{"id":"https://openalex.org/W3118857047","doi":"https://doi.org/10.1007/s10916-020-01701-8","title":"Shedding Light on the Black Box: Explaining Deep Neural Network Prediction of Clinical Outcomes","display_name":"Shedding Light on the Black Box: Explaining Deep Neural Network Prediction of Clinical Outcomes","publication_year":2021,"publication_date":"2021-01-01","ids":{"openalex":"https://openalex.org/W3118857047","doi":"https://doi.org/10.1007/s10916-020-01701-8","mag":"3118857047","pmid":"https://pubmed.ncbi.nlm.nih.gov/33404886"},"language":"en","primary_location":{"id":"doi:10.1007/s10916-020-01701-8","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10916-020-01701-8","pdf_url":null,"source":{"id":"https://openalex.org/S37151855","display_name":"Journal of Medical Systems","issn_l":"0148-5598","issn":["0148-5598","1573-689X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Medical Systems","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7983057","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084025490","display_name":"Yijun Shao","orcid":"https://orcid.org/0000-0001-6419-7963"},"institutions":[{"id":"https://openalex.org/I193531525","display_name":"George Washington University","ror":"https://ror.org/00y4zzh67","country_code":"US","type":"education","lineage":["https://openalex.org/I193531525"]},{"id":"https://openalex.org/I4210154891","display_name":"Washington DC VA Medical Center","ror":"https://ror.org/050fz5z96","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210111569","https://openalex.org/I4210154891"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Yijun Shao","raw_affiliation_strings":["Biomedical Informatics Center, George Washington University, Washington, DC, USA. yshao@gwu.edu","Washington DC VA Medical Center, Washington, DC, USA. yshao@gwu.edu","Biomedical Informatics Center, George Washington University, Washington, DC, USA"],"raw_orcid":"https://orcid.org/0000-0001-6419-7963","affiliations":[{"raw_affiliation_string":"Biomedical Informatics Center, George Washington University, Washington, DC, USA. yshao@gwu.edu","institution_ids":["https://openalex.org/I193531525"]},{"raw_affiliation_string":"Washington DC VA Medical Center, Washington, DC, USA. yshao@gwu.edu","institution_ids":["https://openalex.org/I4210154891"]},{"raw_affiliation_string":"Biomedical Informatics Center, George Washington University, Washington, DC, USA","institution_ids":["https://openalex.org/I193531525"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039697026","display_name":"Yan Cheng","orcid":"https://orcid.org/0000-0001-7189-3991"},"institutions":[{"id":"https://openalex.org/I193531525","display_name":"George Washington University","ror":"https://ror.org/00y4zzh67","country_code":"US","type":"education","lineage":["https://openalex.org/I193531525"]},{"id":"https://openalex.org/I4210154891","display_name":"Washington DC VA Medical Center","ror":"https://ror.org/050fz5z96","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210111569","https://openalex.org/I4210154891"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yan Cheng","raw_affiliation_strings":["Biomedical Informatics Center, George Washington University, Washington, DC, USA","Washington DC VA Medical Center, Washington, DC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Informatics Center, George Washington University, Washington, DC, USA","institution_ids":["https://openalex.org/I193531525"]},{"raw_affiliation_string":"Washington DC VA Medical Center, Washington, DC, USA","institution_ids":["https://openalex.org/I4210154891"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070780364","display_name":"Rashmee U. Shah","orcid":"https://orcid.org/0000-0002-7823-8540"},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rashmee U. Shah","raw_affiliation_strings":["Department of Internal Medicine, University of Utah, Salt Lake City, UT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, University of Utah, Salt Lake City, UT, USA","institution_ids":["https://openalex.org/I223532165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016232569","display_name":"Charlene Weir","orcid":"https://orcid.org/0000-0002-8297-2860"},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]},{"id":"https://openalex.org/I4210089864","display_name":"VA Salt Lake City Healthcare System","ror":"https://ror.org/007fyq698","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210089864","https://openalex.org/I4210113540"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Charlene R. Weir","raw_affiliation_strings":["Department of Biomedical Informatics, University of Utah, Salt Lake City, UT, USA","VA Salt Lake City Health Care System, Salt Lake City, UT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Informatics, University of Utah, Salt Lake City, UT, USA","institution_ids":["https://openalex.org/I223532165"]},{"raw_affiliation_string":"VA Salt Lake City Health Care System, Salt Lake City, UT, USA","institution_ids":["https://openalex.org/I4210089864"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059558209","display_name":"Bruce E. Bray","orcid":"https://orcid.org/0000-0003-3963-2964"},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]},{"id":"https://openalex.org/I4210089864","display_name":"VA Salt Lake City Healthcare System","ror":"https://ror.org/007fyq698","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210089864","https://openalex.org/I4210113540"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bruce E. Bray","raw_affiliation_strings":["Department of Internal Medicine, University of Utah, Salt Lake City, UT, USA","VA Salt Lake City Health Care System, Salt Lake City, UT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, University of Utah, Salt Lake City, UT, USA","institution_ids":["https://openalex.org/I223532165"]},{"raw_affiliation_string":"VA Salt Lake City Health Care System, Salt Lake City, UT, USA","institution_ids":["https://openalex.org/I4210089864"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058747294","display_name":"Qing Zeng\u2010Treitler","orcid":"https://orcid.org/0000-0002-8353-7473"},"institutions":[{"id":"https://openalex.org/I193531525","display_name":"George Washington University","ror":"https://ror.org/00y4zzh67","country_code":"US","type":"education","lineage":["https://openalex.org/I193531525"]},{"id":"https://openalex.org/I4210154891","display_name":"Washington DC VA Medical Center","ror":"https://ror.org/050fz5z96","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210111569","https://openalex.org/I4210154891"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Qing Zeng-Treitler","raw_affiliation_strings":["Biomedical Informatics Center, George Washington University, Washington, DC, USA","Washington DC VA Medical Center, Washington, DC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Informatics Center, George Washington University, Washington, DC, USA","institution_ids":["https://openalex.org/I193531525"]},{"raw_affiliation_string":"Washington DC VA Medical Center, Washington, DC, USA","institution_ids":["https://openalex.org/I4210154891"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5084025490"],"corresponding_institution_ids":["https://openalex.org/I193531525","https://openalex.org/I4210154891"],"apc_list":{"value":3390,"currency":"EUR","value_usd":4390},"apc_paid":null,"fwci":4.231,"has_fulltext":false,"cited_by_count":42,"citation_normalized_percentile":{"value":0.94866528,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":99},"biblio":{"volume":"45","issue":"1","first_page":"5","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.9948999881744385,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.9948999881744385,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12026","display_name":"Explainable Artificial Intelligence (XAI)","score":0.9850999712944031,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11636","display_name":"Artificial Intelligence in Healthcare and Education","score":0.9746000170707703,"subfield":{"id":"https://openalex.org/subfields/2718","display_name":"Health Informatics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/deep-learning","display_name":"Deep learning","score":0.776573121547699},{"id":"https://openalex.org/keywords/black-box","display_name":"Black box","score":0.714472770690918},{"id":"https://openalex.org/keywords/artificial-neural-network","display_name":"Artificial neural network","score":0.7103328704833984},{"id":"https://openalex.org/keywords/logistic-regression","display_name":"Logistic regression","score":0.6934080719947815},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6703859567642212},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6367818117141724},{"id":"https://openalex.org/keywords/odds","display_name":"Odds","score":0.6294639110565186},{"id":"https://openalex.org/keywords/receiver-operating-characteristic","display_name":"Receiver operating characteristic","score":0.5327857732772827},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.5163365602493286},{"id":"https://openalex.org/keywords/deep-neural-networks","display_name":"Deep neural networks","score":0.44601207971572876},{"id":"https://openalex.org/keywords/representation","display_name":"Representation (politics)","score":0.41959571838378906},{"id":"https://openalex.org/keywords/regression","display_name":"Regression","score":0.4184485673904419},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.3235439360141754},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.2704008221626282},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.12126916646957397}],"concepts":[{"id":"https://openalex.org/C108583219","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep learning","level":2,"score":0.776573121547699},{"id":"https://openalex.org/C94966114","wikidata":"https://www.wikidata.org/wiki/Q29256","display_name":"Black box","level":2,"score":0.714472770690918},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.7103328704833984},{"id":"https://openalex.org/C151956035","wikidata":"https://www.wikidata.org/wiki/Q1132755","display_name":"Logistic regression","level":2,"score":0.6934080719947815},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6703859567642212},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6367818117141724},{"id":"https://openalex.org/C143095724","wikidata":"https://www.wikidata.org/wiki/Q515895","display_name":"Odds","level":3,"score":0.6294639110565186},{"id":"https://openalex.org/C58471807","wikidata":"https://www.wikidata.org/wiki/Q327120","display_name":"Receiver operating characteristic","level":2,"score":0.5327857732772827},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.5163365602493286},{"id":"https://openalex.org/C2984842247","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep neural networks","level":3,"score":0.44601207971572876},{"id":"https://openalex.org/C2776359362","wikidata":"https://www.wikidata.org/wiki/Q2145286","display_name":"Representation (politics)","level":3,"score":0.41959571838378906},{"id":"https://openalex.org/C83546350","wikidata":"https://www.wikidata.org/wiki/Q1139051","display_name":"Regression","level":2,"score":0.4184485673904419},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.3235439360141754},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.2704008221626282},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.12126916646957397},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0},{"id":"https://openalex.org/C94625758","wikidata":"https://www.wikidata.org/wiki/Q7163","display_name":"Politics","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016015","descriptor_name":"Logistic Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016015","descriptor_name":"Logistic Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016015","descriptor_name":"Logistic Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016015","descriptor_name":"Logistic Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1007/s10916-020-01701-8","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10916-020-01701-8","pdf_url":null,"source":{"id":"https://openalex.org/S37151855","display_name":"Journal of Medical Systems","issn_l":"0148-5598","issn":["0148-5598","1573-689X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Medical Systems","raw_type":"journal-article"},{"id":"pmid:33404886","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33404886","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of medical systems","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:7983057","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7983057","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"J Med Syst","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:7983057","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7983057","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"J Med Syst","raw_type":"Text"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G2218705978","display_name":null,"funder_award_id":"CRE 12\u2013315","funder_id":"https://openalex.org/F4320306127","funder_display_name":"U.S. Department of Veterans Affairs"},{"id":"https://openalex.org/G3691238093","display_name":null,"funder_award_id":"R56 AG052536","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G3852859424","display_name":null,"funder_award_id":"K08HL136850","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G4666319644","display_name":null,"funder_award_id":"CRE 12-315","funder_id":"https://openalex.org/F4320306127","funder_display_name":"U.S. Department of Veterans Affairs"},{"id":"https://openalex.org/G5832428559","display_name":null,"funder_award_id":"I01 HX002679","funder_id":"https://openalex.org/F4320306127","funder_display_name":"U.S. Department of Veterans Affairs"},{"id":"https://openalex.org/G6740856344","display_name":null,"funder_award_id":"UL1 TR001876","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G677302542","display_name":null,"funder_award_id":"R56 AG052536-01A1","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G6896684859","display_name":null,"funder_award_id":"K08 HL136850","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G7330647538","display_name":null,"funder_award_id":"CRE 12-321","funder_id":"https://openalex.org/F4320306127","funder_display_name":"U.S. Department of Veterans Affairs"},{"id":"https://openalex.org/G7795937142","display_name":null,"funder_award_id":"UL1TR001876","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320306127","display_name":"U.S. Department of Veterans Affairs","ror":"https://ror.org/05rsv9s98"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337472","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W1165382972","https://openalex.org/W1787224781","https://openalex.org/W1849277567","https://openalex.org/W1984020445","https://openalex.org/W2037097009","https://openalex.org/W2059357787","https://openalex.org/W2095116808","https://openalex.org/W2108931859","https://openalex.org/W2124518690","https://openalex.org/W2128125030","https://openalex.org/W2137080502","https://openalex.org/W2142743215","https://openalex.org/W2148638122","https://openalex.org/W2152175008","https://openalex.org/W2161381512","https://openalex.org/W2163605009","https://openalex.org/W2165719156","https://openalex.org/W2177350256","https://openalex.org/W2257979135","https://openalex.org/W2335231222","https://openalex.org/W2503179616","https://openalex.org/W2511950764","https://openalex.org/W2517582793","https://openalex.org/W2588978745","https://openalex.org/W2596720518","https://openalex.org/W2610332124","https://openalex.org/W2617669016","https://openalex.org/W2759071281","https://openalex.org/W2789520533","https://openalex.org/W2919115771","https://openalex.org/W2939880928","https://openalex.org/W2962790223","https://openalex.org/W2964006392","https://openalex.org/W2985962305","https://openalex.org/W3138819813"],"related_works":["https://openalex.org/W1604849300","https://openalex.org/W4312601715","https://openalex.org/W4377865163","https://openalex.org/W4392828243","https://openalex.org/W4312822655","https://openalex.org/W3157170264","https://openalex.org/W4298185893","https://openalex.org/W4402427143","https://openalex.org/W2896078964","https://openalex.org/W4281399026"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":11},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":5}],"updated_date":"2026-07-13T07:31:44.756512","created_date":"2025-10-10T00:00:00"}