{"id":"https://openalex.org/W4417521058","doi":"https://doi.org/10.1007/s10916-025-02322-9","title":"Digital Twins and Health Care: an Umbrella Review","display_name":"Digital Twins and Health Care: an Umbrella Review","publication_year":2025,"publication_date":"2025-12-20","ids":{"openalex":"https://openalex.org/W4417521058","doi":"https://doi.org/10.1007/s10916-025-02322-9","pmid":"https://pubmed.ncbi.nlm.nih.gov/41420670"},"language":"en","primary_location":{"id":"doi:10.1007/s10916-025-02322-9","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10916-025-02322-9","pdf_url":null,"source":{"id":"https://openalex.org/S37151855","display_name":"Journal of Medical Systems","issn_l":"0148-5598","issn":["0148-5598","1573-689X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Medical Systems","raw_type":"journal-article"},"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113712516","display_name":"M Afshar","orcid":"https://orcid.org/0000-0001-8623-768X"},"institutions":[{"id":"https://openalex.org/I3122832768","display_name":"Kurdistan University of Medical Sciences","ror":"https://ror.org/01ntx4j68","country_code":"IR","type":"education","lineage":["https://openalex.org/I3122832768"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Maziar Afshar","raw_affiliation_strings":["Student Research Committee, Kurdistan University of Medical Sciences, Sanandaj, Iran"],"affiliations":[{"raw_affiliation_string":"Student Research Committee, Kurdistan University of Medical Sciences, Sanandaj, Iran","institution_ids":["https://openalex.org/I3122832768"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057413301","display_name":"Asra Moradkhani","orcid":"https://orcid.org/0000-0003-1443-3950"},"institutions":[{"id":"https://openalex.org/I3122832768","display_name":"Kurdistan University of Medical Sciences","ror":"https://ror.org/01ntx4j68","country_code":"IR","type":"education","lineage":["https://openalex.org/I3122832768"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Asra Moradkhani","raw_affiliation_strings":["Student Research Committee, Kurdistan University of Medical Sciences, Sanandaj, Iran"],"affiliations":[{"raw_affiliation_string":"Student Research Committee, Kurdistan University of Medical Sciences, Sanandaj, Iran","institution_ids":["https://openalex.org/I3122832768"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003987370","display_name":"Marzieh Soheili","orcid":"https://orcid.org/0000-0002-1170-2839"},"institutions":[{"id":"https://openalex.org/I19833938","display_name":"Western New England University","ror":"https://ror.org/007cnf143","country_code":"US","type":"education","lineage":["https://openalex.org/I19833938"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marzieh Soheili","raw_affiliation_strings":["College of Pharmacy, Western New England University, Springfield, MA, USA"],"affiliations":[{"raw_affiliation_string":"College of Pharmacy, Western New England University, Springfield, MA, USA","institution_ids":["https://openalex.org/I19833938"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5120866250","display_name":"Mohammadhossein Tavakkol","orcid":null},"institutions":[{"id":"https://openalex.org/I194604659","display_name":"Shiraz University of Medical Sciences","ror":"https://ror.org/01n3s4692","country_code":"IR","type":"education","lineage":["https://openalex.org/I194604659"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Mohammadhossein Tavakkol","raw_affiliation_strings":["Department of Pathology, School of Medicine, Shiraz University of Medical Sciences, Fars, Iran"],"affiliations":[{"raw_affiliation_string":"Department of Pathology, School of Medicine, Shiraz University of Medical Sciences, Fars, Iran","institution_ids":["https://openalex.org/I194604659"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077158314","display_name":"Yousef Moradi","orcid":"https://orcid.org/0000-0002-2936-5930"},"institutions":[{"id":"https://openalex.org/I3122832768","display_name":"Kurdistan University of Medical Sciences","ror":"https://ror.org/01ntx4j68","country_code":"IR","type":"education","lineage":["https://openalex.org/I3122832768"]}],"countries":["IR"],"is_corresponding":true,"raw_author_name":"Yousef Moradi","raw_affiliation_strings":["Health Metrics and Evaluation Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran. yousefmoradi211@yahoo.com","Health Metrics and Evaluation Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran"],"affiliations":[{"raw_affiliation_string":"Health Metrics and Evaluation Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran. yousefmoradi211@yahoo.com","institution_ids":["https://openalex.org/I3122832768"]},{"raw_affiliation_string":"Health Metrics and Evaluation Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran","institution_ids":["https://openalex.org/I3122832768"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5015145670","display_name":"Hamed Gilzad Kohan","orcid":"https://orcid.org/0000-0002-8028-0481"},"institutions":[{"id":"https://openalex.org/I19833938","display_name":"Western New England University","ror":"https://ror.org/007cnf143","country_code":"US","type":"education","lineage":["https://openalex.org/I19833938"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hamed Gilzad Kohan","raw_affiliation_strings":["College of Pharmacy, Western New England University, Springfield, MA, USA. hamed.gilzadkohan@wne.edu","College of Pharmacy, Western New England University, Springfield, MA, USA"],"affiliations":[{"raw_affiliation_string":"College of Pharmacy, Western New England University, Springfield, MA, USA. hamed.gilzadkohan@wne.edu","institution_ids":["https://openalex.org/I19833938"]},{"raw_affiliation_string":"College of Pharmacy, Western New England University, Springfield, MA, USA","institution_ids":["https://openalex.org/I19833938"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5077158314"],"corresponding_institution_ids":["https://openalex.org/I3122832768"],"apc_list":{"value":3390,"currency":"EUR","value_usd":4390},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.38264487,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"49","issue":"1","first_page":"186","last_page":"186"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11636","display_name":"Artificial Intelligence in Healthcare and Education","score":0.3133000135421753,"subfield":{"id":"https://openalex.org/subfields/2718","display_name":"Health Informatics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11636","display_name":"Artificial Intelligence in Healthcare and Education","score":0.3133000135421753,"subfield":{"id":"https://openalex.org/subfields/2718","display_name":"Health Informatics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10763","display_name":"Digital Transformation in Industry","score":0.2280000001192093,"subfield":{"id":"https://openalex.org/subfields/2209","display_name":"Industrial and Manufacturing Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11519","display_name":"Digital Mental Health Interventions","score":0.10329999774694443,"subfield":{"id":"https://openalex.org/subfields/3202","display_name":"Applied Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/systematic-review","display_name":"Systematic review","score":0.6818000078201294},{"id":"https://openalex.org/keywords/health-informatics","display_name":"Health informatics","score":0.6324999928474426},{"id":"https://openalex.org/keywords/health-care","display_name":"Health care","score":0.5616000294685364},{"id":"https://openalex.org/keywords/digital-health","display_name":"Digital health","score":0.5133000016212463},{"id":"https://openalex.org/keywords/healthcare-delivery","display_name":"Healthcare delivery","score":0.4788999855518341},{"id":"https://openalex.org/keywords/health-technology","display_name":"Health technology","score":0.4171999990940094},{"id":"https://openalex.org/keywords/key","display_name":"Key (lock)","score":0.4138999879360199},{"id":"https://openalex.org/keywords/inclusion","display_name":"Inclusion (mineral)","score":0.3840999901294708},{"id":"https://openalex.org/keywords/data-sharing","display_name":"Data sharing","score":0.3686999976634979}],"concepts":[{"id":"https://openalex.org/C189708586","wikidata":"https://www.wikidata.org/wiki/Q1504425","display_name":"Systematic review","level":3,"score":0.6818000078201294},{"id":"https://openalex.org/C145642194","wikidata":"https://www.wikidata.org/wiki/Q870895","display_name":"Health informatics","level":3,"score":0.6324999928474426},{"id":"https://openalex.org/C160735492","wikidata":"https://www.wikidata.org/wiki/Q31207","display_name":"Health care","level":2,"score":0.5616000294685364},{"id":"https://openalex.org/C2780433410","wikidata":"https://www.wikidata.org/wiki/Q5276090","display_name":"Digital health","level":3,"score":0.5133000016212463},{"id":"https://openalex.org/C3018457447","wikidata":"https://www.wikidata.org/wiki/Q31207","display_name":"Healthcare delivery","level":3,"score":0.4788999855518341},{"id":"https://openalex.org/C21333345","wikidata":"https://www.wikidata.org/wiki/Q1519843","display_name":"Health technology","level":3,"score":0.4171999990940094},{"id":"https://openalex.org/C26517878","wikidata":"https://www.wikidata.org/wiki/Q228039","display_name":"Key (lock)","level":2,"score":0.4138999879360199},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.40049999952316284},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4000000059604645},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.38519999384880066},{"id":"https://openalex.org/C109359841","wikidata":"https://www.wikidata.org/wiki/Q728944","display_name":"Inclusion (mineral)","level":2,"score":0.3840999901294708},{"id":"https://openalex.org/C2779965156","wikidata":"https://www.wikidata.org/wiki/Q5227350","display_name":"Data sharing","level":3,"score":0.3686999976634979},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.36090001463890076},{"id":"https://openalex.org/C32220436","wikidata":"https://www.wikidata.org/wiki/Q2072214","display_name":"Personalized medicine","level":2,"score":0.34610000252723694},{"id":"https://openalex.org/C56739046","wikidata":"https://www.wikidata.org/wiki/Q192060","display_name":"Knowledge management","level":1,"score":0.32760000228881836},{"id":"https://openalex.org/C207267971","wikidata":"https://www.wikidata.org/wiki/Q120208","display_name":"Emerging technologies","level":2,"score":0.3224000036716461},{"id":"https://openalex.org/C191630685","wikidata":"https://www.wikidata.org/wiki/Q4027615","display_name":"Informatics","level":2,"score":0.32199999690055847},{"id":"https://openalex.org/C195094911","wikidata":"https://www.wikidata.org/wiki/Q14167904","display_name":"Process management","level":1,"score":0.32179999351501465},{"id":"https://openalex.org/C2988170871","wikidata":"https://www.wikidata.org/wiki/Q11000047","display_name":"Healthcare system","level":3,"score":0.3091999888420105},{"id":"https://openalex.org/C163763905","wikidata":"https://www.wikidata.org/wiki/Q17075943","display_name":"Precision medicine","level":2,"score":0.3089999854564667},{"id":"https://openalex.org/C2777466982","wikidata":"https://www.wikidata.org/wiki/Q5227287","display_name":"Data extraction","level":3,"score":0.3084000051021576},{"id":"https://openalex.org/C118643609","wikidata":"https://www.wikidata.org/wiki/Q189210","display_name":"Web application","level":2,"score":0.2948000133037567},{"id":"https://openalex.org/C2779974597","wikidata":"https://www.wikidata.org/wiki/Q28448986","display_name":"Clinical Practice","level":2,"score":0.2808000147342682},{"id":"https://openalex.org/C19648533","wikidata":"https://www.wikidata.org/wiki/Q691640","display_name":"Evidence-based medicine","level":3,"score":0.2797999978065491},{"id":"https://openalex.org/C75684735","wikidata":"https://www.wikidata.org/wiki/Q858810","display_name":"Big data","level":2,"score":0.27959999442100525},{"id":"https://openalex.org/C123201435","wikidata":"https://www.wikidata.org/wiki/Q456632","display_name":"Information privacy","level":2,"score":0.2567000091075897},{"id":"https://openalex.org/C141330323","wikidata":"https://www.wikidata.org/wiki/Q2354820","display_name":"Evidence-based practice","level":3,"score":0.2565000057220459},{"id":"https://openalex.org/C133462117","wikidata":"https://www.wikidata.org/wiki/Q4929239","display_name":"Data collection","level":2,"score":0.25609999895095825}],"mesh":[{"descriptor_ui":"D003695","descriptor_name":"Delivery of Health Care","qualifier_ui":"Q000458","qualifier_name":"organization & administration","is_major_topic":true},{"descriptor_ui":"D003695","descriptor_name":"Delivery of Health Care","qualifier_ui":"Q000458","qualifier_name":"organization & administration","is_major_topic":true},{"descriptor_ui":"D003695","descriptor_name":"Delivery of Health Care","qualifier_ui":"Q000458","qualifier_name":"organization & administration","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016494","descriptor_name":"Computer Security","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016494","descriptor_name":"Computer Security","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016494","descriptor_name":"Computer Security","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057285","descriptor_name":"Precision Medicine","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D057285","descriptor_name":"Precision Medicine","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D057285","descriptor_name":"Precision Medicine","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1007/s10916-025-02322-9","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10916-025-02322-9","pdf_url":null,"source":{"id":"https://openalex.org/S37151855","display_name":"Journal of Medical Systems","issn_l":"0148-5598","issn":["0148-5598","1573-689X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Medical Systems","raw_type":"journal-article"},{"id":"pmid:41420670","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41420670","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of medical systems","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":127,"referenced_works":["https://openalex.org/W2001747862","https://openalex.org/W2009528181","https://openalex.org/W2032462160","https://openalex.org/W2078434774","https://openalex.org/W2079743157","https://openalex.org/W2119790985","https://openalex.org/W2147001048","https://openalex.org/W2149563115","https://openalex.org/W2283925016","https://openalex.org/W2314840118","https://openalex.org/W2414317844","https://openalex.org/W2786689981","https://openalex.org/W2804079125","https://openalex.org/W2804936719","https://openalex.org/W2918972315","https://openalex.org/W2941876953","https://openalex.org/W2954713261","https://openalex.org/W2963470017","https://openalex.org/W2963753542","https://openalex.org/W2972764124","https://openalex.org/W2974705773","https://openalex.org/W2986110703","https://openalex.org/W2991662133","https://openalex.org/W2992124668","https://openalex.org/W2996167724","https://openalex.org/W2999365564","https://openalex.org/W3001904157","https://openalex.org/W3003434773","https://openalex.org/W3006478446","https://openalex.org/W3006792194","https://openalex.org/W3006815142","https://openalex.org/W3010152544","https://openalex.org/W3015800746","https://openalex.org/W3016258185","https://openalex.org/W3017665024","https://openalex.org/W3034369038","https://openalex.org/W3036185179","https://openalex.org/W3048083848","https://openalex.org/W3048347447","https://openalex.org/W3067193962","https://openalex.org/W3081679370","https://openalex.org/W3085338664","https://openalex.org/W3089100365","https://openalex.org/W3090757058","https://openalex.org/W3092316320","https://openalex.org/W3101866789","https://openalex.org/W3103205051","https://openalex.org/W3106498328","https://openalex.org/W3111194151","https://openalex.org/W3114451864","https://openalex.org/W3118615836","https://openalex.org/W3119595909","https://openalex.org/W3134269709","https://openalex.org/W3135755054","https://openalex.org/W3137036792","https://openalex.org/W3145072389","https://openalex.org/W3154177836","https://openalex.org/W3154829890","https://openalex.org/W3157609708","https://openalex.org/W3157777676","https://openalex.org/W3157912126","https://openalex.org/W3158940634","https://openalex.org/W3159064895","https://openalex.org/W3160139595","https://openalex.org/W3160496217","https://openalex.org/W3164267812","https://openalex.org/W3170724449","https://openalex.org/W3175555721","https://openalex.org/W3175792525","https://openalex.org/W3178150555","https://openalex.org/W3184569878","https://openalex.org/W3200915061","https://openalex.org/W3207648641","https://openalex.org/W3209895839","https://openalex.org/W3215822628","https://openalex.org/W3216714190","https://openalex.org/W4200362411","https://openalex.org/W4205998355","https://openalex.org/W4206558054","https://openalex.org/W4214478937","https://openalex.org/W4220831070","https://openalex.org/W4220955203","https://openalex.org/W4220959955","https://openalex.org/W4229452663","https://openalex.org/W4280498362","https://openalex.org/W4280530924","https://openalex.org/W4281706108","https://openalex.org/W4283008633","https://openalex.org/W4285066477","https://openalex.org/W4285161674","https://openalex.org/W4291890346","https://openalex.org/W4294085826","https://openalex.org/W4308746470","https://openalex.org/W4309228249","https://openalex.org/W4309399575","https://openalex.org/W4309658279","https://openalex.org/W4319436458","https://openalex.org/W4319761860","https://openalex.org/W4320856110","https://openalex.org/W4360604082","https://openalex.org/W4365454186","https://openalex.org/W4366146403","https://openalex.org/W4367054860","https://openalex.org/W4376629006","https://openalex.org/W4379203416","https://openalex.org/W4382343852","https://openalex.org/W4382402316","https://openalex.org/W4383648003","https://openalex.org/W4384788679","https://openalex.org/W4385490465","https://openalex.org/W4386495603","https://openalex.org/W4387880578","https://openalex.org/W4388571565","https://openalex.org/W4390975365","https://openalex.org/W4391261228","https://openalex.org/W4391878438","https://openalex.org/W4392101436","https://openalex.org/W4393932231","https://openalex.org/W4395004800","https://openalex.org/W4396852756","https://openalex.org/W4399303221","https://openalex.org/W4399788468","https://openalex.org/W4400449578","https://openalex.org/W4400507813","https://openalex.org/W4401501126","https://openalex.org/W4403064328","https://openalex.org/W4403791772"],"related_works":[],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-01-25T23:04:38.658462","created_date":"2025-12-20T00:00:00"}