{"id":"https://openalex.org/W2087384675","doi":"https://doi.org/10.1007/s11424-010-0209-9","title":"The effect of coupled feedback on noise filtering in signal transduction networks","display_name":"The effect of coupled feedback on noise filtering in signal transduction networks","publication_year":2010,"publication_date":"2010-10-01","ids":{"openalex":"https://openalex.org/W2087384675","doi":"https://doi.org/10.1007/s11424-010-0209-9","mag":"2087384675"},"language":"en","primary_location":{"id":"doi:10.1007/s11424-010-0209-9","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11424-010-0209-9","pdf_url":null,"source":{"id":"https://openalex.org/S45848134","display_name":"Journal of Systems Science and Complexity","issn_l":"1009-6124","issn":["1009-6124","1559-7067"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Systems Science and Complexity","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101994300","display_name":"Dengyu Liu","orcid":"https://orcid.org/0000-0002-8245-9573"},"institutions":[{"id":"https://openalex.org/I113940042","display_name":"Shanghai University","ror":"https://ror.org/006teas31","country_code":"CN","type":"education","lineage":["https://openalex.org/I113940042"]},{"id":"https://openalex.org/I14748160","display_name":"Jinggangshan University","ror":"https://ror.org/04exd0a76","country_code":"CN","type":"education","lineage":["https://openalex.org/I14748160"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dengyu Liu","raw_affiliation_strings":["College of Physics and Mathematics, Jinggangshan University, Ji\u2019an, 343009, China","Institute of Systems Biology, Shanghai University, Shanghai, 200444, China","Jinggangshan University","Shanghai University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Physics and Mathematics, Jinggangshan University, Ji\u2019an, 343009, China","institution_ids":["https://openalex.org/I14748160"]},{"raw_affiliation_string":"Institute of Systems Biology, Shanghai University, Shanghai, 200444, China","institution_ids":["https://openalex.org/I113940042"]},{"raw_affiliation_string":"Jinggangshan University","institution_ids":["https://openalex.org/I14748160"]},{"raw_affiliation_string":"Shanghai University","institution_ids":["https://openalex.org/I113940042"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032354393","display_name":"Xiao Chang","orcid":"https://orcid.org/0000-0002-0230-0416"},"institutions":[{"id":"https://openalex.org/I113940042","display_name":"Shanghai University","ror":"https://ror.org/006teas31","country_code":"CN","type":"education","lineage":["https://openalex.org/I113940042"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiao Chang","raw_affiliation_strings":["Institute of Systems Biology, Shanghai University, Shanghai, 200444, China","Institute of Systems Biology, Shanghai University, Shanghai\u00a0, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Systems Biology, Shanghai University, Shanghai, 200444, China","institution_ids":["https://openalex.org/I113940042"]},{"raw_affiliation_string":"Institute of Systems Biology, Shanghai University, Shanghai\u00a0, China","institution_ids":["https://openalex.org/I113940042"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112107398","display_name":"Zengrong Liu","orcid":null},"institutions":[{"id":"https://openalex.org/I113940042","display_name":"Shanghai University","ror":"https://ror.org/006teas31","country_code":"CN","type":"education","lineage":["https://openalex.org/I113940042"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zengrong Liu","raw_affiliation_strings":["Institute of Systems Biology, Shanghai University, Shanghai, 200444, China","Institute of Systems Biology, Shanghai University, Shanghai\u00a0, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Systems Biology, Shanghai University, Shanghai, 200444, China","institution_ids":["https://openalex.org/I113940042"]},{"raw_affiliation_string":"Institute of Systems Biology, Shanghai University, Shanghai\u00a0, China","institution_ids":["https://openalex.org/I113940042"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012283696","display_name":"Luonan Chen","orcid":"https://orcid.org/0000-0002-3960-0068"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210106477","display_name":"Shanghai Institutes for Biological Sciences","ror":"https://ror.org/011rf9d86","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210106477"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Luonan Chen","raw_affiliation_strings":["Key Laboratory of Systems Biology, SIBS-Novo Nordisk Translational Research Centre for PreDiabetes, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, 200031, China","Key Laboratory of Systems Biology, SIBS-Novo Nordisk Translational Research Centre for PreDiabetes, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Systems Biology, SIBS-Novo Nordisk Translational Research Centre for PreDiabetes, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, 200031, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210106477"]},{"raw_affiliation_string":"Key Laboratory of Systems Biology, SIBS-Novo Nordisk Translational Research Centre for PreDiabetes, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210106477"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100387932","display_name":"Ruiqi Wang","orcid":"https://orcid.org/0000-0001-6369-6162"},"institutions":[{"id":"https://openalex.org/I113940042","display_name":"Shanghai University","ror":"https://ror.org/006teas31","country_code":"CN","type":"education","lineage":["https://openalex.org/I113940042"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Ruiqi Wang","raw_affiliation_strings":["Institute of Systems Biology, Shanghai University, Shanghai, 200444, China","Institute of Systems Biology, Shanghai University, Shanghai\u00a0, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Systems Biology, Shanghai University, Shanghai, 200444, China","institution_ids":["https://openalex.org/I113940042"]},{"raw_affiliation_string":"Institute of Systems Biology, Shanghai University, Shanghai\u00a0, China","institution_ids":["https://openalex.org/I113940042"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5100387932"],"corresponding_institution_ids":["https://openalex.org/I113940042"],"apc_list":{"value":2890,"currency":"USD","value_usd":2890},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.11193329,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"23","issue":"5","first_page":"942","last_page":"950"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12813","display_name":"Plant and Biological Electrophysiology Studies","score":0.974399983882904,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13539","display_name":"thermodynamics and calorimetric analyses","score":0.9710999727249146,"subfield":{"id":"https://openalex.org/subfields/1606","display_name":"Physical and Theoretical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/filter","display_name":"Filter (signal processing)","score":0.6837722063064575},{"id":"https://openalex.org/keywords/noise","display_name":"Noise (video)","score":0.6547834873199463},{"id":"https://openalex.org/keywords/negative-feedback","display_name":"Negative feedback","score":0.5967377424240112},{"id":"https://openalex.org/keywords/coupling","display_name":"Coupling (piping)","score":0.5870699286460876},{"id":"https://openalex.org/keywords/signal","display_name":"SIGNAL (programming language)","score":0.566541314125061},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5390045642852783},{"id":"https://openalex.org/keywords/positive-feedback","display_name":"Positive feedback","score":0.513692319393158},{"id":"https://openalex.org/keywords/control-theory","display_name":"Control theory (sociology)","score":0.46722257137298584},{"id":"https://openalex.org/keywords/process","display_name":"Process (computing)","score":0.4569043219089508},{"id":"https://openalex.org/keywords/biological-system","display_name":"Biological system","score":0.38484013080596924},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.2941632866859436},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.1480647623538971},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.11348947882652283},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.10076904296875}],"concepts":[{"id":"https://openalex.org/C106131492","wikidata":"https://www.wikidata.org/wiki/Q3072260","display_name":"Filter (signal processing)","level":2,"score":0.6837722063064575},{"id":"https://openalex.org/C99498987","wikidata":"https://www.wikidata.org/wiki/Q2210247","display_name":"Noise (video)","level":3,"score":0.6547834873199463},{"id":"https://openalex.org/C93586867","wikidata":"https://www.wikidata.org/wiki/Q62527","display_name":"Negative feedback","level":3,"score":0.5967377424240112},{"id":"https://openalex.org/C131584629","wikidata":"https://www.wikidata.org/wiki/Q4308705","display_name":"Coupling (piping)","level":2,"score":0.5870699286460876},{"id":"https://openalex.org/C2779843651","wikidata":"https://www.wikidata.org/wiki/Q7390335","display_name":"SIGNAL (programming language)","level":2,"score":0.566541314125061},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5390045642852783},{"id":"https://openalex.org/C48207687","wikidata":"https://www.wikidata.org/wiki/Q918004","display_name":"Positive feedback","level":2,"score":0.513692319393158},{"id":"https://openalex.org/C47446073","wikidata":"https://www.wikidata.org/wiki/Q5165890","display_name":"Control theory (sociology)","level":3,"score":0.46722257137298584},{"id":"https://openalex.org/C98045186","wikidata":"https://www.wikidata.org/wiki/Q205663","display_name":"Process (computing)","level":2,"score":0.4569043219089508},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.38484013080596924},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.2941632866859436},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.1480647623538971},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.11348947882652283},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.10076904296875},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.0},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.0},{"id":"https://openalex.org/C165801399","wikidata":"https://www.wikidata.org/wiki/Q25428","display_name":"Voltage","level":2,"score":0.0},{"id":"https://openalex.org/C2775924081","wikidata":"https://www.wikidata.org/wiki/Q55608371","display_name":"Control (management)","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/s11424-010-0209-9","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11424-010-0209-9","pdf_url":null,"source":{"id":"https://openalex.org/S45848134","display_name":"Journal of Systems Science and Complexity","issn_l":"1009-6124","issn":["1009-6124","1559-7067"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Systems Science and Complexity","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Climate action","id":"https://metadata.un.org/sdg/13","score":0.5400000214576721}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W1485942758","https://openalex.org/W1970070519","https://openalex.org/W1970661255","https://openalex.org/W1993592538","https://openalex.org/W2007830928","https://openalex.org/W2011245122","https://openalex.org/W2021830140","https://openalex.org/W2023145868","https://openalex.org/W2033736814","https://openalex.org/W2064489283","https://openalex.org/W2171994731"],"related_works":["https://openalex.org/W2789936093","https://openalex.org/W1603824164","https://openalex.org/W1998677285","https://openalex.org/W2897954926","https://openalex.org/W4230360037","https://openalex.org/W2771707358","https://openalex.org/W4250776960","https://openalex.org/W2106469366","https://openalex.org/W2899244556","https://openalex.org/W2051497876"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-07-27T08:26:11.824852","created_date":"2025-10-10T00:00:00"}