{"id":"https://openalex.org/W1469133587","doi":"https://doi.org/10.1007/s11047-015-9508-3","title":"Halting the hallmarks: a cellular automaton model of early cancer growth inhibition","display_name":"Halting the hallmarks: a cellular automaton model of early cancer growth inhibition","publication_year":2015,"publication_date":"2015-07-24","ids":{"openalex":"https://openalex.org/W1469133587","doi":"https://doi.org/10.1007/s11047-015-9508-3","mag":"1469133587"},"language":"en","primary_location":{"id":"doi:10.1007/s11047-015-9508-3","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11047-015-9508-3","pdf_url":null,"source":{"id":"https://openalex.org/S149828480","display_name":"Natural Computing","issn_l":"1567-7818","issn":["1567-7818","1572-9796"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Natural Computing","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5011347521","display_name":"Jenna Butler","orcid":"https://orcid.org/0000-0002-0881-3028"},"institutions":[{"id":"https://openalex.org/I125749732","display_name":"Western University","ror":"https://ror.org/02grkyz14","country_code":"CA","type":"education","lineage":["https://openalex.org/I125749732"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Jenna Butler","raw_affiliation_strings":["Department of Computer Science, Middlesex College University of Western Ontario, London, ON, Canada","Department of Computer Science, Middlesex College, University of Western Ontario, London, Canada"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Middlesex College University of Western Ontario, London, ON, Canada","institution_ids":["https://openalex.org/I125749732"]},{"raw_affiliation_string":"Department of Computer Science, Middlesex College, University of Western Ontario, London, Canada","institution_ids":["https://openalex.org/I125749732"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073535752","display_name":"Frances Mackay","orcid":null},"institutions":[{"id":"https://openalex.org/I4210116946","display_name":"Middlesex London Health Unit","ror":"https://ror.org/02e3mzq40","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I4210116946"]},{"id":"https://openalex.org/I125749732","display_name":"Western University","ror":"https://ror.org/02grkyz14","country_code":"CA","type":"education","lineage":["https://openalex.org/I125749732"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Frances Mackay","raw_affiliation_strings":["Department of Applied Mathematics, Middlesex College, University of Western Ontario, London, ON, Canada","Department of Applied Mathematics, Middlesex College, University of Western Ontario, London, Canada"],"affiliations":[{"raw_affiliation_string":"Department of Applied Mathematics, Middlesex College, University of Western Ontario, London, ON, Canada","institution_ids":["https://openalex.org/I125749732","https://openalex.org/I4210116946"]},{"raw_affiliation_string":"Department of Applied Mathematics, Middlesex College, University of Western Ontario, London, Canada","institution_ids":["https://openalex.org/I125749732"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022747444","display_name":"Colin Denniston","orcid":"https://orcid.org/0000-0002-6723-0455"},"institutions":[{"id":"https://openalex.org/I4210116946","display_name":"Middlesex London Health Unit","ror":"https://ror.org/02e3mzq40","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I4210116946"]},{"id":"https://openalex.org/I125749732","display_name":"Western University","ror":"https://ror.org/02grkyz14","country_code":"CA","type":"education","lineage":["https://openalex.org/I125749732"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Colin Denniston","raw_affiliation_strings":["Department of Applied Mathematics, Middlesex College, University of Western Ontario, London, ON, Canada","Department of Applied Mathematics, Middlesex College, University of Western Ontario, London, Canada"],"affiliations":[{"raw_affiliation_string":"Department of Applied Mathematics, Middlesex College, University of Western Ontario, London, ON, Canada","institution_ids":["https://openalex.org/I125749732","https://openalex.org/I4210116946"]},{"raw_affiliation_string":"Department of Applied Mathematics, Middlesex College, University of Western Ontario, London, Canada","institution_ids":["https://openalex.org/I125749732"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059512715","display_name":"Mark Daley","orcid":"https://orcid.org/0000-0002-6939-9772"},"institutions":[{"id":"https://openalex.org/I125749732","display_name":"Western University","ror":"https://ror.org/02grkyz14","country_code":"CA","type":"education","lineage":["https://openalex.org/I125749732"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Mark Daley","raw_affiliation_strings":["Department of Computer Science, Middlesex College University of Western Ontario, London, ON, Canada","Department of Computer Science, Middlesex College, University of Western Ontario, London, Canada"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Middlesex College University of Western Ontario, London, ON, Canada","institution_ids":["https://openalex.org/I125749732"]},{"raw_affiliation_string":"Department of Computer Science, Middlesex College, University of Western Ontario, London, Canada","institution_ids":["https://openalex.org/I125749732"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5011347521"],"corresponding_institution_ids":["https://openalex.org/I125749732"],"apc_list":{"value":2290,"currency":"EUR","value_usd":2890},"apc_paid":null,"fwci":0.335,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.5970885,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":95},"biblio":{"volume":"15","issue":"1","first_page":"15","last_page":"30"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11751","display_name":"Lattice Boltzmann Simulation Studies","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/2206","display_name":"Computational Mechanics"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11751","display_name":"Lattice Boltzmann Simulation Studies","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/2206","display_name":"Computational Mechanics"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":0.9864000082015991,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11829","display_name":"Mathematical Biology Tumor Growth","score":0.9797000288963318,"subfield":{"id":"https://openalex.org/subfields/2611","display_name":"Modeling and Simulation"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.7084834575653076},{"id":"https://openalex.org/keywords/cancer-cell","display_name":"Cancer cell","score":0.49505892395973206},{"id":"https://openalex.org/keywords/cellular-automaton","display_name":"Cellular automaton","score":0.41514289379119873},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.3995526432991028},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.36182907223701477},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.3558312952518463},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3192332983016968},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.18852218985557556},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.14738142490386963}],"concepts":[{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.7084834575653076},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.49505892395973206},{"id":"https://openalex.org/C35527583","wikidata":"https://www.wikidata.org/wiki/Q189156","display_name":"Cellular automaton","level":2,"score":0.41514289379119873},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3995526432991028},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.36182907223701477},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3558312952518463},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3192332983016968},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.18852218985557556},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.14738142490386963}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1007/s11047-015-9508-3","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11047-015-9508-3","pdf_url":null,"source":{"id":"https://openalex.org/S149828480","display_name":"Natural Computing","issn_l":"1567-7818","issn":["1567-7818","1572-9796"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Natural Computing","raw_type":"journal-article"},{"id":"pmh:oai:ir.lib.uwo.ca:brainpub-1148","is_oa":false,"landing_page_url":"https://ir.lib.uwo.ca/brainpub/150","pdf_url":null,"source":{"id":"https://openalex.org/S4306400648","display_name":"Scholarship@Western (Western University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I125749732","host_organization_name":"Western University","host_organization_lineage":["https://openalex.org/I125749732"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Brain and Mind Institute Researchers' Publications","raw_type":"article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8399999737739563}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":67,"referenced_works":["https://openalex.org/W59529993","https://openalex.org/W105318348","https://openalex.org/W175812261","https://openalex.org/W207147914","https://openalex.org/W592776629","https://openalex.org/W1495672122","https://openalex.org/W1547369459","https://openalex.org/W1590288412","https://openalex.org/W1642592182","https://openalex.org/W1664235680","https://openalex.org/W1811397878","https://openalex.org/W1967600348","https://openalex.org/W1976522396","https://openalex.org/W1977905390","https://openalex.org/W1978139448","https://openalex.org/W1981989535","https://openalex.org/W1983934840","https://openalex.org/W1996398553","https://openalex.org/W1996480660","https://openalex.org/W2009913017","https://openalex.org/W2013945372","https://openalex.org/W2015594324","https://openalex.org/W2018116689","https://openalex.org/W2021831815","https://openalex.org/W2032770280","https://openalex.org/W2034269086","https://openalex.org/W2040565895","https://openalex.org/W2042332837","https://openalex.org/W2042835353","https://openalex.org/W2046199531","https://openalex.org/W2051029378","https://openalex.org/W2064971332","https://openalex.org/W2066060292","https://openalex.org/W2067462917","https://openalex.org/W2068084778","https://openalex.org/W2068264488","https://openalex.org/W2068351971","https://openalex.org/W2076674809","https://openalex.org/W2077656376","https://openalex.org/W2082447375","https://openalex.org/W2083337908","https://openalex.org/W2086705790","https://openalex.org/W2089120635","https://openalex.org/W2098085059","https://openalex.org/W2105054044","https://openalex.org/W2105564229","https://openalex.org/W2107441200","https://openalex.org/W2117242079","https://openalex.org/W2117692326","https://openalex.org/W2127225632","https://openalex.org/W2128562119","https://openalex.org/W2133001968","https://openalex.org/W2138872698","https://openalex.org/W2139940605","https://openalex.org/W2141410747","https://openalex.org/W2142847390","https://openalex.org/W2145485696","https://openalex.org/W2146226392","https://openalex.org/W2161689979","https://openalex.org/W2166505025","https://openalex.org/W2276765591","https://openalex.org/W2317475302","https://openalex.org/W2334873176","https://openalex.org/W2404551565","https://openalex.org/W3021199392","https://openalex.org/W4241943516","https://openalex.org/W4388316717"],"related_works":["https://openalex.org/W2082860237","https://openalex.org/W2130076355","https://openalex.org/W1990804418","https://openalex.org/W1993764875","https://openalex.org/W1641042124","https://openalex.org/W2013243191","https://openalex.org/W2151865869","https://openalex.org/W2117258802","https://openalex.org/W2418239294","https://openalex.org/W2805185066"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2017,"cited_by_count":1}],"updated_date":"2026-04-05T17:49:38.594831","created_date":"2025-10-10T00:00:00"}