","institution_ids":["https://openalex.org/I4210086710"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5115587971"],"corresponding_institution_ids":["https://openalex.org/I125839683","https://openalex.org/I180726961","https://openalex.org/I4210086710"],"apc_list":{"value":2990,"currency":"USD","value_usd":2990},"apc_paid":null,"fwci":11.5816,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.98683378,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"68","issue":"7","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11948","display_name":"Machine Learning in Materials Science","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9496999979019165,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/drug-development","display_name":"Drug development","score":0.5450291633605957},{"id":"https://openalex.org/keywords/drug-repositioning","display_name":"Drug repositioning","score":0.5369513034820557},{"id":"https://openalex.org/keywords/drug","display_name":"Drug","score":0.5292132496833801},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.3752285838127136},{"id":"https://openalex.org/keywords/pharmacology","display_name":"Pharmacology","score":0.29585060477256775}],"concepts":[{"id":"https://openalex.org/C64903051","wikidata":"https://www.wikidata.org/wiki/Q2198549","display_name":"Drug development","level":3,"score":0.5450291633605957},{"id":"https://openalex.org/C103637391","wikidata":"https://www.wikidata.org/wiki/Q5308921","display_name":"Drug repositioning","level":3,"score":0.5369513034820557},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.5292132496833801},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3752285838127136},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.29585060477256775}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/s11432-024-4461-0","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11432-024-4461-0","pdf_url":null,"source":{"id":"https://openalex.org/S4210218743","display_name":"Science China Information Sciences","issn_l":"1674-733X","issn":["1674-733X","1869-1919"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Science China Information Sciences","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":138,"referenced_works":["https://openalex.org/W1975147762","https://openalex.org/W2029980980","https://openalex.org/W2043398720","https://openalex.org/W2064675550","https://openalex.org/W2108068107","https://openalex.org/W2116341502","https://openalex.org/W2136661588","https://openalex.org/W2145877930","https://openalex.org/W2151357092","https://openalex.org/W2158485828","https://openalex.org/W2575228167","https://openalex.org/W2605810679","https://openalex.org/W2765811365","https://openalex.org/W2767891136","https://openalex.org/W2790203313","https://openalex.org/W2901411193","https://openalex.org/W2914304175","https://openalex.org/W2915130814","https://openalex.org/W2942883778","https://openalex.org/W2946099214","https://openalex.org/W2950182476","https://openalex.org/W2955502047","https://openalex.org/W2965311404","https://openalex.org/W2971275989","https://openalex.org/W2981135546","https://openalex.org/W2992974753","https://openalex.org/W3000469142","https://openalex.org/W3000982932","https://openalex.org/W3005505802","https://openalex.org/W3007309629","https://openalex.org/W3010960510","https://openalex.org/W3022395336","https://openalex.org/W3035604179","https://openalex.org/W3037826474","https://openalex.org/W3042826782","https://openalex.org/W3042995081","https://openalex.org/W3086078626","https://openalex.org/W3093030756","https://openalex.org/W3100789280","https://openalex.org/W3107514561","https://openalex.org/W3107587236","https://openalex.org/W3116278528","https://openalex.org/W3127930610","https://openalex.org/W3130727496","https://openalex.org/W3138833245","https://openalex.org/W3148071990","https://openalex.org/W3162323249","https://openalex.org/W3167619859","https://openalex.org/W3168741823","https://openalex.org/W3173875945","https://openalex.org/W3177828909","https://openalex.org/W3192134500","https://openalex.org/W3195161349","https://openalex.org/W3195848388","https://openalex.org/W3203908308","https://openalex.org/W3209056694","https://openalex.org/W3209416355","https://openalex.org/W3209882608","https://openalex.org/W3211795435","https://openalex.org/W3216616254","https://openalex.org/W4206078729","https://openalex.org/W4206547282","https://openalex.org/W4212815277","https://openalex.org/W4214831389","https://openalex.org/W4220798957","https://openalex.org/W4229447215","https://openalex.org/W4289315841","https://openalex.org/W4297179162","https://openalex.org/W4306361925","https://openalex.org/W4307135222","https://openalex.org/W4307952312","https://openalex.org/W4308834336","https://openalex.org/W4310642160","https://openalex.org/W4311247426","https://openalex.org/W4312099026","https://openalex.org/W4312114892","https://openalex.org/W4313703391","https://openalex.org/W4316035372","https://openalex.org/W4327676467","https://openalex.org/W4328048216","https://openalex.org/W4361222431","https://openalex.org/W4362709188","https://openalex.org/W4381149253","https://openalex.org/W4382631779","https://openalex.org/W4383912288","https://openalex.org/W4384700321","https://openalex.org/W4384818885","https://openalex.org/W4385958045","https://openalex.org/W4386046819","https://openalex.org/W4387033830","https://openalex.org/W4387237425","https://openalex.org/W4387401786","https://openalex.org/W4388464545","https://openalex.org/W4389049275","https://openalex.org/W4389525220","https://openalex.org/W4389639908","https://openalex.org/W4390946589","https://openalex.org/W4391610180","https://openalex.org/W4391782448","https://openalex.org/W4391927204","https://openalex.org/W4391982099","https://openalex.org/W4392163954","https://openalex.org/W4392284238","https://openalex.org/W4392302842","https://openalex.org/W4393181728","https://openalex.org/W4393222489","https://openalex.org/W4393377829","https://openalex.org/W4394582099","https://openalex.org/W4394994059","https://openalex.org/W4396660597","https://openalex.org/W4396721167","https://openalex.org/W4396740393","https://openalex.org/W4399369411","https://openalex.org/W4399992705","https://openalex.org/W4400061043","https://openalex.org/W4400447855","https://openalex.org/W4400876473","https://openalex.org/W4401503596","https://openalex.org/W4401760234","https://openalex.org/W4401801484","https://openalex.org/W4401918320","https://openalex.org/W4402322935","https://openalex.org/W4402827768","https://openalex.org/W4402900312","https://openalex.org/W4403722347","https://openalex.org/W4403782367","https://openalex.org/W4403782504","https://openalex.org/W4403784877","https://openalex.org/W4403889214","https://openalex.org/W4403891981","https://openalex.org/W4404167537","https://openalex.org/W4404181791","https://openalex.org/W4404386116","https://openalex.org/W4404650713","https://openalex.org/W4405425991","https://openalex.org/W6739901393","https://openalex.org/W6803334427","https://openalex.org/W7064894329"],"related_works":["https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W3031052312","https://openalex.org/W2399140686","https://openalex.org/W1980001478","https://openalex.org/W3166711969","https://openalex.org/W3175975129","https://openalex.org/W4387302591","https://openalex.org/W4291511859","https://openalex.org/W1585256759"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":12},{"year":2025,"cited_by_count":3}],"updated_date":"2026-07-23T08:03:31.855105","created_date":"2025-10-10T00:00:00"}
